| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
Total
3
Brazilin
Brazilin is a lipid of Polyketides (PK) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 476 references associated with Brazilin in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Brazilin
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Brazilin
NCBI Entrez Crosslinks
All references with Brazilin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lee DY et al. | Brazilin inhibits growth and induces apoptosis in human glioblastoma cells. | 2013 | Molecules | pmid:23429418 |
| Chang Y et al. | Brazilin isolated from Caesalpinia sappan L. acts as a novel collagen receptor agonist in human platelets. | 2013 | J. Biomed. Sci. | pmid:23350663 |
| Deng Z et al. | A validated LC-MS/MS method for rapid determination of brazilin in rat plasma and its application to a pharmacokinetic study. | 2013 | Biomed. Chromatogr. | pmid:23303567 |
| Kim B et al. | Brazilin induces apoptosis and G2/M arrest via inactivation of histone deacetylase in multiple myeloma U266 cells. | 2012 | J. Agric. Food Chem. | pmid:22967175 |
| Lee CC et al. | Antiallergic asthma properties of brazilin through inhibition of TH2 responses in T cells and in a murine model of asthma. | 2012 | J. Agric. Food Chem. | pmid:22920671 |
| Lee YR et al. | Brazilin inhibits UVB-induced MMP-1/3 expressions and secretions by suppressing the NF-κB pathway in human dermal fibroblasts. | 2012 | Eur. J. Pharmacol. | pmid:22044921 |
| Xu P et al. | Separation of four homoisoflavonoids from Caesalpinia sappan by high-speed counter-current chromatography. | 2012 May-Jun | Phytochem Anal | pmid:21853494 |
| Chen Y et al. | [Quality standard of Sappan Lignum]. | 2010 | Zhongguo Zhong Yao Za Zhi | pmid:21046730 |
| Sasaki Y et al. | Vasorelaxant activity of Sappan Lignum constituents and extracts on rat aorta and mesenteric artery. | 2010 | Biol. Pharm. Bull. | pmid:20823574 |
| Cooksey C | Hematoxylin and related compounds--an annotated bibliography concerning their origin, properties, chemistry, and certain applications. | 2010 | Biotech Histochem | pmid:19568968 |
| Hu CM et al. | Heme oxygenase-1 mediates the inhibitory actions of brazilin in RAW264.7 macrophages stimulated with lipopolysaccharide. | 2009 | J Ethnopharmacol | pmid:18983903 |
| Choi BM et al. | Brazilin and the extract from Caesalpinia sappan L. protect oxidative injury through the expression of heme oxygenase-1. | 2007 | Biofactors | pmid:18525109 |
| Choi BM and Kim BR | Upregulation of heme oxygenase-1 by brazilin via the phosphatidylinositol 3-kinase/Akt and ERK pathways and its protective effect against oxidative injury. | 2008 | Eur. J. Pharmacol. | pmid:18021765 |
| Sasaki Y et al. | In vitro study for inhibition of NO production about constituents of Sappan Lignum. | 2007 | Biol. Pharm. Bull. | pmid:17202686 |
| Rázga Z and Gábor M | [Edema inhibiting effect of indenochromene derivatives from natural sources]. | 1990 | Acta Pharm Hung | pmid:1691574 |
| Yun J et al. | Formation of Cu(II)-brazilin complex in the presence of DNA and its activities as chemical nuclease. | 2006 | J. Inorg. Biochem. | pmid:16797715 |
| Huang Y et al. | Synthesis of (+/-)-brazilin using IBX. | 2005 | Org. Lett. | pmid:16354080 |
| Hulme AN et al. | Negative ion electrospray mass spectrometry of neoflavonoids. | 2005 | Phytochemistry | pmid:16242737 |
| Kwak WJ et al. | Effects of Brx-019 (acetic acid 3,6a,9-triacetoxy-6,6a,7, 11b-tetrahydro-indeno [2,1-c] chromen-10-yl ester), a Brazilin derivative, on T cell-mediated immune responses in multiple low dose streptozotocin-induced diabetic C57BL/6 male mice. | 2005 | Arzneimittelforschung | pmid:16229119 |
| You EJ et al. | Effects of brazilin on the production of fructose-2,6-bisphosphate in rat hepatocytes. | 2005 | J Ethnopharmacol | pmid:15994045 |
| Bae IK et al. | Suppression of lipopolysaccharide-induced expression of inducible nitric oxide synthase by brazilin in RAW 264.7 macrophage cells. | 2005 | Eur. J. Pharmacol. | pmid:15862806 |
| Lee GY et al. | Antiplatelet activity of BRX-018, (6aS,cis)-malonic acid 3-acetoxy-6a9-bis-(2-methoxycarbonyl-acetoxy)-6,6a,7,11b-tetrahydro-indeno[2,1-c]chromen-10-yl ester methylester. | 2005 | Thromb. Res. | pmid:15668191 |
| Moon CK et al. | Brazilin protects cultured rat hepatocytes from BrCCl3-induced toxicity. | 1992 | Drug Chem Toxicol | pmid:1555525 |
| Xu HX and Lee SF | The antibacterial principle of Caesalpina sappan. | 2004 | Phytother Res | pmid:15476302 |
| Won HS et al. | Mechanism of action of Brazilin on gluconeogenesis in isolated rat hepatocytes. | 2004 | Planta Med. | pmid:15368663 |
| Hu CM et al. | Induction of vasorelaxation through activation of nitric oxide synthase in endothelial cells by brazilin. | 2003 | Eur. J. Pharmacol. | pmid:12729841 |
| Mar W et al. | A DNA strand-nicking principle of a higher plant, Caesalpinia sappan. | 2003 | Arch. Pharm. Res. | pmid:12643592 |
| Yang KM et al. | Brazilin augments cellular immunity in multiple low dose streptozotocin (MLD-STZ) induced type I diabetic mice. | 2000 | Arch. Pharm. Res. | pmid:11156186 |
| Xie YW et al. | Vasorelaxing effects of Caesalpinia sappan involvement of endogenous nitric oxide. | 2000 | Life Sci. | pmid:11043613 |
| Khil LY et al. | Effects of brazilin on GLUT4 recruitment in isolated rat epididymal adipocytes. | 1999 | Biochem. Pharmacol. | pmid:10571244 |
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