apigenin

apigenin is a lipid of Polyketides (PK) class. Apigenin is associated with abnormalities such as Morphologically altered structure, Chimera disorder, Hypertensive disease, infection induced and Infection. The involved functions are known as inhibitors, Gene Expression, Process, Metabolic Inhibition and Cell Death. Apigenin often locates in Vacuole, Cytoplasmic matrix, Cytoplasm, Tissue membrane and Membrane. The associated genes with apigenin are MSMP gene, BCL2 gene, PTGS2 gene, Chromatin and SLC33A1 gene. The related lipids are Lipopolysaccharides, Steroids, 1-Butanol, agosterol A and Butyrates. The related experimental models are Mouse Model, Tissue Model, Knock-out, Xenograft Model and Disease model.

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Introduction

To understand associated biological information of apigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with apigenin?

apigenin is suspected in Pneumonia, Morphologically altered structure, Hypertensive disease, Dermatitis, Infection, Senile Plaques and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with apigenin

MeSH term MeSH ID Detail
Spinal Cord Injuries D013119 34 associated lipids
Translocation, Genetic D014178 20 associated lipids
Leiomyoma D007889 8 associated lipids
Leukemia, T-Cell D015458 23 associated lipids
Parkinson Disease D010300 53 associated lipids
Glioblastoma D005909 27 associated lipids
Cystitis D003556 23 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Insulin Resistance D007333 99 associated lipids
Per page 10 20 50 100 | Total 64

PubChem Associated disorders and diseases

What pathways are associated with apigenin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with apigenin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with apigenin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with apigenin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with apigenin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with apigenin?

Mouse Model

Mouse Model are used in the study 'Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation.' (Nicholas C et al., 2007), Mouse Model are used in the study 'Plant flavonoid apigenin inactivates Akt to trigger apoptosis in human prostate cancer: an in vitro and in vivo study.' (Kaur P et al., 2008) and Mouse Model are used in the study 'Apigenin alleviates the symptoms of Staphylococcus aureus pneumonia by inhibiting the production of alpha-hemolysin.' (Dong J et al., 2013).

Xenograft Model

Xenograft Model are used in the study 'Induction of caspase-dependent, p53-mediated apoptosis by apigenin in human neuroblastoma.' (Torkin R et al., 2005).

Tissue Model

Tissue Model are used in the study 'Dietary phytophenols curcumin, naringenin and apigenin reduce infection-induced inflammatory and contractile pathways in human placenta, foetal membranes and myometrium.' (Lim R et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with apigenin

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Per page 10 20 50 100 | Total 2777
Authors Title Published Journal PubMed Link
Shi S et al. [Evaluation of brain-targeted trendence of scutellarin nasal administration]. 2010 Zhongguo Zhong Yao Za Zhi pmid:21141499
Li K et al. [Study on fragmentation of vitexin and isorhamnetin-3-O-beta-D-rutinoside using electrospray quadrupole time of flight mass spectrometry]. 2011 Zhongguo Zhong Yao Za Zhi pmid:21506419
Jiang Y et al. [Studies on chemical components of Lobelia chinensis]. 2009 Zhongguo Zhong Yao Za Zhi pmid:19445152
Zhao DB et al. [Studies on chemical constituents of Acroptilon repens]. 2006 Zhongguo Zhong Yao Za Zhi pmid:17285986
Wang LS et al. [Study on the chemical constituents from Picria fel-tarrae]. 2004 Zhongguo Zhong Yao Za Zhi pmid:15719682
Tian J et al. [Studies on the chemical constitutents in herb of Verbena officinalis]. 2005 Zhongguo Zhong Yao Za Zhi pmid:15724402
Qin S and Wen X [Simultaneous determination of 6 active components in Chrysanthemum morifolium by HPLC]. 2011 Zhongguo Zhong Yao Za Zhi pmid:22779181
He CH et al. [Study on intestinal absorption kinetics of apigenin in rats]. 2013 Zhongguo Zhong Yao Za Zhi pmid:23944080
Li XB et al. [Simultaneous determination of chlorogenic acid, scutellarin, 3,5-dicaffeoylquinic acid, 4,5-dicaffeoylquinic acid in different parts of Erigeron breviscapus by high-performance liquid chromatography]. 2013 Zhongguo Zhong Yao Za Zhi pmid:24199546
Zheng XX et al. [Role of ERK/FoxO3a signal axis in inhibitory effect of vitexin 1 (VB-1) in HepG2 cell proliferation]. 2014 Zhongguo Zhong Yao Za Zhi pmid:25011268