HEMATOXYLIN is a lipid of Polyketides (PK) class. Hematoxylin is associated with abnormalities such as Eosinophilia, Duodenal Adenoma, Senile Plaques, Morphologically altered structure and Cervical abscess. The involved functions are known as Uptake, Apoptosis, Amplification, Necrosis and Karyopyknosis. Hematoxylin often locates in Body tissue, Extracellular, Compact bone, Skin and Basement membrane. The associated genes with HEMATOXYLIN are GAPDH gene, Genome, Elastin, MERTK wt Allele and P4HTM gene.
To understand associated biological information of HEMATOXYLIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
HEMATOXYLIN is suspected in Senile Plaques, Eosinophilia, Duodenal Adenoma, Morphologically altered structure, Cervical abscess and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with HEMATOXYLIN
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Townsley CA et al. | Phase II study of erlotinib (OSI-774) in patients with metastatic colorectal cancer. | 2006 | Br. J. Cancer | pmid:16570047 |
Kronqvist P et al. | Morphometrical malignancy grading is a valuable prognostic factor in invasive ductal breast cancer. | 2002 | Br. J. Cancer | pmid:12439717 |
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Onda T et al. | Ubiquitous mitochondrial creatine kinase downregulated in oral squamous cell carcinoma. | 2006 | Br. J. Cancer | pmid:16479256 |
Wang Y et al. | Tissue microarray analysis of human FRAT1 expression and its correlation with the subcellular localisation of beta-catenin in ovarian tumours. | 2006 | Br. J. Cancer | pmid:16479254 |
Anders M et al. | Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression. | 2009 | Br. J. Cancer | pmid:19142187 |
Wu X et al. | Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin. | 2009 | Br. J. Cancer | pmid:19142186 |
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D'Arcy V et al. | BORIS, a paralogue of the transcription factor, CTCF, is aberrantly expressed in breast tumours. | 2008 | Br. J. Cancer | pmid:18195709 |
Graf MR et al. | The neuro-steroid, 3beta androstene 17alpha diol exhibits potent cytotoxic effects on human malignant glioma and lymphoma cells through different programmed cell death pathways. | 2007 | Br. J. Cancer | pmid:17637679 |
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Barnes NL et al. | Cyclooxygenase-2 inhibition: effects on tumour growth, cell cycling and lymphangiogenesis in a xenograft model of breast cancer. | 2007 | Br. J. Cancer | pmid:17285134 |
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Wang W et al. | Genomic analysis reveals RhoC as a potential marker in hepatocellular carcinoma with poor prognosis. | 2004 | Br. J. Cancer | pmid:15150600 |
Carlsson J et al. | HER2 expression in breast cancer primary tumours and corresponding metastases. Original data and literature review. | 2004 | Br. J. Cancer | pmid:15150568 |
Hekmatyar SK et al. | ¹H nuclear magnetic resonance spectroscopy characterisation of metabolic phenotypes in the medulloblastoma of the SMO transgenic mice. | 2010 | Br. J. Cancer | pmid:20842126 |
Barboro P et al. | Heterogeneous nuclear ribonucleoprotein K: altered pattern of expression associated with diagnosis and prognosis of prostate cancer. | 2009 | Br. J. Cancer | pmid:19401687 |
Nakayama N et al. | KRAS or BRAF mutation status is a useful predictor of sensitivity to MEK inhibition in ovarian cancer. | 2008 | Br. J. Cancer | pmid:19018267 |
van Etten B et al. | Prerequisites for effective adenovirus mediated gene therapy of colorectal liver metastases in the rat using an intracellular neutralizing antibody fragment to p21-Ras. | 2002 | Br. J. Cancer | pmid:11875712 |
Kato T et al. | Prognostic significance of microvessel density and other variables in Japanese and British patients with primary invasive breast cancer. | 2007 | Br. J. Cancer | pmid:17923874 |
Kuefer R et al. | Sodium butyrate and tributyrin induce in vivo growth inhibition and apoptosis in human prostate cancer. | 2004 | Br. J. Cancer | pmid:14735205 |
Bing C et al. | Expression of uncoupling proteins-1, -2 and -3 mRNA is induced by an adenocarcinoma-derived lipid-mobilizing factor. | 2002 | Br. J. Cancer | pmid:11870545 |
Dales JP et al. | Prediction of metastasis risk (11 year follow-up) using VEGF-R1, VEGF-R2, Tie-2/Tek and CD105 expression in breast cancer (n=905). | 2004 | Br. J. Cancer | pmid:15026804 |
Nakayama K et al. | Allelic loss at 19q12 and Xq11-12 predict an adverse clinical outcome in patients with mucinous ovarian tumours of low malignant potential. | 2004 | Br. J. Cancer | pmid:15026802 |
Lee KT et al. | Overexpression of Id-1 is significantly associated with tumour angiogenesis in human pancreas cancers. | 2004 | Br. J. Cancer | pmid:15026801 |
Teh SK et al. | Diagnostic potential of near-infrared Raman spectroscopy in the stomach: differentiating dysplasia from normal tissue. | 2008 | Br. J. Cancer | pmid:18195711 |
Millis RR et al. | Occult axillary lymph node metastases are of no prognostic significance in breast cancer. | 2002 | Br. J. Cancer | pmid:11875706 |
Fontanini G et al. | A high vascular count and overexpression of vascular endothelial growth factor are associated with unfavourable prognosis in operated small cell lung carcinoma. | 2002 | Br. J. Cancer | pmid:11870537 |
Davidson EJ et al. | Minichromosome maintenance (Mcm) proteins, cyclin B1 and D1, phosphohistone H3 and in situ DNA replication for functional analysis of vulval intraepithelial neoplasia. | 2003 | Br. J. Cancer | pmid:12610511 |
Rosenthal AN et al. | Immunohistochemical analysis of p53 in vulval intraepithelial neoplasia and vulval squamous cell carcinoma. | 2003 | Br. J. Cancer | pmid:12610510 |
Terry G et al. | Abnormal FHIT expression profiles in cervical intraepithelial neoplastic (CIN) lesions. | 2002 | Br. J. Cancer | pmid:11875703 |
Cai H et al. | Growth-inhibitory and cell cycle-arresting properties of the rice bran constituent tricin in human-derived breast cancer cells in vitro and in nude mice in vivo. | 2004 | Br. J. Cancer | pmid:15316567 |
Hall JS et al. | Exon-array profiling unlocks clinically and biologically relevant gene signatures from formalin-fixed paraffin-embedded tumour samples. | 2011 | Br. J. Cancer | pmid:21407225 |
Bing C et al. | Adipose atrophy in cancer cachexia: morphologic and molecular analysis of adipose tissue in tumour-bearing mice. | 2006 | Br. J. Cancer | pmid:17047651 |
Frost K et al. | Inhibin/activin expression in human and rodent liver: subunits α and βB as new players in human hepatocellular carcinoma? | 2011 | Br. J. Cancer | pmid:21407220 |
Hao J et al. | Co-expression of CD147 (EMMPRIN), CD44v3-10, MDR1 and monocarboxylate transporters is associated with prostate cancer drug resistance and progression. | 2010 | Br. J. Cancer | pmid:20736947 |
Graham K et al. | Gene expression in histologically normal epithelium from breast cancer patients and from cancer-free prophylactic mastectomy patients shares a similar profile. | 2010 | Br. J. Cancer | pmid:20197764 |
Hori K and Saito S | Induction of tumour blood flow stasis and necrosis: a new function for epinephrine similar to that of combretastatin A-4 derivative AVE8062 (AC7700). | 2004 | Br. J. Cancer | pmid:14735207 |
Hofer MD et al. | Expression of MTA1 promotes motility and invasiveness of PANC-1 pancreatic carcinoma cells. | 2004 | Br. J. Cancer | pmid:14735193 |
Ash S et al. | Immunomodulation with dendritic cells and donor lymphocyte infusion converge to induce graft vs neuroblastoma reactions without GVHD after allogeneic bone marrow transplantation. | 2010 | Br. J. Cancer | pmid:20978501 |
Terry G et al. | The expression of FHIT, PCNA and EGFR in benign and malignant breast lesions. | 2007 | Br. J. Cancer | pmid:17164758 |
Hernes E et al. | Expression of the epidermal growth factor receptor family in prostate carcinoma before and during androgen-independence. | 2004 | Br. J. Cancer | pmid:14735192 |
Gu C et al. | Low expression of polypeptide GalNAc N-acetylgalactosaminyl transferase-3 in lung adenocarcinoma: impact on poor prognosis and early recurrence. | 2004 | Br. J. Cancer | pmid:14735190 |
Kahlert C et al. | Increased expression of ALCAM/CD166 in pancreatic cancer is an independent prognostic marker for poor survival and early tumour relapse. | 2009 | Br. J. Cancer | pmid:19603023 |
Beresford MJ et al. | The relationship of the neo-angiogenic marker, endoglin, with response to neoadjuvant chemotherapy in breast cancer. | 2006 | Br. J. Cancer | pmid:17160082 |
Lee YK et al. | BubR1 as a prognostic marker for recurrence-free survival rates in epithelial ovarian cancers. | 2009 | Br. J. Cancer | pmid:19603021 |
Chen H et al. | Coexpression of invasive markers (uPA, CD44) and multiple drug-resistance proteins (MDR1, MRP2) is correlated with epithelial ovarian cancer progression. | 2009 | Br. J. Cancer | pmid:19603017 |
Yoshikawa D et al. | Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma. | 2008 | Br. J. Cancer | pmid:18087285 |
Negri FV et al. | Biological predictive factors in rectal cancer treated with preoperative radiotherapy or radiochemotherapy. | 2008 | Br. J. Cancer | pmid:18087284 |
Savic S et al. | Comprehensive epidermal growth factor receptor gene analysis from cytological specimens of non-small-cell lung cancers. | 2008 | Br. J. Cancer | pmid:18087280 |
Mizukami Y et al. | Localisation pattern of Foxp3+ regulatory T cells is associated with clinical behaviour in gastric cancer. | 2008 | Br. J. Cancer | pmid:18087278 |
Escaff S et al. | Study of matrix metalloproteinases and their inhibitors in prostate cancer. | 2010 | Br. J. Cancer | pmid:20160732 |
Hassel JC et al. | MGMT gene promoter methylation correlates with tolerance of temozolomide treatment in melanoma but not with clinical outcome. | 2010 | Br. J. Cancer | pmid:20736948 |
Myers E et al. | A positive role for PEA3 in HER2-mediated breast tumour progression. | 2006 | Br. J. Cancer | pmid:17060941 |
Dunn J et al. | Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy. | 2009 | Br. J. Cancer | pmid:19536096 |
Siriwardena BS et al. | Periostin is frequently overexpressed and enhances invasion and angiogenesis in oral cancer. | 2006 | Br. J. Cancer | pmid:17060937 |
Lee JW et al. | BRAF mutations in non-Hodgkin's lymphoma. | 2003 | Br. J. Cancer | pmid:14612909 |
Alain T et al. | The oncolytic effect in vivo of reovirus on tumour cells that have survived reovirus cell killing in vitro. | 2006 | Br. J. Cancer | pmid:17047650 |
Oehler MK et al. | Tissue and plasma expression of the angiogenic peptide adrenomedullin in breast cancer. | 2003 | Br. J. Cancer | pmid:14612905 |
Campbell L et al. | Caveolin-1 overexpression predicts poor disease-free survival of patients with clinically confined renal cell carcinoma. | 2003 | Br. J. Cancer | pmid:14612902 |
Bromwich EJ et al. | The relationship between T-lymphocyte infiltration, stage, tumour grade and survival in patients undergoing curative surgery for renal cell cancer. | 2003 | Br. J. Cancer | pmid:14612901 |
Kawaraya M et al. | Evaluation of various cytological examinations by bronchoscopy in the diagnosis of peripheral lung cancer. | 2003 | Br. J. Cancer | pmid:14612897 |
Kohno Y et al. | Expression of Y-box-binding protein dbpC/contrin, a potentially new cancer/testis antigen. | 2006 | Br. J. Cancer | pmid:16479255 |
Reid AH et al. | Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer. | 2010 | Br. J. Cancer | pmid:20104229 |
Taylor SE et al. | Infrared spectroscopy with multivariate analysis to interrogate endometrial tissue: a novel and objective diagnostic approach. | 2011 | Br. J. Cancer | pmid:21326237 |
Shimada K et al. | Aberrant expression of RAB1A in human tongue cancer. | 2005 | Br. J. Cancer | pmid:15870709 |
Almstrup K et al. | Genome-wide gene expression profiling of testicular carcinoma in situ progression into overt tumours. | 2005 | Br. J. Cancer | pmid:15856041 |
Hata K et al. | Earlier surveillance colonoscopy programme improves survival in patients with ulcerative colitis associated colorectal cancer: results of a 23-year surveillance programme in the Japanese population. | 2003 | Br. J. Cancer | pmid:14520452 |
Harada K et al. | Genetic and epigenetic alterations of Ras signalling pathway in colorectal neoplasia: analysis based on tumour clinicopathological features. | 2007 | Br. J. Cancer | pmid:17923875 |
Span PN et al. | Carbonic anhydrase-9 expression levels and prognosis in human breast cancer: association with treatment outcome. | 2003 | Br. J. Cancer | pmid:12865916 |
Fang DD et al. | Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery. | 2010 | Br. J. Cancer | pmid:20332776 |
Tasaki M et al. | ALKBH3, a human AlkB homologue, contributes to cell survival in human non-small-cell lung cancer. | 2011 | Br. J. Cancer | pmid:21285982 |
Oladipo O et al. | The expression and prognostic impact of CXC-chemokines in stage II and III colorectal cancer epithelial and stromal tissue. | 2011 | Br. J. Cancer | pmid:21285972 |
Akagi T et al. | Induction of sodium iodide symporter gene and molecular characterisation of HNF3 beta/FoxA2, TTF-1 and C/EBP beta in thyroid carcinoma cells. | 2008 | Br. J. Cancer | pmid:18682709 |
de Graeff P et al. | Factors influencing p53 expression in ovarian cancer as a biomarker of clinical outcome in multicentre studies. | 2006 | Br. J. Cancer | pmid:16880779 |
Ieta K et al. | CEACAM6 gene expression in intrahepatic cholangiocarcinoma. | 2006 | Br. J. Cancer | pmid:16868542 |
Suzuki M et al. | Aberrant methylation of SPARC in human lung cancers. | 2005 | Br. J. Cancer | pmid:15756262 |
Cappello F et al. | CD1a expression by Barrett's metaplasia of gastric type may help to predict its evolution towards cancer. | 2005 | Br. J. Cancer | pmid:15756258 |
Hsiao JR et al. | Constitutive activation of STAT3 and STAT5 is present in the majority of nasopharyngeal carcinoma and correlates with better prognosis. | 2003 | Br. J. Cancer | pmid:12865928 |
Fukushima N et al. | Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms. | 2003 | Br. J. Cancer | pmid:12865927 |
Chang YL et al. | Roles of Fhit and p53 in Taiwanese surgically treated non-small-cell lung cancers. | 2003 | Br. J. Cancer | pmid:12865924 |
Kamura S et al. | Basic fibroblast growth factor in the bone microenvironment enhances cell motility and invasion of Ewing's sarcoma family of tumours by activating the FGFR1-PI3K-Rac1 pathway. | 2010 | Br. J. Cancer | pmid:20606682 |
Marques AR et al. | Underexpression of peroxisome proliferator-activated receptor (PPAR)gamma in PAX8/PPARgamma-negative thyroid tumours. | 2004 | Br. J. Cancer | pmid:15238980 |
Carpi A et al. | Large needle aspiration biopsy and galectin-3 determination in selected thyroid nodules with indeterminate FNA-cytology. | 2006 | Br. J. Cancer | pmid:16804521 |
Kettunen E et al. | DNA copy number loss and allelic imbalance at 2p16 in lung cancer associated with asbestos exposure. | 2009 | Br. J. Cancer | pmid:19337251 |
Kuroda M et al. | The human papillomavirus E6 and E7 inducible oncogene, hWAPL, exhibits potential as a therapeutic target. | 2005 | Br. J. Cancer | pmid:15655544 |