Gao Y et al. |
Hepatic, gastric and intestinal first-pass effects of vitexin-2''-O-rhamnoside in rats by ultra-high-performance liquid chromatography. |
2016 |
Biomed. Chromatogr. |
pmid:26031900
|
Kiraly AJ et al. |
Apigenin inhibits COX-2, PGE2, and EP1 and also initiates terminal differentiation in the epidermis of tumor bearing mice. |
2016 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:26802941
|
Veltmann M et al. |
Osmotic Induction of Angiogenic Growth Factor Expression in Human Retinal Pigment Epithelial Cells. |
2016 |
PLoS ONE |
pmid:26800359
|
Hu W et al. |
Apigenin-7-O-β-D-glucuronide inhibits LPS-induced inflammation through the inactivation of AP-1 and MAPK signaling pathways in RAW 264.7 macrophages and protects mice against endotoxin shock. |
2016 |
Food Funct |
pmid:26750400
|
Brunschwig C et al. |
Chemical Composition and Antioxidant Activity of Euterpe oleracea Roots and Leaflets. |
2016 |
Int J Mol Sci |
pmid:28036089
|
Tsaroucha AK et al. |
Intraperitoneal administration of apigenin in liver ischemia/reperfusion injury protective effects. |
2016 |
Saudi J Gastroenterol |
pmid:27976636
|
Hwang SH et al. |
Simultaneous Ultra Performance Liquid Chromatography Determination and Antioxidant Activity of Linarin, Luteolin, Chlorogenic Acid and Apigenin in Different Parts of Compositae Species. |
2016 |
Molecules |
pmid:27886116
|
Lee SW et al. |
Alpha B-Crystallin Protects Rat Articular Chondrocytes against Casein Kinase II Inhibition-Induced Apoptosis. |
2016 |
PLoS ONE |
pmid:27851782
|
BasÃlio N et al. |
Analogs of Natural 3-Deoxyanthocyanins: O-Glucosides of the 4',7-Dihydroxyflavylium Ion and the Deep Influence of Glycosidation on Color. |
2016 |
Int J Mol Sci |
pmid:27775619
|
Chen M et al. |
Apigenin potentiates TRAIL therapy of non-small cell lung cancer via upregulating DR4/DR5 expression in a p53-dependent manner. |
2016 |
Sci Rep |
pmid:27752089
|
Schuster R et al. |
Cajanus cajan- a source of PPARγ activators leading to anti-inflammatory and cytotoxic effects. |
2016 |
Food Funct |
pmid:27603115
|
He JD et al. |
Vitexin suppresses autophagy to induce apoptosis in hepatocellular carcinoma via activation of the JNK signaling pathway. |
2016 |
Oncotarget |
pmid:27588401
|
Qin Y et al. |
Apigenin inhibits NF-κB and snail signaling, EMT and metastasis in human hepatocellular carcinoma. |
2016 |
Oncotarget |
pmid:27203387
|
Hu Y et al. |
Synthetic investigation toward apigenin 5-O-glycoside camellianin B as well as the chemical structure revision. |
2016 |
Org. Biomol. Chem. |
pmid:27145917
|
Hawrył A et al. |
TLC Profiles of Selected Cirsium Species with Chemometrics in Construction of Their Fingerprints. |
2016 |
J Chromatogr Sci |
pmid:27130878
|
Yuan Y et al. |
Scutellarin as a Potential Therapeutic Agent for Microglia-Mediated Neuroinflammation in Cerebral Ischemia. |
2016 |
Neuromolecular Med. |
pmid:27103430
|
Pérez-Montaño F et al. |
RNA-seq analysis of the Rhizobium tropici CIAT 899 transcriptome shows similarities in the activation patterns of symbiotic genes in the presence of apigenin and salt. |
2016 |
BMC Genomics |
pmid:26951045
|
Cardenas H et al. |
Dietary Apigenin Exerts Immune-Regulatory Activity in Vivo by Reducing NF-κB Activity, Halting Leukocyte Infiltration and Restoring Normal Metabolic Function. |
2016 |
Int J Mol Sci |
pmid:26938530
|
GarcÃa-MartÃnez O et al. |
Phenolic Compounds in Extra Virgin Olive Oil Stimulate Human Osteoblastic Cell Proliferation. |
2016 |
PLoS ONE |
pmid:26930190
|
Dong ZX et al. |
An Efficient Chemical Synthesis of Scutellarein: An in Vivo Metabolite of Scutellarin. |
2016 |
Molecules |
pmid:26927039
|
Cao HH et al. |
Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma. |
2016 |
Sci Rep |
pmid:26911838
|
Wu G et al. |
Growth temperature and genotype both play important roles in sorghum grain phenolic composition. |
2016 |
Sci Rep |
pmid:26907726
|
Bridgeman BB et al. |
Inhibition of mTOR by apigenin in UVB-irradiated keratinocytes: A new implication of skin cancer prevention. |
2016 |
Cell. Signal. |
pmid:26876613
|
Verma S et al. |
Hydrophobic Interactions Are a Key to MDM2 Inhibition by Polyphenols as Revealed by Molecular Dynamics Simulations and MM/PBSA Free Energy Calculations. |
2016 |
PLoS ONE |
pmid:26863418
|
Fonseca-Silva F et al. |
Oral Efficacy of Apigenin against Cutaneous Leishmaniasis: Involvement of Reactive Oxygen Species and Autophagy as a Mechanism of Action. |
2016 |
PLoS Negl Trop Dis |
pmid:26862901
|
Zhu Q et al. |
Antinociceptive effects of vitexin in a mouse model of postoperative pain. |
2016 |
Sci Rep |
pmid:26763934
|
Wang W et al. |
Neuroprotective Effect of Scutellarin on Ischemic Cerebral Injury by Down-Regulating the Expression of Angiotensin-Converting Enzyme and AT1 Receptor. |
2016 |
PLoS ONE |
pmid:26730961
|
Lv H et al. |
Isovitexin Exerts Anti-Inflammatory and Anti-Oxidant Activities on Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting MAPK and NF-κB and Activating HO-1/Nrf2 Pathways. |
2016 |
Int. J. Biol. Sci. |
pmid:26722219
|
Cai M et al. |
Apigenin-7-O-β-D-(-6''-p-coumaroyl)-Glucopyranoside Treatment Elicits Neuroprotective Effect against Experimental Ischemic Stroke. |
2016 |
Int. J. Biol. Sci. |
pmid:26722216
|
Tian X et al. |
Delineation of Platelet Activation Pathway of Scutellarein Revealed Its Intracellular Target as Protein Kinase C. |
2016 |
Biol. Pharm. Bull. |
pmid:26581323
|
Asanagi M et al. |
Tributyltin induces G2/M cell cycle arrest via NAD(+)-dependent isocitrate dehydrogenase in human embryonic carcinoma cells. |
2016 |
J Toxicol Sci |
pmid:26961604
|
Ginwala R et al. |
Apigenin, a Natural Flavonoid, Attenuates EAE Severity Through the Modulation of Dendritic Cell and Other Immune Cell Functions. |
2016 |
J Neuroimmune Pharmacol |
pmid:26040501
|
Balez R et al. |
Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer's disease. |
2016 |
Sci Rep |
pmid:27514990
|
Zhu H et al. |
Apigenin induced apoptosis in esophageal carcinoma cells by destruction membrane structures. |
2016 |
Scanning |
pmid:26435325
|
Pápay ZE et al. |
Development of oral site-specific pellets containing flavonoid extract with antioxidant activity. |
2016 |
Eur J Pharm Sci |
pmid:27989856
|
Lin F et al. |
[Inhibitory effect of jianpi-jiedu prescription-contained serum on colorectal cancer SW48 cell proliferation by mTOR-P53-P21 signalling pathway]. |
2016 |
Zhong Nan Da Xue Xue Bao Yi Xue Ban |
pmid:27932756
|
Shu L et al. |
[Effects of apigenin on self-renewal and 
uPAR expression in NCI-H446 cell line]. |
2016 |
Zhong Nan Da Xue Xue Bao Yi Xue Ban |
pmid:27932755
|
Yagishita Y et al. |
Photochromic Properties of 3-Deoxyanthocyanidin Pigments in Nontoxic Solvents. |
2016 |
J. Food Sci. |
pmid:27925261
|
Kandhare AD et al. |
Acute and repeated doses (28 days) oral toxicity study of Vicenin-1, a flavonoid glycoside isolated from fenugreek seeds in laboratory mice. |
2016 |
Regul. Toxicol. Pharmacol. |
pmid:27773753
|
Song M et al. |
Apigenin protects mice from pneumococcal pneumonia by inhibiting the cytolytic activity of pneumolysin. |
2016 |
Fitoterapia |
pmid:27693741
|
He M et al. |
A review on the pharmacological effects of vitexin and isovitexin. |
2016 |
Fitoterapia |
pmid:27693342
|
Dai J et al. |
Downregulation of NEDD9 by apigenin suppresses migration, invasion, and metastasis of colorectal cancer cells. |
2016 |
Toxicol. Appl. Pharmacol. |
pmid:27664007
|
Mudge EM et al. |
Single-Laboratory Validation for the Determination of Flavonoids in Hawthorn Leaves and Finished Products by LC-UV. |
2016 |
Planta Med. |
pmid:27776376
|
Whitehouse S et al. |
Resveratrol, piperine and apigenin differ in their NADPH-oxidase inhibitory and reactive oxygen species-scavenging properties. |
2016 |
Phytomedicine |
pmid:27765370
|
Li Q et al. |
Scutellarin attenuates vasospasm through the Erk5-KLF2-eNOS pathway after subarachnoid hemorrhage in rats. |
2016 |
J Clin Neurosci |
pmid:27742373
|
Das MC et al. |
Attenuation of Pseudomonas aeruginosa biofilm formation by Vitexin: A combinatorial study with azithromycin and gentamicin. |
2016 |
Sci Rep |
pmid:27000525
|
Zhao S et al. |
Scutellarin inhibits RANKL-mediated osteoclastogenesis and titanium particle-induced osteolysis via suppression of NF-κB and MAPK signaling pathway. |
2016 |
Int. Immunopharmacol. |
pmid:27728897
|
Hakobyan A et al. |
Apigenin inhibits African swine fever virus infection in vitro. |
2016 |
Arch. Virol. |
pmid:27638776
|
Coelho PL et al. |
The flavonoid apigenin from Croton betulaster Mull inhibits proliferation, induces differentiation and regulates the inflammatory profile of glioma cells. |
2016 |
Anticancer Drugs |
pmid:27622606
|
Xiao L et al. |
A new mechanism for increasing the oral bioavailability of scutellarin with Cremophor EL: Activation of MRP3 with concurrent inhibition of MRP2 and BCRP. |
2016 |
Eur J Pharm Sci |
pmid:27586020
|
Zeng L et al. |
Inhibitory Mechanism of Apigenin on α-Glucosidase and Synergy Analysis of Flavonoids. |
2016 |
J. Agric. Food Chem. |
pmid:27581205
|
Erdogan S et al. |
The flavonoid apigenin reduces prostate cancer CD44(+) stem cell survival and migration through PI3K/Akt/NF-κB signaling. |
2016 |
Life Sci. |
pmid:27569589
|
Mendel M et al. |
Modification of abomasum contractility by flavonoids present in ruminants diet: in vitro study. |
2016 |
Animal |
pmid:27534882
|
Huang Y et al. |
Preparation of inclusion complex of apigenin-hydroxypropyl-β-cyclodextrin by using supercritical antisolvent process for dissolution and bioavailability enhancement. |
2016 |
Int J Pharm |
pmid:27515291
|
VeÄeÅ™ová K et al. |
Changes of primary and secondary metabolites in barley plants exposed to CdO nanoparticles. |
2016 |
Environ. Pollut. |
pmid:27503055
|
Shukla R et al. |
Fabrication of Apigenin loaded gellan gum-chitosan hydrogels (GGCH-HGs) for effective diabetic wound healing. |
2016 |
Int. J. Biol. Macromol. |
pmid:27344952
|
Wang Z et al. |
Inhibitory Effect of Apigenin on Losartan Metabolism and CYP2C9 Activity in vitro. |
2016 |
Pharmacology |
pmid:27287328
|
Choi S et al. |
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo. |
2016 |
Int. J. Mol. Med. |
pmid:27279007
|
Hlila MB et al. |
Characterisation of phenolic antioxidants in Scabiosa arenaria flowers by LC-ESI-MS/MS and NMR. |
2016 |
J. Pharm. Pharmacol. |
pmid:27230582
|
Terpinc P et al. |
LC-MS analysis of phenolic compounds and antioxidant activity of buckwheat at different stages of malting. |
2016 |
Food Chem |
pmid:27211614
|
Kandhare AD et al. |
Development and validation of HPLC method for vicenin-1 isolated from fenugreek seeds in rat plasma: application to pharmacokinetic, tissue distribution and excretion studies. |
2016 |
Pharm Biol |
pmid:27181500
|
Liu M et al. |
Rapid screening of transferrin-binders in the flowers of Bauhinia blakeana Dunn by on-line high-performance liquid chromatography-diode-array detector-electrospray ionization-ion-trap-time-of-flight-mass spectrometry-transferrin-fluorescence detection system. |
2016 |
J Chromatogr A |
pmid:27178150
|
Karamese M et al. |
Anti-oxidant and anti-inflammatory effects of apigenin in a rat model of sepsis: an immunological, biochemical, and histopathological study. |
2016 |
Immunopharmacol Immunotoxicol |
pmid:27144896
|
Huang C et al. |
Chrysin, Abundant in Morinda citrifolia Fruit Water-EtOAc Extracts, Combined with Apigenin Synergistically Induced Apoptosis and Inhibited Migration in Human Breast and Liver Cancer Cells. |
2016 |
J. Agric. Food Chem. |
pmid:27137679
|
Cattaneo F et al. |
Flour from Prosopis alba cotyledons: A natural source of nutrient and bioactive phytochemicals. |
2016 |
Food Chem |
pmid:27132827
|
Freitas JV and Gaspar LR |
In vitro photosafety and efficacy screening of apigenin, chrysin and beta-carotene for UVA and VIS protection. |
2016 |
Eur J Pharm Sci |
pmid:27130544
|
Seydi E et al. |
Selective Toxicity of Apigenin on Cancerous Hepatocytes by Directly Targeting their Mitochondria. |
2016 |
Anticancer Agents Med Chem |
pmid:27109019
|
Fang M et al. |
Scutellarin promotes microglia-mediated astrogliosis coupled with improved behavioral function in cerebral ischemia. |
2016 |
Neurochem. Int. |
pmid:27105682
|
Wang X et al. |
Suppression of rat and human androgen biosynthetic enzymes by apigenin: Possible use for the treatment of prostate cancer. |
2016 |
Fitoterapia |
pmid:27102611
|
Dubois N et al. |
Constitutive activation of casein kinase 2 in glioblastomas: Absence of class restriction and broad therapeutic potential. |
2016 |
Int. J. Oncol. |
pmid:27098015
|
Simeonova R et al. |
Antidiabetic and antioxidant effects of saponarin from Gypsophila trichotoma on streptozotocin-induced diabetic normotensive and hypertensive rats. |
2016 |
Phytomedicine |
pmid:27064007
|
Kim BK et al. |
Enhancing oral bioavailability using preparations of apigenin-loaded W/O/W emulsions: In vitro and in vivo evaluations. |
2016 |
Food Chem |
pmid:27041302
|
Jiang Z et al. |
Determination of scutellarin in breviscapine preparations using quantitative proton nuclear magnetic resonance spectroscopy. |
2016 |
J Food Drug Anal |
pmid:28911594
|
Han F et al. |
Application of alkyl polyglycoside surfactant in ultrasonic-assisted extraction followed by macroporous resin enrichment for the separation of vitexin-2″-O-rhamnoside and vitexin from Crataegus pinnatifida leaves. |
2016 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:26807707
|
Ren B et al. |
Apigenin and naringenin regulate glucose and lipid metabolism, and ameliorate vascular dysfunction in type 2 diabetic rats. |
2016 |
Eur. J. Pharmacol. |
pmid:26801071
|
Dos Santos KC et al. |
Passiflora actinia hydroalcoholic extract and its major constituent, isovitexin, are neuroprotective against glutamate-induced cell damage in mice hippocampal slices. |
2016 |
J. Pharm. Pharmacol. |
pmid:26800497
|
Luan RL et al. |
Protective Effects of Apigenin Against Paraquat-Induced Acute Lung Injury in Mice. |
2016 |
Inflammation |
pmid:26782361
|
Steuck M et al. |
Food Polyphenol Apigenin Inhibits the Cytochrome P450 Monoxygenase Branch of the Arachidonic Acid Cascade. |
2016 |
J. Agric. Food Chem. |
pmid:27933871
|
Wang Z et al. |
Scutellarin protects cardiomyocyte ischemia-reperfusion injury by reducing apoptosis and oxidative stress. |
2016 |
Life Sci. |
pmid:26775564
|
Ku SK and Bae JS |
Vicenin-2 and scolymoside inhibit high-glucose-induced vascular inflammation in vitro and in vivo. |
2016 |
Can. J. Physiol. Pharmacol. |
pmid:26766560
|
Hou K et al. |
Ionic liquids-lithium salts pretreatment followed by ultrasound-assisted extraction of vitexin-4″-O-glucoside, vitexin-2″-O-rhamnoside and vitexin from Phyllostachys edulis leaves. |
2016 |
J Chromatogr A |
pmid:26763300
|
Schmidt J |
Negative ion electrospray high-resolution tandem mass spectrometry of polyphenols. |
2016 |
J Mass Spectrom |
pmid:26757070
|
Yang MH et al. |
A new flavone C-glycoside and a new bibenzyl from Bulbophyllum retusiusculum. |
2016 |
Nat. Prod. Res. |
pmid:26729275
|
Nasr-Bouzaiene N et al. |
Immunomodulatory and cellular antioxidant activities of pure compounds from Teucrium ramosissimum Desf. |
2016 |
Tumour Biol. |
pmid:26692099
|
Zhang S et al. |
Apigenin Attenuates Experimental Autoimmune Myocarditis by Modulating Th1/Th2 Cytokine Balance in Mice. |
2016 |
Inflammation |
pmid:26658748
|
Fan J et al. |
Shear rheology and in-vitro release kinetic study of apigenin from lyotropic liquid crystal. |
2016 |
Int J Pharm |
pmid:26657272
|
Nasr Bouzaiene N et al. |
Effect of apigenin-7-glucoside, genkwanin and naringenin on tyrosinase activity and melanin synthesis in B16F10 melanoma cells. |
2016 |
Life Sci. |
pmid:26656314
|
Romero GB et al. |
Simple low-cost miniaturization approach for pharmaceutical nanocrystals production. |
2016 |
Int J Pharm |
pmid:26642945
|
Basios N et al. |
Apigenin Attenuates Inflammation in Experimentally Induced Acute Pancreatitis-Associated Lung Injury. |
2016 |
J Invest Surg |
pmid:26631908
|
Lee IC and Bae JS |
Anti-inflammatory effects of vicenin-2 and scolymoside on polyphosphate-mediated vascular inflammatory responses. |
2016 |
Inflamm. Res. |
pmid:26621502
|
Lou SN et al. |
Phenolic content, antioxidant activity and effective compounds of kumquat extracted by different solvents. |
2016 |
Food Chem |
pmid:26616917
|
Guimarães R et al. |
Wild Roman chamomile extracts and phenolic compounds: enzymatic assays and molecular modelling studies with VEGFR-2 tyrosine kinase. |
2016 |
Food Funct |
pmid:26446815
|
Li R et al. |
Apigenin ameliorates chronic mild stress-induced depressive behavior by inhibiting interleukin-1β production and NLRP3 inflammasome activation in the rat brain. |
2016 |
Behav. Brain Res. |
pmid:26416673
|
Pápay ZE et al. |
Comparative evaluation of the effect of cyclodextrins and pH on aqueous solubility of apigenin. |
2016 |
J Pharm Biomed Anal |
pmid:26363816
|
Venditti A et al. |
Phytochemical analysis of Achillea ligustica All. from Lipari Island (Aeolian Islands). |
2016 |
Nat. Prod. Res. |
pmid:26327332
|
Patil RH et al. |
Anti-Inflammatory Effect of Apigenin on LPS-Induced Pro-Inflammatory Mediators and AP-1 Factors in Human Lung Epithelial Cells. |
2016 |
Inflammation |
pmid:26276128
|
Cochran DB et al. |
Degradable poly(apigenin) polymer inhibits tumor cell adhesion to vascular endothelial cells. |
2016 |
J. Biomed. Mater. Res. Part B Appl. Biomater. |
pmid:26251070
|
Zou H et al. |
Two new flavonoids from Selaginella uncinata. |
2016 |
J Asian Nat Prod Res |
pmid:26238803
|
KubÃnová R et al. |
Anticholinesterase, antioxidant activity and phytochemical investigation into aqueous extracts from five species of Agrimonia genus. |
2016 |
Nat. Prod. Res. |
pmid:26235662
|
Iqbal MK et al. |
Recovery of Chicken Growth Plate by Heat-Shock Protein 90 Inhibitors Epigallocatechin-3-Gallate and Apigenin in Thiram-Induced Tibial Dyschondroplasia. |
2016 |
Avian Dis. |
pmid:27902918
|