| MeSH term | MeSH ID | Detail |
|---|---|---|
| Rabies | D011818 | 4 associated lipids |
| Ovarian Diseases | D010049 | 5 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Neoplasms, Hormone-Dependent | D009376 | 23 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Endometriosis | D004715 | 29 associated lipids |
| Endometrial Neoplasms | D016889 | 30 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
COUMESTROL
COUMESTROL is a lipid of Polyketides (PK) class. Coumestrol is associated with abnormalities such as Infertility, Renal tubular disorder, Osteoporosis, Postmenopausal, Nodule and Central precocious puberty. The involved functions are known as Process, antagonists, Accident due to exposure to weather conditions, physiological aspects and Cell Proliferation. Coumestrol often locates in Blood, Body tissue, Reproductive system, Membrane and Myometrial. The associated genes with COUMESTROL are GAPDH gene, PPID gene, pyridinoline, NODAL gene and Nitrogen fixation gene. The related lipids are enterodiol. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of COUMESTROL, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with COUMESTROL?
COUMESTROL is suspected in Infertility, Renal tubular disorder, Osteoporosis, Postmenopausal, Nodule, Central precocious puberty and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with COUMESTROL
PubChem Associated disorders and diseases
What pathways are associated with COUMESTROL
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with COUMESTROL?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with COUMESTROL?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with COUMESTROL?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with COUMESTROL?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with COUMESTROL?
Mouse Model
Mouse Model are used in the study 'Modulation of tumor formation and intestinal cell migration by estrogens in the Apc(Min/+) mouse model of colorectal cancer.' (Javid SH et al., 2005).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with COUMESTROL
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Su LJ et al. | Epigenetic Contributions to the Relationship between Cancer and Dietary Intake of Nutrients, Bioactive Food Components, and Environmental Toxicants. | 2011 | Front Genet | pmid:22303385 |
| Hoerger CC et al. | Occurrence and mass balance of isoflavones on an experimental grassland field. | 2011 | Environ. Sci. Technol. | pmid:21711017 |
| Sunita P and Pattanayak SP | Phytoestrogens in postmenopausal indications: A theoretical perspective. | 2011 | Pharmacogn Rev | pmid:22096317 |
| Wang D et al. | Puerarin suppresses invasion and vascularization of endometriosis tissue stimulated by 17β-estradiol. | 2011 | PLoS ONE | pmid:21949833 |
| Roland WS et al. | Soy isoflavones and other isoflavonoids activate the human bitter taste receptors hTAS2R14 and hTAS2R39. | 2011 | J. Agric. Food Chem. | pmid:21942422 |
| Huang Y and Liu YH | Effects of phytoestrogens on genioglossus contractile properties in ovariectomized rats exposed to chronic intermittent hypoxia may be independent of their estrogenicity. | 2011 | Eur. J. Oral Sci. | pmid:21410552 |
| Hong YH et al. | Phytoestrogenic compounds in alfalfa sprout (Medicago sativa) beyond coumestrol. | 2011 | J. Agric. Food Chem. | pmid:21158449 |
| Hirosawa RM et al. | Does radioiodine therapy in patients with differentiated thyroid cancer increase the frequency of another malignant neoplasm? | 2011 | ISRN Oncol | pmid:22084737 |
| Uchi H et al. | A clinical trial of kampo formulae for the treatment of symptoms of yusho, a poisoning caused by dioxins and related organochlorine compounds. | 2011 | Evid Based Complement Alternat Med | pmid:19996156 |
| Melo PA et al. | Ability of a synthetic coumestan to antagonize Bothrops snake venom activities. | 2010 Feb-Mar | Toxicon | pmid:19883675 |
| Kunisue T et al. | Profiles of phytoestrogens in human urine from several Asian countries. | 2010 | J. Agric. Food Chem. | pmid:20707345 |
| Wyns C et al. | Development of a high-throughput LC/APCI-MS method for the determination of thirteen phytoestrogens including gut microbial metabolites in human urine and serum. | 2010 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:20299290 |
| Reinwald S et al. | A longitudinal study of the effect of genistein on bone in two different murine models of diminished estrogen-producing capacity. | 2010 | J Osteoporos | pmid:20948578 |
| Jeng YJ et al. | Subchronic exposure to phytoestrogens alone and in combination with diethylstilbestrol - pituitary tumor induction in Fischer 344 rats. | 2010 | Nutr Metab (Lond) | pmid:20459739 |
| Choi YH et al. | Phenolic compounds from Pueraria lobata protect PC12 cells against Aβ-induced toxicity. | 2010 | Arch. Pharm. Res. | pmid:21052940 |
| Tucker HA et al. | Effect of diet on fecal and urinary estrogenic activity. | 2010 | J. Dairy Sci. | pmid:20412924 |
| Taxvig C et al. | Effects of nutrition relevant mixtures of phytoestrogens on steroidogenesis, aromatase, estrogen, and androgen activity. | 2010 | Nutr Cancer | pmid:20043267 |
| Watson CS et al. | Estrogens of multiple classes and their role in mental health disease mechanisms. | 2010 | Int J Womens Health | pmid:21072308 |
| Tamaki H et al. | Inhibitory effects of herbal extracts on breast cancer resistance protein (BCRP) and structure-inhibitory potency relationship of isoflavonoids. | 2010 | Drug Metab. Pharmacokinet. | pmid:20460823 |
| Dang Z | Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications. | 2010 | Toxicol. Lett. | pmid:19913605 |