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Role of HER2/HER3 co-receptor in breast carcinogenesis. |
2005 |
Future Oncol |
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Flavonoid quercetin, but not apigenin or luteolin, induced apoptosis in human myeloid leukemia cells and their resistant variants. |
2005 |
Neoplasma |
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Phytotoxic activity of bibenzyl derivatives from the orchid Epidendrum rigidum. |
2005 |
J. Agric. Food Chem. |
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Characterization of flavonoids by aluminum complexation and collisionally activated dissociation. |
2005 |
J Mass Spectrom |
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Apigenin decreases hemin-mediated heme oxygenase-1 induction. |
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Free Radic. Biol. Med. |
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Antiviral activities of extracts and selected pure constituents of Ocimum basilicum. |
2005 |
Clin. Exp. Pharmacol. Physiol. |
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Identification and mass spectrometric characterization of glycosylated flavonoids in Triticum durum plants by high-performance liquid chromatography with tandem mass spectrometry. |
2005 |
Rapid Commun. Mass Spectrom. |
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A possible quantitative method to improve the sensitivity of scutellarin in human plasma. |
2005 |
Ann Chim |
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Isovitexin suppresses lipopolysaccharide-mediated inducible nitric oxide synthase through inhibition of NF-kappa B in mouse macrophages. |
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Planta Med. |
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[Effect of caffeic acid, seopoletin and scutellarin on rat retinal neurons in vitro]. |
2005 |
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Flavonoids and tyrosine nitration: structure-activity relationship correlation with enthalpy of formation. |
2005 |
Toxicol In Vitro |
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Structural and mechanistic studies on anthocyanidin synthase catalysed oxidation of flavanone substrates: the effect of C-2 stereochemistry on product selectivity and mechanism. |
2005 |
Org. Biomol. Chem. |
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Two acylated flavonoid glycosides from Stachys bombycina, and their free radical scavenging activity. |
2005 |
Pharmazie |
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[Study on chemical constituents from Incarvillea arguta and their accelerating PC-12 cell differentiation]. |
2005 |
Zhongguo Zhong Yao Za Zhi |
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B23 is a downstream target of polyamine-modulated CK2. |
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Mol. Cell. Biochem. |
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Inducible IkappaB kinase/IkappaB kinase epsilon expression is induced by CK2 and promotes aberrant nuclear factor-kappaB activation in breast cancer cells. |
2005 |
Cancer Res. |
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Differentiation of androgen-independent prostate cancer PC-3 cells is associated with increased nuclear factor-kappaB activity. |
2005 |
Cancer Res. |
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Nazaruk J and Jakoniuk P |
Flavonoid composition and antimicrobial activity of Cirsium rivulare (Jacq.) All. flowers. |
2005 |
J Ethnopharmacol |
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Dose-response effects of phytoestrogens on the activity and expression of 3beta-hydroxysteroid dehydrogenase and aromatase in human granulosa-luteal cells. |
2005 |
J. Steroid Biochem. Mol. Biol. |
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Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2. |
2005 |
Biochem. Pharmacol. |
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Lamien CE et al. |
Inhibition of fowlpox virus by an aqueous acetone extract from galls of Guiera senegalensis J. F. Gmel (Combretaceae). |
2005 |
J Ethnopharmacol |
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Quantitative determination of the group of flavonoids and saponins from the extracts of the seeds of Glinus lotoides and tablet formulation thereof by high-performance liquid chromatography. |
2005 |
J Chromatogr A |
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Multivesicular liposome formulation for the sustained delivery of breviscapine. |
2005 |
Int J Pharm |
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The anti-HIV-1 effect of scutellarin. |
2005 |
Biochem. Biophys. Res. Commun. |
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Inhibitory effects of apigenin on the growth of gastric carcinoma SGC-7901 cells. |
2005 |
World J. Gastroenterol. |
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2005 |
J. Nat. Prod. |
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Dietary flavonoids as intracellular substrates for an erythrocyte trans-plasma membrane oxidoreductase activity. |
2005 |
Br. J. Nutr. |
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[Studies on chemical constituents from the flowers of Carthamus tinctorius L]. |
2005 |
Zhong Yao Cai |
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Anti-HIV activity of dibenzylbutyrolactone-type lignans from Phenax species endemic in Costa Rica. |
2005 |
J. Pharm. Pharmacol. |
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Determination of active components in rosemary by capillary electrophoresis with electrochemical detection. |
2005 |
J Pharm Biomed Anal |
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Mechanisms of apigenin-7-glucoside as a hepatoprotective agent. |
2005 |
Biomed. Environ. Sci. |
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Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis. |
2005 |
Proc. Natl. Acad. Sci. U.S.A. |
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Study on the role of hepatic first-pass elimination in the low oral bioavailability of scutellarin in rats. |
2005 |
Pharmazie |
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Inhibitory effects of a rice hull constituent on tumor necrosis factor alpha, prostaglandin E2, and cyclooxygenase-2 production in lipopolysaccharide-activated mouse macrophages. |
2005 |
Ann. N. Y. Acad. Sci. |
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The effects of apigenin-7-O-beta-D-glucuronopyranoside on reflux oesophagitis and gastritis in rats. |
2005 |
Auton Autacoid Pharmacol |
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Biotransformation of chrysin and apigenin by Cunninghamella elegans. |
2005 |
Chem. Pharm. Bull. |
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Analysis of flavonoids in leaves of Adinandra nitida by capillary electrochromatography on monolithic columns with stepwise gradient elution. |
2005 |
J Sep Sci |
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[Studies on chemical constituents in herb of Chondrilla piptocoma]. |
2005 |
Zhongguo Zhong Yao Za Zhi |
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Precision improvement for the analysis of flavonoids in selected Thai plants by capillary zone electrophoresis. |
2005 |
Electrophoresis |
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Antiradical activity of hydrolyzed and non-hydrolyzed extracts from Helichrysi inflorescentia and its phenolic contents. |
2004 May-Jun |
Z. Naturforsch., C, J. Biosci. |
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Polyphenolic compounds from Platycodon grandiflorum A. DC. |
2004 May-Jun |
Acta Pol Pharm |
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A HPTLC densitometric determination of flavonoids from Passiflora alata, P. edulis, P. incarnata and P. caerulea and comparison with HPLC method. |
2004 Jul-Aug |
Phytochem Anal |
pmid:15311844
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Kaiser CS et al. |
Supercritical carbon dioxide extraction of chamomile flowers: extraction efficiency, stability, and in-line inclusion of chamomile-carbon dioxide extract in beta-cyclodextrin. |
2004 Jul-Aug |
Phytochem Anal |
pmid:15311845
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Fonseca FN and Tavares MF |
Validation of a capillary electrophoresis method for the quantitative determination of free and total apigenin in extracts of Chamomilla recutita. |
2004 Jan-Feb |
Phytochem Anal |
pmid:14979529
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Garnovskaya MN et al. |
Mitogen-induced rapid phosphorylation of serine 795 of the retinoblastoma gene product in vascular smooth muscle cells involves ERK activation. |
2004 |
J. Biol. Chem. |
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Pulmonary surfactant protein A augments the phagocytosis of Streptococcus pneumoniae by alveolar macrophages through a casein kinase 2-dependent increase of cell surface localization of scavenger receptor A. |
2004 |
J. Biol. Chem. |
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Tumour necrosis factor and PI3-kinase control oestrogen receptor alpha protein level and its transrepression function. |
2004 |
Br. J. Cancer |
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A hydroxyl group of flavonoids affects oral anti-inflammatory activity and inhibition of systemic tumor necrosis factor-alpha production. |
2004 |
Biosci. Biotechnol. Biochem. |
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Vascular and anti-oxidant actions of flavonols and flavones. |
2004 |
Clin. Exp. Pharmacol. Physiol. |
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Analysis of minor components in olive oil. |
2004 |
J. Biochem. Biophys. Methods |
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Flavonoids from shoots, roots and roots exudates of Brassica alba. |
2004 |
Phytochemistry |
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Hepatoprotective and free radical scavenging activities of phenolic petrosins and flavonoids isolated from Equisetum arvense. |
2004 |
J Ethnopharmacol |
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Study of flavonoids of Sechium edule (Jacq) Swartz (Cucurbitaceae) different edible organs by liquid chromatography photodiode array mass spectrometry. |
2004 |
J. Agric. Food Chem. |
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Cell signaling pathways altered by natural chemopreventive agents. |
2004 |
Mutat. Res. |
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Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels. |
2004 |
Naunyn Schmiedebergs Arch. Pharmacol. |
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Antimicrobial activity and cytotoxicity of Cirsium tenoreanum. |
2004 |
Fitoterapia |
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Anti-apoptotic action of (2S,3S,4R)-N"-cyano-N-(6-amino-3,4-dihydro-3-hydroxy-2-methyl-2-dimethoxymethyl-2H-benzopyran-4-yl)-N'-benzylguanidine (KR-31378) by suppression of the phosphatase and tensin homolog deleted from chromosome 10 phosphorylation and increased phosphorylation of casein kinase2/Akt/ cyclic AMP response element binding protein via maxi-K channel opening in neuronal cells. |
2004 |
Eur. J. Pharmacol. |
pmid:15336944
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Gutierrez-Lugo MT et al. |
Lipoxygenase inhibition by anadanthoflavone, a new flavonoid from the aerial parts of Anadenanthera colubrina. |
2004 |
Planta Med. |
pmid:15114507
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Acetylated flavonoid glycosides potentiating NGF action from Scoparia dulcis. |
2004 |
J. Nat. Prod. |
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Trypanocidal and antimicrobial activities of Moquinia kingii. |
2004 |
Phytomedicine |
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Cytotoxic activities of flavonoids from two Scutellaria plants in Chinese medicine. |
2004 |
J Ethnopharmacol |
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Monitoring the antioxidant activity of extracts originated from various Serratula species and isolation of flavonoids from Serratula coronata. |
2004 |
Fitoterapia |
pmid:15030920
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Prediction of ligand binding affinity and orientation of xenoestrogens to the estrogen receptor by molecular dynamics simulations and the linear interaction energy method. |
2004 |
J. Med. Chem. |
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Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica. |
2004 |
Bioorg. Med. Chem. Lett. |
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Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake. |
2004 |
J. Biol. Chem. |
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Isolation, identification and stability of acylated derivatives of apigenin 7-O-glucoside from chamomile (Chamomilla recutita [L.] Rauschert). |
2004 |
Phytochemistry |
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Unbalanced activation of ERK1/2 and MEK1/2 in apigenin-induced HeLa cell death. |
2004 |
Exp. Cell Res. |
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Inhibition of mouth skeletal muscle relaxation by flavonoids of Cistus ladanifer L.: a plant defense mechanism against herbivores. |
2004 |
J. Chem. Ecol. |
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The flavones luteolin and apigenin inhibit in vitro antigen-specific proliferation and interferon-gamma production by murine and human autoimmune T cells. |
2004 |
Biochem. Pharmacol. |
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Stroheker T et al. |
Steroid activities comparison of natural and food wrap compounds in human breast cancer cell lines. |
2004 |
Food Chem. Toxicol. |
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Muanprasat C et al. |
Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy. |
2004 |
J. Gen. Physiol. |
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Individual and interactive effects of apigenin analogs on G2/M cell-cycle arrest in human colon carcinoma cell lines. |
2004 |
Nutr Cancer |
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Oncogenic Ras promotes butyrate-induced apoptosis through inhibition of gelsolin expression. |
2004 |
J. Biol. Chem. |
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The flavone hispidulin, a benzodiazepine receptor ligand with positive allosteric properties, traverses the blood-brain barrier and exhibits anticonvulsive effects. |
2004 |
Br. J. Pharmacol. |
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Kang SS et al. |
Neuroprotective effects of flavones on hydrogen peroxide-induced apoptosis in SH-SY5Y neuroblostoma cells. |
2004 |
Bioorg. Med. Chem. Lett. |
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Dietary compounds prevent oxidative damage and nitric oxide production by cells involved in demyelinating disease. |
2004 |
Biochem. Pharmacol. |
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Li HH et al. |
Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression. |
2004 |
Mol. Cell |
pmid:15053879
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Scutellarin attenuates oxidative glutamate toxicity in PC12 cells. |
2004 |
Planta Med. |
pmid:15124087
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Shukla S and Gupta S |
Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes. |
2004 |
Clin. Cancer Res. |
pmid:15131058
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Eltayeb AA et al. |
Antagonistic effect of scutellarin on the toxicity of selenium in rat livers. |
2004 |
Biol Trace Elem Res |
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SvehlÃková V et al. |
Interactions between sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in CaCo-2 cells. |
2004 |
Carcinogenesis |
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Phytoestrogens in common herbs regulate prostate cancer cell growth in vitro. |
2004 |
Nutr Cancer |
pmid:15489213
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Shukla S and Gupta S |
Molecular mechanisms for apigenin-induced cell-cycle arrest and apoptosis of hormone refractory human prostate carcinoma DU145 cells. |
2004 |
Mol. Carcinog. |
pmid:14750216
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Metabolism of apigenin by rat liver phase I and phase ii enzymes and by isolated perfused rat liver. |
2004 |
Drug Metab. Dispos. |
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Cross talk of cAMP and flavone in regulation of cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel and Na+/K+/2Cl- cotransporter in renal epithelial A6 cells. |
2004 |
Biochem. Pharmacol. |
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Apigenin induces apoptosis through proteasomal degradation of HER2/neu in HER2/neu-overexpressing breast cancer cells via the phosphatidylinositol 3-kinase/Akt-dependent pathway. |
2004 |
J. Biol. Chem. |
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Differential effects of natural flavonoids on growth and iodide content in a human Na*/I- symporter-transfected follicular thyroid carcinoma cell line. |
2004 |
Eur. J. Endocrinol. |
pmid:15080787
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Protection against hydrogen peroxide-induced cytotoxicity in PC12 cells by scutellarin. |
2004 |
Life Sci. |
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Inhibitory effects of flavonoids on phosphodiesterase isozymes from guinea pig and their structure-activity relationships. |
2004 |
Biochem. Pharmacol. |
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Inhibition of the rat breast cytosolic bioactivation of ethanol to acetaldehyde by some plant polyphenols and folic acid. |
2004 |
Nutr Cancer |
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Structural aspects of flavonoids as trypsin inhibitors. |
2004 |
Eur J Med Chem |
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Active components from Artemisia iwayomogi displaying ONOO(-) scavenging activity. |
2004 |
Phytother Res |
pmid:14750192
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Matsufuji H and Shibamoto T |
Inhibition of malonaldehyde formation in oxidized calf thymus DNA with synthetic and natural antioxidants. |
2004 |
J. Agric. Food Chem. |
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Liu Z et al. |
[Determination of orientin and vitexin in Trollius chinesis preparation by HPLC]. |
2004 |
Zhongguo Zhong Yao Za Zhi |
pmid:15656135
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[Study on the chemical constituents from Picria fel-tarrae]. |
2004 |
Zhongguo Zhong Yao Za Zhi |
pmid:15719682
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Combined effects of elevated CO2 and herbivore damage on alfalfa and cotton. |
2004 |
J. Chem. Ecol. |
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[Studies on chemical constituents from herb of Dracocephalum moldavica]. |
2004 |
Zhongguo Zhong Yao Za Zhi |
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Campbell EL et al. |
The dietary flavonoids apigenin and (-)-epigallocatechin gallate enhance the positive modulation by diazepam of the activation by GABA of recombinant GABA(A) receptors. |
2004 |
Biochem. Pharmacol. |
pmid:15451406
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Wang SP and Huang KJ |
Determination of flavonoids by high-performance liquid chromatography and capillary electrophoresis. |
2004 |
J Chromatogr A |
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Evaluation of the first-pass glucuronidation of selected flavones in gut by Caco-2 monolayer model. |
2004 |
J Pharm Pharm Sci |
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