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Simultaneous Ultra Performance Liquid Chromatography Determination and Antioxidant Activity of Linarin, Luteolin, Chlorogenic Acid and Apigenin in Different Parts of Compositae Species. |
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Molecules |
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Alpha B-Crystallin Protects Rat Articular Chondrocytes against Casein Kinase II Inhibition-Induced Apoptosis. |
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PLoS ONE |
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Analogs of Natural 3-Deoxyanthocyanins: O-Glucosides of the 4',7-Dihydroxyflavylium Ion and the Deep Influence of Glycosidation on Color. |
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Int J Mol Sci |
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Pharmacokinetic Comparison of Scutellarin and Paeoniflorin in Sham-Operated and Middle Cerebral Artery Occlusion Ischemia and Reperfusion Injury Rats after Intravenous Administration of Xin-Shao Formula. |
2016 |
Molecules |
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Single-Laboratory Validation for the Determination of Flavonoids in Hawthorn Leaves and Finished Products by LC-UV. |
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Resveratrol, piperine and apigenin differ in their NADPH-oxidase inhibitory and reactive oxygen species-scavenging properties. |
2016 |
Phytomedicine |
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Scutellarin attenuates vasospasm through the Erk5-KLF2-eNOS pathway after subarachnoid hemorrhage in rats. |
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J Clin Neurosci |
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Characterisation of phenolic antioxidants in Scabiosa arenaria flowers by LC-ESI-MS/MS and NMR. |
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LC-MS analysis of phenolic compounds and antioxidant activity of buckwheat at different stages of malting. |
2016 |
Food Chem |
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Development and validation of HPLC method for vicenin-1 isolated from fenugreek seeds in rat plasma: application to pharmacokinetic, tissue distribution and excretion studies. |
2016 |
Pharm Biol |
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Protective Effects of Apigenin Against Paraquat-Induced Acute Lung Injury in Mice. |
2016 |
Inflammation |
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Scutellarin protects cardiomyocyte ischemia-reperfusion injury by reducing apoptosis and oxidative stress. |
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Life Sci. |
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Vicenin-2 and scolymoside inhibit high-glucose-induced vascular inflammation in vitro and in vivo. |
2016 |
Can. J. Physiol. Pharmacol. |
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Comparative evaluation of the effect of cyclodextrins and pH on aqueous solubility of apigenin. |
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J Pharm Biomed Anal |
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Apigenin, a natural flavonoid, inhibits glutamate release in the rat hippocampus. |
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Eur. J. Pharmacol. |
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Apigenin promotes osteogenic differentiation of human mesenchymal stem cells through JNK and p38 MAPK pathways. |
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Mol. Cell. Biochem. |
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The flavone apigenin blocks nuclear translocation of sterol regulatory element-binding protein-2 in the hepatic cells WRL-68. |
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Probing the potential of apigenin liposomes in enhancing bacterial membrane perturbation and integrity loss. |
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J Colloid Interface Sci |
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Effects of Citrus Flavonoids Against Microvascular Damage Induced by Hypoperfusion and Reperfusion in Rat Pial Circulation. |
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Microcirculation |
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Design, synthesis, and biological evaluation of scutellarein carbamate derivatives as potential multifunctional agents for the treatment of Alzheimer's disease. |
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Chem Biol Drug Des |
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Apigenin induces caspase-dependent apoptosis by inhibiting signal transducer and activator of transcription 3 signaling in HER2-overexpressing SKBR3 breast cancer cells. |
2015 |
Mol Med Rep |
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Scutellarin attenuates endothelium-dependent aasodilation impairment induced by hypoxia reoxygenation, through regulating the PKG signaling pathway in rat coronary artery. |
2015 |
Chin J Nat Med |
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Induction of NRF2-mediated gene expression by dietary phytochemical flavones apigenin and luteolin. |
2015 |
Biopharm Drug Dispos |
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Pharmacokinetics and tissue distribution study of Isovitexin in rats by HPLC-MS/MS. |
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J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
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Inhibition of autophagy ameliorates atherogenic inflammation by augmenting apigenin-induced macrophage apoptosis. |
2015 |
Int. Immunopharmacol. |
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[Effect of apigenin on protein expressions of PPARs in liver tissues of rats with nonalcoholic steatohepatitis]. |
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Zhonghua Gan Zang Bing Za Zhi |
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Involvement of CAR and PXR in the transcriptional regulation of CYP2B6 gene expression by ingredients from herbal medicines. |
2015 |
Xenobiotica |
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Ultra high performance liquid chromatography with electrospray ionization tandem mass spectrometry coupled with hierarchical cluster analysis to evaluate Wikstroemia indica (L.) C. A. Mey. from different geographical regions. |
2015 |
J Sep Sci |
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Effects of germination on the nutritional properties, phenolic profiles, and antioxidant activities of buckwheat. |
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Vitexin protects brain against ischemia/reperfusion injury via modulating mitogen-activated protein kinase and apoptosis signaling in mice. |
2015 |
Phytomedicine |
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Design, synthesis and evaluation of scutellarein-O-alkylamines as multifunctional agents for the treatment of Alzheimer's disease. |
2015 |
Eur J Med Chem |
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Effect of Apigenin on Leishmania amazonensis Is Associated with Reactive Oxygen Species Production Followed by Mitochondrial Dysfunction. |
2015 |
J. Nat. Prod. |
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Eriocitrin and Apigenin as New Carbonic Anhydrase VA Inhibitors from a Virtual Screening of Calabrian Natural Products. |
2015 |
Planta Med. |
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Effect of soaking and fermentation on content of phenolic compounds of soybean (Glycine max cv. Merit) and mung beans (Vigna radiata [L] Wilczek). |
2015 |
Int J Food Sci Nutr |
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Investigation on the interactions of scutellarin and scutellarein with bovine serum albumin using spectroscopic and molecular docking techniques. |
2015 |
Arch. Pharm. Res. |
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Synthetic analogues of flavonoids with improved activity against platelet activation and aggregation as novel prototypes of food supplements. |
2015 |
Food Chem |
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Development and validation of an HPTLC method for apigenin 7-O-glucoside in chamomile flowers and its application for fingerprint discrimination of chamomile-like materials. |
2015 |
J Pharm Biomed Anal |
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Protective effects of apigenin against 1-methyl-4-phenylpyridinium ion‑induced neurotoxicity in PC12 cells. |
2015 |
Int. J. Mol. Med. |
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Biological evaluation and molecular docking of baicalin and scutellarin as Helicobacter pylori urease inhibitors. |
2015 |
J Ethnopharmacol |
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Yang L et al. |
Enhanced action of apigenin and naringenin combination on estrogen receptor activation in non-malignant colonocytes: implications on sorghum-derived phytoestrogens. |
2015 |
Food Funct |
pmid:25553799
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Zhang S et al. |
Studies on the interaction of apigenin with calf thymus DNA by spectroscopic methods. |
2015 |
Spectrochim Acta A Mol Biomol Spectrosc |
pmid:25459730
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Inhibition of IL-6/STAT3 axis and targeting Axl and Tyro3 receptor tyrosine kinases by apigenin circumvent taxol resistance in ovarian cancer cells. |
2015 |
Int. J. Oncol. |
pmid:25544427
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Antioxidant activities and quali-quantitative analysis of different Smallanthus sonchifolius [(Poepp. and Endl.) H. Robinson] landrace extracts. |
2015 |
Nat. Prod. Res. |
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Unusual C,O-Fused Glycosylapigenins from Serjania marginata Leaves. |
2015 |
J. Nat. Prod. |
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Anti-angiogenic activity of Entada africana root. |
2015 |
Nat. Prod. Res. |
pmid:25482106
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Activity of the dietary flavonoid, apigenin, against multidrug-resistant tumor cells as determined by pharmacogenomics and molecular docking. |
2015 |
J. Nutr. Biochem. |
pmid:25459885
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Flavonoid nanocrystals produced by ARTcrystal®-technology. |
2015 |
Int J Pharm |
pmid:25448550
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Effects of vitexin on the pharmacokinetics and mRNA expression of CYP isozymes in rats. |
2015 |
Phytother Res |
pmid:25447838
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Apigenin manipulates the ubiquitin-proteasome system to rescue estrogen receptor-β from degradation and induce apoptosis in prostate cancer cells. |
2015 |
Eur J Nutr |
pmid:25408199
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Luteolin and Apigenin Attenuate 4-Hydroxy-2-Nonenal-Mediated Cell Death through Modulation of UPR, Nrf2-ARE and MAPK Pathways in PC12 Cells. |
2015 |
PLoS ONE |
pmid:26087007
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Apigenin as an anti-quinolone-resistance antibiotic. |
2015 |
Int. J. Antimicrob. Agents |
pmid:26526895
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Induction of caspase-dependent extrinsic apoptosis by apigenin through inhibition of signal transducer and activator of transcription 3 (STAT3) signalling in HER2-overexpressing BT-474 breast cancer cells. |
2015 |
Biosci. Rep. |
pmid:26500281
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Combination Therapy of LysGH15 and Apigenin as a New Strategy for Treating Pneumonia Caused by Staphylococcus aureus. |
2015 |
Appl. Environ. Microbiol. |
pmid:26475103
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Nakajima A et al. |
A new flavanone and other flavonoids from green perilla leaf extract inhibit nitric oxide production in interleukin 1β-treated hepatocytes. |
2015 |
Biosci. Biotechnol. Biochem. |
pmid:25266050
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Scutellarin's Cardiovascular Endothelium Protective Mechanism: Important Role of PKG-Iα. |
2015 |
PLoS ONE |
pmid:26440524
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Willenberg I et al. |
Food Polyphenols Fail to Cause a Biologically Relevant Reduction of COX-2 Activity. |
2015 |
PLoS ONE |
pmid:26440517
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Chen X et al. |
Effect of scutellarin on the metabolism and pharmacokinetics of clopidogrel in rats. |
2015 |
Biopharm Drug Dispos |
pmid:25256597
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Apigenin blocks IKKα activation and suppresses prostate cancer progression. |
2015 |
Oncotarget |
pmid:26435478
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Deglycosylation of isoflavone C-glycosides by newly isolated human intestinal bacteria. |
2015 |
J. Sci. Food Agric. |
pmid:25199800
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Modulation of thyroidal radioiodide uptake by oncological pipeline inhibitors and Apigenin. |
2015 |
Oncotarget |
pmid:26397139
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Suppression of NF-κB and NF-κB-Regulated Gene Expression by Apigenin through IκBα and IKK Pathway in TRAMP Mice. |
2015 |
PLoS ONE |
pmid:26379052
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Sun J et al. |
Chemical Constituents and Antibacterial Properties of Indocalamus latifolius McClure Leaves, the Packaging Material for "Zongzi". |
2015 |
Molecules |
pmid:26343625
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Fang J et al. |
Apigenin inhibits the proliferation of adenoid cystic carcinoma via suppression of glucose transporter-1. |
2015 |
Mol Med Rep |
pmid:26300442
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Falcone Ferreyra ML et al. |
The Identification of Maize and Arabidopsis Type I FLAVONE SYNTHASEs Links Flavones with Hormones and Biotic Interactions. |
2015 |
Plant Physiol. |
pmid:26269546
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Cattaneo L et al. |
Anti-Proliferative Effect of Rosmarinus officinalis L. Extract on Human Melanoma A375 Cells. |
2015 |
PLoS ONE |
pmid:26176704
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Apigenin inhibits indoxyl sulfate-induced endoplasmic reticulum stress and anti-proliferative pathways, CHOP and IL-6/p21, in human renal proximal tubular cells. |
2015 |
Eur Rev Med Pharmacol Sci |
pmid:26166660
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Zhang Y et al. |
Apigenin induces dermal collagen synthesis via smad2/3 signaling pathway. |
2015 |
Eur J Histochem |
pmid:26150153
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Tang H et al. |
Comparative Metabolomic Analysis of the Neuroprotective Effects of Scutellarin and Scutellarein against Ischemic Insult. |
2015 |
PLoS ONE |
pmid:26147971
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Ma X et al. |
Acylation of Antioxidant of Bamboo Leaves with Fatty Acids by Lipase and the Acylated Derivatives' Efficiency in the Inhibition of Acrylamide Formation in Fried Potato Crisps. |
2015 |
PLoS ONE |
pmid:26098744
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Gao R et al. |
Simultaneous determination of oleanolic acid, ursolic acid, quercetin and apigenin in Swertia mussotii Franch by capillary zone electrophoresis with running buffer modifier. |
2015 |
Biomed. Chromatogr. |
pmid:25042239
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Nakamura K et al. |
Effects of Hydroxy Groups in the A-Ring on the Anti-proteasome Activity of Flavone. |
2015 |
Biol. Pharm. Bull. |
pmid:25810454
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Apigenin inhibits pancreatic stellate cell activity in pancreatitis. |
2015 |
J. Surg. Res. |
pmid:25799526
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Liu L et al. |
Characterization of the intestinal absorption of seven flavonoids from the flowers of Trollius chinensis using the Caco-2 cell monolayer model. |
2015 |
PLoS ONE |
pmid:25789809
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Ji P et al. |
Antiviral activity of Paulownia tomentosa against enterovirus 71 of hand, foot, and mouth disease. |
2015 |
Biol. Pharm. Bull. |
pmid:25744451
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Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia. |
2015 |
J Neuroinflammation |
pmid:25600517
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Li KC et al. |
Apigenin-7-glycoside prevents LPS-induced acute lung injury via downregulation of oxidative enzyme expression and protein activation through inhibition of MAPK phosphorylation. |
2015 |
Int J Mol Sci |
pmid:25590301
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Huang H et al. |
effects of natural flavonoids on photosynthetic activity and cell integrity in Microcystis aeruginosa. |
2015 |
Toxins (Basel) |
pmid:25584428
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Shi X et al. |
Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo. |
2015 |
Int. J. Mol. Med. |
pmid:25394920
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Chomicki G et al. |
The velamen protects photosynthetic orchid roots against UV-B damage, and a large dated phylogeny implies multiple gains and losses of this function during the Cenozoic. |
2015 |
New Phytol. |
pmid:25345817
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Chang X et al. |
Protective effect of apigenin on Freund's complete adjuvant-induced arthritis in rats via inhibiting P2X7/NF-κB pathway. |
2015 |
Chem. Biol. Interact. |
pmid:25935278
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Zhang T et al. |
Apigenin attenuates heart injury in lipopolysaccharide-induced endotoxemic model by suppressing sphingosine kinase 1/sphingosine 1-phosphate signaling pathway. |
2015 |
Chem. Biol. Interact. |
pmid:25557508
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In vitro effects of some flavones on human pyruvate kinase isoenzyme M2. |
2015 |
J. Biochem. Mol. Toxicol. |
pmid:25388478
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Yamagata K et al. |
Dietary polyphenols regulate endothelial function and prevent cardiovascular disease. |
2015 |
Nutrition |
pmid:25466651
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Flavonoids suppress human glioblastoma cell growth by inhibiting cell metabolism, migration, and by regulating extracellular matrix proteins and metalloproteinases expression. |
2015 |
Chem. Biol. Interact. |
pmid:26408079
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Screening of a chemical library reveals novel PXR-activating pharmacologic compounds. |
2015 |
Toxicol. Lett. |
pmid:25455453
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Kim SH et al. |
Suppression of AKT Potentiates Synergistic Cytotoxicity of Apigenin with TRAIL in Anaplastic Thyroid Carcinoma Cells. |
2015 |
Anticancer Res. |
pmid:26637867
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Li H et al. |
Separation of vitexin-4″-O-glucoside and vitexin-2″-O-rhamnoside from hawthorn leaves extracts using macroporous resins. |
2015 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:26562804
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Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment. |
2015 |
J. Nat. Prod. |
pmid:26529431
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Olive leaf components apigenin 7-glucoside and luteolin 7-glucoside direct human hematopoietic stem cell differentiation towards erythroid lineage. |
2015 |
Differentiation |
pmid:26299581
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Zhang L et al. |
Apigenin induces autophagic cell death in human papillary thyroid carcinoma BCPAP cells. |
2015 |
Food Funct |
pmid:26292725
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Li W et al. |
Efflux transport of chrysin and apigenin sulfates in HEK293 cells overexpressing SULT1A3: The role of multidrug resistance-associated protein 4 (MRP4/ABCC4). |
2015 |
Biochem. Pharmacol. |
pmid:26291395
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Lin S et al. |
Inhibition of chrysin on xanthine oxidase activity and its inhibition mechanism. |
2015 |
Int. J. Biol. Macromol. |
pmid:26275460
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Seco-ursane-type Triterpenoids from Salvia urmiensis with Apoptosis-inducing Activity. |
2015 |
Planta Med. |
pmid:26252828
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Lee W et al. |
Antiseptic effect of vicenin-2 and scolymoside from Cyclopia subternata (honeybush) in response to HMGB1 as a late sepsis mediator in vitro and in vivo. |
2015 |
Can. J. Physiol. Pharmacol. |
pmid:26243020
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Bao YY et al. |
Inhibiting GLUT-1 expression and PI3K/Akt signaling using apigenin improves the radiosensitivity of laryngeal carcinoma in vivo. |
2015 |
Oncol. Rep. |
pmid:26238658
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Long HP et al. |
Involvenflavones A-F, six new flavonoids with 3'-aryl substituent from Selaginella involven. |
2015 |
Fitoterapia |
pmid:26226107
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Inhibitory Effect of Apigenin on Pharmacokinetics of Venlafaxine in vivo and in vitro. |
2015 |
Pharmacology |
pmid:26202346
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Min JW et al. |
Vitexin reduces hypoxia-ischemia neonatal brain injury by the inhibition of HIF-1alpha in a rat pup model. |
2015 |
Neuropharmacology |
pmid:26187393
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Hong H et al. |
Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein. |
2015 |
Toxicol. Sci. |
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