HEMATOXYLIN is a lipid of Polyketides (PK) class. Hematoxylin is associated with abnormalities such as Eosinophilia, Duodenal Adenoma, Senile Plaques, Morphologically altered structure and Cervical abscess. The involved functions are known as Uptake, Apoptosis, Amplification, Necrosis and Karyopyknosis. Hematoxylin often locates in Body tissue, Extracellular, Compact bone, Skin and Basement membrane. The associated genes with HEMATOXYLIN are GAPDH gene, Genome, Elastin, MERTK wt Allele and P4HTM gene.
To understand associated biological information of HEMATOXYLIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
HEMATOXYLIN is suspected in Senile Plaques, Eosinophilia, Duodenal Adenoma, Morphologically altered structure, Cervical abscess and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with HEMATOXYLIN
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lu F et al. | Nuclear ING2 expression is reduced in human cutaneous melanomas. | 2006 | Br. J. Cancer | pmid:16755297 |
GarcÃa-Closas M et al. | Established breast cancer risk factors by clinically important tumour characteristics. | 2006 | Br. J. Cancer | pmid:16755295 |
Bradley G et al. | The expression of p53-induced protein with death domain (Pidd) and apoptosis in oral squamous cell carcinoma. | 2007 | Br. J. Cancer | pmid:17437012 |
Hsieh JL et al. | Gene therapy for bladder cancer using E1B-55 kD-deleted adenovirus in combination with adenoviral vector encoding plasminogen kringles 1-5. | 2003 | Br. J. Cancer | pmid:12778082 |
Nieto Y et al. | Prognostic analysis of tumour angiogenesis, determined by microvessel density and expression of vascular endothelial growth factor, in high-risk primary breast cancer patients treated with high-dose chemotherapy. | 2007 | Br. J. Cancer | pmid:17609662 |
Terry G et al. | The role of human papillomavirus type 16 and the fragile histidine triad gene in the outcome of cervical neoplastic lesions. | 2004 | Br. J. Cancer | pmid:15570308 |
Zaman MS et al. | The functional significance of microRNA-145 in prostate cancer. | 2010 | Br. J. Cancer | pmid:20588276 |
Hu DE et al. | Early detection of tumour immune-rejection using magnetic resonance imaging. | 2003 | Br. J. Cancer | pmid:12671716 |
Watson PH et al. | Carbonic anhydrase XII is a marker of good prognosis in invasive breast carcinoma. | 2003 | Br. J. Cancer | pmid:12671706 |
Mekenkamp LJ et al. | Clinicopathological features and outcome in advanced colorectal cancer patients with synchronous vs metachronous metastases. | 2010 | Br. J. Cancer | pmid:20551951 |
Unger K et al. | RET rearrangements in post-Chernobyl papillary thyroid carcinomas with a short latency analysed by interphase FISH. | 2006 | Br. J. Cancer | pmid:16641909 |
Shetty G et al. | Raman spectroscopy: elucidation of biochemical changes in carcinogenesis of oesophagus. | 2006 | Br. J. Cancer | pmid:16622450 |
Hanly AM et al. | Thrombomodulin expression in colorectal carcinoma is protective and correlates with survival. | 2006 | Br. J. Cancer | pmid:16622452 |
Scott IS et al. | A minimally invasive immunocytochemical approach to early detection of oral squamous cell carcinoma and dysplasia. | 2006 | Br. J. Cancer | pmid:16622441 |
Liu J et al. | Adenovirus-mediated hypoxia-targeting cytosine deaminase gene therapy enhances radiotherapy in tumour xenografts. | 2007 | Br. J. Cancer | pmid:17519901 |
Suzuki S et al. | MAGE-A protein and MAGE-A10 gene expressions in liver metastasis in patients with stomach cancer. | 2008 | Br. J. Cancer | pmid:18594524 |
Grabowski P et al. | Prognostic value of nuclear survivin expression in oesophageal squamous cell carcinoma. | 2003 | Br. J. Cancer | pmid:12556969 |
Nam SY et al. | A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis. | 2011 | Br. J. Cancer | pmid:21119667 |
Lamont FR et al. | Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo. | 2011 | Br. J. Cancer | pmid:21119661 |
Batistatou A et al. | In breast carcinoma dysadherin expression is correlated with invasiveness but not with E-cadherin. | 2007 | Br. J. Cancer | pmid:17437014 |
Griffiths EA et al. | Increasing expression of hypoxia-inducible proteins in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence. | 2007 | Br. J. Cancer | pmid:17437013 |
Barker SE et al. | Immunotherapy for neuroblastoma using syngeneic fibroblasts transfected with IL-2 and IL-12. | 2007 | Br. J. Cancer | pmid:17595664 |
Rehman I et al. | S100A6 (Calcyclin) is a prostate basal cell marker absent in prostate cancer and its precursors. | 2004 | Br. J. Cancer | pmid:15280928 |
McFadyen MC et al. | Cytochrome P450 CYP1B1 activity in renal cell carcinoma. | 2004 | Br. J. Cancer | pmid:15280921 |
Pritchard-Jones RO et al. | Expression of VEGF(xxx)b, the inhibitory isoforms of VEGF, in malignant melanoma. | 2007 | Br. J. Cancer | pmid:17595666 |
Connolly EM et al. | Cyclo-oxygenase inhibition reduces tumour growth and metastasis in an orthotopic model of breast cancer. | 2002 | Br. J. Cancer | pmid:12107848 |
Barnes N et al. | Survivin expression in in situ and invasive breast cancer relates to COX-2 expression and DCIS recurrence. | 2006 | Br. J. Cancer | pmid:16421596 |
Le Page C et al. | Gene expression profiling of primary cultures of ovarian epithelial cells identifies novel molecular classifiers of ovarian cancer. | 2006 | Br. J. Cancer | pmid:16421595 |
Hiraoka K et al. | Concurrent infiltration by CD8+ T cells and CD4+ T cells is a favourable prognostic factor in non-small-cell lung carcinoma. | 2006 | Br. J. Cancer | pmid:16421594 |
Querzoli P et al. | An immunohistochemically positive E-cadherin status is not always predictive for a good prognosis in human breast cancer. | 2010 | Br. J. Cancer | pmid:21063415 |
Lawson MH et al. | Bcl-2 and β1-integrin predict survival in a tissue microarray of small cell lung cancer. | 2010 | Br. J. Cancer | pmid:21063403 |
Kazama S et al. | Tumour budding at the deepest invasive margin correlates with lymph node metastasis in submucosal colorectal cancer detected by anticytokeratin antibody CAM5.2. | 2006 | Br. J. Cancer | pmid:16404429 |
Zheng BY et al. | Detection of adeno-associated virus type 2 genome in cervical carcinoma. | 2006 | Br. J. Cancer | pmid:16736006 |
Ebihara Y et al. | DARPP-32 expression arises after a phase of dysplasia in oesophageal squamous cell carcinoma. | 2004 | Br. J. Cancer | pmid:15188007 |
Julien C et al. | Assessment of vascular reactivity in rat brain glioma by measuring regional blood volume during graded hypoxic hypoxia. | 2004 | Br. J. Cancer | pmid:15188003 |
Belien JA et al. | Gross genomic damage measured by DNA image cytometry independently predicts gastric cancer patient survival. | 2009 | Br. J. Cancer | pmid:19738619 |
Qualtrough D et al. | The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro. | 2009 | Br. J. Cancer | pmid:19738613 |
Sigstad E et al. | A prospective study of the relationship between prediagnostic human papillomavirus seropositivity and HPV DNA in subsequent cervical carcinomas. | 2002 | Br. J. Cancer | pmid:12107839 |
Griffiths EA et al. | Hypoxia-associated markers in gastric carcinogenesis and HIF-2alpha in gastric and gastro-oesophageal cancer prognosis. | 2008 | Br. J. Cancer | pmid:18283323 |
Campbell L et al. | Combined expression of caveolin-1 and an activated AKT/mTOR pathway predicts reduced disease-free survival in clinically confined renal cell carcinoma. | 2008 | Br. J. Cancer | pmid:18283322 |
Lin HJ et al. | Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer. | 2005 | Br. J. Cancer | pmid:16288304 |
Hong AM et al. | Human papillomavirus predicts outcome in oropharyngeal cancer in patients treated primarily with surgery or radiation therapy. | 2010 | Br. J. Cancer | pmid:20959828 |
Tørring N et al. | Genome-wide analysis of allelic imbalance in prostate cancer using the Affymetrix 50K SNP mapping array. | 2007 | Br. J. Cancer | pmid:17245344 |
Yun JP et al. | Increased expression of nucleophosmin/B23 in hepatocellular carcinoma and correlation with clinicopathological parameters. | 2007 | Br. J. Cancer | pmid:17245342 |
Yokoyama Y and Ramakrishnan S | Improved biological activity of a mutant endostatin containing a single amino-acid substitution. | 2004 | Br. J. Cancer | pmid:15083196 |
Sasiadek MM et al. | Impairment of MLH1 and CDKN2A in oncogenesis of laryngeal cancer. | 2004 | Br. J. Cancer | pmid:15083191 |
Frei KA et al. | Photodynamic detection of diseased axillary sentinel lymph node after oral application of aminolevulinic acid in patients with breast cancer. | 2004 | Br. J. Cancer | pmid:14970857 |
Reitsamer R et al. | 200 Sentinel lymph node biopsies without axillary lymph node dissection -- no axillary recurrences after a 3-year follow-up. | 2004 | Br. J. Cancer | pmid:15083184 |
Grelier G et al. | Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype. | 2009 | Br. J. Cancer | pmid:19672267 |
Boneberg EM et al. | Angiogenesis and lymphangiogenesis are downregulated in primary breast cancer. | 2009 | Br. J. Cancer | pmid:19672262 |
Beskow C et al. | Radioresistant cervical cancer shows upregulation of the NHEJ proteins DNA-PKcs, Ku70 and Ku86. | 2009 | Br. J. Cancer | pmid:19672258 |
Buffart TE et al. | MAL promoter hypermethylation as a novel prognostic marker in gastric cancer. | 2008 | Br. J. Cancer | pmid:19002170 |
Knight JF et al. | TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer. | 2008 | Br. J. Cancer | pmid:19002168 |
Otake M et al. | Selective accumulation of ALA-induced PpIX and photodynamic effect in chemically induced hepatocellular carcinoma. | 2003 | Br. J. Cancer | pmid:12915887 |
Bradley G et al. | Abnormal DNA content in oral epithelial dysplasia is associated with increased risk of progression to carcinoma. | 2010 | Br. J. Cancer | pmid:20859287 |
Griffiths RW et al. | Expression of the 5T4 oncofoetal antigen in renal cell carcinoma: a potential target for T-cell-based immunotherapy. | 2005 | Br. J. Cancer | pmid:16222313 |
Koppert LB et al. | Frequent loss of the AXIN1 locus but absence of AXIN1 gene mutations in adenocarcinomas of the gastro-oesophageal junction with nuclear beta-catenin expression. | 2004 | Br. J. Cancer | pmid:14970870 |
Bruynzeel AM et al. | Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice. | 2007 | Br. J. Cancer | pmid:17325706 |
Al-Saad S et al. | The prognostic impact of NF-kappaB p105, vimentin, E-cadherin and Par6 expression in epithelial and stromal compartment in non-small-cell lung cancer. | 2008 | Br. J. Cancer | pmid:18854838 |
McCall P et al. | Is PTEN loss associated with clinical outcome measures in human prostate cancer? | 2008 | Br. J. Cancer | pmid:18854827 |
Brunstein F et al. | Histamine, a vasoactive agent with vascular disrupting potential, improves tumour response by enhancing local drug delivery. | 2006 | Br. J. Cancer | pmid:17106443 |
Ord JJ et al. | Comparison of hypoxia transcriptome in vitro with in vivo gene expression in human bladder cancer. | 2005 | Br. J. Cancer | pmid:16052224 |
Mellor HR et al. | A model of quiescent tumour microregions for evaluating multicellular resistance to chemotherapeutic drugs. | 2005 | Br. J. Cancer | pmid:16052217 |
Leonard P et al. | Gene expression array profile of human osteosarcoma. | 2003 | Br. J. Cancer | pmid:14676807 |
Lo Muzio L et al. | Survivin expression in oral squamous cell carcinoma. | 2003 | Br. J. Cancer | pmid:14676801 |
Wu F et al. | A randomised clinical trial of high-intensity focused ultrasound ablation for the treatment of patients with localised breast cancer. | 2003 | Br. J. Cancer | pmid:14676799 |
Shaw RJ et al. | Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer. | 2009 | Br. J. Cancer | pmid:19568272 |
Charalambous MP et al. | Expression of COX-2, NF-kappaB-p65, NF-kappaB-p50 and IKKalpha in malignant and adjacent normal human colorectal tissue. | 2009 | Br. J. Cancer | pmid:19513071 |
El-Emir E et al. | Characterisation and radioimmunotherapy of L19-SIP, an anti-angiogenic antibody against the extra domain B of fibronectin, in colorectal tumour models. | 2007 | Br. J. Cancer | pmid:17519905 |
Matsubara J et al. | Impacts of excision repair cross-complementing gene 1 (ERCC1), dihydropyrimidine dehydrogenase, and epidermal growth factor receptor on the outcomes of patients with advanced gastric cancer. | 2008 | Br. J. Cancer | pmid:18231104 |
Tonini G et al. | Nuclear and cytoplasmic expression of survivin in 67 surgically resected pancreatic cancer patients. | 2005 | Br. J. Cancer | pmid:15928668 |
Donnelly ET et al. | Metallothionein crypt-restricted immunopositivity indices (MTCRII) correlate with aberrant crypt foci (ACF) in mouse colon. | 2005 | Br. J. Cancer | pmid:15928667 |
Ord JJ et al. | Phase I trial of intravesical Suramin in recurrent superficial transitional cell bladder carcinoma. | 2005 | Br. J. Cancer | pmid:15928663 |
Radny P et al. | Phase II trial of intralesional therapy with interleukin-2 in soft-tissue melanoma metastases. | 2003 | Br. J. Cancer | pmid:14583759 |
Ma S et al. | O6-methylguanine-DNA-methyltransferase expression and gene polymorphisms in relation to chemotherapeutic response in metastatic melanoma. | 2003 | Br. J. Cancer | pmid:14562026 |
Debrock G et al. | A phase II trial with rosiglitazone in liposarcoma patients. | 2003 | Br. J. Cancer | pmid:14562008 |
Brown MD et al. | Promotion of prostatic metastatic migration towards human bone marrow stoma by Omega 6 and its inhibition by Omega 3 PUFAs. | 2006 | Br. J. Cancer | pmid:16523199 |
Liu W et al. | Effects of overexpression of ephrin-B2 on tumour growth in human colorectal cancer. | 2004 | Br. J. Cancer | pmid:15083195 |
Bugat R et al. | Summary of the Standards, Options and Recommendations for the management of patients with carcinoma of unknown primary site (2002). | 2003 | Br. J. Cancer | pmid:12915904 |
Mori N et al. | Expression of HER-2 affects patient survival and paclitaxel sensitivity in endometrial cancer. | 2010 | Br. J. Cancer | pmid:20664599 |
Villers A et al. | Summary of the Standards, Options and Recommendations for the management of patients with nonmetastatic prostate cancer (2001). | 2003 | Br. J. Cancer | pmid:12915903 |
Weng WH et al. | Gain of 17q in malignant fibrous histiocytoma is associated with a longer disease-free survival and a low risk of developing distant metastasis. | 2003 | Br. J. Cancer | pmid:12915885 |
Polterauer S et al. | The impact of lymph node density on survival of cervical cancer patients. | 2010 | Br. J. Cancer | pmid:20628380 |
Caldwell GM et al. | Wnt signalling in adenomas of familial adenomatous polyposis patients. | 2010 | Br. J. Cancer | pmid:20628379 |
Yoshino H et al. | The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. | 2011 | Br. J. Cancer | pmid:21304530 |
Schimanski CC et al. | Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4. | 2006 | Br. J. Cancer | pmid:16819541 |
Van Laere SJ et al. | NF-kappaB activation in inflammatory breast cancer is associated with oestrogen receptor downregulation, secondary to EGFR and/or ErbB2 overexpression and MAPK hyperactivation. | 2007 | Br. J. Cancer | pmid:17700572 |
Bach SP et al. | Regional localisation of p53-independent apoptosis determines toxicity to 5-fluorouracil and pyrrolidinedithiocarbamate in the murine gut. | 2006 | Br. J. Cancer | pmid:16804527 |
Kato T et al. | The combination of angiogenesis and blood vessel invasion as a prognostic indicator in primary breast cancer. | 2003 | Br. J. Cancer | pmid:12799634 |
Yoshimoto M et al. | FISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome. | 2007 | Br. J. Cancer | pmid:17700571 |
Jekimovs CR et al. | Low frequency of CHEK2 1100delC allele in Australian multiple-case breast cancer families: functional analysis in heterozygous individuals. | 2005 | Br. J. Cancer | pmid:15700044 |
te Velde EA et al. | Early endostatin treatment inhibits metastatic seeding of murine colorectal cancer cells in the liver and their adhesion to endothelial cells. | 2005 | Br. J. Cancer | pmid:15700042 |
Blancato J et al. | Correlation of amplification and overexpression of the c-myc oncogene in high-grade breast cancer: FISH, in situ hybridisation and immunohistochemical analyses. | 2004 | Br. J. Cancer | pmid:15083194 |
Gerber SA et al. | Mechanism of IL-12 mediated alterations in tumour blood vessel morphology: analysis using whole-tissue mounts. | 2003 | Br. J. Cancer | pmid:12778077 |
Arrieta O et al. | Expression of AT1 and AT2 angiotensin receptors in astrocytomas is associated with poor prognosis. | 2008 | Br. J. Cancer | pmid:18594540 |
Koivunen JP et al. | Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients. | 2008 | Br. J. Cancer | pmid:18594528 |
Gisselsson D et al. | Centrosomal abnormalities, multipolar mitoses, and chromosomal instability in head and neck tumours with dysfunctional telomeres. | 2002 | Br. J. Cancer | pmid:12107843 |
Attard G et al. | Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer. | 2008 | Br. J. Cancer | pmid:18594527 |
Subramaniam V et al. | The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase. | 2003 | Br. J. Cancer | pmid:14562029 |
Nomura S et al. | FGF10/FGFR2 signal induces cell migration and invasion in pancreatic cancer. | 2008 | Br. J. Cancer | pmid:18594526 |