COUMESTROL

COUMESTROL is a lipid of Polyketides (PK) class. Coumestrol is associated with abnormalities such as Infertility, Renal tubular disorder, Osteoporosis, Postmenopausal, Nodule and Central precocious puberty. The involved functions are known as Process, antagonists, Accident due to exposure to weather conditions, physiological aspects and Cell Proliferation. Coumestrol often locates in Blood, Body tissue, Reproductive system, Membrane and Myometrial. The associated genes with COUMESTROL are GAPDH gene, PPID gene, pyridinoline, NODAL gene and Nitrogen fixation gene. The related lipids are enterodiol. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of COUMESTROL, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with COUMESTROL?

COUMESTROL is suspected in Infertility, Renal tubular disorder, Osteoporosis, Postmenopausal, Nodule, Central precocious puberty and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with COUMESTROL

MeSH term MeSH ID Detail
Breast Neoplasms D001943 24 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Weight Gain D015430 101 associated lipids
Endometriosis D004715 29 associated lipids
Birth Weight D001724 23 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Ovarian Diseases D010049 5 associated lipids
Rabies D011818 4 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Per page 10 20 | Total 14

PubChem Associated disorders and diseases

What pathways are associated with COUMESTROL

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with COUMESTROL?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with COUMESTROL?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with COUMESTROL?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with COUMESTROL?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with COUMESTROL?

Mouse Model

Mouse Model are used in the study 'Modulation of tumor formation and intestinal cell migration by estrogens in the Apc(Min/+) mouse model of colorectal cancer.' (Javid SH et al., 2005).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with COUMESTROL

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Per page 10 20 50 100 | Total 418
Authors Title Published Journal PubMed Link
Patisaul HB Infertility in the Southern White Rhino: is diet the source of the problem? 2012 Endocrinology pmid:22408178
Greendale GA et al. Dietary phytoestrogen intakes and cognitive function during the menopausal transition: results from the Study of Women's Health Across the Nation Phytoestrogen Study. 2012 Menopause pmid:22415567
Canal Castro C et al. Coumestrol has neuroprotective effects before and after global cerebral ischemia in female rats. 2012 Brain Res. pmid:22824334
Liu B et al. [Simultaneous determination of four kinds of furocoumarins in cosmetics by high performance liquid chromatography]. 2012 Wei Sheng Yan Jiu pmid:23213695
Karieb S and Fox SW Zinc modifies the effect of phyto-oestrogens on osteoblast and osteoclast differentiation in vitro. 2012 Br. J. Nutr. pmid:22289672
Zhao E and Mu Q Phytoestrogen biological actions on Mammalian reproductive system and cancer growth. 2011 Jan-Mar Sci Pharm pmid:21617769
Carmichael SL et al. Estimated dietary phytoestrogen intake and major food sources among women during the year before pregnancy. 2011 Nutr J pmid:21978267
Su LJ et al. Epigenetic Contributions to the Relationship between Cancer and Dietary Intake of Nutrients, Bioactive Food Components, and Environmental Toxicants. 2011 Front Genet pmid:22303385
Hoerger CC et al. Occurrence and mass balance of isoflavones on an experimental grassland field. 2011 Environ. Sci. Technol. pmid:21711017
Sunita P and Pattanayak SP Phytoestrogens in postmenopausal indications: A theoretical perspective. 2011 Pharmacogn Rev pmid:22096317
Kang HJ et al. Antiproliferation and redifferentiation in thyroid cancer cell lines by polyphenol phytochemicals. 2011 J. Korean Med. Sci. pmid:21738342
Karieb S and Fox SW Phytoestrogens directly inhibit TNF-α-induced bone resorption in RAW264.7 cells by suppressing c-fos-induced NFATc1 expression. 2011 J. Cell. Biochem. pmid:21268069
Wang D et al. Puerarin suppresses invasion and vascularization of endometriosis tissue stimulated by 17β-estradiol. 2011 PLoS ONE pmid:21949833
Roland WS et al. Soy isoflavones and other isoflavonoids activate the human bitter taste receptors hTAS2R14 and hTAS2R39. 2011 J. Agric. Food Chem. pmid:21942422
Hong YH et al. Phytoestrogenic compounds in alfalfa sprout (Medicago sativa) beyond coumestrol. 2011 J. Agric. Food Chem. pmid:21158449
Kim JE et al. Does Glycine max leaves or Garcinia Cambogia promote weight-loss or lower plasma cholesterol in overweight individuals: a randomized control trial. 2011 Nutr J pmid:21936892
Guan XY et al. HPLC-DAD-MS(n) analysis and HPLC quantitation of chemical constituents in Xian-ling-gu-bao capsules. 2011 J Pharm Biomed Anal pmid:21477963
Hirosawa RM et al. Does radioiodine therapy in patients with differentiated thyroid cancer increase the frequency of another malignant neoplasm? 2011 ISRN Oncol pmid:22084737
Uchi H et al. A clinical trial of kampo formulae for the treatment of symptoms of yusho, a poisoning caused by dioxins and related organochlorine compounds. 2011 Evid Based Complement Alternat Med pmid:19996156
Bandera EV et al. Phytoestrogen consumption from foods and supplements and epithelial ovarian cancer risk: a population-based case control study. 2011 BMC Womens Health pmid:21943063