| MeSH term | MeSH ID | Detail |
|---|---|---|
| Breast Neoplasms | D001943 | 24 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Endometriosis | D004715 | 29 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Neoplasms, Hormone-Dependent | D009376 | 23 associated lipids |
| Ovarian Diseases | D010049 | 5 associated lipids |
| Rabies | D011818 | 4 associated lipids |
| Endometrial Neoplasms | D016889 | 30 associated lipids |
COUMESTROL
COUMESTROL is a lipid of Polyketides (PK) class. Coumestrol is associated with abnormalities such as Infertility, Renal tubular disorder, Osteoporosis, Postmenopausal, Nodule and Central precocious puberty. The involved functions are known as Process, antagonists, Accident due to exposure to weather conditions, physiological aspects and Cell Proliferation. Coumestrol often locates in Blood, Body tissue, Reproductive system, Membrane and Myometrial. The associated genes with COUMESTROL are GAPDH gene, PPID gene, pyridinoline, NODAL gene and Nitrogen fixation gene. The related lipids are enterodiol. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of COUMESTROL, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with COUMESTROL?
COUMESTROL is suspected in Infertility, Renal tubular disorder, Osteoporosis, Postmenopausal, Nodule, Central precocious puberty and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with COUMESTROL
PubChem Associated disorders and diseases
What pathways are associated with COUMESTROL
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with COUMESTROL?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with COUMESTROL?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with COUMESTROL?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with COUMESTROL?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with COUMESTROL?
Mouse Model
Mouse Model are used in the study 'Modulation of tumor formation and intestinal cell migration by estrogens in the Apc(Min/+) mouse model of colorectal cancer.' (Javid SH et al., 2005).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with COUMESTROL
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Huang MH et al. | Development of an updated phytoestrogen database for use with the SWAN food frequency questionnaire: intakes and food sources in a community-based, multiethnic cohort study. | 2012 | Nutr Cancer | pmid:22211850 |
| Ueda M et al. | Effects of coumestrol administration to maternal mice during pregnancy and lactation on renal Ca metabolism in neonatal mice. | 2012 | Anim. Sci. J. | pmid:22694330 |
| Patisaul HB | Infertility in the Southern White Rhino: is diet the source of the problem? | 2012 | Endocrinology | pmid:22408178 |
| Greendale GA et al. | Dietary phytoestrogen intakes and cognitive function during the menopausal transition: results from the Study of Women's Health Across the Nation Phytoestrogen Study. | 2012 | Menopause | pmid:22415567 |
| Canal Castro C et al. | Coumestrol has neuroprotective effects before and after global cerebral ischemia in female rats. | 2012 | Brain Res. | pmid:22824334 |
| Liu B et al. | [Simultaneous determination of four kinds of furocoumarins in cosmetics by high performance liquid chromatography]. | 2012 | Wei Sheng Yan Jiu | pmid:23213695 |
| Hong H et al. | Rat α-Fetoprotein binding affinities of a large set of structurally diverse chemicals elucidated the relationships between structures and binding affinities. | 2012 | Chem. Res. Toxicol. | pmid:23013281 |
| Tubbs C et al. | Activation of southern white rhinoceros (Ceratotherium simum simum) estrogen receptors by phytoestrogens: potential role in the reproductive failure of captive-born females? | 2012 | Endocrinology | pmid:22253418 |
| Lowry SJ et al. | Mammographic breast density and serum phytoestrogen levels. | 2012 | Nutr Cancer | pmid:22860715 |
| Collodoro M et al. | Identification and quantification of concentration-dependent biomarkers in MCF-7/BOS cells exposed to 17β-estradiol by 2-D DIGE and label-free proteomics. | 2012 | J Proteomics | pmid:22580036 |
| Höjer A et al. | Effects of feeding dairy cows different legume-grass silages on milk phytoestrogen concentration. | 2012 | J. Dairy Sci. | pmid:22818467 |
| Jin SE et al. | Anti-inflammatory and antioxidant activities of constituents isolated from Pueraria lobata roots. | 2012 | Arch. Pharm. Res. | pmid:22644850 |
| Walker VR et al. | Estrogen receptor-α mediates diethylstilbestrol-induced feminization of the seminal vesicle in male mice. | 2012 | Environ. Health Perspect. | pmid:22275727 |
| Long M et al. | Effects of selected phytoestrogens and their mixtures on the function of the thyroid hormone and the aryl hydrocarbon receptor. | 2012 | Nutr Cancer | pmid:22966911 |
| Karlgren M et al. | Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | 2012 | J. Med. Chem. | pmid:22541068 |
| Aloui A et al. | Influence of arbuscular mycorrhizal colonisation on cadmium induced Medicago truncatula root isoflavonoid accumulation. | 2012 | Plant Physiol. Biochem. | pmid:23000816 |
| Jung EM et al. | Biomarker genes for detecting estrogenic activity of endocrine disruptors via estrogen receptors. | 2012 | Int J Environ Res Public Health | pmid:22690157 |
| Malherbe CJ et al. | Development of on-line high performance liquid chromatography (HPLC)-biochemical detection methods as tools in the identification of bioactives. | 2012 | Int J Mol Sci | pmid:22489144 |
| Opalka M et al. | Mechanism of phytoestrogen action in Leydig cells of ganders (Anser anser domesticus): Interaction with estrogen receptors and steroidogenic enzymes. | 2012 | J Environ Sci Health A Tox Hazard Subst Environ Eng | pmid:22540659 |
| Jeon HY et al. | Effect of Aspergillus oryzae-challenged germination on soybean isoflavone content and antioxidant activity. | 2012 | J. Agric. Food Chem. | pmid:22409158 |