| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neuroma | D009463 | 1 associated lipids |
| Encephalitis, Arbovirus | D004671 | 1 associated lipids |
| Neurofibromatoses | D017253 | 1 associated lipids |
| Heat Stroke | D018883 | 1 associated lipids |
| Post-Concussion Syndrome | D038223 | 1 associated lipids |
quercetin
quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of quercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with quercetin?
quercetin is suspected in Hypertensive disease, Cardiovascular Diseases, Atherosclerosis, Infection, Obesity, Coronary heart disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with quercetin
PubChem Associated disorders and diseases
What pathways are associated with quercetin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with quercetin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with quercetin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with quercetin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with quercetin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with quercetin?
Mouse Model
Mouse Model are used in the study 'Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver.' (Mutch DM et al., 2006), Mouse Model are used in the study 'Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma.' (Aghdassi A et al., 2007), Mouse Model are used in the study 'Proatherogenic macrophage activities are targeted by the flavonoid quercetin.' (Lara-Guzman OJ et al., 2012) and Mouse Model are used in the study 'Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease.' (Ho L et al., 2013).
Xenograft Model
Xenograft Model are used in the study 'Quercetin induces tumor-selective apoptosis through downregulation of Mcl-1 and activation of Bax.' (Cheng S et al., 2010) and Xenograft Model are used in the study 'Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations.' (Lambert JD et al., 2005).
Cancer Model
Cancer Model are used in the study 'Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin).' (Volate SR et al., 2005).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with quercetin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Liu Y et al. | Light quality affects flavonoid production and related gene expression in Cyclocarya paliurus. | 2018 | J. Photochem. Photobiol. B, Biol. | pmid:29334625 |
| Zhou JL et al. | Structures and bioactivities of seven flavonoids from Osmanthus fragrans 'Jinqiu' essential oil extraction residues. | 2018 | Nat. Prod. Res. | pmid:28431473 |
| Yamashita K et al. | Assessment of the skin sensitizing potential of chemicals, contained in foods and/or cosmetic ingredients, using a modified local lymph node assay with an elicitation phase (LLNA:DAE) method. | 2018 | J Toxicol Sci | pmid:30078837 |
| Tutino V et al. | Cannabinoid Receptor-1 Up-regulation in Azoxymethane (AOM)-treated Mice After Dietary Treatment with Quercetin. | 2018 | Anticancer Res. | pmid:30061214 |
| Jia L et al. | Quercetin suppresses the mobility of breast cancer by suppressing glycolysis through Akt-mTOR pathway mediated autophagy induction. | 2018 | Life Sci. | pmid:30025823 |
| Wu TC et al. | Quercetin and chrysin inhibit nickel-induced invasion and migration by downregulation of TLR4/NF-κB signaling in A549 cells. | 2018 | Chem. Biol. Interact. | pmid:30016632 |
| Lu N et al. | Inhibitive Effects of Quercetin on Myeloperoxidase-Dependent Hypochlorous Acid Formation and Vascular Endothelial Injury. | 2018 | J. Agric. Food Chem. | pmid:29708335 |
| Zhang Y et al. | Amelioration of Alcoholic Liver Steatosis by Dihydroquercetin through the Modulation of AMPK-Dependent Lipogenesis Mediated by P2X7R-NLRP3-Inflammasome Activation. | 2018 | J. Agric. Food Chem. | pmid:29706079 |
| Lu J et al. | Quercetin Inhibits the Migration and Invasion of HCCLM3 Cells by Suppressing the Expression of p-Akt1, Matrix Metalloproteinase (MMP) MMP-2, and MMP-9. | 2018 | Med. Sci. Monit. | pmid:29701200 |
| Aghapour F et al. | Quercetin conjugated with silica nanoparticles inhibits tumor growth in MCF-7 breast cancer cell lines. | 2018 | Biochem. Biophys. Res. Commun. | pmid:29698680 |
| Szopa A et al. | The importance of monochromatic lights in the production of phenolic acids and flavonoids in shoot cultures of Aronia melanocarpa, Aronia arbutifolia and Aronia × prunifolia. | 2018 | J. Photochem. Photobiol. B, Biol. | pmid:29351879 |
| Suvarna VM and Sangave PC | HPLC Estimation, Ex vivo Everted Sac Permeability and In Vivo Pharmacokinetic Studies of Darunavir. | 2018 | J Chromatogr Sci | pmid:29342239 |
| Abdelhalim MAK et al. | Effects of quercetin and arginine on the nephrotoxicity and lipid peroxidation induced by gold nanoparticles in vivo. | 2018 | Int J Nanomedicine | pmid:30538457 |
| de Oliveira TS et al. | Neuroprotective Effect of Camb. Leaves Is Associated with Anticholinesterase and Antioxidant Properties. | 2018 | Oxid Med Cell Longev | pmid:30420910 |
| Patrizio F et al. | The acute effect of Quercetin on muscle performance following a single resistance training session. | 2018 | Eur. J. Appl. Physiol. | pmid:29511920 |
| Song YY et al. | Phenolic Compounds from Belamcanda chinensis Seeds. | 2018 | Molecules | pmid:29510567 |
| Murota K et al. | Flavonoid metabolism: the interaction of metabolites and gut microbiota. | 2018 | Biosci. Biotechnol. Biochem. | pmid:29504827 |
| Hidaka M et al. | Food polyphenols targeting peptidyl prolyl cis/trans isomerase Pin1. | 2018 | Biochem. Biophys. Res. Commun. | pmid:29608894 |
| Wang X et al. | Hyperoside Protects Against Pressure Overload-Induced Cardiac Remodeling via the AKT Signaling Pathway. | 2018 | Cell. Physiol. Biochem. | pmid:30466089 |
| Chatzikonstantinou AV et al. | Enriching the biological space of natural products and charting drug metabolites, through real time biotransformation monitoring: The NMR tube bioreactor. | 2018 | Biochim Biophys Acta Gen Subj | pmid:28974426 |
| Liu T et al. | Production of drug nanosuspensions: effect of drug physical properties on nanosizing efficiency. | 2018 | Drug Dev Ind Pharm | pmid:28956456 |
| Mazhar M et al. | Quercetin modulates iron homeostasis and iNOS expression of splenic macrophages in a rat model of iron deficiency anemia. | 2018 | Chin J Nat Med | pmid:30197123 |
| Song JE et al. | Quercetin Inlaid Silk Fibroin/Hydroxyapatite Scaffold Promotes Enhanced Osteogenesis. | 2018 | ACS Appl Mater Interfaces | pmid:30188112 |
| Hyun HB et al. | Quercetin Suppresses CYR61-Mediated Multidrug Resistance in Human Gastric Adenocarcinoma AGS Cells. | 2018 | Molecules | pmid:29364834 |
| Akintunde JK et al. | Launaea taraxacifolia (Willd.) Amin ex C. Jeffrey inhibits oxidative damage and econucleotidase followed by increased cellular ATP in testicular cells of rats exposed to metropolitan polluted river water. | 2018 | J Basic Clin Physiol Pharmacol | pmid:29360627 |
| Wang R et al. | Quercetin Inhibits Breast Cancer Stem Cells via Downregulation of Aldehyde Dehydrogenase 1A1 (ALDH1A1), Chemokine Receptor Type 4 (CXCR4), Mucin 1 (MUC1), and Epithelial Cell Adhesion Molecule (EpCAM). | 2018 | Med. Sci. Monit. | pmid:29353288 |
| Li JJ et al. | Fast dissolving drug delivery membrane based on the ultra-thin shell of electrospun core-shell nanofibers. | 2018 | Eur J Pharm Sci | pmid:30008429 |
| Teppabut Y et al. | Change of Petals' Color and Chemical Components in Flowers during Senescence. | 2018 | Molecules | pmid:30002287 |
| Liu S et al. | Targeting heme oxygenase-1 by quercetin ameliorates alcohol-induced acute liver injury via inhibiting NLRP3 inflammasome activation. | 2018 | Food Funct | pmid:29993075 |
| Yang H et al. | Quercetin Treatment Improves Renal Function and Protects the Kidney in a Rat Model of Adenine-Induced Chronic Kidney Disease. | 2018 | Med. Sci. Monit. | pmid:29987270 |
| Yang X et al. | Quercetin synergistically reactivates human immunodeficiency virus type 1 latency by activating nuclear factor‑κB. | 2018 | Mol Med Rep | pmid:29207194 |
| Lee HN et al. | Anti‑inflammatory effect of quercetin and galangin in LPS‑stimulated RAW264.7 macrophages and DNCB‑induced atopic dermatitis animal models. | 2018 | Int. J. Mol. Med. | pmid:29207037 |
| Shen XY et al. | Quercetin inhibits okadaic acid-induced tau protein hyperphosphorylation through the Ca2+‑calpain‑p25‑CDK5 pathway in HT22 cells. | 2018 | Int. J. Mol. Med. | pmid:29207020 |
| Haque MW et al. | Taxifolin binds with LXR (α & β) to attenuate DMBA-induced mammary carcinogenesis through mTOR/Maf-1/PTEN pathway. | 2018 | Biomed. Pharmacother. | pmid:29843042 |
| Younas M et al. | Differential accumulation of silymarin induced by exposure of Silybum marianum L. callus cultures to several spectres of monochromatic lights. | 2018 | J. Photochem. Photobiol. B, Biol. | pmid:29803074 |
| Sherif IO | The effect of natural antioxidants in cyclophosphamide-induced hepatotoxicity: Role of Nrf2/HO-1 pathway. | 2018 | Int. Immunopharmacol. | pmid:29800788 |
| Zhang Y et al. | Anti-hypoglycemic and hepatocyte-protective effects of hyperoside from Zanthoxylum bungeanum leaves in mice with high-carbohydrate/high-fat diet and alloxan-induced diabetes. | 2018 | Int. J. Mol. Med. | pmid:29115390 |
| Yin C et al. | Phytochemical analysis and antibacterial activity of Gentiana macrophylla extract against bacteria isolated from burn wound infections. | 2018 | Microb. Pathog. | pmid:29111322 |
| Crascì L et al. | Anti-degenerative effect of Apigenin, Luteolin and Quercetin on human keratinocyte and chondrocyte cultures: SAR evaluation. | 2018 | Drug Res (Stuttg) | pmid:29108086 |
| Wang XF et al. | Protective Effect of Quercetin in LPS-Induced Murine Acute Lung Injury Mediated by cAMP-Epac Pathway. | 2018 | Inflammation | pmid:29569077 |
| Xiao J | Stability of dietary polyphenols: It's never too late to mend? | 2018 | Food Chem. Toxicol. | pmid:29626578 |
| Wang L et al. | Cryoprotectant choice and analyses of freeze-drying drug suspension of nanoparticles with functional stabilisers. | 2018 | J Microencapsul | pmid:29624090 |
| Quintero-Soto MF et al. | Phenolic profiles and their contribution to the antioxidant activity of selected chickpea genotypes from Mexico and ICRISAT collections. | 2018 | Plant Foods Hum Nutr | pmid:29516285 |
| Bondonno NP et al. | Flavonoid-Rich Apple Improves Endothelial Function in Individuals at Risk for Cardiovascular Disease: A Randomized Controlled Clinical Trial. | 2018 | Mol Nutr Food Res | pmid:29086478 |
| Singh S and Kumar P | Piperine in combination with quercetin halt 6-OHDA induced neurodegeneration in experimental rats: Biochemical and neurochemical evidences. | 2018 | Neurosci. Res. | pmid:29056550 |
| Palle S and Neerati P | Quercetin nanoparticles alter pharmacokinetics of bromocriptine, reflecting its enhanced inhibitory action on liver and intestinal CYP 3A enzymes in rats. | 2018 | Xenobiotica | pmid:28990837 |
| Deng M et al. | Effect of Storage Conditions on Phenolic Profiles and Antioxidant Activity of Litchi Pericarp. | 2018 | Molecules | pmid:30200581 |
| Jan S et al. | Effect of environmental variables on phytonutrients of Origanum vulgare L. in the sub-humid region of the northwestern Himalayas. | 2018 | Environ Monit Assess | pmid:30187208 |
| Cerulli A et al. | Phenolics from Castanea sativa leaves and their effects on UVB-induced damage. | 2018 | Nat. Prod. Res. | pmid:28539059 |
| Zhang XF et al. | UPLC-MS/MS analysis for antioxidant components of Lycii Fructus based on spectrum-effect relationship. | 2018 | Talanta | pmid:29332828 |