| MeSH term | MeSH ID | Detail |
|---|---|---|
| Rabies | D011818 | 4 associated lipids |
| Ovarian Diseases | D010049 | 5 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Neoplasms, Hormone-Dependent | D009376 | 23 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Endometriosis | D004715 | 29 associated lipids |
| Endometrial Neoplasms | D016889 | 30 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
COUMESTROL
COUMESTROL is a lipid of Polyketides (PK) class. Coumestrol is associated with abnormalities such as Infertility, Renal tubular disorder, Osteoporosis, Postmenopausal, Nodule and Central precocious puberty. The involved functions are known as Process, antagonists, Accident due to exposure to weather conditions, physiological aspects and Cell Proliferation. Coumestrol often locates in Blood, Body tissue, Reproductive system, Membrane and Myometrial. The associated genes with COUMESTROL are GAPDH gene, PPID gene, pyridinoline, NODAL gene and Nitrogen fixation gene. The related lipids are enterodiol. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of COUMESTROL, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with COUMESTROL?
COUMESTROL is suspected in Infertility, Renal tubular disorder, Osteoporosis, Postmenopausal, Nodule, Central precocious puberty and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with COUMESTROL
PubChem Associated disorders and diseases
What pathways are associated with COUMESTROL
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with COUMESTROL?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with COUMESTROL?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with COUMESTROL?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with COUMESTROL?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with COUMESTROL?
Mouse Model
Mouse Model are used in the study 'Modulation of tumor formation and intestinal cell migration by estrogens in the Apc(Min/+) mouse model of colorectal cancer.' (Javid SH et al., 2005).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with COUMESTROL
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Stump DG et al. | Developmental neurotoxicity study of dietary bisphenol A in Sprague-Dawley rats. | 2010 | Toxicol. Sci. | pmid:20164145 |
| Medjakovic S et al. | Potential health-modulating effects of isoflavones and metabolites via activation of PPAR and AhR. | 2010 | Nutrients | pmid:22254019 |
| Thuillier R et al. | Interdependence of platelet-derived growth factor and estrogen-signaling pathways in inducing neonatal rat testicular gonocytes proliferation. | 2010 | Biol. Reprod. | pmid:20089883 |
| Ndebele K et al. | Estrogenic activity of coumestrol, DDT, and TCDD in human cervical cancer cells. | 2010 | Int J Environ Res Public Health | pmid:20623010 |
| Sakamoto T et al. | Effects of diverse dietary phytoestrogens on cell growth, cell cycle and apoptosis in estrogen-receptor-positive breast cancer cells. | 2010 | J. Nutr. Biochem. | pmid:19800779 |
| Hernández-Elizondo J et al. | [Exposure of phytoestrogens intake through diet in a sample of females]. | 2009 Jul-Aug | Nutr Hosp | pmid:19721924 |
| Matulka RA et al. | Developmental and Reproductive Effects of SE5-OH: An Equol-Rich Soy-Based Ingredient. | 2009 | J Toxicol | pmid:20107584 |
| Wu XT et al. | Coumestrol promotes proliferation and osteoblastic differentiation in rat bone marrow stromal cells. | 2009 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:19165772 |
| Jeng YJ and Watson CS | Proliferative and anti-proliferative effects of dietary levels of phytoestrogens in rat pituitary GH3/B6/F10 cells - the involvement of rapidly activated kinases and caspases. | 2009 | BMC Cancer | pmid:19765307 |
| Frye CA et al. | Antiseizure effects of 3alpha-androstanediol and/or 17beta-estradiol may involve actions at estrogen receptor beta. | 2009 | Epilepsy Behav | pmid:19854112 |
| Brown JS | Effects of bisphenol-A and other endocrine disruptors compared with abnormalities of schizophrenia: an endocrine-disruption theory of schizophrenia. | 2009 | Schizophr Bull | pmid:18245062 |
| Lundgren MS and Novak PJ | Quantification of phytoestrogens in industrial waste streams. | 2009 | Environ. Toxicol. Chem. | pmid:19563235 |
| Ferrer I et al. | Gas chromatographic-mass spectrometric fragmentation study of phytoestrogens as their trimethylsilyl derivatives: identification in soy milk and wastewater samples. | 2009 | J Chromatogr A | pmid:19577238 |
| Andersen C et al. | Effect of forage on the content of phyto-oestrogens in bovine milk. | 2009 | Animal | pmid:22444386 |
| Kuhnle GG et al. | Phytoestrogen content of cereals and cereal-based foods consumed in the UK. | 2009 | Nutr Cancer | pmid:19373603 |
| Hong YH et al. | The ethyl acetate extract of alfalfa sprout ameliorates disease severity of autoimmune-prone MRL-lpr/lpr mice. | 2009 | Lupus | pmid:19213858 |
| Moon HJ et al. | Lactational coumestrol exposure increases ovarian apoptosis in adult rats. | 2009 | Arch. Toxicol. | pmid:19165469 |
| Kuster M et al. | Analysis of phytoestrogens, progestogens and estrogens in environmental waters from Rio de Janeiro (Brazil). | 2009 | Environ Int | pmid:19467706 |
| González-Lamothe R et al. | Plant antimicrobial agents and their effects on plant and human pathogens. | 2009 | Int J Mol Sci | pmid:20111686 |
| Cheim LM et al. | Effect of nutritional recovery with soybean flour diet on body composition, energy balance and serum leptin concentration in adult rats. | 2009 | Nutr Metab (Lond) | pmid:19703309 |