apigenin
apigenin is a lipid of Polyketides (PK) class. Apigenin is associated with abnormalities such as Morphologically altered structure, Chimera disorder, Hypertensive disease, infection induced and Infection. The involved functions are known as inhibitors, Gene Expression, Process, Metabolic Inhibition and Cell Death. Apigenin often locates in Vacuole, Cytoplasmic matrix, Cytoplasm, Tissue membrane and Membrane. The associated genes with apigenin are MSMP gene, BCL2 gene, PTGS2 gene, Chromatin and SLC33A1 gene. The related lipids are Lipopolysaccharides, Steroids, 1-Butanol, agosterol A and Butyrates. The related experimental models are Mouse Model, Tissue Model, Knock-out, Xenograft Model and Disease model.
Cross Reference
Introduction
To understand associated biological information of apigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with apigenin?
apigenin is suspected in Pneumonia, Morphologically altered structure, Hypertensive disease, Dermatitis, Infection, Senile Plaques and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with apigenin
PubChem Associated disorders and diseases
What pathways are associated with apigenin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with apigenin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with apigenin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with apigenin?
Related references are published most in these journals:
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What genes are associated with apigenin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with apigenin?
Mouse Model
Mouse Model are used in the study 'Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation.' (Nicholas C et al., 2007), Mouse Model are used in the study 'Plant flavonoid apigenin inactivates Akt to trigger apoptosis in human prostate cancer: an in vitro and in vivo study.' (Kaur P et al., 2008) and Mouse Model are used in the study 'Apigenin alleviates the symptoms of Staphylococcus aureus pneumonia by inhibiting the production of alpha-hemolysin.' (Dong J et al., 2013).
Xenograft Model
Xenograft Model are used in the study 'Induction of caspase-dependent, p53-mediated apoptosis by apigenin in human neuroblastoma.' (Torkin R et al., 2005).
Tissue Model
Tissue Model are used in the study 'Dietary phytophenols curcumin, naringenin and apigenin reduce infection-induced inflammatory and contractile pathways in human placenta, foetal membranes and myometrium.' (Lim R et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with apigenin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rodriguez IF et al. | Morphological, histological, chemical and functional characterization of Prosopis alba flours of different particle sizes. | 2019 | Food Chem | pmid:30372982 |
| Li ZM et al. | Vitexin alleviates streptozotocin-induced sexual dysfunction and fertility impairments in male mice via modulating the hypothalamus-pituitary-gonadal axis. | 2019 | Chem. Biol. Interact. | pmid:30365938 |
| Zheng YZ et al. | The Substituent Effect on the Radical Scavenging Activity of Apigenin. | 2018 | Molecules | pmid:30103379 |
| Brauch D et al. | Changes in isovitexin-O-glycosylation during the development of young barley plants. | 2018 | Phytochemistry | pmid:29421507 |
| Baruah TJ et al. | Vicenin-2: a potential radiosensitizer of non-small cell lung cancer cells. | 2018 | Mol. Biol. Rep. | pmid:30099686 |
| Sun Q et al. | Apigetrin inhibits gastric cancer progression through inducing apoptosis and regulating ROS-modulated STAT3/JAK2 pathway. | 2018 | Biochem. Biophys. Res. Commun. | pmid:29408335 |
| Chen S et al. | A UPLC-ESI-MS/MS Method for Simultaneous Quantitation of Chlorogenic Acid, Scutellarin, and Scutellarein in Rat Plasma: Application to a Comparative Pharmacokinetic Study in Sham-Operated and MCAO Rats after Oral Administration of Extract. | 2018 | Molecules | pmid:30037063 |
| Ling T et al. | Novel vitexin-inspired scaffold against leukemia. | 2018 | Eur J Med Chem | pmid:29407975 |
| Yang M et al. | Apigenin prevents metabolic syndrome in high-fructose diet-fed mice by Keap1-Nrf2 pathway. | 2018 | Biomed. Pharmacother. | pmid:30021365 |
| Ashokkumar R et al. | Vitexin protects isoproterenol induced post myocardial injury by modulating hipposignaling and ER stress responses. | 2018 | Biochem. Biophys. Res. Commun. | pmid:29406244 |
| van Dooren I et al. | In vitro gastrointestinal biotransformation and characterization of a Desmodium adscendens decoction: the first step in unravelling its behaviour in the human body. | 2018 | J. Pharm. Pharmacol. | pmid:30003542 |
| Liu X et al. | Engineering yeast for the production of breviscapine by genomic analysis and synthetic biology approaches. | 2018 | Nat Commun | pmid:29386648 |
| Okitsu N et al. | Identification and Characterization of Novel Nemophila menziesii Flavone Glucosyltransferases that Catalyze Biosynthesis of Flavone 7,4'-O-Diglucoside, a Key Component of Blue Metalloanthocyanins. | 2018 | Plant Cell Physiol. | pmid:29986079 |
| Lv SX and Qiao X | Isovitexin (IV) induces apoptosis and autophagy in liver cancer cells through endoplasmic reticulum stress. | 2018 | Biochem. Biophys. Res. Commun. | pmid:29355527 |
| Mekawy AMM et al. | Apigenin pretreatment enhances growth and salinity tolerance of rice seedlings. | 2018 | Plant Physiol. Biochem. | pmid:29980098 |
| Lorizola IM et al. | Beet Stalks and Leaves ( L.) Protect Against High-Fat Diet-Induced Oxidative Damage in the Liver in Mice. | 2018 | Nutrients | pmid:29976910 |
| Vollmer M et al. | Mutual Interaction of Phenolic Compounds and Microbiota: Metabolism of Complex Phenolic Apigenin-C- and Kaempferol-O-Derivatives by Human Fecal Samples. | 2018 | J. Agric. Food Chem. | pmid:29236499 |
| Gao AM et al. | Apigenin sensitizes hepatocellular carcinoma cells to doxorubic through regulating miR-520b/ATG7 axis. | 2018 | Chem. Biol. Interact. | pmid:29191453 |
| Bai HH et al. | Hydroxycinnamoylmalated flavone C-glycosides from Lemna japonica. | 2018 | Fitoterapia | pmid:29154864 |
| Bhattacharya S et al. | Apigenin loaded nanoparticle delayed development of hepatocellular carcinoma in rats. | 2018 | Nanomedicine | pmid:29802937 |
| Gu CB et al. | Characterization, culture medium optimization and antioxidant activity of an endophytic vitexin-producing fungus Dichotomopilus funicola Y3 from pigeon pea [Cajanus cajan (L.) Millsp.]. | 2018 | J. Appl. Microbiol. | pmid:29791772 |
| Zhu J et al. | Protective effects of Hand.- Mazz. (EBHM) extract in retinal neurodegeneration models. | 2018 | Mol. Vis. | pmid:29769797 |
| Amiri M et al. | Apigenin inhibits growth of the Plasmodium berghei and disrupts some metabolic pathways in mice. | 2018 | Phytother Res | pmid:29748995 |
| Oliveira DR et al. | Flavones-bound in benzodiazepine site on GABA receptor: Concomitant anxiolytic-like and cognitive-enhancing effects produced by Isovitexin and 6-C-glycoside-Diosmetin. | 2018 | Eur. J. Pharmacol. | pmid:29738701 |
| Dang Y et al. | Protective Effect of Apigenin on Acrylonitrile-Induced Inflammation and Apoptosis in Testicular Cells via the NF-κB Pathway in Rats. | 2018 | Inflammation | pmid:29687413 |
| You P et al. | Scutellarin suppresses neuroinflammation via the inhibition of the AKT/NF-κB and p38/JNK pathway in LPS-induced BV-2 microglial cells. | 2018 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:29680917 |
| Yang J et al. | Inhibition of PI3K/Akt/mTOR pathway by apigenin induces apoptosis and autophagy in hepatocellular carcinoma cells. | 2018 | Biomed. Pharmacother. | pmid:29680738 |
| Hu JJ et al. | Isovitexin alleviates liver injury induced by lipopolysaccharide/d-galactosamine by activating Nrf2 and inhibiting NF-κB activation. | 2018 | Microb. Pathog. | pmid:29604422 |
| Vrhovac Madunić I et al. | Apigenin, a dietary flavonoid, induces apoptosis, DNA damage, and oxidative stress in human breast cancer MCF-7 and MDA MB-231 cells. | 2018 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:29541820 |
| Zhang X et al. | Scutellarin ameliorates nonalcoholic fatty liver disease through the PPARγ/PGC-1α-Nrf2 pathway. | 2018 | Free Radic. Res. | pmid:29400110 |
| Kim A and Lee CS | Apigenin reduces the Toll-like receptor-4-dependent activation of NF-κB by suppressing the Akt, mTOR, JNK, and p38-MAPK. | 2018 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:29264665 |
| Radulovic K et al. | A dietary flavone confers communicable protection against colitis through NLRP6 signaling independently of inflammasome activation. | 2018 | Mucosal Immunol | pmid:29139477 |
| Wu TC et al. | Quercetin and chrysin inhibit nickel-induced invasion and migration by downregulation of TLR4/NF-κB signaling in A549 cells. | 2018 | Chem. Biol. Interact. | pmid:30016632 |
| Nabavi SF et al. | Apigenin as neuroprotective agent: Of mice and men. | 2018 | Pharmacol. Res. | pmid:29055745 |
| Zhao Q et al. | Two CYP82D Enzymes Function as Flavone Hydroxylases in the Biosynthesis of Root-Specific 4'-Deoxyflavones in Scutellaria baicalensis. | 2018 | Mol Plant | pmid:28842248 |
| Park S et al. | Apigenin induces ROS-dependent apoptosis and ER stress in human endometriosis cells. | 2018 | J. Cell. Physiol. | pmid:28617956 |
| Abu Bakar AR et al. | Experimental and computational approaches to reveal the potential of Ficus deltoidea leaves extract as α-amylase inhibitor. | 2018 | Nat. Prod. Res. | pmid:28391727 |
| Ren K et al. | Apigenin Retards Atherogenesis by Promoting ABCA1-Mediated Cholesterol Efflux and Suppressing Inflammation. | 2018 | Cell. Physiol. Biochem. | pmid:29975943 |
| Xia Y et al. | Apigenin Suppresses the IL-1β-Induced Expression of the Urokinase-Type Plasminogen Activator Receptor by Inhibiting MAPK-Mediated AP-1 and NF-κB Signaling in Human Bladder Cancer T24 Cells. | 2018 | J. Agric. Food Chem. | pmid:29945448 |
| Wang J et al. | Scutellarin enhances osteoblast proliferation and function via NF-κB-mediated CXCR4 induction. | 2018 | Gene | pmid:29936266 |
| Wong TY et al. | Traversal of the Blood-Brain Barrier by Cleavable l-Lysine Conjugates of Apigenin. | 2018 | J. Agric. Food Chem. | pmid:29923397 |
| Šarić Mustapić D et al. | The Inhibitory Effect of Flavonoid Aglycones on the Metabolic Activity of CYP3A4 Enzyme. | 2018 | Molecules | pmid:30301254 |
| Ravisankar S et al. | Structural profile of soluble and bound phenolic compounds in teff (Eragrostis tef) reveals abundance of distinctly different flavones in white and brown varieties. | 2018 | Food Chem | pmid:29784316 |
| Alzoman NZ et al. | CE-DAD Determination of Scutellarein and Caffeic Acid in Abelia triflora Crude Extract. | 2018 | J Chromatogr Sci | pmid:29750262 |
| Jiang J et al. | Vitexin reverses the autophagy dysfunction to attenuate MCAO-induced cerebral ischemic stroke via mTOR/Ulk1 pathway. | 2018 | Biomed. Pharmacother. | pmid:29710456 |
| Lim H et al. | Flavonoids interfere with NLRP3 inflammasome activation. | 2018 | Toxicol. Appl. Pharmacol. | pmid:29960001 |
| Pei Y et al. | Combined effect of apigenin and ferulic acid on frozen-thawed boar sperm quality. | 2018 | Anim. Sci. J. | pmid:29708294 |
| Feng Y et al. | Apigenin-7-O-β-d-(-6″-p-coumaroyl)-glucopyranoside pretreatment attenuates myocardial ischemia/reperfusion injury via activating AMPK signaling. | 2018 | Life Sci. | pmid:29705352 |
| Malar DS et al. | Grewia tiliaefolia and its active compound vitexin regulate the expression of glutamate transporters and protect Neuro-2a cells from glutamate toxicity. | 2018 | Life Sci. | pmid:29704481 |
| Hadrich F and Sayadi S | Apigetrin inhibits adipogenesis in 3T3-L1 cells by downregulating PPARγ and CEBP-α. | 2018 | Lipids Health Dis | pmid:29695233 |
| Lu Y et al. | Vitexin attenuates lipopolysaccharide-induced acute lung injury by controlling the Nrf2 pathway. | 2018 | PLoS ONE | pmid:29694408 |
| Gurunathan S et al. | Antibacterial Efficacy of Silver Nanoparticles on Endometritis Caused by and in Dairy Cattle. | 2018 | Int J Mol Sci | pmid:29659523 |
| Karamać M et al. | Phenolic contents and antioxidant capacities of wild and cultivated white lupin (Lupinus albus L.) seeds. | 2018 | Food Chem | pmid:29655709 |
| Mo J et al. | Scutellarin protects against vascular endothelial dysfunction and prevents atherosclerosis via antioxidation. | 2018 | Phytomedicine | pmid:29655699 |
| Kumar KS et al. | Isolation, identification and characterization of apigenin from Justicia gendarussa and its anti-inflammatory activity. | 2018 | Int. Immunopharmacol. | pmid:29655057 |
| Hu M et al. | Vitexin protects dopaminergic neurons in MPTP-induced Parkinson's disease through PI3K/Akt signaling pathway. | 2018 | Drug Des Devel Ther | pmid:29588573 |
| Elhennawy MG and Lin HS | Dose- and time-dependent pharmacokinetics of apigenin trimethyl ether. | 2018 | Eur J Pharm Sci | pmid:29574080 |
| Malar DS et al. | Vitexin inhibits Aβ induced toxicity in Neuro-2a cells by augmenting Nrf-2/HO-1 dependent antioxidant pathway and regulating lipid homeostasis by the activation of LXR-α. | 2018 | Toxicol In Vitro | pmid:29545167 |
| Yang YC and Wei MC | Development and characterization of a green procedure for apigenin extraction from Scutellaria barbata D. Don. | 2018 | Food Chem | pmid:29478557 |
| Witkowska-Banaszczak E | Flavonoids from Trollius europaeus flowers and evaluation of their biological activity. | 2018 | J. Pharm. Pharmacol. | pmid:29466602 |
| Chledzik S et al. | Pharmacological Effects of Scutellarin, An Active Component of Genus Scutellaria and Erigeron: A Systematic Review. | 2018 | Am. J. Chin. Med. | pmid:29433387 |
| Zhu Q et al. | Comparison of flavonoids and isoflavonoids to inhibit rat and human 11β-hydroxysteroid dehydrogenase 1 and 2. | 2018 | Steroids | pmid:29425740 |
| Tao Y et al. | Pharmacokinetic comparisons of six components from raw and vinegar-processed Daphne genkwa aqueous extracts following oral administration in rats by employing UHPLC-MS/MS approaches. | 2018 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:29428673 |
| Srivastava A et al. | Swertisin ameliorates diabetes by triggering pancreatic progenitors for islet neogenesis in Streptozotocin treated BALB/c mice. | 2018 | Biomed. Pharmacother. | pmid:29428671 |
| Melguizo-RodrÃguez L et al. | Effect of olive oil phenolic compounds on osteoblast differentiation. | 2018 | Eur. J. Clin. Invest. | pmid:29392706 |
| Jin UH et al. | Structure-Dependent Modulation of Aryl Hydrocarbon Receptor-Mediated Activities by Flavonoids. | 2018 | Toxicol. Sci. | pmid:29584932 |
| Ni G et al. | Synthesis of Scutellarein Derivatives with a Long Aliphatic Chain and Their Biological Evaluation against Human Cancer Cells. | 2018 | Molecules | pmid:29389889 |
| Rimal H et al. | Hydroxylation of Resveratrol with DoxA In Vitro: An Enzyme with the Potential for the Bioconversion of a Bioactive Stilbene. | 2018 | J. Microbiol. Biotechnol. | pmid:29385664 |
| Zhang G et al. | Vitexin induces G2/M‑phase arrest and apoptosis via Akt/mTOR signaling pathway in human glioblastoma cells. | 2018 | Mol Med Rep | pmid:29328424 |
| Baluchnejadmojarad T et al. | Scutellarin alleviates lipopolysaccharide-induced cognitive deficits in the rat: Insights into underlying mechanisms. | 2018 | Int. Immunopharmacol. | pmid:29190543 |
| Madunić J et al. | Apigenin: A dietary flavonoid with diverse anticancer properties. | 2018 | Cancer Lett. | pmid:29097249 |
| Akogou FU et al. | Extraction methods and food uses of a natural red colorant from dye sorghum. | 2018 | J. Sci. Food Agric. | pmid:28600852 |
| Zhong Y et al. | Scaffold Hopping Strategy for the Design, Synthesis and Biological Activity Evaluation of Novel Hexacyclic Scutellarein Derivatives with a 1,3-Oxazine Ring Fused at A-ring. | 2018 | Med Chem | pmid:28875860 |
| Renda G et al. | Evaluation of in vivo analgesic activity of Scrophularia kotscyhana and isolation of bioactive compounds through activity-guided fractionation. | 2018 | Nat. Prod. Res. | pmid:28758426 |
| Gaspar MC et al. | Polyphenolic characterisation and bioactivity of an Oxalis pes-caprae L. leaf extract. | 2018 | Nat. Prod. Res. | pmid:28627294 |
| Abdel-Salam NA et al. | Flavonoids of Alcea rosea L. and their immune stimulant, antioxidant and cytotoxic activities on hepatocellular carcinoma HepG-2 cell line. | 2018 | Nat. Prod. Res. | pmid:28580799 |
| Kiyekbayeva L et al. | Phytochemical constituents and antioxidant activity of Echinops albicaulis. | 2018 | Nat. Prod. Res. | pmid:28475371 |
| Zengin G et al. | Multiple pharmacological approaches on Fibigia eriocarpa extracts by in vitro and computational assays. | 2018 | Fundam Clin Pharmacol | pmid:29505673 |
| Bougioukas I et al. | Apigenin Reduces NF-κB and Subsequent Cytokine Production as Protective Effect in a Rodent Animal Model of Lung Ischemia-Reperfusion Injury. | 2018 | J Invest Surg | pmid:28340319 |
| Crascì L et al. | Anti-degenerative effect of Apigenin, Luteolin and Quercetin on human keratinocyte and chondrocyte cultures: SAR evaluation. | 2018 | Drug Res (Stuttg) | pmid:29108086 |
| Xin Z et al. | UPLC-Orbitrap-MS/MS combined with chemometrics establishes variations in chemical components in green tea from Yunnan and Hunan origins. | 2018 | Food Chem | pmid:30381222 |
| Mendel M et al. | Interactions between erythromycin, flunixin meglumine, levamisole and plant secondary metabolites towards bovine gastrointestinal motility-in vitro study. | 2018 | J. Vet. Pharmacol. Ther. | pmid:28913883 |
| Li Y et al. | Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects. | 2018 | Toxicol. Lett. | pmid:29753067 |
| Cornara L et al. | Zornia latifolia: a smart drug being adulterated by Stylosanthes guianensis. | 2018 | Int. J. Legal Med. | pmid:29362872 |
| Cheruvu HS et al. | LC-MS/MS method for the simultaneous quantification of luteolin, wedelolactone and apigenin in mice plasma using hansen solubility parameters for liquid-liquid extraction: Application to pharmacokinetics of Eclipta alba chloroform fraction. | 2018 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:29518720 |
| Chassagne F et al. | A metabolomic approach to identify anti-hepatocarcinogenic compounds from plants used traditionally in the treatment of liver diseases. | 2018 | Fitoterapia | pmid:29477305 |
| van Vugt-Lussenburg BMA et al. | Incorporation of metabolic enzymes to improve predictivity of reporter gene assay results for estrogenic and anti-androgenic activity. | 2018 | Reprod. Toxicol. | pmid:29162470 |
| Xu L et al. | Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects. | 2018 | J. Exp. Clin. Cancer Res. | pmid:30373602 |
| Vieira FN et al. | Long-Term Effect on Bioactive Components and Antioxidant Activity of Thermal and High-Pressure Pasteurization of Orange Juice. | 2018 | Molecules | pmid:30347848 |
| Wang X et al. | Effect of apigenin on apoptosis induced by renal ischemia/reperfusion injury in vivo and in vitro. | 2018 | Ren Fail | pmid:30278824 |
| Han T et al. | Synthesis of scutellarein derivatives with antiproliferative activity and selectivity through the intrinsic pathway. | 2018 | Eur J Med Chem | pmid:30243153 |
| Ojo OA et al. | Chromatographic fingerprint analysis, antioxidant properties, and inhibition of cholinergic enzymes (acetylcholinesterase and butyrylcholinesterase) of phenolic extracts from Irvingia gabonensis (Aubry-Lecomte ex O'Rorke) Baill bark. | 2018 | J Basic Clin Physiol Pharmacol | pmid:29381472 |
| Thangaiyan R et al. | Preventive effect of apigenin against isoproterenol-induced apoptosis in cardiomyoblasts. | 2018 | J. Biochem. Mol. Toxicol. | pmid:30152906 |
| Shin JW et al. | Scutellarin Ameliorates Learning and Memory Deficit via Suppressing [Formula: see text]-Amyloid Formation and Microglial Activation in Rats with Chronic Cerebral Hypoperfusion. | 2018 | Am. J. Chin. Med. | pmid:30149759 |
| Kim HJ et al. | Spirodela polyrhiza and its Chemical Constituent Vitexin Exert Anti-Allergic Effect via ORAI1 Channel Inhibition. | 2018 | Am. J. Chin. Med. | pmid:30149756 |
| Feng X et al. | Characterization of the In Vivo and In Vitro Metabolites of Linarin in Rat Biosamples and Intestinal Flora Using Ultra-High Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Tandem Mass Spectrometry. | 2018 | Molecules | pmid:30149616 |
| Kang CH et al. | Apigenin promotes TRAIL-mediated apoptosis regardless of ROS generation. | 2018 | Food Chem. Toxicol. | pmid:29247770 |
| Makanjuola SBL et al. | Apigenin and apigeninidin isolates from the Sorghum bicolor leaf targets inflammation via cyclo-oxygenase-2 and prostaglandin-E blockade. | 2018 | Int J Rheum Dis | pmid:30146750 |
| Chang JH et al. | Downregulating CD26/DPPIV by apigenin modulates the interplay between Akt and Snail/Slug signaling to restrain metastasis of lung cancer with multiple EGFR statuses. | 2018 | J. Exp. Clin. Cancer Res. | pmid:30134935 |
| Mirzoeva S et al. | Apigenin Inhibits UVB-Induced Skin Carcinogenesis: The Role of Thrombospondin-1 as an Anti-Inflammatory Factor. | 2018 | Neoplasia | pmid:30118999 |