apigenin

apigenin is a lipid of Polyketides (PK) class. Apigenin is associated with abnormalities such as Morphologically altered structure, Chimera disorder, Hypertensive disease, infection induced and Infection. The involved functions are known as inhibitors, Gene Expression, Process, Metabolic Inhibition and Cell Death. Apigenin often locates in Vacuole, Cytoplasmic matrix, Cytoplasm, Tissue membrane and Membrane. The associated genes with apigenin are MSMP gene, BCL2 gene, PTGS2 gene, Chromatin and SLC33A1 gene. The related lipids are Lipopolysaccharides, Steroids, 1-Butanol, agosterol A and Butyrates. The related experimental models are Mouse Model, Tissue Model, Knock-out, Xenograft Model and Disease model.

Cross Reference

Introduction

To understand associated biological information of apigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with apigenin?

apigenin is suspected in Pneumonia, Morphologically altered structure, Hypertensive disease, Dermatitis, Infection, Senile Plaques and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with apigenin

MeSH term MeSH ID Detail
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thrombosis D013927 49 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Alzheimer Disease D000544 76 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Leukemia D007938 74 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Brain Infarction D020520 17 associated lipids
Per page 10 20 50 100 | Total 64

PubChem Associated disorders and diseases

What pathways are associated with apigenin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with apigenin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with apigenin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with apigenin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with apigenin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with apigenin?

Mouse Model

Mouse Model are used in the study 'Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation.' (Nicholas C et al., 2007), Mouse Model are used in the study 'Plant flavonoid apigenin inactivates Akt to trigger apoptosis in human prostate cancer: an in vitro and in vivo study.' (Kaur P et al., 2008) and Mouse Model are used in the study 'Apigenin alleviates the symptoms of Staphylococcus aureus pneumonia by inhibiting the production of alpha-hemolysin.' (Dong J et al., 2013).

Xenograft Model

Xenograft Model are used in the study 'Induction of caspase-dependent, p53-mediated apoptosis by apigenin in human neuroblastoma.' (Torkin R et al., 2005).

Tissue Model

Tissue Model are used in the study 'Dietary phytophenols curcumin, naringenin and apigenin reduce infection-induced inflammatory and contractile pathways in human placenta, foetal membranes and myometrium.' (Lim R et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with apigenin

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Per page 10 20 50 100 | Total 2777
Authors Title Published Journal PubMed Link
Dai C et al. [Studies on chemical constituents from moss Rhodobryum roseum II]. 2006 Zhongguo Zhong Yao Za Zhi pmid:17048608
Hua Y and Wang HQ [Studies on the flavonoids from whole herbs of Seriphidium terrae-albae]. 2006 Zhongguo Zhong Yao Za Zhi pmid:17048665
Han SL et al. [Comparison of antioxidant activity between two species of chamomiles produced in Xinjiang by TLC-bioautography]. 2013 Zhongguo Zhong Yao Za Zhi pmid:23672040
Tong C and Wu X [Determination of plasma protein binding rate of vitexin]. 2012 Zhongguo Zhong Yao Za Zhi pmid:23126208
Lei N et al. [Chemical constituents from a Tibetan medicine Arenaria kansuensis I]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17655145
Zhu B et al. [Studies on chemical constituent and quantitative determination of Mallotus apelta]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17655150
Wu X et al. [Studies on flavones in of Lavandula augustifolia]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17639984
Xia CL et al. [Chemical constituents from herbs of Swertia delavayi]. 2008 Zhongguo Zhong Yao Za Zhi pmid:19086635
Zhang S et al. [Studies on chemical constituents of Eriophyton wallichii]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17639985
Wang M et al. [Studies on constituents of Dendrobium gratiosissimum]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17608224
Li YL et al. [Evaluation on preparation process of brevisapin colon-specific tables and its in vitro release]. 2013 Zhongguo Zhong Yao Za Zhi pmid:23717958
Wang L et al. [Studies on chemical constituents from bark of Morus nigra]. 2007 Zhongguo Zhong Yao Za Zhi pmid:18330242
Su EN et al. [Studies on chemical constituents from stems and leaves of Adenanthera pavanina]. 2007 Zhongguo Zhong Yao Za Zhi pmid:18306745
Liu JY et al. [Optimizing extraction process of Scutellaria barbata by golden section method]. 2008 Zhongguo Zhong Yao Za Zhi pmid:18619346
Dawa ZM et al. [Studies on chemical constituents of Saussurea laniceps]. 2008 Zhongguo Zhong Yao Za Zhi pmid:18652351
Yu ZW et al. [Study on chemical constituents from Incarvillea arguta and their accelerating PC-12 cell differentiation]. 2005 Zhongguo Zhong Yao Za Zhi pmid:16323541
Shi S et al. [Evaluation of brain-targeted trendence of scutellarin nasal administration]. 2010 Zhongguo Zhong Yao Za Zhi pmid:21141499
Zhu LW et al. [Pharmacokinetics of scutellarin and its derivant scutellarin ethyl ester in rats]. 2013 Zhongguo Zhong Yao Za Zhi pmid:24422411
Huo CH et al. [Studies on chemical constituents in herbs of Acanthus ilicifolius]. 2005 Zhongguo Zhong Yao Za Zhi pmid:16075716
Li K et al. [Study on fragmentation of vitexin and isorhamnetin-3-O-beta-D-rutinoside using electrospray quadrupole time of flight mass spectrometry]. 2011 Zhongguo Zhong Yao Za Zhi pmid:21506419
Shi T et al. [Effect of apigenin on protein expressions of PPARs in liver tissues of rats with nonalcoholic steatohepatitis]. 2015 Zhonghua Gan Zang Bing Za Zhi pmid:25880979
Shi XR et al. [Apigenin affects semen parameters in male mice]. 2010 Zhonghua Nan Ke Xue pmid:21171258
Yao HM et al. [Effects of apigenin on lipopolysaccharide induced proliferation of rat aortic vascular smooth muscle cells]. 2017 Zhonghua Xin Xue Guan Bing Za Zhi pmid:28545285
Xing Y et al. [Bystander effect mediated by herpes simplex virus-thymidine kinase/ganciclovir approach on prostatic cancer cells and its regulation]. 2002 Zhonghua Yi Xue Za Zhi pmid:12509912
Wang LY et al. [Apigenin regulates lipopolysaccharides-induced activation of inflammasome]. 2011 Zhonghua Yi Xue Za Zhi pmid:22321793
Jin XY and Ren CS [Effect and mechanism of apigenin on VEGF expression in human breast cancer cells]. 2007 Zhonghua Zhong Liu Za Zhi pmid:18069627
Tatemoto H et al. Inhibition of boar sperm hyaluronidase activity by tannic acid reduces polyspermy during in vitro fertilization of porcine oocytes. 2006 Zygote pmid:17266786