HEMATOXYLIN is a lipid of Polyketides (PK) class. Hematoxylin is associated with abnormalities such as Eosinophilia, Duodenal Adenoma, Senile Plaques, Morphologically altered structure and Cervical abscess. The involved functions are known as Uptake, Apoptosis, Amplification, Necrosis and Karyopyknosis. Hematoxylin often locates in Body tissue, Extracellular, Compact bone, Skin and Basement membrane. The associated genes with HEMATOXYLIN are GAPDH gene, Genome, Elastin, MERTK wt Allele and P4HTM gene.
To understand associated biological information of HEMATOXYLIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
HEMATOXYLIN is suspected in Senile Plaques, Eosinophilia, Duodenal Adenoma, Morphologically altered structure, Cervical abscess and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with HEMATOXYLIN
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Bay-Jensen AC et al. | The response to oestrogen deprivation of the cartilage collagen degradation marker, CTX-II, is unique compared with other markers of collagen turnover. | 2009 | Arthritis Res. Ther. | pmid:20527083 |
Pullerits R et al. | Induction of arthritis by high mobility group box chromosomal protein 1 is independent of tumour necrosis factor signalling. | 2008 | Arthritis Res. Ther. | pmid:18582368 |
Szyszko EA et al. | Salivary glands of primary Sjögren's syndrome patients express factors vital for plasma cell survival. | 2011 | Arthritis Res. Ther. | pmid:21214903 |
Pap T et al. | Osteoclast-independent bone resorption by fibroblast-like cells. | 2003 | Arthritis Res. Ther. | pmid:12723988 |
Hui W et al. | A model of inflammatory arthritis highlights a role for oncostatin M in pro-inflammatory cytokine-induced bone destruction via RANK/RANKL. | 2005 | Arthritis Res. Ther. | pmid:15642143 |
Roberts S et al. | Autologous chondrocyte implantation for cartilage repair: monitoring its success by magnetic resonance imaging and histology. | 2003 | Arthritis Res. Ther. | pmid:12716454 |
Sumariwalla PF et al. | The angiogenesis inhibitor protease-activated kringles 1-5 reduces the severity of murine collagen-induced arthritis. | 2003 | Arthritis Res. Ther. | pmid:12716451 |
Kelchtermans H et al. | Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-gamma. | 2005 | Arthritis Res. Ther. | pmid:15743488 |
Beyer C et al. | Hypoxia. Hypoxia in the pathogenesis of systemic sclerosis. | 2009 | Arthritis Res. Ther. | pmid:19473554 |
Frey O et al. | The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells. | 2005 | Arthritis Res. Ther. | pmid:15743476 |
Ghosh P et al. | Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cells. | 2010 | Arthritis Res. Ther. | pmid:20167057 |
Steenvoorden MM et al. | Transition of healthy to diseased synovial tissue in rheumatoid arthritis is associated with gain of mesenchymal/fibrotic characteristics. | 2006 | Arthritis Res. Ther. | pmid:17076892 |
Jin T et al. | Urokinase, a constitutive component of the inflamed synovial fluid, induces arthritis. | 2003 | Arthritis Res. Ther. | pmid:12716448 |
Magnusson SE et al. | High synovial expression of the inhibitory FcgammaRIIb in rheumatoid arthritis. | 2007 | Arthritis Res. Ther. | pmid:17521421 |
Pretzel D et al. | In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage. | 2009 | Arthritis Res. Ther. | pmid:19226472 |
Lari R et al. | The proliferative human monocyte subpopulation contains osteoclast precursors. | 2009 | Arthritis Res. Ther. | pmid:19222861 |
Le Maitre CL et al. | Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration. | 2007 | Arthritis Res. Ther. | pmid:17498290 |
Ultaigh SN et al. | Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures. | 2011 | Arthritis Res. Ther. | pmid:21345222 |
Moran EM et al. | Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-alpha, Oncostatin M and response to biologic therapies. | 2009 | Arthritis Res. Ther. | pmid:19627579 |
Iwanami K et al. | Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis. | 2008 | Arthritis Res. Ther. | pmid:18992137 |
Goedkoop AY et al. | Deactivation of endothelium and reduction in angiogenesis in psoriatic skin and synovium by low dose infliximab therapy in combination with stable methotrexate therapy: a prospective single-centre study. | 2004 | Arthritis Res. Ther. | pmid:15225368 |
Tomita T et al. | THR0921, a novel peroxisome proliferator-activated receptor gamma agonist, reduces the severity of collagen-induced arthritis. | 2006 | Arthritis Res. Ther. | pmid:16356194 |
Park YS et al. | Intra-articular injection of a nutritive mixture solution protects articular cartilage from osteoarthritic progression induced by anterior cruciate ligament transection in mature rabbits: a randomized controlled trial. | 2007 | Arthritis Res. Ther. | pmid:17257416 |
Jeffrey JE and Aspden RM | Cyclooxygenase inhibition lowers prostaglandin E2 release from articular cartilage and reduces apoptosis but not proteoglycan degradation following an impact load in vitro. | 2007 | Arthritis Res. Ther. | pmid:18096078 |
Dharmapatni AA et al. | TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis. | 2011 | Arthritis Res. Ther. | pmid:21435232 |
Reefman E et al. | Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus? | 2006 | Arthritis Res. Ther. | pmid:17014704 |
Reddy PS et al. | Mapping similarities in mTOR pathway perturbations in mouse lupus nephritis models and human lupus nephritis. | 2008 | Arthritis Res. Ther. | pmid:18980674 |
Truong LH et al. | Differential gene expression of bone anabolic factors and trabecular bone architectural changes in the proximal femoral shaft of primary hip osteoarthritis patients. | 2006 | Arthritis Res. Ther. | pmid:17187661 |
Ochaion A et al. | Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A3 adenosine receptor expression. | 2006 | Arthritis Res. Ther. | pmid:17101059 |
Gierer P et al. | Gene expression profile and synovial microcirculation at early stages of collagen-induced arthritis. | 2005 | Arthritis Res. Ther. | pmid:15987489 |
Valenti MT et al. | The effect of risedronate on osteogenic lineage is mediated by cyclooxygenase-2 gene upregulation. | 2010 | Arthritis Res. Ther. | pmid:20738860 |
Inglis JJ et al. | The differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammation. | 2005 | Arthritis Res. Ther. | pmid:15987482 |
Plantinga TS et al. | Functional consequences of DECTIN-1 early stop codon polymorphism Y238X in rheumatoid arthritis. | 2010 | Arthritis Res. Ther. | pmid:20158887 |
Le Maitre CL et al. | The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration. | 2005 | Arthritis Res. Ther. | pmid:15987475 |
Kop EN et al. | CD97 neutralisation increases resistance to collagen-induced arthritis in mice. | 2006 | Arthritis Res. Ther. | pmid:17007638 |
af Klint E et al. | Evaluation of arthroscopy and macroscopic scoring. | 2009 | Arthritis Res. Ther. | pmid:19490631 |
Teng YK et al. | Differential responsiveness to immunoablative therapy in refractory rheumatoid arthritis is associated with level and avidity of anti-cyclic citrullinated protein autoantibodies: a case study. | 2007 | Arthritis Res. Ther. | pmid:17927821 |
Mohanty ST et al. | Alterations in the self-renewal and differentiation ability of bone marrow mesenchymal stem cells in a mouse model of rheumatoid arthritis. | 2010 | Arthritis Res. Ther. | pmid:20649960 |
Heathfield SK et al. | Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration. | 2008 | Arthritis Res. Ther. | pmid:18681962 |
De Klerck B et al. | Enhanced osteoclast development in collagen-induced arthritis in interferon-gamma receptor knock-out mice as related to increased splenic CD11b+ myelopoiesis. | 2004 | Arthritis Res. Ther. | pmid:15142268 |
Dell'Accio F et al. | Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury. | 2006 | Arthritis Res. Ther. | pmid:16893455 |
Zhao X et al. | Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis. | 2008 | Arthritis Res. Ther. | pmid:18710572 |
Schmutz C et al. | Chemokine receptors in the rheumatoid synovium: upregulation of CXCR5. | 2005 | Arthritis Res. Ther. | pmid:15743468 |
Giatromanolaki A et al. | Upregulated hypoxia inducible factor-1alpha and -2alpha pathway in rheumatoid arthritis and osteoarthritis. | 2003 | Arthritis Res. Ther. | pmid:12823854 |
Sharma A et al. | Glycosaminoglycan profiles of repair tissue formed following autologous chondrocyte implantation differ from control cartilage. | 2007 | Arthritis Res. Ther. | pmid:17697352 |
Le Maitre CL et al. | Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1beta and TNFalpha expression profile. | 2007 | Arthritis Res. Ther. | pmid:17688691 |
Young CL et al. | Immunohistologic characterization of synovial membrane lymphocytes in rheumatoid arthritis. | 1984 | Arthritis Rheum. | pmid:6197977 |
Wang Y et al. | Polymerized human placenta hemoglobin (PolyPHb) attenuates myocardial infarction injury in rats. | 2012 | Artif Cells Blood Substit Immobil Biotechnol | pmid:21623696 |
He H et al. | Laser-capture microdissection and protein extraction for protein fingerprint of OSCC and OLK. | 2009 | Artif Cells Blood Substit Immobil Biotechnol | pmid:19735007 |
Kobayashi A et al. | Mucosal neuroendocrine cell abnormalities in patients with chronic constipation. | 2004 | Asian J Surg | pmid:15564160 |