HEMATOXYLIN is a lipid of Polyketides (PK) class. Hematoxylin is associated with abnormalities such as Eosinophilia, Duodenal Adenoma, Senile Plaques, Morphologically altered structure and Cervical abscess. The involved functions are known as Uptake, Apoptosis, Amplification, Necrosis and Karyopyknosis. Hematoxylin often locates in Body tissue, Extracellular, Compact bone, Skin and Basement membrane. The associated genes with HEMATOXYLIN are GAPDH gene, Genome, Elastin, MERTK wt Allele and P4HTM gene.
To understand associated biological information of HEMATOXYLIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
HEMATOXYLIN is suspected in Senile Plaques, Eosinophilia, Duodenal Adenoma, Morphologically altered structure, Cervical abscess and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with HEMATOXYLIN
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Bradley G et al. | The expression of p53-induced protein with death domain (Pidd) and apoptosis in oral squamous cell carcinoma. | 2007 | Br. J. Cancer | pmid:17437012 |
Hsieh JL et al. | Gene therapy for bladder cancer using E1B-55 kD-deleted adenovirus in combination with adenoviral vector encoding plasminogen kringles 1-5. | 2003 | Br. J. Cancer | pmid:12778082 |
Beau-Faller M et al. | Detection of K-Ras mutations in tumour samples of patients with non-small cell lung cancer using PNA-mediated PCR clamping. | 2009 | Br. J. Cancer | pmid:19293811 |
Terry G et al. | The role of human papillomavirus type 16 and the fragile histidine triad gene in the outcome of cervical neoplastic lesions. | 2004 | Br. J. Cancer | pmid:15570308 |
Couvelard A et al. | Microvascular density and hypoxia-inducible factor pathway in pancreatic endocrine tumours: negative correlation of microvascular density and VEGF expression with tumour progression. | 2005 | Br. J. Cancer | pmid:15558070 |
Kupryjańczyk J et al. | Evaluation of clinical significance of TP53, BCL-2, BAX and MEK1 expression in 229 ovarian carcinomas treated with platinum-based regimen. | 2003 | Br. J. Cancer | pmid:12644821 |
Mekenkamp LJ et al. | Clinicopathological features and outcome in advanced colorectal cancer patients with synchronous vs metachronous metastases. | 2010 | Br. J. Cancer | pmid:20551951 |
Shetty G et al. | Raman spectroscopy: elucidation of biochemical changes in carcinogenesis of oesophagus. | 2006 | Br. J. Cancer | pmid:16622450 |
Ishikawa K et al. | Mitotic centromere-associated kinesin is a novel marker for prognosis and lymph node metastasis in colorectal cancer. | 2008 | Br. J. Cancer | pmid:18506187 |
Hanly AM et al. | Thrombomodulin expression in colorectal carcinoma is protective and correlates with survival. | 2006 | Br. J. Cancer | pmid:16622452 |
Bilim V et al. | Glycogen synthase kinase-3: a new therapeutic target in renal cell carcinoma. | 2009 | Br. J. Cancer | pmid:19920820 |
Scott IS et al. | A minimally invasive immunocytochemical approach to early detection of oral squamous cell carcinoma and dysplasia. | 2006 | Br. J. Cancer | pmid:16622441 |
Trinh XB et al. | The VEGF pathway and the AKT/mTOR/p70S6K1 signalling pathway in human epithelial ovarian cancer. | 2009 | Br. J. Cancer | pmid:19240722 |
Buggy Y et al. | Overexpression of the Ets-1 transcription factor in human breast cancer. | 2004 | Br. J. Cancer | pmid:15365563 |
Liu J et al. | Adenovirus-mediated hypoxia-targeting cytosine deaminase gene therapy enhances radiotherapy in tumour xenografts. | 2007 | Br. J. Cancer | pmid:17519901 |
Baldewijns MM et al. | High-grade clear cell renal cell carcinoma has a higher angiogenic activity than low-grade renal cell carcinoma based on histomorphological quantification and qRT-PCR mRNA expression profile. | 2007 | Br. J. Cancer | pmid:17505508 |
Suzuki S et al. | MAGE-A protein and MAGE-A10 gene expressions in liver metastasis in patients with stomach cancer. | 2008 | Br. J. Cancer | pmid:18594524 |
Aoyagi Y et al. | Overexpression of TGF-beta by infiltrated granulocytes correlates with the expression of collagen mRNA in pancreatic cancer. | 2004 | Br. J. Cancer | pmid:15365564 |
Kim MS et al. | Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias. | 2008 | Br. J. Cancer | pmid:18392055 |
Weinlich G et al. | Metallothionein - overexpression as a highly significant prognostic factor in melanoma: a prospective study on 1270 patients. | 2006 | Br. J. Cancer | pmid:16508630 |
Shrout J et al. | beta(2)microglobulin mRNA expression levels are prognostic for lymph node metastasis in colorectal cancer patients. | 2008 | Br. J. Cancer | pmid:18506145 |
Griffiths EA et al. | Increasing expression of hypoxia-inducible proteins in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence. | 2007 | Br. J. Cancer | pmid:17437013 |
Barker SE et al. | Immunotherapy for neuroblastoma using syngeneic fibroblasts transfected with IL-2 and IL-12. | 2007 | Br. J. Cancer | pmid:17595664 |
Tomlinson VA et al. | Expression of eEF1A2 is associated with clear cell histology in ovarian carcinomas: overexpression of the gene is not dependent on modifications at the EEF1A2 locus. | 2007 | Br. J. Cancer | pmid:17437010 |
McFadyen MC et al. | Cytochrome P450 CYP1B1 activity in renal cell carcinoma. | 2004 | Br. J. Cancer | pmid:15280921 |
Pritchard-Jones RO et al. | Expression of VEGF(xxx)b, the inhibitory isoforms of VEGF, in malignant melanoma. | 2007 | Br. J. Cancer | pmid:17595666 |
Sakamoto A et al. | Clinical implication of expression of cyclooxygenase-2 and peroxisome proliferator activated-receptor gamma in epithelial ovarian tumours. | 2004 | Br. J. Cancer | pmid:15266333 |
Lawson MH et al. | Bcl-2 and β1-integrin predict survival in a tissue microarray of small cell lung cancer. | 2010 | Br. J. Cancer | pmid:21063403 |
Kazama S et al. | Tumour budding at the deepest invasive margin correlates with lymph node metastasis in submucosal colorectal cancer detected by anticytokeratin antibody CAM5.2. | 2006 | Br. J. Cancer | pmid:16404429 |
Arnould L et al. | Trastuzumab-based treatment of HER2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism? | 2006 | Br. J. Cancer | pmid:16404427 |
Went P et al. | Frequent high-level expression of the immunotherapeutic target Ep-CAM in colon, stomach, prostate and lung cancers. | 2006 | Br. J. Cancer | pmid:16404366 |
Bingle L et al. | Macrophages promote angiogenesis in human breast tumour spheroids in vivo. | 2006 | Br. J. Cancer | pmid:16404363 |
Zheng BY et al. | Detection of adeno-associated virus type 2 genome in cervical carcinoma. | 2006 | Br. J. Cancer | pmid:16736006 |
Ben-Izhak O et al. | TUNEL - an efficient prognosis predictor of salivary malignancies. | 2007 | Br. J. Cancer | pmid:17325701 |
Julien C et al. | Assessment of vascular reactivity in rat brain glioma by measuring regional blood volume during graded hypoxic hypoxia. | 2004 | Br. J. Cancer | pmid:15188003 |
Zou L et al. | Profilin-1 is a negative regulator of mammary carcinoma aggressiveness. | 2007 | Br. J. Cancer | pmid:17940506 |
Heng B et al. | Human papilloma virus is associated with breast cancer. | 2009 | Br. J. Cancer | pmid:19724278 |
Sigstad E et al. | A prospective study of the relationship between prediagnostic human papillomavirus seropositivity and HPV DNA in subsequent cervical carcinomas. | 2002 | Br. J. Cancer | pmid:12107839 |
Griffiths EA et al. | Hypoxia-associated markers in gastric carcinogenesis and HIF-2alpha in gastric and gastro-oesophageal cancer prognosis. | 2008 | Br. J. Cancer | pmid:18283323 |
Campbell L et al. | Combined expression of caveolin-1 and an activated AKT/mTOR pathway predicts reduced disease-free survival in clinically confined renal cell carcinoma. | 2008 | Br. J. Cancer | pmid:18283322 |
Fenton BM et al. | Zonal image analysis of tumour vascular perfusion, hypoxia, and necrosis. | 2002 | Br. J. Cancer | pmid:12087474 |
Mc Cormack O et al. | Growth arrest-specific gene 6 expression in human breast cancer. | 2008 | Br. J. Cancer | pmid:18283315 |
Brown NJ et al. | Fibrinogen E fragment selectively disrupts the vasculature and inhibits the growth of tumours in a syngeneic murine model. | 2002 | Br. J. Cancer | pmid:12087471 |
Bilim V et al. | Double inhibition of XIAP and Bcl-2 axis is beneficial for retrieving sensitivity of renal cell cancer to apoptosis. | 2008 | Br. J. Cancer | pmid:18283311 |
Clemons MJ et al. | Heterogeneity of O6-alkylguanine DNA-alkyltransferase expression in human breast tumours. | 2002 | Br. J. Cancer | pmid:12087469 |
Slade MJ et al. | Comparison of bone marrow, disseminated tumour cells and blood-circulating tumour cells in breast cancer patients after primary treatment. | 2009 | Br. J. Cancer | pmid:19034279 |
Hong AM et al. | Human papillomavirus predicts outcome in oropharyngeal cancer in patients treated primarily with surgery or radiation therapy. | 2010 | Br. J. Cancer | pmid:20959828 |
Tørring N et al. | Genome-wide analysis of allelic imbalance in prostate cancer using the Affymetrix 50K SNP mapping array. | 2007 | Br. J. Cancer | pmid:17245344 |
Yun JP et al. | Increased expression of nucleophosmin/B23 in hepatocellular carcinoma and correlation with clinicopathological parameters. | 2007 | Br. J. Cancer | pmid:17245342 |
Bhagavathula N et al. | Upregulation of calcium-sensing receptor and mitogen-activated protein kinase signalling in the regulation of growth and differentiation in colon carcinoma. | 2005 | Br. J. Cancer | pmid:16278666 |
Sasiadek MM et al. | Impairment of MLH1 and CDKN2A in oncogenesis of laryngeal cancer. | 2004 | Br. J. Cancer | pmid:15083191 |
Reitsamer R et al. | 200 Sentinel lymph node biopsies without axillary lymph node dissection -- no axillary recurrences after a 3-year follow-up. | 2004 | Br. J. Cancer | pmid:15083184 |
Weigelt B et al. | Detection of metastases in sentinel lymph nodes of breast cancer patients by multiple mRNA markers. | 2004 | Br. J. Cancer | pmid:15083181 |
Olivier RI et al. | Clinical outcome of prophylactic oophorectomy in BRCA1/BRCA2 mutation carriers and events during follow-up. | 2004 | Br. J. Cancer | pmid:15083174 |
Beskow C et al. | Radioresistant cervical cancer shows upregulation of the NHEJ proteins DNA-PKcs, Ku70 and Ku86. | 2009 | Br. J. Cancer | pmid:19672258 |
Preuss SF et al. | Nuclear survivin expression is associated with HPV-independent carcinogenesis and is an indicator of poor prognosis in oropharyngeal cancer. | 2008 | Br. J. Cancer | pmid:18212752 |
Otake M et al. | Selective accumulation of ALA-induced PpIX and photodynamic effect in chemically induced hepatocellular carcinoma. | 2003 | Br. J. Cancer | pmid:12915887 |
Bradley G et al. | Abnormal DNA content in oral epithelial dysplasia is associated with increased risk of progression to carcinoma. | 2010 | Br. J. Cancer | pmid:20859287 |
Page K et al. | Detection of HER2 amplification in circulating free DNA in patients with breast cancer. | 2011 | Br. J. Cancer | pmid:21427727 |
Duanmu J et al. | Effective treatment of chemoresistant breast cancer in vitro and in vivo by a factor VII-targeted photodynamic therapy. | 2011 | Br. J. Cancer | pmid:21427724 |
Bruynzeel AM et al. | Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice. | 2007 | Br. J. Cancer | pmid:17325706 |
Bluff JE et al. | Angiogenesis is associated with the onset of hyperplasia in human ductal breast disease. | 2009 | Br. J. Cancer | pmid:19623180 |
Mellor HR et al. | A model of quiescent tumour microregions for evaluating multicellular resistance to chemotherapeutic drugs. | 2005 | Br. J. Cancer | pmid:16052217 |
Shaw RJ et al. | Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer. | 2009 | Br. J. Cancer | pmid:19568272 |
Zheng HC et al. | Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis. | 2006 | Br. J. Cancer | pmid:17088917 |
Deans DA et al. | Elevated tumour interleukin-1beta is associated with systemic inflammation: A marker of reduced survival in gastro-oesophageal cancer. | 2006 | Br. J. Cancer | pmid:17088911 |
Sheach LA et al. | Androgen-related expression of G-proteins in ovarian cancer. | 2009 | Br. J. Cancer | pmid:19623182 |
El-Emir E et al. | Characterisation and radioimmunotherapy of L19-SIP, an anti-angiogenic antibody against the extra domain B of fibronectin, in colorectal tumour models. | 2007 | Br. J. Cancer | pmid:17519905 |
Negishi T et al. | NK105, a paclitaxel-incorporating micellar nanoparticle, is a more potent radiosensitising agent compared to free paclitaxel. | 2006 | Br. J. Cancer | pmid:16909136 |
Donnelly ET et al. | Metallothionein crypt-restricted immunopositivity indices (MTCRII) correlate with aberrant crypt foci (ACF) in mouse colon. | 2005 | Br. J. Cancer | pmid:15928667 |
Ord JJ et al. | Phase I trial of intravesical Suramin in recurrent superficial transitional cell bladder carcinoma. | 2005 | Br. J. Cancer | pmid:15928663 |
Debergh I et al. | The low-molecular-weight heparin, nadroparin, inhibits tumour angiogenesis in a rodent dorsal skinfold chamber model. | 2010 | Br. J. Cancer | pmid:20125158 |
Milde-Langosch K et al. | Expression and prognostic relevance of activated extracellular-regulated kinases (ERK1/2) in breast cancer. | 2005 | Br. J. Cancer | pmid:15928662 |
Vlahovic G et al. | Treatment with Imatinib in NSCLC is associated with decrease of phosphorylated PDGFR-beta and VEGF expression, decrease in interstitial fluid pressure and improvement of oxygenation. | 2006 | Br. J. Cancer | pmid:17003785 |
Ma S et al. | O6-methylguanine-DNA-methyltransferase expression and gene polymorphisms in relation to chemotherapeutic response in metastatic melanoma. | 2003 | Br. J. Cancer | pmid:14562026 |
Debrock G et al. | A phase II trial with rosiglitazone in liposarcoma patients. | 2003 | Br. J. Cancer | pmid:14562008 |
Sarbia M et al. | The predictive value of molecular markers (p53, EGFR, ATM, CHK2) in multimodally treated squamous cell carcinoma of the oesophagus. | 2007 | Br. J. Cancer | pmid:17940507 |
Lujan B et al. | Activation of the EGFR/ERK pathway in high-grade mucoepidermoid carcinomas of the salivary glands. | 2010 | Br. J. Cancer | pmid:20664595 |
Dufresne A et al. | Identification of biological factors predictive of response to imatinib mesylate in aggressive fibromatosis. | 2010 | Br. J. Cancer | pmid:20664593 |
Brown MD et al. | Promotion of prostatic metastatic migration towards human bone marrow stoma by Omega 6 and its inhibition by Omega 3 PUFAs. | 2006 | Br. J. Cancer | pmid:16523199 |
Lau ST et al. | Role of reactive oxygen species in brucein D-mediated p38-mitogen-activated protein kinase and nuclear factor-kappaB signalling pathways in human pancreatic adenocarcinoma cells. | 2010 | Br. J. Cancer | pmid:20068565 |
Cellai I et al. | In vivo effects of rosiglitazone in a human neuroblastoma xenograft. | 2010 | Br. J. Cancer | pmid:20068562 |
Mori N et al. | Expression of HER-2 affects patient survival and paclitaxel sensitivity in endometrial cancer. | 2010 | Br. J. Cancer | pmid:20664599 |
Weng WH et al. | Gain of 17q in malignant fibrous histiocytoma is associated with a longer disease-free survival and a low risk of developing distant metastasis. | 2003 | Br. J. Cancer | pmid:12915885 |
Nosho K et al. | Gene expression profiling of colorectal adenomas and early invasive carcinomas by cDNA array analysis. | 2005 | Br. J. Cancer | pmid:15785755 |
Matsumoto N et al. | Possible alternative carcinogenesis pathway featuring microsatellite instability in colorectal cancer stroma. | 2003 | Br. J. Cancer | pmid:12915883 |
Ajisaka H and Miwa K | Micrometastases in sentinel nodes of gastric cancer. | 2003 | Br. J. Cancer | pmid:12915877 |
MacGrogan G et al. | DNA topoisomerase IIalpha expression and the response toprimary chemotherapy in breast cancer. | 2003 | Br. J. Cancer | pmid:12915875 |
Bach SP et al. | Regional localisation of p53-independent apoptosis determines toxicity to 5-fluorouracil and pyrrolidinedithiocarbamate in the murine gut. | 2006 | Br. J. Cancer | pmid:16804527 |
Jekimovs CR et al. | Low frequency of CHEK2 1100delC allele in Australian multiple-case breast cancer families: functional analysis in heterozygous individuals. | 2005 | Br. J. Cancer | pmid:15700044 |
te Velde EA et al. | Early endostatin treatment inhibits metastatic seeding of murine colorectal cancer cells in the liver and their adhesion to endothelial cells. | 2005 | Br. J. Cancer | pmid:15700042 |
Blancato J et al. | Correlation of amplification and overexpression of the c-myc oncogene in high-grade breast cancer: FISH, in situ hybridisation and immunohistochemical analyses. | 2004 | Br. J. Cancer | pmid:15083194 |
Roka F et al. | Sentinel node status in melanoma patients is not predictive for overall survival upon multivariate analysis. | 2005 | Br. J. Cancer | pmid:15700039 |
Gerber SA et al. | Mechanism of IL-12 mediated alterations in tumour blood vessel morphology: analysis using whole-tissue mounts. | 2003 | Br. J. Cancer | pmid:12778077 |
Wagenaar-Miller RA et al. | Cooperative effects of matrix metalloproteinase and cyclooxygenase-2 inhibition on intestinal adenoma reduction. | 2003 | Br. J. Cancer | pmid:12778076 |
Tonetti DA et al. | Elevated protein kinase C alpha expression may be predictive of tamoxifen treatment failure. | 2003 | Br. J. Cancer | pmid:12778068 |
Gisselsson D et al. | Centrosomal abnormalities, multipolar mitoses, and chromosomal instability in head and neck tumours with dysfunctional telomeres. | 2002 | Br. J. Cancer | pmid:12107843 |
Attard G et al. | Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer. | 2008 | Br. J. Cancer | pmid:18594527 |
Subramaniam V et al. | The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase. | 2003 | Br. J. Cancer | pmid:14562029 |
Nomura S et al. | FGF10/FGFR2 signal induces cell migration and invasion in pancreatic cancer. | 2008 | Br. J. Cancer | pmid:18594526 |