| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neuroma | D009463 | 1 associated lipids |
| Encephalitis, Arbovirus | D004671 | 1 associated lipids |
| Neurofibromatoses | D017253 | 1 associated lipids |
| Heat Stroke | D018883 | 1 associated lipids |
| Post-Concussion Syndrome | D038223 | 1 associated lipids |
| Choroid Diseases | D015862 | 2 associated lipids |
| CREST Syndrome | D017675 | 2 associated lipids |
| Enterovirus Infections | D004769 | 2 associated lipids |
| Alcohol-Induced Disorders, Nervous System | D020268 | 2 associated lipids |
| Musculoskeletal Diseases | D009140 | 2 associated lipids |
quercetin
quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of quercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with quercetin?
quercetin is suspected in Hypertensive disease, Cardiovascular Diseases, Atherosclerosis, Infection, Obesity, Coronary heart disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with quercetin
PubChem Associated disorders and diseases
What pathways are associated with quercetin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with quercetin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with quercetin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with quercetin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with quercetin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with quercetin?
Mouse Model
Mouse Model are used in the study 'Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver.' (Mutch DM et al., 2006), Mouse Model are used in the study 'Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma.' (Aghdassi A et al., 2007), Mouse Model are used in the study 'Proatherogenic macrophage activities are targeted by the flavonoid quercetin.' (Lara-Guzman OJ et al., 2012) and Mouse Model are used in the study 'Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease.' (Ho L et al., 2013).
Xenograft Model
Xenograft Model are used in the study 'Quercetin induces tumor-selective apoptosis through downregulation of Mcl-1 and activation of Bax.' (Cheng S et al., 2010) and Xenograft Model are used in the study 'Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations.' (Lambert JD et al., 2005).
Cancer Model
Cancer Model are used in the study 'Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin).' (Volate SR et al., 2005).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with quercetin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Walkowiak A et al. | Detection of adulterants in dietary supplements with Ginkgo biloba extract by attenuated total reflectance Fourier transform infrared spectroscopy and multivariate methods PLS-DA and PCA. | 2019 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:30321862 |
| Maurya AK and Vinayak M | Improved synergistic anticancer efficacy of quercetin in combination with PI-103, rottlerin, and G0 6983 against MCF-7 and RAW 264.7 cells. | 2019 | In Vitro Cell. Dev. Biol. Anim. | pmid:30413935 |
| Li J et al. | Isoquercitrin, a flavonoid glucoside, exerts a positive effect on osteogenesis in vitro and in vivo. | 2019 | Chem. Biol. Interact. | pmid:30365939 |
| Mu Y et al. | Multifunctional quercetin conjugated chitosan nano-micelles with P-gp inhibition and permeation enhancement of anticancer drug. | 2019 | Carbohydr Polym | pmid:30318192 |
| Li F et al. | The regulation of three new members of the cytochrome P450 CYP6 family and their promoters in the cotton aphid Aphis gossypii by plant allelochemicals. | 2019 | Pest Manag. Sci. | pmid:29797492 |
| Schröder L et al. | Effects of green tea, matcha tea and their components epigallocatechin gallate and quercetin on MCF‑7 and MDA-MB-231 breast carcinoma cells. | 2019 | Oncol. Rep. | pmid:30320348 |
| Maturu P et al. | Quercetin attenuates the hyperoxic lung injury in neonatal mice: Implications for Bronchopulmonary dysplasia (BPD). | 2018 | Food Chem. Toxicol. | pmid:29432836 |
| Wang D et al. | Quercetin attenuates domoic acid-induced cognitive deficits in mice. | 2018 | Nutr Neurosci | pmid:28277184 |
| Habtemariam S and Belai A | Natural Therapies of the Inflammatory Bowel Disease: The Case of Rutin and its Aglycone, Quercetin. | 2018 | Mini Rev Med Chem | pmid:28117024 |
| Liu L et al. | One-step synthesis of fluorescent carbon dots for sensitive and selective detection of hyperin. | 2018 | Talanta | pmid:29784367 |
| Singh A et al. | Synthesis of chitin-glucan-aldehyde-quercetin conjugate and evaluation of anticancer and antioxidant activities. | 2018 | Carbohydr Polym | pmid:29773403 |
| Huang ZQ et al. | Antioxidant Activity and Hepatoprotective Potential of Quercetin 7-Rhamnoside In Vitro and In Vivo. | 2018 | Molecules | pmid:29772655 |
| Omar SH et al. | Biophenols: Enzymes (β-secretase, Cholinesterases, histone deacetylase and tyrosinase) inhibitors from olive (Olea europaea L.). | 2018 | Fitoterapia | pmid:29772299 |
| Qi F et al. | Anti-inflammatory effects of isorhamnetin on LPS-stimulated human gingival fibroblasts by activating Nrf2 signaling pathway. | 2018 | Microb. Pathog. | pmid:29704670 |
| Borovskaya TG et al. | Experimental Analysis of the Efficacy of Dihydroquercetin on the Model of Chronic Nonbacterial Inflammation of the Prostatic Gland. | 2018 | Bull. Exp. Biol. Med. | pmid:29577199 |
| Castillo RL et al. | Quercetin Prevents Diastolic Dysfunction Induced by a High-Cholesterol Diet: Role of Oxidative Stress and Bioenergetics in Hyperglycemic Rats. | 2018 | Oxid Med Cell Longev | pmid:29576853 |
| Liu J et al. | Preparation, characterization, digestibility and antioxidant activity of quercetin grafted Cynanchum auriculatum starch. | 2018 | Int. J. Biol. Macromol. | pmid:29572138 |
| Boadi WY and Lo A | Effects of Quercetin, Kaempferol, and Exogenous Glutathione on Phospho- and Total-AKT in 3T3-L1 Preadipocytes. | 2018 | J Diet Suppl | pmid:29345961 |
| Ma YK et al. | Quercetin inhibits NTHi-triggered CXCR4 activation through suppressing IKKα/NF-κB and MAPK signaling pathways in otitis media. | 2018 | Int. J. Mol. Med. | pmid:29568908 |
| Donno D et al. | New Findings in Prunus padus L. Fruits as a Source of Natural Compounds: Characterization of Metabolite Profiles and Preliminary Evaluation of Antioxidant Activity. | 2018 | Molecules | pmid:29565317 |
| Tsunekawa R et al. | Synthesis of fisetin and 2',4',6'-trihydroxydihyrochalcone 4'-O-β-neohesperidoside based on site-selective deacetylation and deoxygenation. | 2018 | Biosci. Biotechnol. Biochem. | pmid:29699439 |
| Zhou J et al. | Determination of isoquercitrin in rat plasma by high performance liquid chromatography coupled with a novel synergistic cloud point extraction. | 2018 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:29153998 |
| Chen Y et al. | Beneficial effects of hyperoside on bone metabolism in ovariectomized mice. | 2018 | Biomed. Pharmacother. | pmid:30257331 |
| Rjeibi I et al. | Extract: A New Potential Antioxidant Source against Cisplatin-Induced Liver and Kidney Injuries in Mice. | 2018 | Oxid Med Cell Longev | pmid:30254713 |
| Liu Y et al. | Geographic Variation in the Chemical Composition and Antioxidant Properties of Phenolic Compounds from (Batal) Iljinskaja Leaves. | 2018 | Molecules | pmid:30249997 |
| Naseer Z et al. | Dietary quercetin maintains the semen quality in rabbits under summer heat stress. | 2018 | Theriogenology | pmid:30243139 |
| Nakhlband A et al. | Marrubiin-loaded solid lipid nanoparticles' impact on TNF-α treated umbilical vein endothelial cells: A study for cardioprotective effect. | 2018 | Colloids Surf B Biointerfaces | pmid:29413609 |
| Omwenga EO et al. | Chitosan nanoencapsulation of flavonoids enhances their quorum sensing and biofilm formation inhibitory activities against an E.coli Top 10 biosensor. | 2018 | Colloids Surf B Biointerfaces | pmid:29413589 |
| Zhang C et al. | Mechanistic insights into the inhibition of quercetin on xanthine oxidase. | 2018 | Int. J. Biol. Macromol. | pmid:29410028 |
| Wu D et al. | Metabolite Profiles, Bioactivity, and HPLC Fingerprint of Different Varieties of Oliv.: Towards the Utilization of Medicinal and Commercial Chinese Endemic Tree. | 2018 | Molecules | pmid:30061494 |
| Fan HR et al. | Quercetin Reduces Cortical GABAergic Transmission and Alleviates MK-801-Induced Hyperactivity. | 2018 | EBioMedicine | pmid:30057312 |
| Sheth U and Bahadur A | In-vitro evaluation of cytotoxic and antioxidant properties of drugs solubilized in EO-PO star block copolymer micelles. | 2018 | Colloids Surf B Biointerfaces | pmid:30056295 |
| Chen X et al. | Plant flavonoid taxifolin inhibits the growth, migration and invasion of human osteosarcoma cells. | 2018 | Mol Med Rep | pmid:29257319 |
| Borse SP et al. | Potential synergistic effects of quercetin with other phytoconstituents of Costus pictus (insulin plant) extract in the control of hyperglycemia and prevention of NSAID-induced gastroenteropathy in diabetic rats. | 2018 | Food Chem. Toxicol. | pmid:30055312 |
| Samad N et al. | Quercetin protects against stress-induced anxiety- and depression-like behavior and improves memory in male mice. | 2018 | Physiol Res | pmid:30044120 |
| Aithal GC et al. | Localized In Situ Nanoemulgel Drug Delivery System of Quercetin for Periodontitis: Development and Computational Simulations. | 2018 | Molecules | pmid:29882751 |
| Park J et al. | Systematic metabolic profiling and bioactivity assays for bioconversion of Aceraceae family. | 2018 | PLoS ONE | pmid:29879203 |
| Nambooppha B et al. | Quercetin manipulates the expression of genes involved in the reactive oxygen species (ROS) process in chicken heterophils. | 2018 | J. Vet. Med. Sci. | pmid:29877311 |
| Lin J et al. | Steamed bread enriched with quercetin as an antiglycative food product: its quality attributes and antioxidant properties. | 2018 | Food Funct | pmid:29872802 |
| Yang Y et al. | Quercetin attenuates collagen-induced arthritis by restoration of Th17/Treg balance and activation of Heme Oxygenase 1-mediated anti-inflammatory effect. | 2018 | Int. Immunopharmacol. | pmid:29149703 |
| Lotha R et al. | Plant nutraceuticals (Quercetrin and Afzelin) capped silver nanoparticles exert potent antibiofilm effect against food borne pathogen Salmonella enterica serovar Typhi and curtail planktonic growth in zebrafish infection model. | 2018 | Microb. Pathog. | pmid:29715535 |
| Abdel Aziz RL et al. | Dose- dependent ameliorative effects of quercetin and l-Carnitine against atrazine- induced reproductive toxicity in adult male Albino rats. | 2018 | Biomed. Pharmacother. | pmid:29710542 |
| Sturza A et al. | Quercetin exerts an inhibitory effect on cellular bioenergetics of the B164A5 murine melanoma cell line. | 2018 | Mol. Cell. Biochem. | pmid:29380243 |
| Cornara L et al. | Zornia latifolia: a smart drug being adulterated by Stylosanthes guianensis. | 2018 | Int. J. Legal Med. | pmid:29362872 |
| Alves MC et al. | Taxifolin: Evaluation Through Ex vivo Permeations on Human Skin and Porcine Vaginal Mucosa. | 2018 | Curr Drug Deliv | pmid:29336264 |
| Wei X et al. | Quercetin exerts cardiovascular protective effects in LPS-induced dysfunction in vivo by regulating inflammatory cytokine expression, NF-κB phosphorylation, and caspase activity. | 2018 | Mol. Cell. Biochem. | pmid:29322353 |
| Adhikary R et al. | Clitoria ternatea flower petals: Effect on TNFR1 neutralization via downregulation of synovial matrix metalloproteases. | 2018 | J Ethnopharmacol | pmid:28826781 |
| Shaalan YM et al. | Destabilizing the interplay between miR-1275 and IGF2BPs by Tamarix articulata and quercetin in hepatocellular carcinoma. | 2018 | Nat. Prod. Res. | pmid:28817968 |
| Eren-Guzelgun B et al. | In vitro antioxidant/prooxidant effects of combined use of flavonoids. | 2018 | Nat. Prod. Res. | pmid:28669231 |
| Jiménez-López J et al. | Phytochemical profile and antioxidant activity of caper berries (Capparis spinosa L.): Evaluation of the influence of the fermentation process. | 2018 | Food Chem | pmid:29412927 |