| MeSH term | MeSH ID | Detail |
|---|---|---|
| Breast Neoplasms | D001943 | 24 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Endometriosis | D004715 | 29 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Neoplasms, Hormone-Dependent | D009376 | 23 associated lipids |
| Ovarian Diseases | D010049 | 5 associated lipids |
| Rabies | D011818 | 4 associated lipids |
| Endometrial Neoplasms | D016889 | 30 associated lipids |
COUMESTROL
COUMESTROL is a lipid of Polyketides (PK) class. Coumestrol is associated with abnormalities such as Infertility, Renal tubular disorder, Osteoporosis, Postmenopausal, Nodule and Central precocious puberty. The involved functions are known as Process, antagonists, Accident due to exposure to weather conditions, physiological aspects and Cell Proliferation. Coumestrol often locates in Blood, Body tissue, Reproductive system, Membrane and Myometrial. The associated genes with COUMESTROL are GAPDH gene, PPID gene, pyridinoline, NODAL gene and Nitrogen fixation gene. The related lipids are enterodiol. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of COUMESTROL, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with COUMESTROL?
COUMESTROL is suspected in Infertility, Renal tubular disorder, Osteoporosis, Postmenopausal, Nodule, Central precocious puberty and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with COUMESTROL
PubChem Associated disorders and diseases
What pathways are associated with COUMESTROL
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with COUMESTROL?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with COUMESTROL?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with COUMESTROL?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with COUMESTROL?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with COUMESTROL?
Mouse Model
Mouse Model are used in the study 'Modulation of tumor formation and intestinal cell migration by estrogens in the Apc(Min/+) mouse model of colorectal cancer.' (Javid SH et al., 2005).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with COUMESTROL
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lee HI et al. | Effect of soybean coumestrol on Bradyrhizobium japonicum nodulation ability, biofilm formation, and transcriptional profile. | 2012 | Appl. Environ. Microbiol. | pmid:22307307 |
| Karieb S and Fox SW | Zinc modifies the effect of phyto-oestrogens on osteoblast and osteoclast differentiation in vitro. | 2012 | Br. J. Nutr. | pmid:22289672 |
| Cassetta A et al. | Insights into subtle conformational differences in the substrate-binding loop of fungal 17β-hydroxysteroid dehydrogenase: a combined structural and kinetic approach. | 2012 | Biochem. J. | pmid:21929506 |
| Zhang DW et al. | Solalyratins A and B, new anti-inflammatory metabolites from Solanum lyratum. | 2012 | J Nat Med | pmid:21898133 |
| Axon A et al. | Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity. | 2012 | Toxicology | pmid:22562034 |
| Zhao E and Mu Q | Phytoestrogen biological actions on Mammalian reproductive system and cancer growth. | 2011 Jan-Mar | Sci Pharm | pmid:21617769 |
| Su LJ et al. | Epigenetic Contributions to the Relationship between Cancer and Dietary Intake of Nutrients, Bioactive Food Components, and Environmental Toxicants. | 2011 | Front Genet | pmid:22303385 |
| Hoerger CC et al. | Occurrence and mass balance of isoflavones on an experimental grassland field. | 2011 | Environ. Sci. Technol. | pmid:21711017 |
| Sunita P and Pattanayak SP | Phytoestrogens in postmenopausal indications: A theoretical perspective. | 2011 | Pharmacogn Rev | pmid:22096317 |
| Kang HJ et al. | Antiproliferation and redifferentiation in thyroid cancer cell lines by polyphenol phytochemicals. | 2011 | J. Korean Med. Sci. | pmid:21738342 |
| Wang D et al. | Puerarin suppresses invasion and vascularization of endometriosis tissue stimulated by 17β-estradiol. | 2011 | PLoS ONE | pmid:21949833 |
| Roland WS et al. | Soy isoflavones and other isoflavonoids activate the human bitter taste receptors hTAS2R14 and hTAS2R39. | 2011 | J. Agric. Food Chem. | pmid:21942422 |
| Kirihata Y et al. | Effects of coumestrol administration to pregnant and lactating mice on intestinal alkaline phosphatase activity. | 2011 | Phytother Res | pmid:21031635 |
| Liu MH et al. | The protective effects of coumestrol against amyloid-β peptide- and lipopolysaccharide-induced toxicity on mice astrocytes. | 2011 | Neurol. Res. | pmid:21708076 |
| Huang Y and Liu YH | Effects of phytoestrogens on genioglossus contractile properties in ovariectomized rats exposed to chronic intermittent hypoxia may be independent of their estrogenicity. | 2011 | Eur. J. Oral Sci. | pmid:21410552 |
| Hong YH et al. | Phytoestrogenic compounds in alfalfa sprout (Medicago sativa) beyond coumestrol. | 2011 | J. Agric. Food Chem. | pmid:21158449 |
| Kim JE et al. | Does Glycine max leaves or Garcinia Cambogia promote weight-loss or lower plasma cholesterol in overweight individuals: a randomized control trial. | 2011 | Nutr J | pmid:21936892 |
| Guan XY et al. | HPLC-DAD-MS(n) analysis and HPLC quantitation of chemical constituents in Xian-ling-gu-bao capsules. | 2011 | J Pharm Biomed Anal | pmid:21477963 |
| Hirosawa RM et al. | Does radioiodine therapy in patients with differentiated thyroid cancer increase the frequency of another malignant neoplasm? | 2011 | ISRN Oncol | pmid:22084737 |
| Uchi H et al. | A clinical trial of kampo formulae for the treatment of symptoms of yusho, a poisoning caused by dioxins and related organochlorine compounds. | 2011 | Evid Based Complement Alternat Med | pmid:19996156 |