| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Uterine Cervical Neoplasms | D002583 | 10 associated lipids |
| Lead Poisoning | D007855 | 4 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
quercetin
quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of quercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with quercetin?
quercetin is suspected in Hypertensive disease, Cardiovascular Diseases, Atherosclerosis, Infection, Obesity, Coronary heart disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with quercetin
PubChem Associated disorders and diseases
What pathways are associated with quercetin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with quercetin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with quercetin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with quercetin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with quercetin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with quercetin?
Mouse Model
Mouse Model are used in the study 'Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver.' (Mutch DM et al., 2006), Mouse Model are used in the study 'Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma.' (Aghdassi A et al., 2007), Mouse Model are used in the study 'Proatherogenic macrophage activities are targeted by the flavonoid quercetin.' (Lara-Guzman OJ et al., 2012) and Mouse Model are used in the study 'Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease.' (Ho L et al., 2013).
Xenograft Model
Xenograft Model are used in the study 'Quercetin induces tumor-selective apoptosis through downregulation of Mcl-1 and activation of Bax.' (Cheng S et al., 2010) and Xenograft Model are used in the study 'Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations.' (Lambert JD et al., 2005).
Cancer Model
Cancer Model are used in the study 'Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin).' (Volate SR et al., 2005).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with quercetin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Szulc-Musioł B et al. | Influence of plasma on the physical properties of ointments with quercetin. | 2017 | Acta Pharm | pmid:29337672 |
| Liang G et al. | Effect of quercetin on the transport of ritonavir to the central nervous system in vitro and in vivo. | 2016 | Acta Pharm | pmid:26959546 |
| Pepeljnjak S et al. | Antimicrobial activity of flavonoids from Pelargonium radula (Cav.) L'Hérit. | 2005 | Acta Pharm | pmid:16375833 |
| Balcerzak M et al. | Selective determination of Fe(III) in Fe(II) samples by UV-spectrophotometry with the aid of quercetin and morin. | 2008 | Acta Pharm | pmid:19103569 |
| Males Z et al. | Qualitative and quantitative analysis of flavonoids of the strawberry tree - Arbutus unedo L. (Ericaceae). | 2006 | Acta Pharm | pmid:16613729 |
| Pobłocka-Olech L et al. | TLC determination of flavonoids from different cultivars of Allium cepa and Allium ascalonicum. | 2016 | Acta Pharm | pmid:27749248 |
| Salazar M et al. | Evaluation of anti-Bothrops asper venom activity of ethanolic extract of Brownea rosademonte leaves. | 2014 | Acta Pharm | pmid:25531787 |
| Chakravarty N | The role of plasma membrane Ca++-Mg++ activated adenosine triphosphatase of rat mast cells on histamine release. | 1980 | Acta Pharmacol Toxicol (Copenh) | pmid:6160726 |
| Jin XN et al. | Hyperoside exerts anti-inflammatory and anti-arthritic effects in LPS-stimulated human fibroblast-like synoviocytes in vitro and in mice with collagen-induced arthritis. | 2016 | Acta Pharmacol. Sin. | pmid:27041460 |
| Fan PS et al. | Inhibitory effect of quercetin on proliferation of human microvascular endothelial cells in vitro. | 2003 | Acta Pharmacol. Sin. | pmid:14653949 |
| LU YL et al. | Characterization of nuciferine metabolism by P450 enzymes and uridine diphosphate glucuronosyltransferases in liver microsomes from humans and animals. | 2010 | Acta Pharmacol. Sin. | pmid:21127497 |
| Kyaw M et al. | Atheroprotective effects of antioxidants through inhibition of mitogen-activated protein kinases. | 2004 | Acta Pharmacol. Sin. | pmid:15301727 |
| Chen JW et al. | Structure-activity relationship of natural flavonoids in hydroxyl radical-scavenging effects. | 2002 | Acta Pharmacol. Sin. | pmid:12100765 |
| Liu W and Liang NC | Inhibitory effect of disodium quercetin-7,4'-disulfate on aggregation of pig platelets induced by thrombin and its mechanism. | 2000 | Acta Pharmacol. Sin. | pmid:11501184 |
| Bao XQ and Liu GT | Bicyclol protects HepG2 cells against D-galactosamine-induced apoptosis through inducing heat shock protein 27 and mitochondria associated pathway. | 2010 | Acta Pharmacol. Sin. | pmid:20139905 |
| Wang MS et al. | Inhibition of 11beta-hydroxysteroid dehydrogenase in guinea pig kidney by three bioflavonoids and their interactions with gossypol. | 2002 | Acta Pharmacol. Sin. | pmid:11860745 |
| Liu WL et al. | Protective effects of heat shock protein70 induced by geranylgeranylacetone in atrophic gastritis in rats. | 2007 | Acta Pharmacol. Sin. | pmid:17588336 |
| Gao W et al. | Quercetin ameliorates paclitaxel-induced neuropathic pain by stabilizing mast cells, and subsequently blocking PKCε-dependent activation of TRPV1. | 2016 | Acta Pharmacol. Sin. | pmid:27498772 |
| Ning N et al. | Huperzine A derivative M3 protects PC12 cells against sodium nitroprusside-induced apoptosis. | 2012 | Acta Pharmacol. Sin. | pmid:22120967 |
| Shi Y et al. | Quercetin protects rat dorsal root ganglion neurons against high glucose-induced injury in vitro through Nrf-2/HO-1 activation and NF-κB inhibition. | 2013 | Acta Pharmacol. Sin. | pmid:23770986 |