Brazilin

Brazilin is a lipid of Polyketides (PK) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 476 references associated with Brazilin in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Brazilin

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Brazilin

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Glioblastoma D005909 27 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Total 3

NCBI Entrez Crosslinks

All references with Brazilin

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Authors Title Published Journal PubMed Link
Hu CM et al. Heme oxygenase-1 mediates the inhibitory actions of brazilin in RAW264.7 macrophages stimulated with lipopolysaccharide. 2009 J Ethnopharmacol pmid:18983903
Cooksey C Hematoxylin and related compounds--an annotated bibliography concerning their origin, properties, chemistry, and certain applications. 2010 Biotech Histochem pmid:19568968
Sasaki Y et al. Vasorelaxant activity of Sappan Lignum constituents and extracts on rat aorta and mesenteric artery. 2010 Biol. Pharm. Bull. pmid:20823574
Chen Y et al. [Quality standard of Sappan Lignum]. 2010 Zhongguo Zhong Yao Za Zhi pmid:21046730
Xu P et al. Separation of four homoisoflavonoids from Caesalpinia sappan by high-speed counter-current chromatography. 2012 May-Jun Phytochem Anal pmid:21853494
Lee YR et al. Brazilin inhibits UVB-induced MMP-1/3 expressions and secretions by suppressing the NF-κB pathway in human dermal fibroblasts. 2012 Eur. J. Pharmacol. pmid:22044921
Lee CC et al. Antiallergic asthma properties of brazilin through inhibition of TH2 responses in T cells and in a murine model of asthma. 2012 J. Agric. Food Chem. pmid:22920671
Kim B et al. Brazilin induces apoptosis and G2/M arrest via inactivation of histone deacetylase in multiple myeloma U266 cells. 2012 J. Agric. Food Chem. pmid:22967175
Deng Z et al. A validated LC-MS/MS method for rapid determination of brazilin in rat plasma and its application to a pharmacokinetic study. 2013 Biomed. Chromatogr. pmid:23303567
Chang Y et al. Brazilin isolated from Caesalpinia sappan L. acts as a novel collagen receptor agonist in human platelets. 2013 J. Biomed. Sci. pmid:23350663
Lee DY et al. Brazilin inhibits growth and induces apoptosis in human glioblastoma cells. 2013 Molecules pmid:23429418
Bhakta D et al. Interaction of plant pigment brazilin with synthetic and natural DNA: spectroscopic and in silico perspective. 2013 Interdiscip Sci pmid:23605640
Wang X et al. Enantioselective total synthesis of (+)-brazilin, (-)-brazilein and (+)-brazilide A. 2013 Chem. Commun. (Camb.) pmid:23657435
Tong XZ et al. An LC/MS/MS method for simultaneous quantitation of two homoisoflavones: protosappanin B and brazilin with hypoglycemic activity in rat plasma and its application to a comparative pharmacokinetic study in normal and streptozotocin-treated rats. 2013 J Ethnopharmacol pmid:23707335
Jia Y et al. Application of a liquid chromatography-tandem mass spectrometry method to the pharmacokinetics, tissue distribution and excretion studies of brazilin in rats. 2013 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:23777611
Yan-yan J et al. A simple high-performance liquid chromatographic method for the determination of brazilin and its application to a pharmacokinetic study in rats. 2014 J Ethnopharmacol pmid:24095700
Lu Y et al. Analysis of brazilin and protosappanin B in sappan lignum by capillary zone electrophoresis with acid barrage stacking. 2013 Electrophoresis pmid:24150968
Guo J et al. Inhibitory effects of Brazilin on the vascular smooth muscle cell proliferation and migration induced by PDGF-BB. 2013 Am. J. Chin. Med. pmid:24228601
Puchtler H et al. Application of current chemical concepts to metal-hematein and -brazilein stains. 1986 Histochemistry pmid:2430916
Zuo GY et al. Synergy of aminoglycoside antibiotics by 3-Benzylchroman derivatives from the Chinese drug Caesalpinia sappan against clinical methicillin-resistant Staphylococcus aureus (MRSA). 2014 Phytomedicine pmid:24703330