Abdelhady MI et al. |
Bioassay-guided isolation and POM analyses of a new immunomodulatory polyphenolic constituent from Callistemon viridiflorus. |
2016 |
Nat. Prod. Res. |
pmid:26156551
|
Veltmann M et al. |
Osmotic Induction of Angiogenic Growth Factor Expression in Human Retinal Pigment Epithelial Cells. |
2016 |
PLoS ONE |
pmid:26800359
|
Chen M et al. |
Apigenin potentiates TRAIL therapy of non-small cell lung cancer via upregulating DR4/DR5 expression in a p53-dependent manner. |
2016 |
Sci Rep |
pmid:27752089
|
Zhang YY et al. |
Enzymatic production of oroxylin A and hispidulin using a liverwort flavone 6-O-methyltransferase. |
2016 |
FEBS Lett. |
pmid:27432544
|
Schuster R et al. |
Cajanus cajan- a source of PPARγ activators leading to anti-inflammatory and cytotoxic effects. |
2016 |
Food Funct |
pmid:27603115
|
Siragusa L et al. |
Comparing Drug Images and Repurposing Drugs with BioGPS and FLAPdock: The Thymidylate Synthase Case. |
2016 |
ChemMedChem |
pmid:27404817
|
He JD et al. |
Vitexin suppresses autophagy to induce apoptosis in hepatocellular carcinoma via activation of the JNK signaling pathway. |
2016 |
Oncotarget |
pmid:27588401
|
Feng X et al. |
Activation of PPARγ by a Natural Flavonoid Modulator, Apigenin Ameliorates Obesity-Related Inflammation Via Regulation of Macrophage Polarization. |
2016 |
EBioMedicine |
pmid:27374313
|
Muhammad AA et al. |
Evaluation of wound healing properties of bioactive aqueous fraction from Moringa oleifera Lam on experimentally induced diabetic animal model. |
2016 |
Drug Des Devel Ther |
pmid:27307703
|
Qin Y et al. |
Apigenin inhibits NF-κB and snail signaling, EMT and metastasis in human hepatocellular carcinoma. |
2016 |
Oncotarget |
pmid:27203387
|
Xie Y et al. |
Preparative Separation and Purification of the Total Flavonoids in Scorzonera austriaca with Macroporous Resins. |
2016 |
Molecules |
pmid:27304948
|
Hu Y et al. |
Synthetic investigation toward apigenin 5-O-glycoside camellianin B as well as the chemical structure revision. |
2016 |
Org. Biomol. Chem. |
pmid:27145917
|
Peng HY et al. |
Apigenin-7-O-β-D-glycoside isolation from the highly copper-tolerant plant Elsholtzia splendens. |
2016 |
J Zhejiang Univ Sci B |
pmid:27256678
|
Hawrył A et al. |
TLC Profiles of Selected Cirsium Species with Chemometrics in Construction of Their Fingerprints. |
2016 |
J Chromatogr Sci |
pmid:27130878
|
Jung UJ et al. |
Apigenin Ameliorates Dyslipidemia, Hepatic Steatosis and Insulin Resistance by Modulating Metabolic and Transcriptional Profiles in the Liver of High-Fat Diet-Induced Obese Mice. |
2016 |
Nutrients |
pmid:27213439
|
Yuan Y et al. |
Scutellarin as a Potential Therapeutic Agent for Microglia-Mediated Neuroinflammation in Cerebral Ischemia. |
2016 |
Neuromolecular Med. |
pmid:27103430
|
Pérez-Montaño F et al. |
RNA-seq analysis of the Rhizobium tropici CIAT 899 transcriptome shows similarities in the activation patterns of symbiotic genes in the presence of apigenin and salt. |
2016 |
BMC Genomics |
pmid:26951045
|
Cardenas H et al. |
Dietary Apigenin Exerts Immune-Regulatory Activity in Vivo by Reducing NF-κB Activity, Halting Leukocyte Infiltration and Restoring Normal Metabolic Function. |
2016 |
Int J Mol Sci |
pmid:26938530
|
GarcÃa-MartÃnez O et al. |
Phenolic Compounds in Extra Virgin Olive Oil Stimulate Human Osteoblastic Cell Proliferation. |
2016 |
PLoS ONE |
pmid:26930190
|
Dong ZX et al. |
An Efficient Chemical Synthesis of Scutellarein: An in Vivo Metabolite of Scutellarin. |
2016 |
Molecules |
pmid:26927039
|
Cao HH et al. |
Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma. |
2016 |
Sci Rep |
pmid:26911838
|
Wu G et al. |
Growth temperature and genotype both play important roles in sorghum grain phenolic composition. |
2016 |
Sci Rep |
pmid:26907726
|
Bridgeman BB et al. |
Inhibition of mTOR by apigenin in UVB-irradiated keratinocytes: A new implication of skin cancer prevention. |
2016 |
Cell. Signal. |
pmid:26876613
|
Verma S et al. |
Hydrophobic Interactions Are a Key to MDM2 Inhibition by Polyphenols as Revealed by Molecular Dynamics Simulations and MM/PBSA Free Energy Calculations. |
2016 |
PLoS ONE |
pmid:26863418
|
Fonseca-Silva F et al. |
Oral Efficacy of Apigenin against Cutaneous Leishmaniasis: Involvement of Reactive Oxygen Species and Autophagy as a Mechanism of Action. |
2016 |
PLoS Negl Trop Dis |
pmid:26862901
|
Zhu Q et al. |
Antinociceptive effects of vitexin in a mouse model of postoperative pain. |
2016 |
Sci Rep |
pmid:26763934
|
Wang W et al. |
Neuroprotective Effect of Scutellarin on Ischemic Cerebral Injury by Down-Regulating the Expression of Angiotensin-Converting Enzyme and AT1 Receptor. |
2016 |
PLoS ONE |
pmid:26730961
|
Lv H et al. |
Isovitexin Exerts Anti-Inflammatory and Anti-Oxidant Activities on Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting MAPK and NF-κB and Activating HO-1/Nrf2 Pathways. |
2016 |
Int. J. Biol. Sci. |
pmid:26722219
|
Asanagi M et al. |
Tributyltin induces G2/M cell cycle arrest via NAD(+)-dependent isocitrate dehydrogenase in human embryonic carcinoma cells. |
2016 |
J Toxicol Sci |
pmid:26961604
|
Ginwala R et al. |
Apigenin, a Natural Flavonoid, Attenuates EAE Severity Through the Modulation of Dendritic Cell and Other Immune Cell Functions. |
2016 |
J Neuroimmune Pharmacol |
pmid:26040501
|
Balez R et al. |
Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer's disease. |
2016 |
Sci Rep |
pmid:27514990
|
Zhu H et al. |
Apigenin induced apoptosis in esophageal carcinoma cells by destruction membrane structures. |
2016 |
Scanning |
pmid:26435325
|
Lin F et al. |
[Inhibitory effect of jianpi-jiedu prescription-contained serum on colorectal cancer SW48 cell proliferation by mTOR-P53-P21 signalling pathway]. |
2016 |
Zhong Nan Da Xue Xue Bao Yi Xue Ban |
pmid:27932756
|
Shu L et al. |
[Effects of apigenin on self-renewal and 
uPAR expression in NCI-H446 cell line]. |
2016 |
Zhong Nan Da Xue Xue Bao Yi Xue Ban |
pmid:27932755
|
Yagishita Y et al. |
Photochromic Properties of 3-Deoxyanthocyanidin Pigments in Nontoxic Solvents. |
2016 |
J. Food Sci. |
pmid:27925261
|
Wakx A et al. |
New in vitro biomarkers to detect toxicity in human placental cells: The example of benzo[A]pyrene. |
2016 |
Toxicol In Vitro |
pmid:26657896
|
Chen L et al. |
Neuroprotective effects of vitexin against isoflurane-induced neurotoxicity by targeting the TRPV1 and NR2B signaling pathways. |
2016 |
Mol Med Rep |
pmid:27878303
|
Lim HS et al. |
Apigetrin from Scutellaria baicalensis Georgi Inhibits Neuroinflammation in BV-2 Microglia and Exerts Neuroprotective Effect in HT22 Hippocampal Cells. |
2016 |
J Med Food |
pmid:27845861
|
Kim A et al. |
Apigenin Reduces Proteasome Inhibition-Induced Neuronal Apoptosis by Suppressing the Cell Death Process. |
2016 |
Neurochem. Res. |
pmid:27473386
|
Das MC et al. |
Attenuation of Pseudomonas aeruginosa biofilm formation by Vitexin: A combinatorial study with azithromycin and gentamicin. |
2016 |
Sci Rep |
pmid:27000525
|
Hakobyan A et al. |
Apigenin inhibits African swine fever virus infection in vitro. |
2016 |
Arch. Virol. |
pmid:27638776
|
Coelho PL et al. |
The flavonoid apigenin from Croton betulaster Mull inhibits proliferation, induces differentiation and regulates the inflammatory profile of glioma cells. |
2016 |
Anticancer Drugs |
pmid:27622606
|
Xiao L et al. |
A new mechanism for increasing the oral bioavailability of scutellarin with Cremophor EL: Activation of MRP3 with concurrent inhibition of MRP2 and BCRP. |
2016 |
Eur J Pharm Sci |
pmid:27586020
|
Zeng L et al. |
Inhibitory Mechanism of Apigenin on α-Glucosidase and Synergy Analysis of Flavonoids. |
2016 |
J. Agric. Food Chem. |
pmid:27581205
|
Erdogan S et al. |
The flavonoid apigenin reduces prostate cancer CD44(+) stem cell survival and migration through PI3K/Akt/NF-κB signaling. |
2016 |
Life Sci. |
pmid:27569589
|
Mendel M et al. |
Modification of abomasum contractility by flavonoids present in ruminants diet: in vitro study. |
2016 |
Animal |
pmid:27534882
|
Huang Y et al. |
Preparation of inclusion complex of apigenin-hydroxypropyl-β-cyclodextrin by using supercritical antisolvent process for dissolution and bioavailability enhancement. |
2016 |
Int J Pharm |
pmid:27515291
|
VeÄeÅ™ová K et al. |
Changes of primary and secondary metabolites in barley plants exposed to CdO nanoparticles. |
2016 |
Environ. Pollut. |
pmid:27503055
|
Qin W et al. |
Apigenin and naringenin ameliorate PKCβII-associated endothelial dysfunction via regulating ROS/caspase-3 and NO pathway in endothelial cells exposed to high glucose. |
2016 |
Vascul. Pharmacol. |
pmid:27473516
|
Aseervatham GS et al. |
Expression pattern of NMDA receptors reveals antiepileptic potential of apigenin 8-C-glucoside and chlorogenic acid in pilocarpine induced epileptic mice. |
2016 |
Biomed. Pharmacother. |
pmid:27470339
|
Salami M et al. |
Inhibitory effect of different fennel (Foeniculum vulgare) samples and their phenolic compounds on formation of advanced glycation products and comparison of antimicrobial and antioxidant activities. |
2016 |
Food Chem |
pmid:27451172
|
Liu L et al. |
Luteolin and apigenin activate the Oct-4/Sox2 signal via NFATc1 in human periodontal ligament cells. |
2016 |
Cell Biol. Int. |
pmid:27449921
|
Pan G et al. |
Total synthesis of 8-(6″-umbelliferyl)-apigenin and its analogs as anti-diabetic reagents. |
2016 |
Eur J Med Chem |
pmid:27448923
|
Chen XJ et al. |
Apigenin inhibits glioma cell growth through promoting microRNA-16 and suppression of BCL-2 and nuclear factor-κB/MMP‑9. |
2016 |
Mol Med Rep |
pmid:27430517
|
Das LK et al. |
Three new acyltyramines from Anisodus luridus Link et Otto (Solanaceae). |
2016 |
Nat. Prod. Res. |
pmid:27406583
|
He X et al. |
Protective role of apigenin in cisplatin-induced renal injury. |
2016 |
Eur. J. Pharmacol. |
pmid:27388142
|
Coombs MR et al. |
Apigenin inhibits the inducible expression of programmed death ligand 1 by human and mouse mammary carcinoma cells. |
2016 |
Cancer Lett. |
pmid:27378243
|
Velikova V et al. |
Physiological significance of isoprenoids and phenylpropanoids in drought response of Arundinoideae species with contrasting habitats and metabolism. |
2016 |
Plant Cell Environ. |
pmid:27351898
|
Cattaneo F et al. |
Flour from Prosopis alba cotyledons: A natural source of nutrient and bioactive phytochemicals. |
2016 |
Food Chem |
pmid:27132827
|
Freitas JV and Gaspar LR |
In vitro photosafety and efficacy screening of apigenin, chrysin and beta-carotene for UVA and VIS protection. |
2016 |
Eur J Pharm Sci |
pmid:27130544
|
Seydi E et al. |
Selective Toxicity of Apigenin on Cancerous Hepatocytes by Directly Targeting their Mitochondria. |
2016 |
Anticancer Agents Med Chem |
pmid:27109019
|
Fang M et al. |
Scutellarin promotes microglia-mediated astrogliosis coupled with improved behavioral function in cerebral ischemia. |
2016 |
Neurochem. Int. |
pmid:27105682
|
Wang X et al. |
Suppression of rat and human androgen biosynthetic enzymes by apigenin: Possible use for the treatment of prostate cancer. |
2016 |
Fitoterapia |
pmid:27102611
|
Dubois N et al. |
Constitutive activation of casein kinase 2 in glioblastomas: Absence of class restriction and broad therapeutic potential. |
2016 |
Int. J. Oncol. |
pmid:27098015
|
Simeonova R et al. |
Antidiabetic and antioxidant effects of saponarin from Gypsophila trichotoma on streptozotocin-induced diabetic normotensive and hypertensive rats. |
2016 |
Phytomedicine |
pmid:27064007
|
Kim BK et al. |
Enhancing oral bioavailability using preparations of apigenin-loaded W/O/W emulsions: In vitro and in vivo evaluations. |
2016 |
Food Chem |
pmid:27041302
|
Jiang Z et al. |
Determination of scutellarin in breviscapine preparations using quantitative proton nuclear magnetic resonance spectroscopy. |
2016 |
J Food Drug Anal |
pmid:28911594
|
Márquez-Flores YK et al. |
Apigenin supplementation protects the development of dextran sulfate sodium-induced murine experimental colitis by inhibiting canonical and non-canonical inflammasome signaling pathways. |
2016 |
J. Nutr. Biochem. |
pmid:27012631
|
Lee HE et al. |
Swertisin, a C-glucosylflavone, ameliorates scopolamine-induced memory impairment in mice with its adenosine A1 receptor antagonistic property. |
2016 |
Behav. Brain Res. |
pmid:26996316
|
Zhu ZY et al. |
Apigenin ameliorates hypertension-induced cardiac hypertrophy and down-regulates cardiac hypoxia inducible factor-lα in rats. |
2016 |
Food Funct |
pmid:26987380
|
Lim W et al. |
Apigenin Reduces Survival of Choriocarcinoma Cells by Inducing Apoptosis via the PI3K/AKT and ERK1/2 MAPK Pathways. |
2016 |
J. Cell. Physiol. |
pmid:26970256
|
Xiong Z et al. |
Mushroom (Agaricus bisporus) polyphenoloxidase inhibited by apigenin: Multi-spectroscopic analyses and computational docking simulation. |
2016 |
Food Chem |
pmid:26948635
|
Fu L et al. |
Mechanism evaluation of the interactions between flavonoids and bovine serum albumin based on multi-spectroscopy, molecular docking and Q-TOF HR-MS analyses. |
2016 |
Food Chem |
pmid:26948600
|
Srinivas NR |
Is the inhibition of the liver uptake and biliary excretion, via transporters, the likely mechanism for the increased exposure of vitexin-2''-O-rhamnoside with bile salts in rats? |
2016 |
Biomed. Chromatogr. |
pmid:26928602
|
Kesavan R et al. |
Gentiana lutea exerts anti-atherosclerotic effects by preventing endothelial inflammation and smooth muscle cell migration. |
2016 |
Nutr Metab Cardiovasc Dis |
pmid:26868432
|
Abugri DA et al. |
In vitro activity of Sorghum bicolor extracts, 3-deoxyanthocyanidins, against Toxoplasma gondii. |
2016 |
Exp. Parasitol. |
pmid:26855040
|
Weng L et al. |
Apigenin reverses depression-like behavior induced by chronic corticosterone treatment in mice. |
2016 |
Eur. J. Pharmacol. |
pmid:26826594
|
Dong ZX et al. |
Design, Synthesis, and Biological Evaluation of Scutellarein Derivatives Based on Scutellarin Metabolic Mechanism In Vivo. |
2016 |
Chem Biol Drug Des |
pmid:26808289
|
Han F et al. |
Application of alkyl polyglycoside surfactant in ultrasonic-assisted extraction followed by macroporous resin enrichment for the separation of vitexin-2″-O-rhamnoside and vitexin from Crataegus pinnatifida leaves. |
2016 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:26807707
|
Yang MH et al. |
A new flavone C-glycoside and a new bibenzyl from Bulbophyllum retusiusculum. |
2016 |
Nat. Prod. Res. |
pmid:26729275
|
Nasr-Bouzaiene N et al. |
Immunomodulatory and cellular antioxidant activities of pure compounds from Teucrium ramosissimum Desf. |
2016 |
Tumour Biol. |
pmid:26692099
|
Zhang S et al. |
Apigenin Attenuates Experimental Autoimmune Myocarditis by Modulating Th1/Th2 Cytokine Balance in Mice. |
2016 |
Inflammation |
pmid:26658748
|
Fan J et al. |
Shear rheology and in-vitro release kinetic study of apigenin from lyotropic liquid crystal. |
2016 |
Int J Pharm |
pmid:26657272
|
Nasr Bouzaiene N et al. |
Effect of apigenin-7-glucoside, genkwanin and naringenin on tyrosinase activity and melanin synthesis in B16F10 melanoma cells. |
2016 |
Life Sci. |
pmid:26656314
|
Romero GB et al. |
Simple low-cost miniaturization approach for pharmaceutical nanocrystals production. |
2016 |
Int J Pharm |
pmid:26642945
|
Basios N et al. |
Apigenin Attenuates Inflammation in Experimentally Induced Acute Pancreatitis-Associated Lung Injury. |
2016 |
J Invest Surg |
pmid:26631908
|
Lee IC and Bae JS |
Anti-inflammatory effects of vicenin-2 and scolymoside on polyphosphate-mediated vascular inflammatory responses. |
2016 |
Inflamm. Res. |
pmid:26621502
|
Lou SN et al. |
Phenolic content, antioxidant activity and effective compounds of kumquat extracted by different solvents. |
2016 |
Food Chem |
pmid:26616917
|
Mostafa NM et al. |
Cytotoxic activity and molecular docking of a novel biflavonoid isolated from Jacaranda acutifolia (Bignoniaceae). |
2016 |
Nat. Prod. Res. |
pmid:26594904
|
Kawamura H et al. |
Ultrasonically enhanced extraction of luteolin and apigenin from the leaves of Perilla frutescens (L.) Britt. using liquid carbon dioxide and ethanol. |
2016 |
Ultrason Sonochem |
pmid:26584980
|
Lee YM et al. |
Inhibition of glutamine utilization sensitizes lung cancer cells to apigenin-induced apoptosis resulting from metabolic and oxidative stress. |
2016 |
Int. J. Oncol. |
pmid:26573871
|
Wang WW et al. |
Scutellarin Alleviates Behavioral Deficits in a Mouse Model of Multiple Sclerosis, Possibly Through Protecting Neural Stem Cells. |
2016 |
J. Mol. Neurosci. |
pmid:26514969
|
Chen C et al. |
Involvement of Bcl-2 Signal Pathway in the Protective Effects of Apigenin on Anoxia/Reoxygenation-induced Myocardium Injury. |
2016 |
J. Cardiovasc. Pharmacol. |
pmid:26466327
|
Rosa SI et al. |
Vitexin reduces neutrophil migration to inflammatory focus by down-regulating pro-inflammatory mediators via inhibition of p38, ERK1/2 and JNK pathway. |
2016 |
Phytomedicine |
pmid:26902402
|
Patil RH et al. |
Anti-Inflammatory Effect of Apigenin on LPS-Induced Pro-Inflammatory Mediators and AP-1 Factors in Human Lung Epithelial Cells. |
2016 |
Inflammation |
pmid:26276128
|
Cochran DB et al. |
Degradable poly(apigenin) polymer inhibits tumor cell adhesion to vascular endothelial cells. |
2016 |
J. Biomed. Mater. Res. Part B Appl. Biomater. |
pmid:26251070
|
Zou H et al. |
Two new flavonoids from Selaginella uncinata. |
2016 |
J Asian Nat Prod Res |
pmid:26238803
|
KubÃnová R et al. |
Anticholinesterase, antioxidant activity and phytochemical investigation into aqueous extracts from five species of Agrimonia genus. |
2016 |
Nat. Prod. Res. |
pmid:26235662
|
Iqbal MK et al. |
Recovery of Chicken Growth Plate by Heat-Shock Protein 90 Inhibitors Epigallocatechin-3-Gallate and Apigenin in Thiram-Induced Tibial Dyschondroplasia. |
2016 |
Avian Dis. |
pmid:27902918
|
Buwa CC et al. |
Apigenin Attenuates β-Receptor-Stimulated Myocardial Injury Via Safeguarding Cardiac Functions and Escalation of Antioxidant Defence System. |
2016 |
Cardiovasc. Toxicol. |
pmid:26186996
|