de Santana Aquino DF et al. |
Anti-hyperalgesic and Anti-inflammatory Activity of Alternanthera Maritima Extract and 2″-O-α-L-rhamnopyranosylvitexin in Mice. |
2015 |
Inflammation |
pmid:26045342
|
Yin Q et al. |
In vitro-assessment of putative antiprogestin activities of phytochemicals and synthetic UV absorbers in human endometrial Ishikawa cells. |
2015 |
Gynecol. Endocrinol. |
pmid:26036805
|
Liu X et al. |
Apigenin inhibits the proliferation and invasion of osteosarcoma cells by suppressing the Wnt/β-catenin signaling pathway. |
2015 |
Oncol. Rep. |
pmid:26035210
|
Supuran CT |
Nanoparticles for controlled release of anti-biofilm agents WO2014130994 (A1): a patent evaluation. |
2015 |
Expert Opin Ther Pat |
pmid:26028186
|
Zhang T et al. |
Apigenin protects blood-brain barrier and ameliorates early brain injury by inhibiting TLR4-mediated inflammatory pathway in subarachnoid hemorrhage rats. |
2015 |
Int. Immunopharmacol. |
pmid:26028151
|
Su ZR et al. |
Discovery of xanthine oxidase inhibitors and/or α-glucosidase inhibitors by carboxyalkyl derivatization based on the flavonoid of apigenin. |
2015 |
Bioorg. Med. Chem. Lett. |
pmid:26022844
|
Boudjelal A et al. |
Antidiabetic Effects of Aqueous Infusions of Artemisia herba-alba and Ajuga iva in Alloxan-Induced Diabetic Rats. |
2015 |
Planta Med. |
pmid:26018915
|
Chang CY et al. |
Apigenin, a natural flavonoid, inhibits glutamate release in the rat hippocampus. |
2015 |
Eur. J. Pharmacol. |
pmid:26007643
|
Zhang X et al. |
Apigenin promotes osteogenic differentiation of human mesenchymal stem cells through JNK and p38 MAPK pathways. |
2015 |
Mol. Cell. Biochem. |
pmid:25994505
|
Wong TY et al. |
The flavone apigenin blocks nuclear translocation of sterol regulatory element-binding protein-2 in the hepatic cells WRL-68. |
2015 |
Br. J. Nutr. |
pmid:25978649
|
Banerjee K et al. |
Probing the potential of apigenin liposomes in enhancing bacterial membrane perturbation and integrity loss. |
2015 |
J Colloid Interface Sci |
pmid:25965432
|
Mastantuono T et al. |
Effects of Citrus Flavonoids Against Microvascular Damage Induced by Hypoperfusion and Reperfusion in Rat Pial Circulation. |
2015 |
Microcirculation |
pmid:25944567
|
Patil RH et al. |
Apigenin inhibits PMA-induced expression of pro-inflammatory cytokines and AP-1 factors in A549 cells. |
2015 |
Mol. Cell. Biochem. |
pmid:25666088
|
Mustapha N et al. |
Compounds isolated from the aerial part of Crataegus azarolus inhibit growth of B16F10 melanoma cells and exert a potent inhibition of the melanin synthesis. |
2015 |
Biomed. Pharmacother. |
pmid:25661350
|
Mascaraque C et al. |
Intestinal anti-inflammatory activity of apigenin K in two rat colitis models induced by trinitrobenzenesulfonic acid and dextran sulphate sodium. |
2015 |
Br. J. Nutr. |
pmid:25654996
|
Costa G et al. |
Flavan hetero-dimers in the Cymbopogon citratus infusion tannin fraction and their contribution to the antioxidant activity. |
2015 |
Food Funct |
pmid:25652784
|
Arango D et al. |
Dietary apigenin reduces LPS-induced expression of miR-155 restoring immune balance during inflammation. |
2015 |
Mol Nutr Food Res |
pmid:25641956
|
Sang Z et al. |
Multifunctional scutellarin-rivastigmine hybrids with cholinergic, antioxidant, biometal chelating and neuroprotective properties for the treatment of Alzheimer's disease. |
2015 |
Bioorg. Med. Chem. |
pmid:25614117
|
Xiong F et al. |
Integrated pharmacokinetics and biodistribution of multiple flavonoid C-glycosides components in rat after oral administration of Abrus mollis extract and correlations with bio-effects. |
2015 |
J Ethnopharmacol |
pmid:25614108
|
Gidaro MC et al. |
Eriocitrin and Apigenin as New Carbonic Anhydrase VA Inhibitors from a Virtual Screening of Calabrian Natural Products. |
2015 |
Planta Med. |
pmid:25590364
|
MarÃa Landete J et al. |
Effect of soaking and fermentation on content of phenolic compounds of soybean (Glycine max cv. Merit) and mung beans (Vigna radiata [L] Wilczek). |
2015 |
Int J Food Sci Nutr |
pmid:25582183
|
Tang H et al. |
Investigation on the interactions of scutellarin and scutellarein with bovine serum albumin using spectroscopic and molecular docking techniques. |
2015 |
Arch. Pharm. Res. |
pmid:25577334
|
Del Turco S et al. |
Synthetic analogues of flavonoids with improved activity against platelet activation and aggregation as novel prototypes of food supplements. |
2015 |
Food Chem |
pmid:25577111
|
Guzelmeric E et al. |
Development and validation of an HPTLC method for apigenin 7-O-glucoside in chamomile flowers and its application for fingerprint discrimination of chamomile-like materials. |
2015 |
J Pharm Biomed Anal |
pmid:25575175
|
Liu W et al. |
Protective effects of apigenin against 1-methyl-4-phenylpyridinium ion‑induced neurotoxicity in PC12 cells. |
2015 |
Int. J. Mol. Med. |
pmid:25573459
|
Li LH et al. |
Apigenin inhibits TGF-β1-induced proliferation and migration of airway smooth muscle cells. |
2015 |
Int J Clin Exp Pathol |
pmid:26722444
|
Pereira C et al. |
Infusions of artichoke and milk thistle represent a good source of phenolic acids and flavonoids. |
2015 |
Food Funct |
pmid:25367590
|
Hu XY et al. |
5-Fluorouracil combined with apigenin enhances anticancer activity through mitochondrial membrane potential (ΔΨm)-mediated apoptosis in hepatocellular carcinoma. |
2015 |
Clin. Exp. Pharmacol. Physiol. |
pmid:25363523
|
Zhu Y et al. |
Apigenin inhibits migration and invasion via modulation of epithelial mesenchymal transition in prostate cancer. |
2015 |
Mol Med Rep |
pmid:25351792
|
Liu J et al. |
Apigenin inhibits HeLa sphere-forming cells through inactivation of casein kinase 2α. |
2015 |
Mol Med Rep |
pmid:25334018
|
Shibamoto T |
A novel gas chromatographic method for determination of malondialdehyde from oxidized DNA. |
2015 |
Methods Mol. Biol. |
pmid:25323498
|
Wu PS et al. |
Luteolin and Apigenin Attenuate 4-Hydroxy-2-Nonenal-Mediated Cell Death through Modulation of UPR, Nrf2-ARE and MAPK Pathways in PC12 Cells. |
2015 |
PLoS ONE |
pmid:26087007
|
Amini R et al. |
Apigenin modulates the expression levels of pro-inflammatory mediators to reduce the human insulin amyloid-induced oxidant damages in SK-N-MC cells. |
2015 |
Hum Exp Toxicol |
pmid:25304968
|
Nakajima A et al. |
A new flavanone and other flavonoids from green perilla leaf extract inhibit nitric oxide production in interleukin 1β-treated hepatocytes. |
2015 |
Biosci. Biotechnol. Biochem. |
pmid:25266050
|
Farkas O et al. |
Polymethoxyflavone Apigenin-Trimethylether Suppresses LPS-Induced Inflammatory Response in Nontransformed Porcine Intestinal Cell Line IPEC-J2. |
2015 |
Oxid Med Cell Longev |
pmid:26180592
|
Chen X et al. |
Effect of scutellarin on the metabolism and pharmacokinetics of clopidogrel in rats. |
2015 |
Biopharm Drug Dispos |
pmid:25256597
|
Shukla S et al. |
Suppression of NF-κB and NF-κB-Regulated Gene Expression by Apigenin through IκBα and IKK Pathway in TRAMP Mice. |
2015 |
PLoS ONE |
pmid:26379052
|
Sun J et al. |
Chemical Constituents and Antibacterial Properties of Indocalamus latifolius McClure Leaves, the Packaging Material for "Zongzi". |
2015 |
Molecules |
pmid:26343625
|
Fang J et al. |
Apigenin inhibits the proliferation of adenoid cystic carcinoma via suppression of glucose transporter-1. |
2015 |
Mol Med Rep |
pmid:26300442
|
Falcone Ferreyra ML et al. |
The Identification of Maize and Arabidopsis Type I FLAVONE SYNTHASEs Links Flavones with Hormones and Biotic Interactions. |
2015 |
Plant Physiol. |
pmid:26269546
|
Cattaneo L et al. |
Anti-Proliferative Effect of Rosmarinus officinalis L. Extract on Human Melanoma A375 Cells. |
2015 |
PLoS ONE |
pmid:26176704
|
Jeon BJ et al. |
Apigenin inhibits indoxyl sulfate-induced endoplasmic reticulum stress and anti-proliferative pathways, CHOP and IL-6/p21, in human renal proximal tubular cells. |
2015 |
Eur Rev Med Pharmacol Sci |
pmid:26166660
|
Zhang Y et al. |
Apigenin induces dermal collagen synthesis via smad2/3 signaling pathway. |
2015 |
Eur J Histochem |
pmid:26150153
|
Tang H et al. |
Comparative Metabolomic Analysis of the Neuroprotective Effects of Scutellarin and Scutellarein against Ischemic Insult. |
2015 |
PLoS ONE |
pmid:26147971
|
Ma X et al. |
Acylation of Antioxidant of Bamboo Leaves with Fatty Acids by Lipase and the Acylated Derivatives' Efficiency in the Inhibition of Acrylamide Formation in Fried Potato Crisps. |
2015 |
PLoS ONE |
pmid:26098744
|
Shiota C et al. |
Flavones Inhibit LPS-Induced Atrogin-1/MAFbx Expression in Mouse C2C12 Skeletal Myotubes. |
2015 |
J. Nutr. Sci. Vitaminol. |
pmid:26052151
|
Dadheech N et al. |
Swertisin an Anti-Diabetic Compound Facilitate Islet Neogenesis from Pancreatic Stem/Progenitor Cells via p-38 MAP Kinase-SMAD Pathway: An In-Vitro and In-Vivo Study. |
2015 |
PLoS ONE |
pmid:26047129
|
Zhang W et al. |
A new and efficient synthesis of 6-O-methylscutellarein, the major metabolite of the natural medicine scutellarin. |
2015 |
Molecules |
pmid:26042857
|
Lee H et al. |
Biosynthesis of Two Flavones, Apigenin and Genkwanin, in Escherichia coli. |
2015 |
J. Microbiol. Biotechnol. |
pmid:25975614
|
Banerjee K and Mandal M |
Oxidative stress triggered by naturally occurring flavone apigenin results in senescence and chemotherapeutic effect in human colorectal cancer cells. |
2015 |
Redox Biol |
pmid:25965143
|
Kumar KK et al. |
Pharmacokinetic drug interactions between apigenin, rutin and paclitaxel mediated by P-glycoprotein in rats. |
2015 |
Eur J Drug Metab Pharmacokinet |
pmid:24871039
|
Shi X et al. |
Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo. |
2015 |
Int. J. Mol. Med. |
pmid:25394920
|
Chomicki G et al. |
The velamen protects photosynthetic orchid roots against UV-B damage, and a large dated phylogeny implies multiple gains and losses of this function during the Cenozoic. |
2015 |
New Phytol. |
pmid:25345817
|
Avelino-Flores Mdel C et al. |
Cytotoxic activity of the methanolic extract of Turnera diffusa Willd on breast cancer cells. |
2015 |
J Med Food |
pmid:25299247
|
Aslan E and Adem S |
In vitro effects of some flavones on human pyruvate kinase isoenzyme M2. |
2015 |
J. Biochem. Mol. Toxicol. |
pmid:25388478
|
Ratajewski M et al. |
Screening of a chemical library reveals novel PXR-activating pharmacologic compounds. |
2015 |
Toxicol. Lett. |
pmid:25455453
|
Sun H et al. |
Decreased Expression of Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Leads to Reduced Glucuronidation of Flavonoids in UGT1A1-Overexpressing HeLa Cells: The Role of Futile Recycling. |
2015 |
J. Agric. Food Chem. |
pmid:26066637
|
An F et al. |
Attenuation of oxidative stress of erythrocytes by the plant-derived flavonoids vitexin and apigenin. |
2015 |
Pharmazie |
pmid:26790189
|
Lin CH et al. |
Thrombin-induced IL-8/CXCL8 release is mediated by CK2, MSK1, and NF-κB pathways in human lung epithelial cells. |
2015 |
Eur. J. Pharmacol. |
pmid:26463037
|
Shi ZH et al. |
Synthesis of scutellarein derivatives to increase biological activity and water solubility. |
2015 |
Bioorg. Med. Chem. |
pmid:26455656
|
Yang X et al. |
Apigenin attenuates myocardial ischemia/reperfusion injury via the inactivation of p38 mitogen‑activated protein kinase. |
2015 |
Mol Med Rep |
pmid:26398147
|
Liu Y et al. |
High-resolution hyaluronidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-necrosis constituents in Chinese plants used to treat snakebite. |
2015 |
Phytochemistry |
pmid:26386983
|
Guimarães CC et al. |
The glycosylated flavonoids vitexin, isovitexin, and quercetrin isolated from Serjania erecta Radlk (Sapindaceae) leaves protect PC12 cells against amyloid-β25-35 peptide-induced toxicity. |
2015 |
Food Chem. Toxicol. |
pmid:26385725
|
Samet I et al. |
Olive leaf components apigenin 7-glucoside and luteolin 7-glucoside direct human hematopoietic stem cell differentiation towards erythroid lineage. |
2015 |
Differentiation |
pmid:26299581
|
Zhang L et al. |
Apigenin induces autophagic cell death in human papillary thyroid carcinoma BCPAP cells. |
2015 |
Food Funct |
pmid:26292725
|
Li W et al. |
Efflux transport of chrysin and apigenin sulfates in HEK293 cells overexpressing SULT1A3: The role of multidrug resistance-associated protein 4 (MRP4/ABCC4). |
2015 |
Biochem. Pharmacol. |
pmid:26291395
|
Hong H et al. |
Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein. |
2015 |
Toxicol. Sci. |
pmid:25349334
|
Zhang CJ et al. |
[Simultaneous determination of four flavone C-glycosides in Phyllostachys edulis leaves by high-performance liquid chromatography with ultraviolet spectrometry]. |
2014 |
Guang Pu Xue Yu Guang Pu Fen Xi |
pmid:25532365
|
Guo H et al. |
Apigenin mediated protection of OGD-evoked neuron-like injury in differentiated PC12 cells. |
2014 |
Neurochem. Res. |
pmid:25208641
|
Wang D et al. |
Scutellarin inhibits high glucose-induced and hypoxia-mimetic agent-induced angiogenic effects in human retinal endothelial cells through reactive oxygen species/hypoxia-inducible factor-1α/vascular endothelial growth factor pathway. |
2014 |
J. Cardiovasc. Pharmacol. |
pmid:25192544
|
Yang X et al. |
Nanosuspension development of scutellarein as an active and rapid orally absorbed precursor of its BCS class IV glycoside scutellarin. |
2014 |
J Pharm Sci |
pmid:25187229
|
Watanabe Y et al. |
Phytotoxic potential of Onopordum acanthium L. (Asteraceae). |
2014 |
Chem. Biodivers. |
pmid:25146768
|
Fang L et al. |
Application of isoabsorption plots generated by high-performance liquid chromatography with diode array detection to the development of multicomponent quantitative analysis of traditional herbal medicines. |
2014 |
J Sep Sci |
pmid:25146493
|
Nisha VM et al. |
Apigenin and quercetin ameliorate mitochondrial alterations by tunicamycin-induced ER stress in 3T3-L1 adipocytes. |
2014 |
Appl. Biochem. Biotechnol. |
pmid:25106896
|
Patil SP et al. |
Neuroprotective and neurotrophic effects of Apigenin and Luteolin in MPTP induced parkinsonism in mice. |
2014 |
Neuropharmacology |
pmid:25087727
|
Jung WW |
Protective effect of apigenin against oxidative stress-induced damage in osteoblastic cells. |
2014 |
Int. J. Mol. Med. |
pmid:24573323
|
Xue HF et al. |
Hepatic, gastric, and intestinal first-pass effects of vitexin in rats. |
2014 |
Pharm Biol |
pmid:24555505
|
Simeonova R et al. |
Protective effects of the apigenin-O/C-diglucoside saponarin from Gypsophila trichotoma on carbone tetrachloride-induced hepatotoxicity in vitro/in vivo in rats. |
2014 |
Phytomedicine |
pmid:24011529
|
Wang F et al. |
Host-guest inclusion system of scutellarein with 2-hydroxypropyl-beta-cyclodextrin: preparation, characterization, and anticancer activity. |
2014 |
J Biomater Sci Polym Ed |
pmid:24555409
|
Wei W et al. |
Effects of vitexin-2"-O-rhamnoside and vitexin-4"-O-glucoside on growth and oxidative stress-induced cell apoptosis of human adipose-derived stem cells. |
2014 |
J. Pharm. Pharmacol. |
pmid:24533889
|
Kumar D and Bhat ZA |
Apigenin 7-glucoside from Stachys tibetica Vatke and its anxiolytic effect in rats. |
2014 |
Phytomedicine |
pmid:24462214
|
Popović M et al. |
The flavonoid apigenin delays forgetting of passive avoidance conditioning in rats. |
2014 |
J. Psychopharmacol. (Oxford) |
pmid:24284476
|
Xu YY et al. |
Apigenin suppresses GLUT-1 and p-AKT expression to enhance the chemosensitivity to cisplatin of laryngeal carcinoma Hep-2 cells: an in vitro study. |
2014 |
Int J Clin Exp Pathol |
pmid:25120770
|
Vamanu E |
Antioxidant properties of mushroom mycelia obtained by batch cultivation and tocopherol content affected by extraction procedures. |
2014 |
Biomed Res Int |
pmid:25110715
|
Tsalkidou EG et al. |
The effects of apigenin on the expression of Fas/FasL apoptotic pathway in warm liver ischemia-reperfusion injury in rats. |
2014 |
Biomed Res Int |
pmid:25110657
|
Warat M et al. |
Chrysin, apigenin and acacetin inhibit tumor necrosis factor-related apoptosis-inducing ligand receptor-1 (TRAIL-R1) on activated RAW264.7 macrophages. |
2014 |
Int J Mol Sci |
pmid:24979133
|
Jiang NH et al. |
Analysis of the transcriptome of Erigeron breviscapus uncovers putative scutellarin and chlorogenic acids biosynthetic genes and genetic markers. |
2014 |
PLoS ONE |
pmid:24956277
|
Nakatsu D et al. |
JNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheet. |
2014 |
Genes Cells |
pmid:24889144
|
Ding SM et al. |
Enhanced bioavailability of apigenin via preparation of a carbon nanopowder solid dispersion. |
2014 |
Int J Nanomedicine |
pmid:24872695
|
Chen H et al. |
Design, synthesis, and characterization of novel apigenin analogues that suppress pancreatic stellate cell proliferation in vitro and associated pancreatic fibrosis in vivo. |
2014 |
Bioorg. Med. Chem. |
pmid:24837156
|
Yang L et al. |
Neuroprotective effects of vitexin by inhibition of NMDA receptors in primary cultures of mouse cerebral cortical neurons. |
2014 |
Mol. Cell. Biochem. |
pmid:24141792
|
Wu DG et al. |
Apigenin potentiates the growth inhibitory effects by IKK-β-mediated NF-κB activation in pancreatic cancer cells. |
2014 |
Toxicol. Lett. |
pmid:24148603
|
Han XJ et al. |
Functional characterization of a Plagiochasma appendiculatum flavone synthase I showing flavanone 2-hydroxylase activity. |
2014 |
FEBS Lett. |
pmid:24859082
|
Seo HS et al. |
Induction of caspase-dependent apoptosis by apigenin by inhibiting STAT3 signaling in HER2-overexpressing MDA-MB-453 breast cancer cells. |
2014 |
Anticancer Res. |
pmid:24922650
|
Lin Z et al. |
In vivo effects of scutellarin on the activities of CYP1A2, CYP2C11, CYP2D1, and CYP3A1/2 by cocktail probe drugs in rats. |
2014 |
Pharmazie |
pmid:25073400
|
Singh PP and Chauhan SM |
Activity-guided isolation of antioxidants from the leaves of Terminalia arjuna. |
2014 |
Nat. Prod. Res. |
pmid:24484080
|
Je HG et al. |
The inhibitory effect of vitexin on the agonist-induced regulation of vascular contractility. |
2014 |
Pharmazie |
pmid:24716414
|
Kim MA et al. |
Apigenin isolated from Daphne genkwa Siebold et Zucc. inhibits 3T3-L1 preadipocyte differentiation through a modulation of mitotic clonal expansion. |
2014 |
Life Sci. |
pmid:24582594
|
Li YR et al. |
[Quality standard study on Vigna radiata]. |
2014 |
Zhongguo Zhong Yao Za Zhi |
pmid:24754176
|
Guedj F et al. |
Prenatal treatment of Down syndrome: a reality? |
2014 |
Curr. Opin. Obstet. Gynecol. |
pmid:24573065
|