| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Uterine Cervical Neoplasms | D002583 | 10 associated lipids |
| Lead Poisoning | D007855 | 4 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
quercetin
quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of quercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with quercetin?
quercetin is suspected in Hypertensive disease, Cardiovascular Diseases, Atherosclerosis, Infection, Obesity, Coronary heart disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with quercetin
PubChem Associated disorders and diseases
What pathways are associated with quercetin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with quercetin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with quercetin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with quercetin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with quercetin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with quercetin?
Mouse Model
Mouse Model are used in the study 'Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver.' (Mutch DM et al., 2006), Mouse Model are used in the study 'Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma.' (Aghdassi A et al., 2007), Mouse Model are used in the study 'Proatherogenic macrophage activities are targeted by the flavonoid quercetin.' (Lara-Guzman OJ et al., 2012) and Mouse Model are used in the study 'Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease.' (Ho L et al., 2013).
Xenograft Model
Xenograft Model are used in the study 'Quercetin induces tumor-selective apoptosis through downregulation of Mcl-1 and activation of Bax.' (Cheng S et al., 2010) and Xenograft Model are used in the study 'Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations.' (Lambert JD et al., 2005).
Cancer Model
Cancer Model are used in the study 'Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin).' (Volate SR et al., 2005).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with quercetin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wargovich MJ and Newmark HL | Inability of several mutagen-blocking agents to inhibit 1,2-dimethylhydrazine-induced DNA-damaging activity in colonic epithelium. | 1983 | Mutat. Res. | pmid:6866005 |
| Srivastava SK et al. | Susceptibility of aldehyde and aldose reductases of human tissues to aldose reductase inhibitors. | 1982-1983 | Curr. Eye Res. | pmid:6820339 |
| Barnaulov OD et al. | [Method of assessing the effect of preparations on the ulcerogenic action of reserpine in mice]. | 1982 Jul-Aug | Farmakol Toksikol | pmid:7128778 |
| Graziani Y et al. | Regulation of protein kinases activity by quercetin in Ehrlich ascites tumor cells. | 1982 | Biochim. Biophys. Acta | pmid:6277386 |
| Cochet C et al. | Selective inhibition of a cyclic nucleotide independent protein kinase (G type casein kinase) by quercetin and related polyphenols. | 1982 | Biochem. Pharmacol. | pmid:6284174 |
| Willhite CC | Teratogenic potential of quercetin in the rat. | 1982 | Food Chem. Toxicol. | pmid:7200058 |
| Morino K et al. | Carcinogenicity test of quercetin and rutin in golden hamsters by oral administration. | 1982 | Carcinogenesis | pmid:7067042 |
| Brown SB et al. | A study of the mechanism of quercetin oxygenation by 18O labelling. A comparison of the mechanism with that of haem degradation. | 1982 | Biochem. J. | pmid:7126180 |
| Regnault-Roger C et al. | [Reduction of dehydroascorbic acid by thiols in presence of biocatalytic substances: polarographic study]. | 1982 | Int J Vitam Nutr Res | pmid:7129797 |
| Jones E and Hughes RE | Quercetin, flavonoids and the life-span of mice. | 1982 | Exp. Gerontol. | pmid:7140862 |
| Aeschbacher HU et al. | Nonmutagenicity in vivo of the food flavonol quercetin. | 1982 | Nutr Cancer | pmid:7162998 |
| Aeschbacher HU | The significance of mutagens in food. | 1982 | Prog. Clin. Biol. Res. | pmid:7167551 |
| Lee TP et al. | Effect of quercetin on human polymorphonuclear leukocyte lysosomal enzyme release and phospholipid metabolism. | 1982 | Life Sci. | pmid:6818414 |
| Sarkadi B et al. | Active calcium transport and calcium-dependent membrane phosphorylation in human peripheral blood lymphocytes. | 1982 | Cell Calcium | pmid:6288251 |
| Watson WA | The mutagenic activity of quercetin and kaempferol in Drosophila melanogaster. | 1982 | Mutat. Res. | pmid:6799807 |
| Takagi S et al. | [Studies on the constituents of Rosa sumbucina Koidz. var. pubescens Koidz]. | 1982 | Yakugaku Zasshi | pmid:6890991 |
| Siess MH and Vernevaut MF | The influence of food flavonoids on the activity of some hepatic microsomal monooxygenases in rats. | 1982 | Food Chem. Toxicol. | pmid:6891672 |
| Delamere NA and Paterson CA | Studies on calcium regulation in relation to sodium-potassium balance in the rabbit lens. | 1982 | Ophthalmic Res. | pmid:7099540 |
| Mazaki M et al. | Mutagenicity of hydrolysates of citrus fruit juices. | 1982 | Mutat. Res. | pmid:7050681 |
| White JR and Pearce FL | Effect of anti-allergic compounds on anaphylactic histamine secretion from rat peritoneal mast cells in the presence and absence of exogenous calcium. | 1982 | Immunology | pmid:6177625 |
| Middleton E and Drzewiecki G | Effects of flavonoids and transitional metal cations on antigen-induced histamine release from human basophils. | 1982 | Biochem. Pharmacol. | pmid:6178414 |
| Sacks LE and MacGregor JT | The B. subtilis multigene sporulation test for mutagens: detection of mutagens inactive in the Salmonella his reversion test. | 1982 | Mutat. Res. | pmid:6181400 |
| Eckberg WR and Carroll AG | Sequestered calcium triggers oocyte maturation in Chaetopterus. | 1982 | Cell Differ. | pmid:6811141 |
| Parker WL and Martz E | Calcium ionophore A23187 as a secretagogue for rat mast cells: does it bypass inhibition by calcium flux blockers? | 1982 | Agents Actions | pmid:6182773 |
| Beretz A et al. | Inhibition of aggregation and secretion of human platelets by quercetin and other flavonoids: structure-activity relationships. | 1982 | Agents Actions | pmid:6182778 |
| Cockcroft S | Phosphatidylinositol metabolism in mast cells and neutrophils. | 1982 | Cell Calcium | pmid:6186378 |
| Branlant G | Properties of an aldose reductase from pig lens. Comparative studies of an aldehyde reductase from pig lens. | 1982 | Eur. J. Biochem. | pmid:6819141 |
| Güttner J et al. | Effect of quercetin on the course of mengo virus infection in immunodeficient and normal mice. A histologic study. | 1982 | Acta Virol. | pmid:6127014 |
| Breitbart H and Rubinstein S | Characterization of Mg2+- and Ca2+-ATPase activity in membrane vesicles from ejaculated ram seminal plasma. | 1982 | Arch. Androl. | pmid:6128963 |
| Picq M et al. | Selective inhibition of separated forms of cyclic nucleotide phosphodiesterase from rat heart by some pentasubstituted quercetin analogs. | 1982 | Biochem. Pharmacol. | pmid:6291544 |
| Picq M et al. | Pentasubstituted quercetin analogues as selective inhibitors of particulate 3':5'-cyclic-AMP phosphodiesterase from rat brain. | 1982 | J. Med. Chem. | pmid:6292419 |
| Schwartz A et al. | Quercetin inhibition of the induction and function of cytotoxic T lymphocytes. | 1982 | Immunopharmacology | pmid:6211417 |
| Edwards SW et al. | The mitochondrial adenosine triphosphatase of Acanthamoeba castellanii. Oscillatory accumulation of enzyme activity, enzyme protein and F1-inhibitor during the cell cycle. | 1982 | Biochem. J. | pmid:6212051 |
| Kirino Y and Shimizu H | Ca2+-induced Ca2+ release from fragmented sarcoplasmic reticulum: a comparison with skinned muscle fiber studies. | 1982 | J. Biochem. | pmid:6294069 |
| Lei JQ | [Quantitative determination of quercetin in the leaves of Luo-Bu-Ma (Apocynum venetum)]. | 1982 | Zhong Yao Tong Bao | pmid:6215154 |
| Ishitsuka H et al. | Antipicornavirus flavone Ro 09-0179. | 1982 | Antimicrob. Agents Chemother. | pmid:6295260 |
| Beretz A et al. | Role of cyclic AMP in the inhibition of human platelet aggregation by quercetin, a flavonoid that potentiates the effect of prostacyclin. | 1982 | Biochem. Pharmacol. | pmid:6295405 |
| MacLennan DH et al. | Studies of Ca2+ release from sarcoplasmic reticulum. | 1982 | Ann. N. Y. Acad. Sci. | pmid:6220650 |
| EÅŸanu V et al. | The effect of an aqueous propolis extract, of rutin and of a rutin-quercetin mixture on experimental influenza virus infection in mice. | 1981 Jul-Sep | Virologie | pmid:7303493 |
| Slovacek RE and Hind G | Correlation between photosynthesis and the transthylakoid proton gradient. | 1981 | Biochim. Biophys. Acta | pmid:7236671 |
| Molnár J et al. | Antitumor activity of flavonoids on NK/Ly ascites tumor cells. | 1981 | Neoplasma | pmid:7279054 |
| Hosaka S and Hirono I | Carcinogenicity test of quercetin by pulmonary-adenoma bioassay in strain A mice. | 1981 | Gan | pmid:7286555 |
| Seddon AP and Douglas KT | Photo-induced covalent labelling of malate dehydrogenase by quercetin. | 1981 | Biochem. Biophys. Res. Commun. | pmid:7306144 |
| Hirono I et al. | Carcinogenicity examination of quercetin and rutin in ACI rats. | 1981 | Cancer Lett. | pmid:7306940 |
| Basarkar PW and Nath N | Cholesterol lowering action of vitamin P-like compounds in rats. | 1981 | Indian J. Exp. Biol. | pmid:7309166 |
| Meltz ML and MacGregor JT | Activity of the plant flavanol quercetin in the mouse lymphoma L5178Y TK+/- mutation, DNA single-strand break, and Balb/c 3T3 chemical transformation assays. | 1981 | Mutat. Res. | pmid:7254225 |
| Baba S et al. | Studies on drug metabolism by use of isotopes XXVI: Determination of urinary metabolites of rutin in humans. | 1981 | J Pharm Sci | pmid:7264927 |
| Stich HF et al. | Potentiation of genotoxicity by concurrent application of compounds found in betel quid: arecoline, eugenol, quercetin, chlorogenic acid and Mn2+. | 1981 | Mutat. Res. | pmid:7335107 |
| Klein G et al. | Photoaffinity labeling of mitochondrial adenosine triphosphatase by an azido derivative of the natural adenosine triphosphate inhibitor. | 1981 | Biochemistry | pmid:6452897 |
| Yarlett N and Lloyd D | Effects of inhibitors on mitochondrial adenosine triphosphatase of Crithidia fasciculata: an unusual pattern of specificities. | 1981 | Mol. Biochem. Parasitol. | pmid:6454844 |
| Unitt MD and Lloyd D | Effects of inhibitors on mitochondrial adenosine triphosphatase of Tetrahymena pyriformis ST. | 1981 | J. Gen. Microbiol. | pmid:6461727 |
| Long GD et al. | Effects of quercetin on magnesium-dependent adenosine triphosphatase and the metabolism of human polymorphonuclear leukocytes. | 1981 | Blood | pmid:6450623 |
| Glossmann H et al. | Quercetin inhibits tyrosine phosphorylation by the cyclic nucleotide-independent, transforming protein kinase, pp60src. | 1981 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:6269001 |
| Shoshan V and MacLennan DH | Quercetin interaction with the (Ca2+ + Mg2+)-ATPase of sarcoplasmic reticulum. | 1981 | J. Biol. Chem. | pmid:6108961 |
| Karl C et al. | [Flavonoids in the flowers of Primula officinalis]. | 1981 | Planta Med. | pmid:17401825 |
| Racker E | Energy cycles in health and disease. | 1981 | Curr. Top. Cell. Regul. | pmid:6268365 |
| Grosso A and de Sousa RC | Quercetin enhances water transport in toad bladder. | 1981 | Experientia | pmid:6268437 |
| Nagao M et al. | Mutagenicities of 61 flavonoids and 11 related compounds. | 1981 | Environ Mutagen | pmid:7021146 |
| Dazzo FB and Hrabak EM | Presence of trifoliin A, a Rhizobium-binding lectin, in clover root exudate. | 1981 | J Supramol Struct Cell Biochem | pmid:7029001 |
| Nishioka H et al. | Human saliva inactivates mutagenicity of carcinogens. | 1981 | Mutat. Res. | pmid:7029260 |
| Sahu RK et al. | Genetic toxicological of some plant flavonoids by the micronucleus test. | 1981 | Mutat. Res. | pmid:7242547 |
| Ennis M et al. | Inhibition of histamine secretion from mast cells. | 1981 | Nature | pmid:6161310 |
| Saeki K and Kurose M | Histamine release from rat mast cells sensitized with mouse antiserum. | 1981 | Agents Actions | pmid:6166178 |
| Middleton E et al. | Quercetin: an inhibitor of antigen-induced human basophil histamine release. | 1981 | J. Immunol. | pmid:6166675 |
| Truneh A and Pearce FL | Effect of anti-allergic compounds on histamine release from rat peritoneal mast cells treated with concanavalin A. | 1981 | Int. Arch. Allergy Appl. Immunol. | pmid:6167528 |
| Hrabak EM et al. | Growth-phase-dependent immunodeterminants of Rhizobium trifolii lipopolysaccharide which bind trifoliin A, a white clover lectin. | 1981 | J. Bacteriol. | pmid:6170630 |
| Kurose M | Inhibition of anaphylactic histamine release from heterologously sensitized mast cells: differential effects of drugs which interfere with calcium influx. | 1981 | Acta Med. Okayama | pmid:6172008 |
| Middleton E et al. | Effects of smooth muscle calcium antagonists on human basophil histamine release. | 1981 | Biochem. Pharmacol. | pmid:6172129 |
| Veckenstedt A and Pusztai R | Mechanism of antiviral action of quercetin against cardiovirus infection in mice. | 1981 | Antiviral Res. | pmid:6176184 |
| Wörner P | Arachidonic acid-induced chemiluminescence of human platelets: contribution of the prostaglandin and lipoxygenase pathways. | 1981 | Thromb. Haemost. | pmid:6797088 |
| Boot-Handford R and Heath H | The effects of aldose reductase inhibitors on the metabolism of cultured monkey kidney epithelial cells. | 1981 | Biochem. Pharmacol. | pmid:6802136 |
| Middleton E et al. | The flavonoids: a brief review and study of effects on antigen-induced histamine release from human basophils. | 1981 | Trans. Am. Clin. Climatol. Assoc. | pmid:6169185 |
| Cheh AM et al. | A comparison of the ability of frog and rat S-9 to activate promutagens in the Ames test. | 1980 | Environ Mutagen | pmid:7030729 |
| Fukuoka M et al. | Characterization of mutagenic principles and carcinogenicity of dill weed and seeds. | 1980 | J. Pharmacobio-dyn. | pmid:7411385 |
| El-Azizi MM et al. | Chemical constituents of Curatella americana (Dilleniaceae). | 1980 | J Pharm Sci | pmid:7381724 |
| Pamukcu AM et al. | Quercetin, a rat intestinal and bladder carcinogen present in bracken fern (Pteridium aquilinum). | 1980 | Cancer Res. | pmid:7438034 |
| Shoshan V et al. | Quercetin interaction with the chloroplast ATPase complex. | 1980 | Biochim. Biophys. Acta | pmid:6446936 |
| Shoshan V et al. | Quercetin inhibits Ca2+ uptake but not Ca2+ release by sarcoplasmic reticulum in skinned muscle fibers. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6449007 |
| Chávez E and Cuéllar A | ATP Complexes with the ATPase inhibitor quercetin. | 1980 | Life Sci. | pmid:6449644 |
| Michaelson DM et al. | ATP-stimulated Ca2+ transport into cholinergic Torpedo synaptic vesicles. | 1980 | J. Neurochem. | pmid:6108987 |
| Ramos EH et al. | Kinetics of L-[14C]leucine transport in Saccharomyces cerevisiae: effect of energy coupling inhibitors. | 1980 | Biochim. Biophys. Acta | pmid:6994811 |
| Pamukcu AM et al. | Carcinogenicity of tannin and tannin-free extracts of bracken fern (Pteridium aquilinum) in rats. | 1980 | J. Natl. Cancer Inst. | pmid:6993743 |
| Conney AH et al. | Regulation of human drug metabolism by dietary factors. | 1980 | Ciba Found. Symp. | pmid:6906262 |
| Vorbrodt A and Maul GG | Cytochemical studies on the relation of nucleoside triphosphatase activity to ribonucleoproteins in isolated rat liver nuclei. | 1980 | J. Histochem. Cytochem. | pmid:6153190 |
| Ennis M et al. | Inhibition of histamine release induced by compound 48/80 and peptide 401 in the presence and absence of calcium. Implications for the mode of action of anti-allergic compounds. | 1980 | Agents Actions | pmid:6157320 |
| Chakravarty N | The role of plasma membrane Ca++-Mg++ activated adenosine triphosphatase of rat mast cells on histamine release. | 1980 | Acta Pharmacol Toxicol (Copenh) | pmid:6160726 |
| Guy M et al. | Energization of the sugar transport mechanism in the plasmalemma of isolated mesophyll protoplasts. | 1980 | Plant Physiol. | pmid:16661233 |
| Joó F et al. | Attempts at localizing calcium in relation to synaptic transmission: an X-ray microanalytical study. | 1980 | J. Physiol. (Paris) | pmid:6256530 |
| MacLennan DH et al. | Ion pathways in proteins of the sarcoplasmic reticulum. | 1980 | Ann. N. Y. Acad. Sci. | pmid:6259987 |
| Berton G et al. | Inhibition by quercetin of activation of polymorphonuclear leucocyte functions. Stimulus-specific effects. | 1980 | Biochim. Biophys. Acta | pmid:7349882 |
| Malley A and Deppe L | Anti-timothy IgE formation: suppression with antigen D-dGl conjugates. | 1980 | Int. Arch. Allergy Appl. Immunol. | pmid:6772581 |
| Kador PF et al. | Differences in the susceptibility of various aldose reductases to inhibition. II. | 1980 | Invest. Ophthalmol. Vis. Sci. | pmid:6773903 |
| Pfister JR et al. | Synthesis and aldose reductase inhibitory activity of 7-sulfamoylxanthone-2-carboxylic acids. | 1980 | J. Med. Chem. | pmid:6779009 |
| Saito D et al. | Test of carcinogenicity of quercetin, a widely distributed mutagen in food. | 1980 | Teratog., Carcinog. Mutagen. | pmid:6119812 |
| Varma SD et al. | Refractive change in alloxan diabetic rabbits. Control by flavonoids I. | 1980 | Acta Ophthalmol (Copenh) | pmid:6782822 |
| Sarkadi B et al. | Characteristics and regulation of active calcium transport in inside-out red cell membrane vesicles. | 1980 | Biochim. Biophys. Acta | pmid:6769484 |
| Podhajcer OL et al. | Effect of liposome-encapsulated quercetin on DNA synthesis, lactate production, and cyclic adenosine 3':5'-monophosphate level in Ehrlich ascites tumor cells. | 1980 | Cancer Res. | pmid:6244093 |
| Bakker-Grunwald T et al. | K+ influx components in ascites cells: the effects of agents interacting with the (Na+ + K+)-pump. | 1980 | J. Membr. Biol. | pmid:6245215 |
| Spector M et al. | Reconstitution of the Na+K+ pump of Ehrlich ascites tumor and enhancement of efficiency by quercetin. | 1980 | J. Biol. Chem. | pmid:6247335 |
| Shute JL et al. | UDP-glucose: glucosyltransferase activity involved in the biosynthesis of flavonol triglucosides in Pisum sativum L. seedlings. | 1979 Sep-Oct | Z. Naturforsch., C, Biosci. | pmid:160697 |