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2018 |
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Apigenin loaded nanoparticle delayed development of hepatocellular carcinoma in rats. |
2018 |
Nanomedicine |
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2018 |
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2018 |
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Apigenin reduces the Toll-like receptor-4-dependent activation of NF-κB by suppressing the Akt, mTOR, JNK, and p38-MAPK. |
2018 |
Naunyn Schmiedebergs Arch. Pharmacol. |
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2018 |
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2018 |
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2018 |
Mol Plant |
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2018 |
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Experimental and computational approaches to reveal the potential of Ficus deltoidea leaves extract as α-amylase inhibitor. |
2018 |
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Apigenin Retards Atherogenesis by Promoting ABCA1-Mediated Cholesterol Efflux and Suppressing Inflammation. |
2018 |
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Apigenin Suppresses the IL-1β-Induced Expression of the Urokinase-Type Plasminogen Activator Receptor by Inhibiting MAPK-Mediated AP-1 and NF-κB Signaling in Human Bladder Cancer T24 Cells. |
2018 |
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Scutellarin enhances osteoblast proliferation and function via NF-κB-mediated CXCR4 induction. |
2018 |
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Traversal of the Blood-Brain Barrier by Cleavable l-Lysine Conjugates of Apigenin. |
2018 |
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The Inhibitory Effect of Flavonoid Aglycones on the Metabolic Activity of CYP3A4 Enzyme. |
2018 |
Molecules |
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Structural profile of soluble and bound phenolic compounds in teff (Eragrostis tef) reveals abundance of distinctly different flavones in white and brown varieties. |
2018 |
Food Chem |
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CE-DAD Determination of Scutellarein and Caffeic Acid in Abelia triflora Crude Extract. |
2018 |
J Chromatogr Sci |
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Vitexin reverses the autophagy dysfunction to attenuate MCAO-induced cerebral ischemic stroke via mTOR/Ulk1 pathway. |
2018 |
Biomed. Pharmacother. |
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2018 |
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2018 |
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2018 |
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Grewia tiliaefolia and its active compound vitexin regulate the expression of glutamate transporters and protect Neuro-2a cells from glutamate toxicity. |
2018 |
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2018 |
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Beneficial Effects of Different Flavonoids on Vascular and Renal Function in L-NAME Hypertensive Rats. |
2018 |
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Scutellarin Mitigates Aβ-Induced Neurotoxicity and Improves Behavior Impairments in AD Mice. |
2018 |
Molecules |
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The flavonoid compound apigenin prevents colonic inflammation and motor dysfunctions associated with high fat diet-induced obesity. |
2018 |
PLoS ONE |
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Application of an advanced and wide scope non-target screening workflow with LC-ESI-QTOF-MS and chemometrics for the classification of the Greek olive oil varieties. |
2018 |
Food Chem |
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Apigenin enhances the antitumor effects of cetuximab in nasopharyngeal carcinoma by inhibiting EGFR signaling. |
2018 |
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Vitexin protects dopaminergic neurons in MPTP-induced Parkinson's disease through PI3K/Akt signaling pathway. |
2018 |
Drug Des Devel Ther |
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Dose- and time-dependent pharmacokinetics of apigenin trimethyl ether. |
2018 |
Eur J Pharm Sci |
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Vitexin inhibits Aβ induced toxicity in Neuro-2a cells by augmenting Nrf-2/HO-1 dependent antioxidant pathway and regulating lipid homeostasis by the activation of LXR-α. |
2018 |
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Development and characterization of a green procedure for apigenin extraction from Scutellaria barbata D. Don. |
2018 |
Food Chem |
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Flavonoids from Trollius europaeus flowers and evaluation of their biological activity. |
2018 |
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Pharmacological Effects of Scutellarin, An Active Component of Genus Scutellaria and Erigeron: A Systematic Review. |
2018 |
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Comparison of flavonoids and isoflavonoids to inhibit rat and human 11β-hydroxysteroid dehydrogenase 1 and 2. |
2018 |
Steroids |
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Pharmacokinetic comparisons of six components from raw and vinegar-processed Daphne genkwa aqueous extracts following oral administration in rats by employing UHPLC-MS/MS approaches. |
2018 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
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Swertisin ameliorates diabetes by triggering pancreatic progenitors for islet neogenesis in Streptozotocin treated BALB/c mice. |
2018 |
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2018 |
Eur. J. Clin. Invest. |
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Synthesis of Scutellarein Derivatives with a Long Aliphatic Chain and Their Biological Evaluation against Human Cancer Cells. |
2018 |
Molecules |
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Vitexin induces G2/M‑phase arrest and apoptosis via Akt/mTOR signaling pathway in human glioblastoma cells. |
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Scutellarin alleviates lipopolysaccharide-induced cognitive deficits in the rat: Insights into underlying mechanisms. |
2018 |
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2018 |
Cancer Lett. |
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Vitexin inhibits inflammation in murine ovalbumin-induced allergic asthma. |
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Pharmacokinetic comparison of seven major bioactive components in normal and depression model rats after oral administration of Baihe Zhimu decoction by liquid chromatography-tandem mass spectrometry. |
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J Pharm Biomed Anal |
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Scaffold Hopping Strategy for the Design, Synthesis and Biological Activity Evaluation of Novel Hexacyclic Scutellarein Derivatives with a 1,3-Oxazine Ring Fused at A-ring. |
2018 |
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2018 |
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Flavonoids of Alcea rosea L. and their immune stimulant, antioxidant and cytotoxic activities on hepatocellular carcinoma HepG-2 cell line. |
2018 |
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Phytochemical constituents and antioxidant activity of Echinops albicaulis. |
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Multiple pharmacological approaches on Fibigia eriocarpa extracts by in vitro and computational assays. |
2018 |
Fundam Clin Pharmacol |
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A systematic review on phenolic compounds in Passiflora plants: Exploring biodiversity for food, nutrition, and popular medicine. |
2018 |
Crit Rev Food Sci Nutr |
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UPLC-Orbitrap-MS/MS combined with chemometrics establishes variations in chemical components in green tea from Yunnan and Hunan origins. |
2018 |
Food Chem |
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Interactions between erythromycin, flunixin meglumine, levamisole and plant secondary metabolites towards bovine gastrointestinal motility-in vitro study. |
2018 |
J. Vet. Pharmacol. Ther. |
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Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects. |
2018 |
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Zornia latifolia: a smart drug being adulterated by Stylosanthes guianensis. |
2018 |
Int. J. Legal Med. |
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LC-MS/MS method for the simultaneous quantification of luteolin, wedelolactone and apigenin in mice plasma using hansen solubility parameters for liquid-liquid extraction: Application to pharmacokinetics of Eclipta alba chloroform fraction. |
2018 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
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A metabolomic approach to identify anti-hepatocarcinogenic compounds from plants used traditionally in the treatment of liver diseases. |
2018 |
Fitoterapia |
pmid:29477305
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Incorporation of metabolic enzymes to improve predictivity of reporter gene assay results for estrogenic and anti-androgenic activity. |
2018 |
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Protective effects of apigenin against 3-MCPD-induced renal injury in rat. |
2018 |
Chem. Biol. Interact. |
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Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects. |
2018 |
J. Exp. Clin. Cancer Res. |
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Long-Term Effect on Bioactive Components and Antioxidant Activity of Thermal and High-Pressure Pasteurization of Orange Juice. |
2018 |
Molecules |
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Effect of apigenin on apoptosis induced by renal ischemia/reperfusion injury in vivo and in vitro. |
2018 |
Ren Fail |
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Synthesis of scutellarein derivatives with antiproliferative activity and selectivity through the intrinsic pathway. |
2018 |
Eur J Med Chem |
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Chromatographic fingerprint analysis, antioxidant properties, and inhibition of cholinergic enzymes (acetylcholinesterase and butyrylcholinesterase) of phenolic extracts from Irvingia gabonensis (Aubry-Lecomte ex O'Rorke) Baill bark. |
2018 |
J Basic Clin Physiol Pharmacol |
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Preventive effect of apigenin against isoproterenol-induced apoptosis in cardiomyoblasts. |
2018 |
J. Biochem. Mol. Toxicol. |
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Scutellarin Ameliorates Learning and Memory Deficit via Suppressing [Formula: see text]-Amyloid Formation and Microglial Activation in Rats with Chronic Cerebral Hypoperfusion. |
2018 |
Am. J. Chin. Med. |
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Spirodela polyrhiza and its Chemical Constituent Vitexin Exert Anti-Allergic Effect via ORAI1 Channel Inhibition. |
2018 |
Am. J. Chin. Med. |
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Characterization of the In Vivo and In Vitro Metabolites of Linarin in Rat Biosamples and Intestinal Flora Using Ultra-High Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Tandem Mass Spectrometry. |
2018 |
Molecules |
pmid:30149616
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Apigenin promotes TRAIL-mediated apoptosis regardless of ROS generation. |
2018 |
Food Chem. Toxicol. |
pmid:29247770
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Apigenin and apigeninidin isolates from the Sorghum bicolor leaf targets inflammation via cyclo-oxygenase-2 and prostaglandin-E blockade. |
2018 |
Int J Rheum Dis |
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Downregulating CD26/DPPIV by apigenin modulates the interplay between Akt and Snail/Slug signaling to restrain metastasis of lung cancer with multiple EGFR statuses. |
2018 |
J. Exp. Clin. Cancer Res. |
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Apigenin Inhibits UVB-Induced Skin Carcinogenesis: The Role of Thrombospondin-1 as an Anti-Inflammatory Factor. |
2018 |
Neoplasia |
pmid:30118999
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