quercetin

quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model.

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Introduction

To understand associated biological information of quercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with quercetin?

quercetin is suspected in Hypertensive disease, Cardiovascular Diseases, Atherosclerosis, Infection, Obesity, Coronary heart disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with quercetin

MeSH term MeSH ID Detail
Tongue Neoplasms D014062 15 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Dermatitis D003872 30 associated lipids
Protein-Energy Malnutrition D011502 9 associated lipids
Leukemia, Lymphocytic, Chronic, B-Cell D015451 25 associated lipids
Shock D012769 11 associated lipids
Erythema D004890 22 associated lipids
Dermatomycoses D003881 17 associated lipids
Hyperalgesia D006930 42 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Fever D005334 35 associated lipids
Anaphylaxis D000707 35 associated lipids
Hyperlipidemias D006949 73 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Catalepsy D002375 30 associated lipids
Radiation Injuries, Experimental D011833 11 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Cardiomegaly D006332 31 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Leukemia, T-Cell D015458 23 associated lipids
Enterovirus Infections D004769 2 associated lipids
Hypertension, Renovascular D006978 10 associated lipids
Leishmaniasis D007896 19 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Adenoma D000236 40 associated lipids
Poultry Diseases D011201 21 associated lipids
Ascites D001201 25 associated lipids
Albuminuria D000419 18 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Vasculitis D014657 14 associated lipids
Parkinson Disease D010300 53 associated lipids
Keloid D007627 12 associated lipids
Cystitis D003556 23 associated lipids
Drug Eruptions D003875 30 associated lipids
Eye Burns D005126 13 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Retinal Detachment D012163 10 associated lipids
Synovitis D013585 15 associated lipids
Constriction, Pathologic D003251 8 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Meningeal Neoplasms D008577 5 associated lipids
Toxoplasmosis, Animal D014124 5 associated lipids
Renal Insufficiency D051437 8 associated lipids
Atherosclerosis D050197 85 associated lipids
Musculoskeletal Diseases D009140 2 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with quercetin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with quercetin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with quercetin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with quercetin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with quercetin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with quercetin?

Mouse Model

Mouse Model are used in the study 'Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver.' (Mutch DM et al., 2006), Mouse Model are used in the study 'Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma.' (Aghdassi A et al., 2007), Mouse Model are used in the study 'Proatherogenic macrophage activities are targeted by the flavonoid quercetin.' (Lara-Guzman OJ et al., 2012) and Mouse Model are used in the study 'Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease.' (Ho L et al., 2013).

Xenograft Model

Xenograft Model are used in the study 'Quercetin induces tumor-selective apoptosis through downregulation of Mcl-1 and activation of Bax.' (Cheng S et al., 2010) and Xenograft Model are used in the study 'Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations.' (Lambert JD et al., 2005).

Cancer Model

Cancer Model are used in the study 'Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin).' (Volate SR et al., 2005).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with quercetin

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Per page 10 20 50 100 | Total 12031
Authors Title Published Journal PubMed Link
Sun S et al. Metformin combined with quercetin synergistically repressed prostate cancer cells via inhibition of VEGF/PI3K/Akt signaling pathway. 2018 Gene pmid:29678660
Jeong DW et al. Deastringent Peel Extracts of Persimmon ( Thunb. cv. Cheongdo-Bansi) Protect Neuronal PC-12 and SH-SY5Y Cells against Oxidative Stress. 2018 J. Microbiol. Biotechnol. pmid:29975999
Silva W et al. Double emulsions as potential fat replacers with gallic acid and quercetin nanoemulsions in the aqueous phases. 2018 Food Chem pmid:29502846
Steinborn C et al. In Vitro Anti-inflammatory Effects of Equisetum arvense Are Not Solely Mediated by Silica. 2018 Planta Med. pmid:29202511
Mandrone M et al. Identification of a Collagenase-Inhibiting Flavonoid from Alchemilla vulgaris Using NMR-Based Metabolomics. 2018 Planta Med. pmid:29797306
Pawlikowska-Pawlega B et al. Interaction of a quercetin derivative - lensoside Aβ with liposomal membranes. 2018 Biochim Biophys Acta Biomembr pmid:29106971
Guazelli CFS et al. Quercetin attenuates zymosan-induced arthritis in mice. 2018 Biomed. Pharmacother. pmid:29554596
Wang Y et al. Quercetin reduces neural tissue damage and promotes astrocyte activation after spinal cord injury in rats. 2018 J. Cell. Biochem. pmid:28865131
Jan S et al. Effect of environmental variables on phytonutrients of Origanum vulgare L. in the sub-humid region of the northwestern Himalayas. 2018 Environ Monit Assess pmid:30187208
Zhang XF et al. UPLC-MS/MS analysis for antioxidant components of Lycii Fructus based on spectrum-effect relationship. 2018 Talanta pmid:29332828