| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
Total
3
Brazilin
Brazilin is a lipid of Polyketides (PK) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 476 references associated with Brazilin in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Brazilin
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Brazilin
NCBI Entrez Crosslinks
All references with Brazilin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kim SG et al. | Brazilin inhibits activities of protein kinase C and insulin receptor serine kinase in rat liver. | 1998 | Arch. Pharm. Res. | pmid:9875421 |
| Hwang GS et al. | Effects of Brazilin on the phospholipase A2 activity and changes of intracellular free calcium concentration in rat platelets. | 1998 | Arch. Pharm. Res. | pmid:9868555 |
| Mok MS et al. | Effects of Brazilin on induction of immunological tolerance by sheep red blood cells in C57BL/6 female mice. | 1998 | Arch. Pharm. Res. | pmid:9868554 |
| Choi SY et al. | Brazilin modulates immune function mainly by augmenting T cell activity in halothane administered mice. | 1997 | Planta Med. | pmid:9342942 |
| Choi SY and Moon CK | Effects of brazilin on the altered immune functions in the early phase of halothane intoxication of C57BL/6 mice. | 1997 | Planta Med. | pmid:9342941 |
| Khil LY et al. | Effects of calcium on brazilin-induced glucose transport in isolated rat epididymal adipocytes. | 1997 | Biochem. Pharmacol. | pmid:9296355 |
| Moon CK et al. | Effects of Brazilin on glucose oxidation, lipogenesis and therein involved enzymes in adipose tissues from diabetic KK-mice. | 1993 | Life Sci. | pmid:8412489 |
| Kim YM et al. | Brazilin stimulates the glucose transport in 3T3-L1 cells. | 1995 | Planta Med. | pmid:7480173 |
| Nagai M et al. | [Sappanchalcone from Caesalpinia sappan L., the proposed biosynthetic precursor of brazilin]. | 1984 | Yakugaku Zasshi | pmid:6527222 |
| Moon CK et al. | Inhibition of lens-aldose reductase activity by brazilin and haematoxylin. | 1985 | Planta Med. | pmid:3925476 |
| Hwang HS and Shim JH | Brazilin and Caesalpinia sappan L. extract protect epidermal keratinocytes from oxidative stress by inducing the expression of GPX7. | 2018 | Chin J Nat Med | pmid:29576056 |
| Park MN et al. | Review of Natural Product-Derived Compounds as Potent Antiglioblastoma Drugs. | 2017 | Biomed Res Int | pmid:29181405 |
| Guo J et al. | Brazilin inhibits the Zn-mediated aggregation of amyloid β-protein and alleviates cytotoxicity. | 2017 | J. Inorg. Biochem. | pmid:28972932 |
| Lee EB et al. | Lifespan-extending and stress resistance properties of brazilin from Caesalpinia sappan in Caenorhabditis elegans. | 2017 | Arch. Pharm. Res. | pmid:28667441 |
| Li ZY et al. | Brazilin Ameliorates Diabetic Nephropathy and Inflammation in db/db Mice. | 2017 | Inflammation | pmid:28497277 |
| Li M et al. | Brazilin Inhibits Prostatic Acidic Phosphatase Fibrillogenesis and Decreases its Cytotoxicity. | 2017 | Chem Asian J | pmid:28303660 |
| Maynez-Rojas MA et al. | Identification of natural red and purple dyes on textiles by Fiber-optics Reflectance Spectroscopy. | 2017 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:28199929 |
| He ZJ et al. | Inhibiting ROS-NF-κB-dependent autophagy enhanced brazilin-induced apoptosis in head and neck squamous cell carcinoma. | 2017 | Food Chem. Toxicol. | pmid:28063998 |
| Jia Y et al. | Brazilin exerts protective effects against renal ischemia-reperfusion injury by inhibiting the NF-κB signaling pathway. | 2016 | Int. J. Mol. Med. | pmid:27247107 |
| Siriangkhawut W et al. | A Green Sequential Injection Spectrophotometric Approach Using Natural Reagent Extracts from Heartwood of Ceasalpinia sappan Linn. for Determination of Aluminium. | 2016 | Anal Sci | pmid:26960614 |
| Yan Y et al. | Brazilin isolated from the heartwood of Caesalpinia sappan L induces endothelium-dependent and -independent relaxation of rat aortic rings. | 2015 | Acta Pharmacol. Sin. | pmid:26564314 |
| Kim J et al. | Inhibitory effect of brazilin on osteoclast differentiation and its mechanism of action. | 2015 | Int. Immunopharmacol. | pmid:26428849 |
| Lee H et al. | Brazilin Limits Inflammatory Responses through Induction of Prosurvival Autophagy in Rheumatoid Fibroblast-Like Synoviocytes. | 2015 | PLoS ONE | pmid:26295477 |
| Xu YY and Yin J | Contact dermatitis caused by brazilin in Caesalpinia sappan. | 2015 | Contact Derm. | pmid:25960163 |
| Gao XJ et al. | Brazilin plays an anti-inflammatory role with regulating Toll-like receptor 2 and TLR 2 downstream pathways in Staphylococcus aureus-induced mastitis in mice. | 2015 | Int. Immunopharmacol. | pmid:25939535 |
| Jung EG et al. | Brazilin isolated from Caesalpinia sappan L. inhibits rheumatoid arthritis activity in a type-II collagen induced arthritis mouse model. | 2015 | BMC Complement Altern Med | pmid:25896410 |
| Dapson RW and Bain CL | Brazilwood, sappanwood, brazilin and the red dye brazilein: from textile dyeing and folk medicine to biological staining and musical instruments. | 2015 | Biotech Histochem | pmid:25893688 |
| Zhang T et al. | c-Fos is involved in inhibition of human bladder carcinoma T24 cells by brazilin. | 2015 | IUBMB Life | pmid:25865820 |
| Nirmal NP and Panichayupakaranant P | Antioxidant, antibacterial, and anti-inflammatory activities of standardized brazilin-rich Caesalpinia sappan extract. | 2015 | Pharm Biol | pmid:25864864 |
| Subba Reddy BV et al. | A novel domino cyclization for the stereoselective synthesis of indeno[2,1-c]pyran and cyclopenta[c]pyran derivatives. | 2015 | Org. Biomol. Chem. | pmid:25804904 |
| Jung Y and Kim I | A concise synthetic approach to brazilin via Pd-catalyzed allylic arylation. | 2015 | Org. Biomol. Chem. | pmid:25767080 |
| Tewtrakul S et al. | Antiinflammatory and Wound Healing Effects of Caesalpinia sappan L. | 2015 | Phytother Res | pmid:25760294 |
| Du WJ et al. | Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity. | 2015 | Sci Rep | pmid:25613018 |
| Jung Y and Kim I | Total synthesis of brazilin. | 2015 | J. Org. Chem. | pmid:25562504 |
| Kim SH et al. | Brazilin Isolated from Caesalpinia sappan suppresses nuclear envelope reassembly by inhibiting barrier-to-autointegration factor phosphorylation. | 2015 | J. Pharmacol. Exp. Ther. | pmid:25369797 |
| Uddin GM et al. | One-step isolation of sappanol and brazilin from Caesalpinia sappan and their effects on oxidative stress-induced retinal death. | 2015 | BMB Rep | pmid:25248564 |
| Ananth S et al. | Performance of Caesalpinia sappan heartwood extract as photo sensitizer for dye sensitized solar cells. | 2015 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:25233024 |
| Zhang Q et al. | Inhibitory activities of Lignum Sappan extractives on growth and growth-related signaling of tumor cells. | 2014 | Chin J Nat Med | pmid:25156286 |
| Nirmal NP and Panichayupakaranant P | Anti-Propionibacterium acnes assay-guided purification of brazilin and preparation of brazilin rich extract from Caesalpinia sappan heartwood. | 2014 | Pharm Biol | pmid:24963948 |
| Jeon J et al. | Brazilin selectively disrupts proximal IL-1 receptor signaling complex formation by targeting an IKK-upstream signaling components. | 2014 | Biochem. Pharmacol. | pmid:24735611 |
| Jayakumar T et al. | Brazilin ameliorates high glucose-induced vascular inflammation via inhibiting ROS and CAMs production in human umbilical vein endothelial cells. | 2014 | Biomed Res Int | pmid:24716195 |
| Zuo GY et al. | Synergy of aminoglycoside antibiotics by 3-Benzylchroman derivatives from the Chinese drug Caesalpinia sappan against clinical methicillin-resistant Staphylococcus aureus (MRSA). | 2014 | Phytomedicine | pmid:24703330 |
| Puchtler H et al. | Application of current chemical concepts to metal-hematein and -brazilein stains. | 1986 | Histochemistry | pmid:2430916 |
| Guo J et al. | Inhibitory effects of Brazilin on the vascular smooth muscle cell proliferation and migration induced by PDGF-BB. | 2013 | Am. J. Chin. Med. | pmid:24228601 |
| Lu Y et al. | Analysis of brazilin and protosappanin B in sappan lignum by capillary zone electrophoresis with acid barrage stacking. | 2013 | Electrophoresis | pmid:24150968 |
| Yan-yan J et al. | A simple high-performance liquid chromatographic method for the determination of brazilin and its application to a pharmacokinetic study in rats. | 2014 | J Ethnopharmacol | pmid:24095700 |
| Jia Y et al. | Application of a liquid chromatography-tandem mass spectrometry method to the pharmacokinetics, tissue distribution and excretion studies of brazilin in rats. | 2013 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:23777611 |
| Tong XZ et al. | An LC/MS/MS method for simultaneous quantitation of two homoisoflavones: protosappanin B and brazilin with hypoglycemic activity in rat plasma and its application to a comparative pharmacokinetic study in normal and streptozotocin-treated rats. | 2013 | J Ethnopharmacol | pmid:23707335 |
| Wang X et al. | Enantioselective total synthesis of (+)-brazilin, (-)-brazilein and (+)-brazilide A. | 2013 | Chem. Commun. (Camb.) | pmid:23657435 |
| Bhakta D et al. | Interaction of plant pigment brazilin with synthetic and natural DNA: spectroscopic and in silico perspective. | 2013 | Interdiscip Sci | pmid:23605640 |