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Preparation, characterization and antitumor activity evaluation of apigenin nanoparticles by the liquid antisolvent precipitation technique. |
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Protective effects of apigenin against acrylonitrile-induced subchronic sperm injury in rats. |
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Complementary cereals and legumes for health: Synergistic interaction of sorghum flavones and cowpea flavonols against LPS-induced inflammation in colonic myofibroblasts. |
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Mol Nutr Food Res |
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Characterization of phenolic compounds in green and red oak-leaf lettuce cultivars by UHPLC-DAD-ESI-QToF/MS using MS scan mode. |
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J Mass Spectrom |
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Oxid Med Cell Longev |
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Molecules |
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Apigenin attenuates isoflurane-induced cognitive dysfunction via epigenetic regulation and neuroinflammation in aged rats. |
2017 |
Arch Gerontol Geriatr |
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Protective role of apigenin on rotenone induced rat model of Parkinson's disease: Suppression of neuroinflammation and oxidative stress mediated apoptosis. |
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Apigenin attenuates hippocampal oxidative events, inflammation and pathological alterations in rats fed high fat, fructose diet. |
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Biomed. Pharmacother. |
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Apigenin attenuates streptozotocin-induced pancreatic β cell damage by its protective effects on cellular antioxidant defense. |
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Formulation and characterization of an apigenin-phospholipid phytosome (APLC) for improved solubility, in vivo bioavailability, and antioxidant potential. |
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Eur J Pharm Sci |
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Comparative study of the binding of 3 flavonoids to the fat mass and obesity-associated protein by spectroscopy and molecular modeling. |
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Simultaneous quantification and identification of flavonoids, lignans, coumarin and amides in leaves of Zanthoxylum armatum using UPLC-DAD-ESI-QTOF-MS/MS. |
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J Pharm Biomed Anal |
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Preparation of Vitexin Nanoparticles by Combining the Antisolvent Precipitation and High Pressure Homogenization Approaches Followed by Lyophilization for Dissolution Rate Enhancement. |
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Molecules |
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Identification of Major Flavone C-Glycosides and Their Optimized Extraction from Cymbidium kanran Using Deep Eutectic Solvents. |
2017 |
Molecules |
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Apigenin, a novel candidate involving herb-drug interaction (HDI), interacts with organic anion transporter 1 (OAT1). |
2017 |
Pharmacol Rep |
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Scutellarin Inhibits Proliferation, Invasion, and Tumorigenicity in Human Breast Cancer Cells by Regulating HIPPO-YAP Signaling Pathway. |
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Study of Sedative Tea Phytocomplex within the Framework of Studies Aimed at Creation of a Rectal Dosage Form with Antihistaminic Effect. |
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Swertisin rich fraction from Enicostema littorale ameliorates hyperglycemia and hyperlipidemia in high-fat fed diet and low dose streptozotacin induced type 2 diabetes mellitus in rats. |
2017 |
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Apigenin Ameliorates the Obesity-Induced Skeletal Muscle Atrophy by Attenuating Mitochondrial Dysfunction in the Muscle of Obese Mice. |
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Mol Nutr Food Res |
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2017 |
Carbohydr Polym |
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Apigenin exhibits protective effects in a mouse model of d-galactose-induced aging via activating the Nrf2 pathway. |
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Apigenin ameliorates streptozotocin-induced diabetic nephropathy in rats via MAPK-NF-κB-TNF-α and TGF-β1-MAPK-fibronectin pathways. |
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Genotoxicity and Antigenotoxicity Assessments of the Flavonoid Vitexin by the Drosophila melanogaster Somatic Mutation and Recombination Test. |
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J Med Food |
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C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review. |
2017 |
Phytother Res |
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Scutellarin derivatives as apoptosis inducers: Design, synthesis and biological evaluation. |
2017 |
Eur J Med Chem |
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Comparison of phenolic acids and flavonoids contents in various cultivars and parts of common lavender (Lavandula angustifolia) derived from Poland. |
2017 |
Nat. Prod. Res. |
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Natural antioxidant flavonoids in formalin-induced mice paw inflammation; inhibition of mitochondrial sorbitol dehydrogenase activity. |
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Apigenin, a modulator of PPARγ, attenuates HFD-induced NAFLD by regulating hepatocyte lipid metabolism and oxidative stress via Nrf2 activation. |
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Effects of Apigenin on Experimental Ischemia/Reperfusion Injury in the Rat Ovary. |
2017 |
Balkan Med J |
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An efficient approach for the extraction of orientin and vitexin from Trollius chinensis flowers using ultrasonic circulating technique. |
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Ultrason Sonochem |
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2017 |
Sci Rep |
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Study on the Pulmonary Delivery System of Apigenin-Loaded Albumin Nanocarriers with Antioxidant Activity. |
2017 |
J Aerosol Med Pulm Drug Deliv |
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Antioxidative and Protective Actions of Apigenin in a Paracetamol-Induced Hepatotoxicity Rat Model. |
2017 |
Eur J Drug Metab Pharmacokinet |
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Development and optimization of apigenin-loaded transfersomal system for skin cancer delivery: in vitro evaluation. |
2017 |
Artif Cells Nanomed Biotechnol |
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Scutellarin suppresses growth and causes apoptosis of human colorectal cancer cells by regulating the p53 pathway. |
2017 |
Mol Med Rep |
pmid:28035355
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Enhanced chemotherapeutic efficacy of apigenin liposomes in colorectal cancer based on flavone-membrane interactions. |
2017 |
J Colloid Interface Sci |
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Scutellarin suppresses migration and invasion of human hepatocellular carcinoma by inhibiting the STAT3/Girdin/Akt activity. |
2017 |
Biochem. Biophys. Res. Commun. |
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Pharmacokinetic Study of Swertisin by HPLC-MS/MS After Intravenous Administration in Rats. |
2017 |
J Chromatogr Sci |
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Apigenin induces both intrinsic and extrinsic pathways of apoptosis in human colon carcinoma HCT-116 cells. |
2017 |
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Covalent Immobilization of Human Placental 17β-Hydroxysteroid Dehydrogenase Type 1 onto Glutaraldehyde Activated Silica Coupled with LC-TOF/MS for Anti-Cancer Drug Screening Applications. |
2017 |
Appl. Biochem. Biotechnol. |
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Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPARα-mediated lipogenic gene expression. |
2017 |
Chem. Biol. Interact. |
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Apigenin potentiates the antitumor activity of 5-FU on solid Ehrlich carcinoma: Crosstalk between apoptotic and JNK-mediated autophagic cell death platforms. |
2017 |
Toxicol. Appl. Pharmacol. |
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Cholinesterase inhibitory, anti-amyloidogenic and neuroprotective effect of the medicinal plant Grewia tiliaefolia - An in vitro and in silico study. |
2017 |
Pharm Biol |
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Plant-derived flavone Apigenin: The small-molecule with promising activity against therapeutically resistant prostate cancer. |
2017 |
Biomed. Pharmacother. |
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Inhibition of MDA-MB-231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation-mediated p21 expression. |
2017 |
Environ. Toxicol. |
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Dietary flavones counteract phorbol 12-myristate 13-acetate-induced SREBP-2 processing in hepatic cells. |
2017 |
Mol. Cell. Biochem. |
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Swertisin ameliorates pre-pulse inhibition deficits and cognitive impairment induced by MK-801 in mice. |
2017 |
J. Psychopharmacol. (Oxford) |
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Quality assessment of marketed chamomile tea products by a validated HPTLC method combined with multivariate analysis. |
2017 |
J Pharm Biomed Anal |
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Effect of the storage time and temperature on phenolic compounds of sorghum grain and flour. |
2017 |
Food Chem |
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Controlled Release Oral Delivery of Apigenin Containing Pellets with Antioxidant Activity. |
2017 |
Curr Drug Deliv |
pmid:27264725
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Apigenin reduce lipoteichoic acid-induced inflammatory response in rat cardiomyoblast cells. |
2017 |
Arch. Pharm. Res. |
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Correlation of binding efficacies of DNA to flavonoids and their induced cellular damage. |
2017 |
J. Photochem. Photobiol. B, Biol. |
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Novel cationic lipid nanoparticles as an ophthalmic delivery system for multicomponent drugs: development, characterization, in vitro permeation, in vivo pharmacokinetic, and molecular dynamics studies. |
2017 |
Int J Nanomedicine |
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Protective effects of apigenin and myricetin against cisplatin-induced nephrotoxicity in mice. |
2017 |
Pharm Biol |
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Phytochemical components and biological activities of Silene arenarioides Desf. |
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Nat. Prod. Res. |
pmid:28278644
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Phenolic compounds apigenin, hesperidin and kaempferol reduce in vitro lipid accumulation in human adipocytes. |
2017 |
J Transl Med |
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Apigenin inhibits NF-κB and snail signaling, EMT and metastasis in human hepatocellular carcinoma. |
2016 |
Oncotarget |
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Synthetic investigation toward apigenin 5-O-glycoside camellianin B as well as the chemical structure revision. |
2016 |
Org. Biomol. Chem. |
pmid:27145917
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Apigenin-7-O-β-D-glycoside isolation from the highly copper-tolerant plant Elsholtzia splendens. |
2016 |
J Zhejiang Univ Sci B |
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TLC Profiles of Selected Cirsium Species with Chemometrics in Construction of Their Fingerprints. |
2016 |
J Chromatogr Sci |
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Apigenin Ameliorates Dyslipidemia, Hepatic Steatosis and Insulin Resistance by Modulating Metabolic and Transcriptional Profiles in the Liver of High-Fat Diet-Induced Obese Mice. |
2016 |
Nutrients |
pmid:27213439
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Scutellarin as a Potential Therapeutic Agent for Microglia-Mediated Neuroinflammation in Cerebral Ischemia. |
2016 |
Neuromolecular Med. |
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RNA-seq analysis of the Rhizobium tropici CIAT 899 transcriptome shows similarities in the activation patterns of symbiotic genes in the presence of apigenin and salt. |
2016 |
BMC Genomics |
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Dietary Apigenin Exerts Immune-Regulatory Activity in Vivo by Reducing NF-κB Activity, Halting Leukocyte Infiltration and Restoring Normal Metabolic Function. |
2016 |
Int J Mol Sci |
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Phenolic Compounds in Extra Virgin Olive Oil Stimulate Human Osteoblastic Cell Proliferation. |
2016 |
PLoS ONE |
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Photochromic Properties of 3-Deoxyanthocyanidin Pigments in Nontoxic Solvents. |
2016 |
J. Food Sci. |
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Attenuation of Pseudomonas aeruginosa biofilm formation by Vitexin: A combinatorial study with azithromycin and gentamicin. |
2016 |
Sci Rep |
pmid:27000525
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Inhibitory Mechanism of Apigenin on α-Glucosidase and Synergy Analysis of Flavonoids. |
2016 |
J. Agric. Food Chem. |
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The flavonoid apigenin reduces prostate cancer CD44(+) stem cell survival and migration through PI3K/Akt/NF-κB signaling. |
2016 |
Life Sci. |
pmid:27569589
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Modification of abomasum contractility by flavonoids present in ruminants diet: in vitro study. |
2016 |
Animal |
pmid:27534882
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Preparation of inclusion complex of apigenin-hydroxypropyl-β-cyclodextrin by using supercritical antisolvent process for dissolution and bioavailability enhancement. |
2016 |
Int J Pharm |
pmid:27515291
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Changes of primary and secondary metabolites in barley plants exposed to CdO nanoparticles. |
2016 |
Environ. Pollut. |
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Constitutive activation of casein kinase 2 in glioblastomas: Absence of class restriction and broad therapeutic potential. |
2016 |
Int. J. Oncol. |
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Antidiabetic and antioxidant effects of saponarin from Gypsophila trichotoma on streptozotocin-induced diabetic normotensive and hypertensive rats. |
2016 |
Phytomedicine |
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Enhancing oral bioavailability using preparations of apigenin-loaded W/O/W emulsions: In vitro and in vivo evaluations. |
2016 |
Food Chem |
pmid:27041302
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Determination of scutellarin in breviscapine preparations using quantitative proton nuclear magnetic resonance spectroscopy. |
2016 |
J Food Drug Anal |
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Apigenin supplementation protects the development of dextran sulfate sodium-induced murine experimental colitis by inhibiting canonical and non-canonical inflammasome signaling pathways. |
2016 |
J. Nutr. Biochem. |
pmid:27012631
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Swertisin, a C-glucosylflavone, ameliorates scopolamine-induced memory impairment in mice with its adenosine A1 receptor antagonistic property. |
2016 |
Behav. Brain Res. |
pmid:26996316
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Simple low-cost miniaturization approach for pharmaceutical nanocrystals production. |
2016 |
Int J Pharm |
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Apigenin Attenuates Inflammation in Experimentally Induced Acute Pancreatitis-Associated Lung Injury. |
2016 |
J Invest Surg |
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Anti-inflammatory effects of vicenin-2 and scolymoside on polyphosphate-mediated vascular inflammatory responses. |
2016 |
Inflamm. Res. |
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Phenolic content, antioxidant activity and effective compounds of kumquat extracted by different solvents. |
2016 |
Food Chem |
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Cytotoxic activity and molecular docking of a novel biflavonoid isolated from Jacaranda acutifolia (Bignoniaceae). |
2016 |
Nat. Prod. Res. |
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Degradable poly(apigenin) polymer inhibits tumor cell adhesion to vascular endothelial cells. |
2016 |
J. Biomed. Mater. Res. Part B Appl. Biomater. |
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Two new flavonoids from Selaginella uncinata. |
2016 |
J Asian Nat Prod Res |
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Anticholinesterase, antioxidant activity and phytochemical investigation into aqueous extracts from five species of Agrimonia genus. |
2016 |
Nat. Prod. Res. |
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Recovery of Chicken Growth Plate by Heat-Shock Protein 90 Inhibitors Epigallocatechin-3-Gallate and Apigenin in Thiram-Induced Tibial Dyschondroplasia. |
2016 |
Avian Dis. |
pmid:27902918
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