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Insights into novel anticancer applications for apigenin. |
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Adv Clin Exp Med |
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Anthoxanthin Polyphenols Attenuate Aβ Oligomer-induced Neuronal Responses Associated with Alzheimer's Disease. |
2017 |
CNS Neurosci Ther |
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Apigenin's anticancer properties and molecular mechanisms of action: Recent advances and future prospectives. |
2017 |
Chin J Nat Med |
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J. Proteome Res. |
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Bioinformatics and in vitro experimental analyses identify the selective therapeutic potential of interferon gamma and apigenin against cervical squamous cell carcinoma and adenocarcinoma. |
2017 |
Oncotarget |
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Apigenin attenuates patulin-induced apoptosis in HEK293 cells by modulating ROS-mediated mitochondrial dysfunction and caspase signal pathway. |
2017 |
Toxicon |
pmid:28734981
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Elhennawy MG and Lin HS |
Quantification of apigenin trimethyl ether in rat plasma by liquid chromatography-tandem mass spectrometry: Application to a pre-clinical pharmacokinetic study. |
2017 |
J Pharm Biomed Anal |
pmid:28494337
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Alvin JW and Lacy DB |
Clostridium difficile toxin glucosyltransferase domains in complex with a non-hydrolyzable UDP-glucose analogue. |
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J. Struct. Biol. |
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Vitexin protects against hypoxic-ischemic injury via inhibiting Ca2+/Calmodulin-dependent protein kinase II and apoptosis signaling in the neonatal mouse brain. |
2017 |
Oncotarget |
pmid:28424420
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Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells. |
2017 |
Geroscience |
pmid:28378188
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The antiproliferative and apoptotic effects of apigenin on glioblastoma cells. |
2017 |
J. Pharm. Pharmacol. |
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Scutellarin protects against doxorubicin-induced acute cardiotoxicity and regulates its accumulation in the heart. |
2017 |
Arch. Pharm. Res. |
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Protective role of apigenin on rotenone induced rat model of Parkinson's disease: Suppression of neuroinflammation and oxidative stress mediated apoptosis. |
2017 |
Chem. Biol. Interact. |
pmid:28389404
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Naik PM and Al-Khayri JM |
Extraction and Estimation of Secondary Metabolites from Date Palm Cell Suspension Cultures. |
2017 |
Methods Mol. Biol. |
pmid:28755356
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Grigalius I and Petrikaite V |
Relationship between Antioxidant and Anticancer Activity of Trihydroxyflavones. |
2017 |
Molecules |
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Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death. |
2017 |
J. Exp. Clin. Cancer Res. |
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Metabolites identificaion of two bioactive constituents in Trollius ledebourii in rats using ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry. |
2017 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
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2017 |
Tumour Biol. |
pmid:29022496
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Molecular targets of vitexin and isovitexin in cancer therapy: a critical review. |
2017 |
Ann. N. Y. Acad. Sci. |
pmid:28891090
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Apigenin inhibits d-galactosamine/LPS-induced liver injury through upregulation of hepatic Nrf-2 and PPARγ expressions in mice. |
2017 |
Biochem. Biophys. Res. Commun. |
pmid:28867192
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Apigenin Restrains Colon Cancer Cell Proliferation via Targeted Blocking of Pyruvate Kinase M2-Dependent Glycolysis. |
2017 |
J. Agric. Food Chem. |
pmid:28829588
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Apigenin prevents ultraviolet-B radiation induced cyclobutane pyrimidine dimers formation in human dermal fibroblasts. |
2017 |
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pmid:28735741
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An Efficient Method for the Preparative Isolation and Purification of Flavonoids from Leaves of Crataegus pinnatifida by HSCCC and Pre-HPLC. |
2017 |
Molecules |
pmid:28486427
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Jangdey MS et al. |
Fabrication, in-vitro characterization, and enhanced in-vivo evaluation of carbopol-based nanoemulsion gel of apigenin for UV-induced skin carcinoma. |
2017 |
Drug Deliv |
pmid:28687053
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Pharmacological stimulation of nuclear factor (erythroid-derived 2)-like 2 translation activates antioxidant responses. |
2017 |
J. Biol. Chem. |
pmid:28684421
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Intranasal administration of brain-targeted HP-β-CD/chitosan nanoparticles for delivery of scutellarin, a compound with protective effect in cerebral ischaemia. |
2017 |
J. Pharm. Pharmacol. |
pmid:28809432
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Fallatah O and Georges E |
Apigenin-induced ABCC1-mediated efflux of glutathione from mature erythrocytes inhibits the proliferation of Plasmodium falciparum. |
2017 |
Int. J. Antimicrob. Agents |
pmid:28807879
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Che Ahmad Tantowi NA et al. |
Mistletoe fig (Ficus deltoidea Jack) leaf extract prevented postmenopausal osteoarthritis by attenuating inflammation and cartilage degradation in rat model. |
2017 |
Menopause |
pmid:28640163
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Perspectives of traditional Chinese medicine in pancreas protection for acute pancreatitis. |
2017 |
World J. Gastroenterol. |
pmid:28611514
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Chen JL and Ko WC |
Relaxation of isolated guinea-pig trachea by apigenin, a constituent of celery, via inhibition of phosphodiesterase. |
2017 |
Eur. J. Pharmacol. |
pmid:28603044
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Correlating In Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids. |
2017 |
Planta Med. |
pmid:28288492
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Vitexin alleviates ox-LDL-mediated endothelial injury by inducing autophagy via AMPK signaling activation. |
2017 |
Mol. Immunol. |
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Apigenin inhibits proliferation and invasion, and induces apoptosis and cell cycle arrest in human melanoma cells. |
2017 |
Oncol. Rep. |
pmid:28260058
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2017 |
J. Inorg. Biochem. |
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Apigenin alleviates STZ-induced diabetic cardiomyopathy. |
2017 |
Mol. Cell. Biochem. |
pmid:28176247
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Comparative pharmacokinetic profiles of selected irreversible tyrosine kinase inhibitors, neratinib and pelitinib, with apigenin in rat plasma by UPLC-MS/MS. |
2017 |
J Pharm Biomed Anal |
pmid:28167419
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Activation of TRPV4 by dietary apigenin antagonizes renal fibrosis in deoxycorticosterone acetate (DOCA)-salt-induced hypertension. |
2017 |
Clin. Sci. |
pmid:28143892
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Combined in Vitro Cell-Based/in Silico Screening of Naturally Occurring Flavonoids and Phenolic Compounds as Potential Anti-Alzheimer Drugs. |
2017 |
J. Nat. Prod. |
pmid:28128562
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Apigenin inhibits cell proliferation, migration, and invasion by targeting Akt in the A549 human lung cancer cell line. |
2017 |
Anticancer Drugs |
pmid:28125432
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The natural flavonoid apigenin sensitizes human CD44 prostate cancer stem cells to cisplatin therapy. |
2017 |
Biomed. Pharmacother. |
pmid:28107698
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Thirusangu P et al. |
Scutellarein antagonizes the tumorigenesis by modulating cytokine VEGF mediated neoangiogenesis and DFF-40 actuated nucleosomal degradation. |
2017 |
Biochem. Biophys. Res. Commun. |
pmid:28104392
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Apigenin potentiates the antitumor activity of 5-FU on solid Ehrlich carcinoma: Crosstalk between apoptotic and JNK-mediated autophagic cell death platforms. |
2017 |
Toxicol. Appl. Pharmacol. |
pmid:28025107
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Uptake of phenolic compounds from plant foods in human intestinal Caco-2 cells. |
2017 |
J. Biosci. |
pmid:29229878
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Tseng TH et al. |
Inhibition of MDA-MB-231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation-mediated p21 expression. |
2017 |
Environ. Toxicol. |
pmid:26872304
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Wu CY et al. |
Scutellarin Attenuates Microglia-Mediated Neuroinflammation and Promotes Astrogliosis in Cerebral Ischemia - A Therapeutic Consideration. |
2017 |
Curr. Med. Chem. |
pmid:27855618
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Guo TT et al. |
Bioactive spirans and other constituents from the leaves of Cannabis sativa f. sativa. |
2017 |
J Asian Nat Prod Res |
pmid:27848262
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Elucidation of Antiangiogenic Potential of Vitexin Obtained from Cucumis sativus Targeting Hsp90 Protein: A Novel Multipathway Targeted Approach to Restrain Angiogenic Phenomena. |
2017 |
Med Chem |
pmid:27834134
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Tang D et al. |
Pharmacokinetic properties and drug interactions of apigenin, a natural flavone. |
2017 |
Expert Opin Drug Metab Toxicol |
pmid:27766890
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Wong TY et al. |
Apigenin and luteolin display differential hypocholesterolemic mechanisms in mice fed a high-fat diet. |
2017 |
Biomed. Pharmacother. |
pmid:29198743
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Salazar-Aguilar S et al. |
Sechium edule (Jacq.) Swartz, a New Cultivar with Antiproliferative Potential in a Human Cervical Cancer HeLa Cell Line. |
2017 |
Nutrients |
pmid:28757593
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