| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neuroma | D009463 | 1 associated lipids |
| Encephalitis, Arbovirus | D004671 | 1 associated lipids |
| Neurofibromatoses | D017253 | 1 associated lipids |
| Heat Stroke | D018883 | 1 associated lipids |
| Post-Concussion Syndrome | D038223 | 1 associated lipids |
| Alcohol-Induced Disorders, Nervous System | D020268 | 2 associated lipids |
| Musculoskeletal Diseases | D009140 | 2 associated lipids |
| Prenatal Exposure Delayed Effects | D011297 | 2 associated lipids |
| CREST Syndrome | D017675 | 2 associated lipids |
| Enterovirus Infections | D004769 | 2 associated lipids |
quercetin
quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of quercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with quercetin?
quercetin is suspected in Hypertensive disease, Cardiovascular Diseases, Atherosclerosis, Infection, Obesity, Coronary heart disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with quercetin
PubChem Associated disorders and diseases
What pathways are associated with quercetin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with quercetin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with quercetin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with quercetin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with quercetin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with quercetin?
Mouse Model
Mouse Model are used in the study 'Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver.' (Mutch DM et al., 2006), Mouse Model are used in the study 'Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma.' (Aghdassi A et al., 2007), Mouse Model are used in the study 'Proatherogenic macrophage activities are targeted by the flavonoid quercetin.' (Lara-Guzman OJ et al., 2012) and Mouse Model are used in the study 'Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease.' (Ho L et al., 2013).
Xenograft Model
Xenograft Model are used in the study 'Quercetin induces tumor-selective apoptosis through downregulation of Mcl-1 and activation of Bax.' (Cheng S et al., 2010) and Xenograft Model are used in the study 'Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations.' (Lambert JD et al., 2005).
Cancer Model
Cancer Model are used in the study 'Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin).' (Volate SR et al., 2005).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with quercetin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Do SH et al. | Bone-protecting effect of Rubus coreanus by dual regulation of osteoblasts and osteoclasts. | Menopause | pmid:18709701 | |
| Tian Q et al. | Identification and determination of flavonoids in buckwheat (Fagopyrum esculentum Moench, Polygonaceae) by high-performance liquid chromatography with electrospray ionisation mass spectrometry and photodiode array ultraviolet detection. | Phytochem Anal | pmid:12918868 | |
| Rosenblat M et al. | HDL3 stimulates paraoxonase 1 antiatherogenic catalytic and biological activities in a macrophage model system: in vivo and in vitro studies. | Biofactors | pmid:25230879 | |
| pmid:11327318 | ||||
| Oksala NK et al. | Preconditioning hyperthermia inhibits restitution of isolated Guinea pig gastric mucosa. | Eur Surg Res | pmid:12364817 | |
| Priya Mohanty J et al. | Evaluation of Antioxidant Potential of Kaempferia rotunda Linn. | Indian J Pharm Sci | pmid:20046746 | |
| Filho JS et al. | Quercetin in equine frozen semen. | Cryo Letters | pmid:29734431 | |
| Dodda D et al. | Targeting oxidative stress attenuates trinitrobenzene sulphonic acid induced inflammatory bowel disease like symptoms in rats: role of quercetin. | Indian J Pharmacol | pmid:24987175 | |
| Sakai-Kashiwabara M et al. | Suppressive activity of quercetin on the production of eosinophil chemoattractants from eosinophils in vitro. | In Vivo | pmid:24982217 | |
| Chekalina N et al. | Quercetin reduces the transcriptional activity of NF-kB in stable coronary artery disease. | Indian Heart J | pmid:30392493 | |
| Xu CL et al. | Raddeanalin, a new flavonoid glycoside from the leaves of Salix raddeana Laksh. | J Asian Nat Prod Res | pmid:17701556 | |
| Onose G et al. | Integrative emphases on intimate, intrinsic propensity/pathological processes--causes of self recovery limits and also, subtle related targets for neuroprotectionl pleiotropicity/multimodal actions, by accessible therapeutic approaches--in spinal cord injuries. | J Med Life | pmid:20945817 | |
| Ferruelo A et al. | Effects of resveratrol and other wine polyphenols on the proliferation, apoptosis and androgen receptor expression in LNCaP cells. | Actas Urol Esp | pmid:24726691 | |
| Khorsandi L et al. | Quercetin induces apoptosis and necroptosis in MCF-7 breast cancer cells. | Bratisl Lek Listy | pmid:28814095 | |
| Schauss AG et al. | Toxicological and Genotoxicity Assessment of a Dihydroquercetin-Rich Dahurian Larch Tree (Larix gmelinii Rupr) Extract (Lavitol). | Int. J. Toxicol. | pmid:25850419 | |
| Robles C et al. | Phenols and flavonoids in Aleppo pine needles as bioindicators of air pollution. | J. Environ. Qual. | pmid:14674550 | |
| Kawanishi S et al. | Evaluation for safety of antioxidant chemopreventive agents. | Antioxid. Redox Signal. | pmid:16356133 | |
| Liu RN et al. | A new flavonol glycoside and activity of compounds from the flower of Nymphaea candida. | J Asian Nat Prod Res | pmid:17613618 | |
| Gülçin I et al. | Polyphenol contents and antioxidant activity of lyophilized aqueous extract of propolis from Erzurum, Turkey. | Food Chem. Toxicol. | pmid:20685228 | |
| BÅ‚aszczyk A and Skolimowski J | Synthesis and studies on antioxidants: ethoxyquin (EQ) and its derivatives. | Acta Pol Pharm | pmid:16161351 | |
| Mesbah MK et al. | HPLC determination of certain flavonoids and terpene lactones in selected Ginkgo biloba L. phytopharmaceuticals. | Farmaco | pmid:15936022 | |
| Pattanashetti LA et al. | Evaluation of neuroprotective effect of quercetin with donepezil in scopolamine-induced amnesia in rats. | Indian J Pharmacol | pmid:28458424 | |
| Choudhary MI et al. | Hemiterpene glucosides and other constituents from Spiraea canescens. | Phytochemistry | pmid:19747701 | |
| Theoharides TC and Sant GR | A pilot open label study of Cystoprotek in interstitial cystitis. | Int J Immunopathol Pharmacol | pmid:15698523 | |
| Tang YP et al. | Two new isoflavone triglycosides from the small branches of Sophora japonica. | J Asian Nat Prod Res | pmid:18058382 | |
| Azadi L et al. | Effects of Tempol and Quercetin on Human Sperm Function after Cryopreservation. | Cryo Letters | pmid:28376137 | |
| Bayés M and Rabasseda X | Gateways to clinical trials. | Methods Find Exp Clin Pharmacol | pmid:18389098 | |
| Ramezani F et al. | Sequential Therapy of Breast Cancer Cell Lines with Vitamin C and Quercetin Improves the Efficacy of Chemotherapeutic Drugs. | Nutr Cancer | pmid:28742385 | |
| pmid:23856528 | ||||
| Oliveira VM et al. | Quercetin and rutin as potential agents antifungal against Cryptococcus spp. | Braz J Biol | pmid:27166572 | |
| pmid:14646188 |