HEMATOXYLIN is a lipid of Polyketides (PK) class. Hematoxylin is associated with abnormalities such as Eosinophilia, Duodenal Adenoma, Senile Plaques, Morphologically altered structure and Cervical abscess. The involved functions are known as Uptake, Apoptosis, Amplification, Necrosis and Karyopyknosis. Hematoxylin often locates in Body tissue, Extracellular, Compact bone, Skin and Basement membrane. The associated genes with HEMATOXYLIN are GAPDH gene, Genome, Elastin, MERTK wt Allele and P4HTM gene.
To understand associated biological information of HEMATOXYLIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
HEMATOXYLIN is suspected in Senile Plaques, Eosinophilia, Duodenal Adenoma, Morphologically altered structure, Cervical abscess and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with HEMATOXYLIN
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Onda T et al. | Ubiquitous mitochondrial creatine kinase downregulated in oral squamous cell carcinoma. | 2006 | Br. J. Cancer | pmid:16479256 |
Dudderidge TJ et al. | Mitogenic growth signalling, DNA replication licensing, and survival are linked in prostate cancer. | 2007 | Br. J. Cancer | pmid:17406359 |
D'Arcy V et al. | BORIS, a paralogue of the transcription factor, CTCF, is aberrantly expressed in breast tumours. | 2008 | Br. J. Cancer | pmid:18195709 |
Graf MR et al. | The neuro-steroid, 3beta androstene 17alpha diol exhibits potent cytotoxic effects on human malignant glioma and lymphoma cells through different programmed cell death pathways. | 2007 | Br. J. Cancer | pmid:17637679 |
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Barnes NL et al. | Cyclooxygenase-2 inhibition: effects on tumour growth, cell cycling and lymphangiogenesis in a xenograft model of breast cancer. | 2007 | Br. J. Cancer | pmid:17285134 |
Kaneko K et al. | Study of p53 gene alteration as a biomarker to evaluate the malignant risk of Lugol-unstained lesion with non-dysplasia in the oesophagus. | 2007 | Br. J. Cancer | pmid:17285122 |
Renaudin K et al. | Loss of NOS1 expression in high-grade renal cell carcinoma associated with a shift of NO signalling. | 2004 | Br. J. Cancer | pmid:15150612 |
Wang W et al. | Genomic analysis reveals RhoC as a potential marker in hepatocellular carcinoma with poor prognosis. | 2004 | Br. J. Cancer | pmid:15150600 |
Rennel ES et al. | VEGF(121)b, a new member of the VEGF(xxx)b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo. | 2009 | Br. J. Cancer | pmid:19707198 |
Carlsson J et al. | HER2 expression in breast cancer primary tumours and corresponding metastases. Original data and literature review. | 2004 | Br. J. Cancer | pmid:15150568 |
Kouzu Y et al. | Overexpression of stathmin in oral squamous-cell carcinoma: correlation with tumour progression and poor prognosis. | 2006 | Br. J. Cancer | pmid:16495930 |
Kummar S et al. | Cytokeratin 7 and 20 staining for the diagnosis of lung and colorectal adenocarcinoma. | 2002 | Br. J. Cancer | pmid:12085180 |
Hekmatyar SK et al. | ¹H nuclear magnetic resonance spectroscopy characterisation of metabolic phenotypes in the medulloblastoma of the SMO transgenic mice. | 2010 | Br. J. Cancer | pmid:20842126 |
Nakayama N et al. | KRAS or BRAF mutation status is a useful predictor of sensitivity to MEK inhibition in ovarian cancer. | 2008 | Br. J. Cancer | pmid:19018267 |
van Etten B et al. | Prerequisites for effective adenovirus mediated gene therapy of colorectal liver metastases in the rat using an intracellular neutralizing antibody fragment to p21-Ras. | 2002 | Br. J. Cancer | pmid:11875712 |
Zou M et al. | S100A4 (Mts1) gene overexpression is associated with invasion and metastasis of papillary thyroid carcinoma. | 2005 | Br. J. Cancer | pmid:16265347 |
Kato T et al. | Prognostic significance of microvessel density and other variables in Japanese and British patients with primary invasive breast cancer. | 2007 | Br. J. Cancer | pmid:17923874 |
Kuefer R et al. | Sodium butyrate and tributyrin induce in vivo growth inhibition and apoptosis in human prostate cancer. | 2004 | Br. J. Cancer | pmid:14735205 |
Miyoshi A et al. | Snail and SIP1 increase cancer invasion by upregulating MMP family in hepatocellular carcinoma cells. | 2004 | Br. J. Cancer | pmid:15026811 |
Dales JP et al. | Prediction of metastasis risk (11 year follow-up) using VEGF-R1, VEGF-R2, Tie-2/Tek and CD105 expression in breast cancer (n=905). | 2004 | Br. J. Cancer | pmid:15026804 |
Nakayama K et al. | Allelic loss at 19q12 and Xq11-12 predict an adverse clinical outcome in patients with mucinous ovarian tumours of low malignant potential. | 2004 | Br. J. Cancer | pmid:15026802 |
Lee KT et al. | Overexpression of Id-1 is significantly associated with tumour angiogenesis in human pancreas cancers. | 2004 | Br. J. Cancer | pmid:15026801 |
Bauer J et al. | Oncogenic GNAQ mutations are not correlated with disease-free survival in uveal melanoma. | 2009 | Br. J. Cancer | pmid:19654573 |
Cascinu S et al. | An analysis of p53, BAX and vascular endothelial growth factor expression in node-positive rectal cancer. Relationships with tumour recurrence and event-free survival of patients treated with adjuvant chemoradiation. | 2002 | Br. J. Cancer | pmid:11875737 |
Teh SK et al. | Diagnostic potential of near-infrared Raman spectroscopy in the stomach: differentiating dysplasia from normal tissue. | 2008 | Br. J. Cancer | pmid:18195711 |
Duda DG et al. | Overexpression of the p53-inducible brain-specific angiogenesis inhibitor 1 suppresses efficiently tumour angiogenesis. | 2002 | Br. J. Cancer | pmid:11875720 |
Millis RR et al. | Occult axillary lymph node metastases are of no prognostic significance in breast cancer. | 2002 | Br. J. Cancer | pmid:11875706 |
Davidson EJ et al. | Minichromosome maintenance (Mcm) proteins, cyclin B1 and D1, phosphohistone H3 and in situ DNA replication for functional analysis of vulval intraepithelial neoplasia. | 2003 | Br. J. Cancer | pmid:12610511 |
Terry G et al. | Abnormal FHIT expression profiles in cervical intraepithelial neoplastic (CIN) lesions. | 2002 | Br. J. Cancer | pmid:11875703 |
Wang JJ et al. | Study of in vitro and in vivo effects of 1,6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl]diamantane (DPD), a novel cytostatic and differentiation inducing agent, on human colon cancer cells. | 2003 | Br. J. Cancer | pmid:14612915 |
Cai H et al. | Growth-inhibitory and cell cycle-arresting properties of the rice bran constituent tricin in human-derived breast cancer cells in vitro and in nude mice in vivo. | 2004 | Br. J. Cancer | pmid:15316567 |
Hall JS et al. | Exon-array profiling unlocks clinically and biologically relevant gene signatures from formalin-fixed paraffin-embedded tumour samples. | 2011 | Br. J. Cancer | pmid:21407225 |
Bing C et al. | Adipose atrophy in cancer cachexia: morphologic and molecular analysis of adipose tissue in tumour-bearing mice. | 2006 | Br. J. Cancer | pmid:17047651 |
Graham K et al. | Gene expression in histologically normal epithelium from breast cancer patients and from cancer-free prophylactic mastectomy patients shares a similar profile. | 2010 | Br. J. Cancer | pmid:20197764 |
Hori K and Saito S | Induction of tumour blood flow stasis and necrosis: a new function for epinephrine similar to that of combretastatin A-4 derivative AVE8062 (AC7700). | 2004 | Br. J. Cancer | pmid:14735207 |
Hofer MD et al. | Expression of MTA1 promotes motility and invasiveness of PANC-1 pancreatic carcinoma cells. | 2004 | Br. J. Cancer | pmid:14735193 |
Terry G et al. | The expression of FHIT, PCNA and EGFR in benign and malignant breast lesions. | 2007 | Br. J. Cancer | pmid:17164758 |
Kahlert C et al. | Increased expression of ALCAM/CD166 in pancreatic cancer is an independent prognostic marker for poor survival and early tumour relapse. | 2009 | Br. J. Cancer | pmid:19603023 |
Dudek AZ et al. | Systemic inhibition of tumour angiogenesis by endothelial cell-based gene therapy. | 2007 | Br. J. Cancer | pmid:17653078 |
Lee YK et al. | BubR1 as a prognostic marker for recurrence-free survival rates in epithelial ovarian cancers. | 2009 | Br. J. Cancer | pmid:19603021 |
Yoshikawa D et al. | Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma. | 2008 | Br. J. Cancer | pmid:18087285 |
Negri FV et al. | Biological predictive factors in rectal cancer treated with preoperative radiotherapy or radiochemotherapy. | 2008 | Br. J. Cancer | pmid:18087284 |
Cheng HL et al. | Co-expression of RON and MET is a prognostic indicator for patients with transitional-cell carcinoma of the bladder. | 2005 | Br. J. Cancer | pmid:15870710 |
Escaff S et al. | Study of matrix metalloproteinases and their inhibitors in prostate cancer. | 2010 | Br. J. Cancer | pmid:20160732 |
Myers E et al. | A positive role for PEA3 in HER2-mediated breast tumour progression. | 2006 | Br. J. Cancer | pmid:17060941 |
Siriwardena BS et al. | Periostin is frequently overexpressed and enhances invasion and angiogenesis in oral cancer. | 2006 | Br. J. Cancer | pmid:17060937 |
Lee JW et al. | BRAF mutations in non-Hodgkin's lymphoma. | 2003 | Br. J. Cancer | pmid:14612909 |
Alain T et al. | The oncolytic effect in vivo of reovirus on tumour cells that have survived reovirus cell killing in vitro. | 2006 | Br. J. Cancer | pmid:17047650 |
Oehler MK et al. | Tissue and plasma expression of the angiogenic peptide adrenomedullin in breast cancer. | 2003 | Br. J. Cancer | pmid:14612905 |
Campbell L et al. | Caveolin-1 overexpression predicts poor disease-free survival of patients with clinically confined renal cell carcinoma. | 2003 | Br. J. Cancer | pmid:14612902 |
Kohno Y et al. | Expression of Y-box-binding protein dbpC/contrin, a potentially new cancer/testis antigen. | 2006 | Br. J. Cancer | pmid:16479255 |
Reid AH et al. | Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer. | 2010 | Br. J. Cancer | pmid:20104229 |
Shimada K et al. | Aberrant expression of RAB1A in human tongue cancer. | 2005 | Br. J. Cancer | pmid:15870709 |
Almstrup K et al. | Genome-wide gene expression profiling of testicular carcinoma in situ progression into overt tumours. | 2005 | Br. J. Cancer | pmid:15856041 |
Kallio JP et al. | Membranous location of EGFR immunostaining is associated with good prognosis in renal cell carcinoma. | 2003 | Br. J. Cancer | pmid:14520458 |
Moye VE et al. | Osteopontin expression correlates with adhesive and metastatic potential in metastasis-inducing DNA-transfected rat mammary cell lines. | 2004 | Br. J. Cancer | pmid:15150606 |
Hata K et al. | Earlier surveillance colonoscopy programme improves survival in patients with ulcerative colitis associated colorectal cancer: results of a 23-year surveillance programme in the Japanese population. | 2003 | Br. J. Cancer | pmid:14520452 |
Eves P et al. | Anti-inflammatory and anti-invasive effects of alpha-melanocyte-stimulating hormone in human melanoma cells. | 2003 | Br. J. Cancer | pmid:14612916 |
Harada K et al. | Genetic and epigenetic alterations of Ras signalling pathway in colorectal neoplasia: analysis based on tumour clinicopathological features. | 2007 | Br. J. Cancer | pmid:17923875 |
Dzięgiel P et al. | Ceramide galactosyltransferase (UGT8) is a molecular marker of breast cancer malignancy and lung metastases. | 2010 | Br. J. Cancer | pmid:20648017 |
Fang DD et al. | Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery. | 2010 | Br. J. Cancer | pmid:20332776 |
Tasaki M et al. | ALKBH3, a human AlkB homologue, contributes to cell survival in human non-small-cell lung cancer. | 2011 | Br. J. Cancer | pmid:21285982 |
Oladipo O et al. | The expression and prognostic impact of CXC-chemokines in stage II and III colorectal cancer epithelial and stromal tissue. | 2011 | Br. J. Cancer | pmid:21285972 |
Akagi T et al. | Induction of sodium iodide symporter gene and molecular characterisation of HNF3 beta/FoxA2, TTF-1 and C/EBP beta in thyroid carcinoma cells. | 2008 | Br. J. Cancer | pmid:18682709 |
Gray-Schopfer VC et al. | Cellular senescence in naevi and immortalisation in melanoma: a role for p16? | 2006 | Br. J. Cancer | pmid:16880792 |
Kita Y et al. | Expression of osteopontin in oesophageal squamous cell carcinoma. | 2006 | Br. J. Cancer | pmid:16880782 |
de Graeff P et al. | Factors influencing p53 expression in ovarian cancer as a biomarker of clinical outcome in multicentre studies. | 2006 | Br. J. Cancer | pmid:16880779 |
Suzuki M et al. | Aberrant methylation of SPARC in human lung cancers. | 2005 | Br. J. Cancer | pmid:15756262 |
Hsiao JR et al. | Constitutive activation of STAT3 and STAT5 is present in the majority of nasopharyngeal carcinoma and correlates with better prognosis. | 2003 | Br. J. Cancer | pmid:12865928 |
Fukushima N et al. | Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms. | 2003 | Br. J. Cancer | pmid:12865927 |
Chang YL et al. | Roles of Fhit and p53 in Taiwanese surgically treated non-small-cell lung cancers. | 2003 | Br. J. Cancer | pmid:12865924 |
Akil N et al. | High-risk human papillomavirus infections in breast cancer in Syrian women and their association with Id-1 expression: a tissue microarray study. | 2008 | Br. J. Cancer | pmid:18648363 |
Kamura S et al. | Basic fibroblast growth factor in the bone microenvironment enhances cell motility and invasion of Ewing's sarcoma family of tumours by activating the FGFR1-PI3K-Rac1 pathway. | 2010 | Br. J. Cancer | pmid:20606682 |
Marques AR et al. | Underexpression of peroxisome proliferator-activated receptor (PPAR)gamma in PAX8/PPARgamma-negative thyroid tumours. | 2004 | Br. J. Cancer | pmid:15238980 |
Kettunen E et al. | DNA copy number loss and allelic imbalance at 2p16 in lung cancer associated with asbestos exposure. | 2009 | Br. J. Cancer | pmid:19337251 |
Okumura H et al. | The predictive value of p53, p53R2, and p21 for the effect of chemoradiation therapy on oesophageal squamous cell carcinoma. | 2005 | Br. J. Cancer | pmid:15655547 |
Kuroda M et al. | The human papillomavirus E6 and E7 inducible oncogene, hWAPL, exhibits potential as a therapeutic target. | 2005 | Br. J. Cancer | pmid:15655544 |