| MeSH term | MeSH ID | Detail |
|---|---|---|
| Encephalitis | D004660 | 15 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Neoplasm Invasiveness | D009361 | 23 associated lipids |
| Memory Disorders | D008569 | 33 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Ventricular Remodeling | D020257 | 28 associated lipids |
| Muscular Dystrophy, Duchenne | D020388 | 11 associated lipids |
| Cocaine-Related Disorders | D019970 | 3 associated lipids |
| Premature Birth | D047928 | 6 associated lipids |
| Hypoxia-Ischemia, Brain | D020925 | 22 associated lipids |
| Genomic Instability | D042822 | 7 associated lipids |
| Prostatic Neoplasms, Castration-Resistant | D064129 | 3 associated lipids |
| Chromosomal Instability | D043171 | 5 associated lipids |
| Lymphoma, Primary Effusion | D054685 | 2 associated lipids |
apigenin
apigenin is a lipid of Polyketides (PK) class. Apigenin is associated with abnormalities such as Morphologically altered structure, Chimera disorder, Hypertensive disease, infection induced and Infection. The involved functions are known as inhibitors, Gene Expression, Process, Metabolic Inhibition and Cell Death. Apigenin often locates in Vacuole, Cytoplasmic matrix, Cytoplasm, Tissue membrane and Membrane. The associated genes with apigenin are MSMP gene, BCL2 gene, PTGS2 gene, Chromatin and SLC33A1 gene. The related lipids are Lipopolysaccharides, Steroids, 1-Butanol, agosterol A and Butyrates. The related experimental models are Mouse Model, Tissue Model, Knock-out, Xenograft Model and Disease model.
Cross Reference
Introduction
To understand associated biological information of apigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with apigenin?
apigenin is suspected in Pneumonia, Morphologically altered structure, Hypertensive disease, Dermatitis, Infection, Senile Plaques and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with apigenin
PubChem Associated disorders and diseases
What pathways are associated with apigenin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with apigenin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with apigenin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with apigenin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with apigenin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with apigenin?
Mouse Model
Mouse Model are used in the study 'Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation.' (Nicholas C et al., 2007), Mouse Model are used in the study 'Plant flavonoid apigenin inactivates Akt to trigger apoptosis in human prostate cancer: an in vitro and in vivo study.' (Kaur P et al., 2008) and Mouse Model are used in the study 'Apigenin alleviates the symptoms of Staphylococcus aureus pneumonia by inhibiting the production of alpha-hemolysin.' (Dong J et al., 2013).
Xenograft Model
Xenograft Model are used in the study 'Induction of caspase-dependent, p53-mediated apoptosis by apigenin in human neuroblastoma.' (Torkin R et al., 2005).
Tissue Model
Tissue Model are used in the study 'Dietary phytophenols curcumin, naringenin and apigenin reduce infection-induced inflammatory and contractile pathways in human placenta, foetal membranes and myometrium.' (Lim R et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with apigenin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Myhrstad MC et al. | Flavonoids increase the intracellular glutathione level by transactivation of the gamma-glutamylcysteine synthetase catalytical subunit promoter. | 2002 | Free Radic. Biol. Med. | pmid:11864778 |
| Nazaruk J and Gudej J | Qualitative and quantitative chromatographic investigation of flavonoids in Bellis perennis L. | 2001 Sep-Oct | Acta Pol Pharm | pmid:11876448 |
| Afaq F et al. | Botanical antioxidants for chemoprevention of photocarcinogenesis. | 2002 | Front. Biosci. | pmid:11897547 |
| Liu Y and Hu M | Absorption and metabolism of flavonoids in the caco-2 cell culture model and a perused rat intestinal model. | 2002 | Drug Metab. Dispos. | pmid:11901089 |
| Sun J et al. | [Investigation on method speliality in identifying Fructus Crataegi with vitexin rhamnoside]. | 2001 | Zhong Yao Cai | pmid:11917841 |
| Zhang YH et al. | Endothelium-dependent vasorelaxant and antiproliferative effects of apigenin. | 2000 | Gen. Pharmacol. | pmid:11922965 |
| Salah AM et al. | Estrogenic and cholinergic properties of the methanol extract of Ruellia praetermissa Sceinf. ex. Lindau (Acanthaceae) in female rats. | 2002 | Phytomedicine | pmid:11924764 |
| Kim MK et al. | Relationships of urinary phyto-oestrogen excretion to BMD in postmenopausal women. | 2002 | Clin. Endocrinol. (Oxf) | pmid:11940043 |
| Vanhoenacker G et al. | Chemotaxonomic features associated with flavonoids of cannabinoid-free cannabis (Cannabis sativa subsp. sativa L.) in relation to hops (Humulus lupulus L.). | 2002 | Nat Prod Lett | pmid:11942684 |
| Ohno S et al. | Effects of flavonoid phytochemicals on cortisol production and on activities of steroidogenic enzymes in human adrenocortical H295R cells. | 2002 | J. Steroid Biochem. Mol. Biol. | pmid:11948020 |
| Walle UK and Walle T | Induction of human UDP-glucuronosyltransferase UGT1A1 by flavonoids-structural requirements. | 2002 | Drug Metab. Dispos. | pmid:11950788 |
| Breinholt VM et al. | In vitro investigation of cytochrome P450-mediated metabolism of dietary flavonoids. | 2002 | Food Chem. Toxicol. | pmid:11955666 |
| Lin CM et al. | Prevention of cellular ROS damage by isovitexin and related flavonoids. | 2002 | Planta Med. | pmid:11988866 |
| Kim HR et al. | Flavonoids differentially inhibit guinea pig epidermal cytosolic phospholipase A2. | 2001 Nov-Dec | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11993721 |
| Rager I et al. | Rapid quantification of constituents in St. John's wort extracts by NIR spectroscopy. | 2002 | J Pharm Biomed Anal | pmid:12008122 |
| Zhu CC et al. | Dimerization and phosphorylation of thyrotropin-releasing hormone receptors are modulated by agonist stimulation. | 2002 | J. Biol. Chem. | pmid:12023974 |
| Usia T et al. | Constituents of Chinese propolis and their antiproliferative activities. | 2002 | J. Nat. Prod. | pmid:12027739 |
| Gupta S et al. | Involvement of nuclear factor-kappa B, Bax and Bcl-2 in induction of cell cycle arrest and apoptosis by apigenin in human prostate carcinoma cells. | 2002 | Oncogene | pmid:12032841 |
| Bito T et al. | Flavonoids differentially regulate IFN gamma-induced ICAM-1 expression in human keratinocytes: molecular mechanisms of action. | 2002 | FEBS Lett. | pmid:12044887 |
| Zou L et al. | Effects of intrinsic fluorescence and quenching on fluorescence-based screening of natural products. | 2002 | Phytomedicine | pmid:12046870 |