Kiraly AJ et al. |
Apigenin inhibits COX-2, PGE2, and EP1 and also initiates terminal differentiation in the epidermis of tumor bearing mice. |
2016 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:26802941
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Peng HY et al. |
Apigenin-7-O-β-D-glycoside isolation from the highly copper-tolerant plant Elsholtzia splendens. |
2016 |
J Zhejiang Univ Sci B |
pmid:27256678
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Jung UJ et al. |
Apigenin Ameliorates Dyslipidemia, Hepatic Steatosis and Insulin Resistance by Modulating Metabolic and Transcriptional Profiles in the Liver of High-Fat Diet-Induced Obese Mice. |
2016 |
Nutrients |
pmid:27213439
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Pérez-Montaño F et al. |
RNA-seq analysis of the Rhizobium tropici CIAT 899 transcriptome shows similarities in the activation patterns of symbiotic genes in the presence of apigenin and salt. |
2016 |
BMC Genomics |
pmid:26951045
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Kandhare AD et al. |
Acute and repeated doses (28 days) oral toxicity study of Vicenin-1, a flavonoid glycoside isolated from fenugreek seeds in laboratory mice. |
2016 |
Regul. Toxicol. Pharmacol. |
pmid:27773753
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Song M et al. |
Apigenin protects mice from pneumococcal pneumonia by inhibiting the cytolytic activity of pneumolysin. |
2016 |
Fitoterapia |
pmid:27693741
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Das MC et al. |
Attenuation of Pseudomonas aeruginosa biofilm formation by Vitexin: A combinatorial study with azithromycin and gentamicin. |
2016 |
Sci Rep |
pmid:27000525
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Coombs MR et al. |
Apigenin inhibits the inducible expression of programmed death ligand 1 by human and mouse mammary carcinoma cells. |
2016 |
Cancer Lett. |
pmid:27378243
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Velikova V et al. |
Physiological significance of isoprenoids and phenylpropanoids in drought response of Arundinoideae species with contrasting habitats and metabolism. |
2016 |
Plant Cell Environ. |
pmid:27351898
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Shukla R et al. |
Fabrication of Apigenin loaded gellan gum-chitosan hydrogels (GGCH-HGs) for effective diabetic wound healing. |
2016 |
Int. J. Biol. Macromol. |
pmid:27344952
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Wang Z et al. |
Inhibitory Effect of Apigenin on Losartan Metabolism and CYP2C9 Activity in vitro. |
2016 |
Pharmacology |
pmid:27287328
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Weng L et al. |
Apigenin reverses depression-like behavior induced by chronic corticosterone treatment in mice. |
2016 |
Eur. J. Pharmacol. |
pmid:26826594
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Dong ZX et al. |
Design, Synthesis, and Biological Evaluation of Scutellarein Derivatives Based on Scutellarin Metabolic Mechanism In Vivo. |
2016 |
Chem Biol Drug Des |
pmid:26808289
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Han F et al. |
Application of alkyl polyglycoside surfactant in ultrasonic-assisted extraction followed by macroporous resin enrichment for the separation of vitexin-2″-O-rhamnoside and vitexin from Crataegus pinnatifida leaves. |
2016 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:26807707
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Chen C et al. |
Involvement of Bcl-2 Signal Pathway in the Protective Effects of Apigenin on Anoxia/Reoxygenation-induced Myocardium Injury. |
2016 |
J. Cardiovasc. Pharmacol. |
pmid:26466327
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Liu X et al. |
Apigenin inhibits the proliferation and invasion of osteosarcoma cells by suppressing the Wnt/β-catenin signaling pathway. |
2015 |
Oncol. Rep. |
pmid:26035210
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Supuran CT |
Nanoparticles for controlled release of anti-biofilm agents WO2014130994 (A1): a patent evaluation. |
2015 |
Expert Opin Ther Pat |
pmid:26028186
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Zhang T et al. |
Apigenin protects blood-brain barrier and ameliorates early brain injury by inhibiting TLR4-mediated inflammatory pathway in subarachnoid hemorrhage rats. |
2015 |
Int. Immunopharmacol. |
pmid:26028151
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Su ZR et al. |
Discovery of xanthine oxidase inhibitors and/or α-glucosidase inhibitors by carboxyalkyl derivatization based on the flavonoid of apigenin. |
2015 |
Bioorg. Med. Chem. Lett. |
pmid:26022844
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Boudjelal A et al. |
Antidiabetic Effects of Aqueous Infusions of Artemisia herba-alba and Ajuga iva in Alloxan-Induced Diabetic Rats. |
2015 |
Planta Med. |
pmid:26018915
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Chang CY et al. |
Apigenin, a natural flavonoid, inhibits glutamate release in the rat hippocampus. |
2015 |
Eur. J. Pharmacol. |
pmid:26007643
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Zhang X et al. |
Apigenin promotes osteogenic differentiation of human mesenchymal stem cells through JNK and p38 MAPK pathways. |
2015 |
Mol. Cell. Biochem. |
pmid:25994505
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Wong TY et al. |
The flavone apigenin blocks nuclear translocation of sterol regulatory element-binding protein-2 in the hepatic cells WRL-68. |
2015 |
Br. J. Nutr. |
pmid:25978649
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Banerjee K et al. |
Probing the potential of apigenin liposomes in enhancing bacterial membrane perturbation and integrity loss. |
2015 |
J Colloid Interface Sci |
pmid:25965432
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Mastantuono T et al. |
Effects of Citrus Flavonoids Against Microvascular Damage Induced by Hypoperfusion and Reperfusion in Rat Pial Circulation. |
2015 |
Microcirculation |
pmid:25944567
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Sang ZP et al. |
Design, synthesis, and biological evaluation of scutellarein carbamate derivatives as potential multifunctional agents for the treatment of Alzheimer's disease. |
2015 |
Chem Biol Drug Des |
pmid:25941042
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Seo HS et al. |
Apigenin induces caspase-dependent apoptosis by inhibiting signal transducer and activator of transcription 3 signaling in HER2-overexpressing SKBR3 breast cancer cells. |
2015 |
Mol Med Rep |
pmid:25936427
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Chen YJ et al. |
Scutellarin attenuates endothelium-dependent aasodilation impairment induced by hypoxia reoxygenation, through regulating the PKG signaling pathway in rat coronary artery. |
2015 |
Chin J Nat Med |
pmid:25908623
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Paredes-Gonzalez X et al. |
Induction of NRF2-mediated gene expression by dietary phytochemical flavones apigenin and luteolin. |
2015 |
Biopharm Drug Dispos |
pmid:25904312
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Li Y et al. |
Pharmacokinetics and tissue distribution study of Isovitexin in rats by HPLC-MS/MS. |
2015 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:25902051
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Wang Q et al. |
Inhibition of autophagy ameliorates atherogenic inflammation by augmenting apigenin-induced macrophage apoptosis. |
2015 |
Int. Immunopharmacol. |
pmid:25899084
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Shi T et al. |
[Effect of apigenin on protein expressions of PPARs in liver tissues of rats with nonalcoholic steatohepatitis]. |
2015 |
Zhonghua Gan Zang Bing Za Zhi |
pmid:25880979
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Xu C et al. |
Involvement of CAR and PXR in the transcriptional regulation of CYP2B6 gene expression by ingredients from herbal medicines. |
2015 |
Xenobiotica |
pmid:25869249
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Costa G et al. |
Flavan hetero-dimers in the Cymbopogon citratus infusion tannin fraction and their contribution to the antioxidant activity. |
2015 |
Food Funct |
pmid:25652784
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Arango D et al. |
Dietary apigenin reduces LPS-induced expression of miR-155 restoring immune balance during inflammation. |
2015 |
Mol Nutr Food Res |
pmid:25641956
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Sang Z et al. |
Multifunctional scutellarin-rivastigmine hybrids with cholinergic, antioxidant, biometal chelating and neuroprotective properties for the treatment of Alzheimer's disease. |
2015 |
Bioorg. Med. Chem. |
pmid:25614117
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Xiong F et al. |
Integrated pharmacokinetics and biodistribution of multiple flavonoid C-glycosides components in rat after oral administration of Abrus mollis extract and correlations with bio-effects. |
2015 |
J Ethnopharmacol |
pmid:25614108
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Gidaro MC et al. |
Eriocitrin and Apigenin as New Carbonic Anhydrase VA Inhibitors from a Virtual Screening of Calabrian Natural Products. |
2015 |
Planta Med. |
pmid:25590364
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MarÃa Landete J et al. |
Effect of soaking and fermentation on content of phenolic compounds of soybean (Glycine max cv. Merit) and mung beans (Vigna radiata [L] Wilczek). |
2015 |
Int J Food Sci Nutr |
pmid:25582183
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Tang H et al. |
Investigation on the interactions of scutellarin and scutellarein with bovine serum albumin using spectroscopic and molecular docking techniques. |
2015 |
Arch. Pharm. Res. |
pmid:25577334
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Del Turco S et al. |
Synthetic analogues of flavonoids with improved activity against platelet activation and aggregation as novel prototypes of food supplements. |
2015 |
Food Chem |
pmid:25577111
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Guzelmeric E et al. |
Development and validation of an HPTLC method for apigenin 7-O-glucoside in chamomile flowers and its application for fingerprint discrimination of chamomile-like materials. |
2015 |
J Pharm Biomed Anal |
pmid:25575175
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Liu W et al. |
Protective effects of apigenin against 1-methyl-4-phenylpyridinium ion‑induced neurotoxicity in PC12 cells. |
2015 |
Int. J. Mol. Med. |
pmid:25573459
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Yu XD et al. |
Biological evaluation and molecular docking of baicalin and scutellarin as Helicobacter pylori urease inhibitors. |
2015 |
J Ethnopharmacol |
pmid:25557028
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Yang L et al. |
Enhanced action of apigenin and naringenin combination on estrogen receptor activation in non-malignant colonocytes: implications on sorghum-derived phytoestrogens. |
2015 |
Food Funct |
pmid:25553799
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Zhang S et al. |
Studies on the interaction of apigenin with calf thymus DNA by spectroscopic methods. |
2015 |
Spectrochim Acta A Mol Biomol Spectrosc |
pmid:25459730
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Suh YA et al. |
Inhibition of IL-6/STAT3 axis and targeting Axl and Tyro3 receptor tyrosine kinases by apigenin circumvent taxol resistance in ovarian cancer cells. |
2015 |
Int. J. Oncol. |
pmid:25544427
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Russo D et al. |
Antioxidant activities and quali-quantitative analysis of different Smallanthus sonchifolius [(Poepp. and Endl.) H. Robinson] landrace extracts. |
2015 |
Nat. Prod. Res. |
pmid:25533266
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Djouossi MG et al. |
Antimicrobial and antioxidant flavonoids from the leaves of Oncoba spinosa Forssk. (Salicaceae). |
2015 |
BMC Complement Altern Med |
pmid:25928352
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Heredia-Vieira SC et al. |
Unusual C,O-Fused Glycosylapigenins from Serjania marginata Leaves. |
2015 |
J. Nat. Prod. |
pmid:25517504
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Germanò MP et al. |
Anti-angiogenic activity of Entada africana root. |
2015 |
Nat. Prod. Res. |
pmid:25482106
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Li LH et al. |
Apigenin inhibits TGF-β1-induced proliferation and migration of airway smooth muscle cells. |
2015 |
Int J Clin Exp Pathol |
pmid:26722444
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Lin CH et al. |
Flavones inhibit breast cancer proliferation through the Akt/FOXO3a signaling pathway. |
2015 |
BMC Cancer |
pmid:26675309
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Hasnat MA et al. |
Apigenin Attenuates Melanoma Cell Migration by Inducing Anoikis through Integrin and Focal Adhesion Kinase Inhibition. |
2015 |
Molecules |
pmid:26633318
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Lee JA et al. |
Resveratrol as a Bioenhancer to Improve Anti-Inflammatory Activities of Apigenin. |
2015 |
Nutrients |
pmid:26610561
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Fang M et al. |
Scutellarin regulates microglia-mediated TNC1 astrocytic reaction and astrogliosis in cerebral ischemia in the adult rats. |
2015 |
BMC Neurosci |
pmid:26608466
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Shibamoto T |
A novel gas chromatographic method for determination of malondialdehyde from oxidized DNA. |
2015 |
Methods Mol. Biol. |
pmid:25323498
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Wu PS et al. |
Luteolin and Apigenin Attenuate 4-Hydroxy-2-Nonenal-Mediated Cell Death through Modulation of UPR, Nrf2-ARE and MAPK Pathways in PC12 Cells. |
2015 |
PLoS ONE |
pmid:26087007
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Mangoyi R et al. |
Isolation and characterization of an antifungal compound 5-hydroxy-7,4'-dimethoxyflavone from Combretum zeyheri. |
2015 |
BMC Complement Altern Med |
pmid:26573005
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Amini R et al. |
Apigenin modulates the expression levels of pro-inflammatory mediators to reduce the human insulin amyloid-induced oxidant damages in SK-N-MC cells. |
2015 |
Hum Exp Toxicol |
pmid:25304968
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Nakajima A et al. |
A new flavanone and other flavonoids from green perilla leaf extract inhibit nitric oxide production in interleukin 1β-treated hepatocytes. |
2015 |
Biosci. Biotechnol. Biochem. |
pmid:25266050
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Farkas O et al. |
Polymethoxyflavone Apigenin-Trimethylether Suppresses LPS-Induced Inflammatory Response in Nontransformed Porcine Intestinal Cell Line IPEC-J2. |
2015 |
Oxid Med Cell Longev |
pmid:26180592
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Chen X et al. |
Effect of scutellarin on the metabolism and pharmacokinetics of clopidogrel in rats. |
2015 |
Biopharm Drug Dispos |
pmid:25256597
|
Kim M et al. |
Deglycosylation of isoflavone C-glycosides by newly isolated human intestinal bacteria. |
2015 |
J. Sci. Food Agric. |
pmid:25199800
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Cattaneo L et al. |
Anti-Proliferative Effect of Rosmarinus officinalis L. Extract on Human Melanoma A375 Cells. |
2015 |
PLoS ONE |
pmid:26176704
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Jeon BJ et al. |
Apigenin inhibits indoxyl sulfate-induced endoplasmic reticulum stress and anti-proliferative pathways, CHOP and IL-6/p21, in human renal proximal tubular cells. |
2015 |
Eur Rev Med Pharmacol Sci |
pmid:26166660
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Zhang Y et al. |
Apigenin induces dermal collagen synthesis via smad2/3 signaling pathway. |
2015 |
Eur J Histochem |
pmid:26150153
|
Tang H et al. |
Comparative Metabolomic Analysis of the Neuroprotective Effects of Scutellarin and Scutellarein against Ischemic Insult. |
2015 |
PLoS ONE |
pmid:26147971
|
Ma X et al. |
Acylation of Antioxidant of Bamboo Leaves with Fatty Acids by Lipase and the Acylated Derivatives' Efficiency in the Inhibition of Acrylamide Formation in Fried Potato Crisps. |
2015 |
PLoS ONE |
pmid:26098744
|
Shiota C et al. |
Flavones Inhibit LPS-Induced Atrogin-1/MAFbx Expression in Mouse C2C12 Skeletal Myotubes. |
2015 |
J. Nutr. Sci. Vitaminol. |
pmid:26052151
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Dadheech N et al. |
Swertisin an Anti-Diabetic Compound Facilitate Islet Neogenesis from Pancreatic Stem/Progenitor Cells via p-38 MAP Kinase-SMAD Pathway: An In-Vitro and In-Vivo Study. |
2015 |
PLoS ONE |
pmid:26047129
|
Zhang W et al. |
A new and efficient synthesis of 6-O-methylscutellarein, the major metabolite of the natural medicine scutellarin. |
2015 |
Molecules |
pmid:26042857
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Lee H et al. |
Biosynthesis of Two Flavones, Apigenin and Genkwanin, in Escherichia coli. |
2015 |
J. Microbiol. Biotechnol. |
pmid:25975614
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Banerjee K and Mandal M |
Oxidative stress triggered by naturally occurring flavone apigenin results in senescence and chemotherapeutic effect in human colorectal cancer cells. |
2015 |
Redox Biol |
pmid:25965143
|
Zeng P et al. |
Apigenin Attenuates Atherogenesis through Inducing Macrophage Apoptosis via Inhibition of AKT Ser473 Phosphorylation and Downregulation of Plasminogen Activator Inhibitor-2. |
2015 |
Oxid Med Cell Longev |
pmid:25960827
|
del Cerro P et al. |
Regulatory nodD1 and nodD2 genes of Rhizobium tropici strain CIAT 899 and their roles in the early stages of molecular signaling and host-legume nodulation. |
2015 |
BMC Genomics |
pmid:25880529
|
Long L et al. |
Protective effects of scutellarin on type II diabetes mellitus-induced testicular damages related to reactive oxygen species/Bcl-2/Bax and reactive oxygen species/microcirculation/staving pathway in diabetic rat. |
2015 |
J Diabetes Res |
pmid:25861655
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Lin H et al. |
A new and practical synthetic method for the synthesis of 6-O-methyl-scutellarein: one metabolite of scutellarin in vivo. |
2015 |
Int J Mol Sci |
pmid:25854429
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Kumar KK et al. |
Pharmacokinetic drug interactions between apigenin, rutin and paclitaxel mediated by P-glycoprotein in rats. |
2015 |
Eur J Drug Metab Pharmacokinet |
pmid:24871039
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Qian S et al. |
Apigenin restricts FMDV infection and inhibits viral IRES driven translational activity. |
2015 |
Viruses |
pmid:25835532
|
Kang I et al. |
Effects of Mung Bean (Vigna radiata L.) Ethanol Extracts Decrease Proinflammatory Cytokine-Induced Lipogenesis in the KK-Ay Diabese Mouse Model. |
2015 |
J Med Food |
pmid:25826234
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Liu L et al. |
Effect of luteolin and apigenin on the expression of Oct-4, Sox2, and c-Myc in dental pulp cells with in vitro culture. |
2015 |
Biomed Res Int |
pmid:25815323
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Shi X et al. |
Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo. |
2015 |
Int. J. Mol. Med. |
pmid:25394920
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Chomicki G et al. |
The velamen protects photosynthetic orchid roots against UV-B damage, and a large dated phylogeny implies multiple gains and losses of this function during the Cenozoic. |
2015 |
New Phytol. |
pmid:25345817
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Avelino-Flores Mdel C et al. |
Cytotoxic activity of the methanolic extract of Turnera diffusa Willd on breast cancer cells. |
2015 |
J Med Food |
pmid:25299247
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Yamagata K et al. |
Dietary polyphenols regulate endothelial function and prevent cardiovascular disease. |
2015 |
Nutrition |
pmid:25466651
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Chen RB et al. |
Deep Sequencing Reveals the Effect of MeJA on Scutellarin Biosynthesis in Erigeron breviscapus. |
2015 |
PLoS ONE |
pmid:26656917
|
An F et al. |
Attenuation of oxidative stress of erythrocytes by the plant-derived flavonoids vitexin and apigenin. |
2015 |
Pharmazie |
pmid:26790189
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Kim SH et al. |
Suppression of AKT Potentiates Synergistic Cytotoxicity of Apigenin with TRAIL in Anaplastic Thyroid Carcinoma Cells. |
2015 |
Anticancer Res. |
pmid:26637867
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Yang X et al. |
Apigenin attenuates myocardial ischemia/reperfusion injury via the inactivation of p38 mitogen‑activated protein kinase. |
2015 |
Mol Med Rep |
pmid:26398147
|
Liu Y et al. |
High-resolution hyaluronidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-necrosis constituents in Chinese plants used to treat snakebite. |
2015 |
Phytochemistry |
pmid:26386983
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Guimarães CC et al. |
The glycosylated flavonoids vitexin, isovitexin, and quercetrin isolated from Serjania erecta Radlk (Sapindaceae) leaves protect PC12 cells against amyloid-β25-35 peptide-induced toxicity. |
2015 |
Food Chem. Toxicol. |
pmid:26385725
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Samet I et al. |
Olive leaf components apigenin 7-glucoside and luteolin 7-glucoside direct human hematopoietic stem cell differentiation towards erythroid lineage. |
2015 |
Differentiation |
pmid:26299581
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Zhang L et al. |
Apigenin induces autophagic cell death in human papillary thyroid carcinoma BCPAP cells. |
2015 |
Food Funct |
pmid:26292725
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Li W et al. |
Efflux transport of chrysin and apigenin sulfates in HEK293 cells overexpressing SULT1A3: The role of multidrug resistance-associated protein 4 (MRP4/ABCC4). |
2015 |
Biochem. Pharmacol. |
pmid:26291395
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Lin S et al. |
Inhibition of chrysin on xanthine oxidase activity and its inhibition mechanism. |
2015 |
Int. J. Biol. Macromol. |
pmid:26275460
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Farimani MM et al. |
Seco-ursane-type Triterpenoids from Salvia urmiensis with Apoptosis-inducing Activity. |
2015 |
Planta Med. |
pmid:26252828
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Lee W et al. |
Antiseptic effect of vicenin-2 and scolymoside from Cyclopia subternata (honeybush) in response to HMGB1 as a late sepsis mediator in vitro and in vivo. |
2015 |
Can. J. Physiol. Pharmacol. |
pmid:26243020
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Bao YY et al. |
Inhibiting GLUT-1 expression and PI3K/Akt signaling using apigenin improves the radiosensitivity of laryngeal carcinoma in vivo. |
2015 |
Oncol. Rep. |
pmid:26238658
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Long HP et al. |
Involvenflavones A-F, six new flavonoids with 3'-aryl substituent from Selaginella involven. |
2015 |
Fitoterapia |
pmid:26226107
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