| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Uterine Cervical Neoplasms | D002583 | 10 associated lipids |
| Lead Poisoning | D007855 | 4 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
quercetin
quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of quercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with quercetin?
quercetin is suspected in Hypertensive disease, Cardiovascular Diseases, Atherosclerosis, Infection, Obesity, Coronary heart disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with quercetin
PubChem Associated disorders and diseases
What pathways are associated with quercetin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with quercetin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with quercetin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with quercetin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with quercetin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with quercetin?
Mouse Model
Mouse Model are used in the study 'Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver.' (Mutch DM et al., 2006), Mouse Model are used in the study 'Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma.' (Aghdassi A et al., 2007), Mouse Model are used in the study 'Proatherogenic macrophage activities are targeted by the flavonoid quercetin.' (Lara-Guzman OJ et al., 2012) and Mouse Model are used in the study 'Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease.' (Ho L et al., 2013).
Xenograft Model
Xenograft Model are used in the study 'Quercetin induces tumor-selective apoptosis through downregulation of Mcl-1 and activation of Bax.' (Cheng S et al., 2010) and Xenograft Model are used in the study 'Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations.' (Lambert JD et al., 2005).
Cancer Model
Cancer Model are used in the study 'Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin).' (Volate SR et al., 2005).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with quercetin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Eftekhari A et al. | Hepatoprotective and free radical scavenging actions of quercetin nanoparticles on aflatoxin B1-induced liver damage: in vitro/in vivo studies. | 2018 | Artif Cells Nanomed Biotechnol | pmid:28423950 |
| Xu MJ et al. | Inhibitory Effects of Danshen components on CYP2C8 and CYP2J2. | 2018 | Chem. Biol. Interact. | pmid:29689254 |
| Yang T et al. | Interactions of quercetin, curcumin, epigallocatechin gallate and folic acid with gelatin. | 2018 | Int. J. Biol. Macromol. | pmid:29908276 |
| Zhou W et al. | A two-step ultra-high-performance liquid chromatography-quadrupole/time of flight mass spectrometry with mass defect filtering method for rapid identification of analogues from known components of different chemical structure types in Fructus Gardeniae-Fructus Forsythiae herb pair extract and in rat's blood. | 2018 | J Chromatogr A | pmid:29861306 |
| Patra A et al. | Formulation and evaluation of mixed polymeric micelles of quercetin for treatment of breast, ovarian, and multidrug resistant cancers. | 2018 | Int J Nanomedicine | pmid:29844670 |
| Zhang X et al. | Chemical Fingerprint and Quantitative Analysis for the Quality Evaluation of Docynia dcne Leaves by High-Performance Liquid Chromatography Coupled with Chemometrics Analysis. | 2018 | J Chromatogr Sci | pmid:29800095 |
| Abdelhalim MAK et al. | The protective role of quercetin and arginine on gold nanoparticles induced hepatotoxicity in rats. | 2018 | Int J Nanomedicine | pmid:29785108 |
| Šarić Mustapić D et al. | The Inhibitory Effect of Flavonoid Aglycones on the Metabolic Activity of CYP3A4 Enzyme. | 2018 | Molecules | pmid:30301254 |
| Chen J et al. | Pretreatment with dihydroquercetin, a dietary flavonoid, protected against concanavalin A-induced immunological hepatic injury in mice and TNF-α/ActD-induced apoptosis in HepG2 cells. | 2018 | Food Funct | pmid:29589006 |
| Farrag Y et al. | Preparation of starch nanoparticles loaded with quercetin using nanoprecipitation technique. | 2018 | Int. J. Biol. Macromol. | pmid:29580996 |
| UylaÅŸ MU et al. | Quercetin dose affects the fate of hepatic ischemia and reperfusion injury in rats: An experimental research. | 2018 | Int J Surg | pmid:29578092 |
| Yu Y et al. | Nanostructured lipid carrier-based pH and temperature dual-responsive hydrogel composed of carboxymethyl chitosan and poloxamer for drug delivery. | 2018 | Int. J. Biol. Macromol. | pmid:29578017 |
| Feng J et al. | Quercetin restrains TGF-β1-induced epithelial-mesenchymal transition by inhibiting Twist1 and regulating E-cadherin expression. | 2018 | Biochem. Biophys. Res. Commun. | pmid:29425820 |
| Vovkun T et al. | Water-soluble quercetin modulates the choleresis and bile lipid ratio in rats. | 2018 | Gen. Physiol. Biophys. | pmid:29424356 |
| Zhang L et al. | Metabolomics Reveals that Dietary Ferulic Acid and Quercetin Modulate Metabolic Homeostasis in Rats. | 2018 | J. Agric. Food Chem. | pmid:29359554 |
| Li X et al. | Quercetin suppresses breast cancer stem cells (CD44/CD24) by inhibiting the PI3K/Akt/mTOR-signaling pathway. | 2018 | Life Sci. | pmid:29355544 |
| Nakamura M et al. | Differential impacts of mineralocorticoid receptor antagonist potassium canrenoate on liver and renal changes in high fat diet-mediated early hepatocarcinogenesis model rats. | 2018 | J Toxicol Sci | pmid:30298849 |
| Zeng Y et al. | Bioinformatics analysis to identify action targets in NCI-N87 gastric cancer cells exposed to quercetin. | 2018 | Pharm Biol | pmid:30266078 |
| Dymarska M et al. | Glycosylation of 3-Hydroxyflavone, 3-Methoxyflavone, Quercetin and Baicalein in Fungal Cultures of the Genus . | 2018 | Molecules | pmid:30262733 |
| Zhu X et al. | Quercetin ameliorates HFD-induced NAFLD by promoting hepatic VLDL assembly and lipophagy via the IRE1a/XBP1s pathway. | 2018 | Food Chem. Toxicol. | pmid:29438776 |
| Babotă M et al. | Phytochemical Analysis, Antioxidant and Antimicrobial Activities of Helichrysum arenarium (L.) Moench. and Antennaria dioica (L.) Gaertn. Flowers. | 2018 | Molecules | pmid:29438342 |
| Xiao L et al. | Quercetin and iron metabolism: What we know and what we need to know. | 2018 | Food Chem. Toxicol. | pmid:29432835 |
| Wu Z et al. | Simultaneous Enrichment and Separation of Four Flavonoids from Zanthoxylum bungeanum Leaves by Ultrasound-Assisted Extraction and Macroporous Resins with Evaluation of Antioxidant Activities. | 2018 | J. Food Sci. | pmid:30080245 |
| Zhou YQ et al. | Hyperoside Suppresses Lipopolysaccharide-induced Inflammation and Apoptosis in Human Umbilical Vein Endothelial Cells. | 2018 | Curr Med Sci | pmid:30074179 |
| Yao C et al. | Inhibition of enterovirus 71 replication and viral 3C protease by quercetin. | 2018 | Virol. J. | pmid:30064445 |
| Mukhopadhyay P et al. | Preparation, characterization and in vivo evaluation of pH sensitive, safe quercetin-succinylated chitosan-alginate core-shell-corona nanoparticle for diabetes treatment. | 2018 | Carbohydr Polym | pmid:29279124 |
| Rácz A et al. | Selective responses of class III plant peroxidase isoforms to environmentally relevant UV-B doses. | 2018 | J. Plant Physiol. | pmid:29272746 |
| Yan S et al. | Silk fabric dyed with extract of sophora flower bud. | 2018 | Nat. Prod. Res. | pmid:28748727 |
| Kuipers EN et al. | Quercetin Lowers Plasma Triglycerides Accompanied by White Adipose Tissue Browning in Diet-Induced Obese Mice. | 2018 | Int J Mol Sci | pmid:29914151 |
| Pathak RK et al. | Identification of new drug-like compounds from millets as Xanthine oxidoreductase inhibitors for treatment of Hyperuricemia: A molecular docking and simulation study. | 2018 | Comput Biol Chem | pmid:29906649 |
| Diamantis DA et al. | Exploring the oxidation and iron binding profile of a cyclodextrin encapsulated quercetin complex unveiled a controlled complex dissociation through a chemical stimulus. | 2018 | Biochim Biophys Acta Gen Subj | pmid:29886278 |
| Yun J et al. | Effect of isoquercitrin on membrane dynamics and apoptosis-like death in Escherichia coli. | 2018 | Biochim Biophys Acta Biomembr | pmid:29155212 |
| Wang D et al. | Quercetin protects against inflammation, MMP‑2 activation and apoptosis induction in rat model of cardiopulmonary resuscitation through modulating Bmi‑1 expression. | 2018 | Mol Med Rep | pmid:29749525 |
| Sohn EJ et al. | Restoring Effects of Natural Anti-Oxidant Quercetin on Cellular Senescent Human Dermal Fibroblasts. | 2018 | Am. J. Chin. Med. | pmid:29737207 |
| Pang XG et al. | Quercetin Stimulates Bone Marrow Mesenchymal Stem Cell Differentiation through an Estrogen Receptor-Mediated Pathway. | 2018 | Biomed Res Int | pmid:29736392 |
| Jangde R et al. | In vitro and In vivo characterization of quercetin loaded multiphase hydrogel for wound healing application. | 2018 | Int. J. Biol. Macromol. | pmid:29730004 |
| Zhuang M et al. | Islet protection and amelioration of type 2 diabetes mellitus by treatment with quercetin from the flowers of . | 2018 | Drug Des Devel Ther | pmid:29720871 |
| Yang JX et al. | Effects of phyto-oestrogen quercetin on productive performance, hormones, reproductive organs and apoptotic genes in laying hens. | 2018 | J Anim Physiol Anim Nutr (Berl) | pmid:28986927 |
| Bedada SK and Neerati P | The effect of quercetin on the pharmacokinetics of chlorzoxazone, a CYP2E1 substrate, in healthy subjects. | 2018 | Eur. J. Clin. Pharmacol. | pmid:28983678 |
| Vanden Braber NL et al. | Controlled release and antioxidant activity of chitosan or its glucosamine water-soluble derivative microcapsules loaded with quercetin. | 2018 | Int. J. Biol. Macromol. | pmid:29421395 |
| Afifi NA et al. | Hepatoprotective influence of quercetin and ellagic acid on thioacetamide-induced hepatotoxicity in rats. | 2018 | Can. J. Physiol. Pharmacol. | pmid:29414242 |
| Mao T et al. | Protective Effects of Quercetin Against Cadmium Chloride-Induced Oxidative Injury in Goat Sperm and Zygotes. | 2018 | Biol Trace Elem Res | pmid:29397540 |
| Mbikay M et al. | Mice Fed a High-Cholesterol Diet Supplemented with Quercetin-3-Glucoside Show Attenuated Hyperlipidemia and Hyperinsulinemia Associated with Differential Regulation of PCSK9 and LDLR in their Liver and Pancreas. | 2018 | Mol Nutr Food Res | pmid:29396908 |
| Suzen A et al. | Protective Effects of Hypericum perforatum and Quercetin in a Rat Model of Ischemia/Reperfusion Injury of Testes. | 2018 | Eur J Pediatr Surg | pmid:28837999 |
| Chen X et al. | Coencapsulation of (-)-Epigallocatechin-3-gallate and Quercetin in Particle-Stabilized W/O/W Emulsion Gels: Controlled Release and Bioaccessibility. | 2018 | J. Agric. Food Chem. | pmid:29578697 |
| Zhu JX et al. | Quercetin, Kaempferol and Isorhamnetin in Elaeagnus pungens Thunb. Leaf: Pharmacological Activities and Quantitative Determination Studies. | 2018 | Chem. Biodivers. | pmid:29802806 |
| Shi H et al. | Isorhamnetin, the active constituent of a Chinese herb Hippophae rhamnoides L, is a potent suppressor of dendritic-cell maturation and trafficking. | 2018 | Int. Immunopharmacol. | pmid:29272818 |
| Zhang P and Zhang X | Stimulatory effects of curcumin and quercetin on posttranslational modifications of p53 during lung carcinogenesis. | 2018 | Hum Exp Toxicol | pmid:28681665 |
| Kasmi S et al. | Modulatory effects of quercetin on liver histopathological, biochemical, hematological, oxidative stress and DNA alterations in rats exposed to graded doses of score 250. | 2018 | Toxicol. Mech. Methods | pmid:28679351 |
| Shi Q et al. | Comparative Analysis of Pigments, Phenolics, and Antioxidant Activity of Chinese Jujube ( Mill.) during Fruit Development. | 2018 | Molecules | pmid:30071615 |