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In vitro-assessment of putative antiprogestin activities of phytochemicals and synthetic UV absorbers in human endometrial Ishikawa cells. |
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Apigenin inhibits the proliferation and invasion of osteosarcoma cells by suppressing the Wnt/β-catenin signaling pathway. |
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Xenobiotica |
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J Sep Sci |
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Vitexin protects brain against ischemia/reperfusion injury via modulating mitogen-activated protein kinase and apoptosis signaling in mice. |
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Phytomedicine |
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Design, synthesis and evaluation of scutellarein-O-alkylamines as multifunctional agents for the treatment of Alzheimer's disease. |
2015 |
Eur J Med Chem |
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Clinical tolerability and pharmacokinetics of Erigerontis hydroxybenzene injection: results of a randomized phase I study in healthy Chinese volunteers. |
2015 |
Phytomedicine |
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Apigenin and Breast Cancers: From Chemistry to Medicine. |
2015 |
Anticancer Agents Med Chem |
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Scutellarin protects against the liver injury induced by diosbulbin B in mice and its mechanism. |
2015 |
J Ethnopharmacol |
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Apigenin inhibits PMA-induced expression of pro-inflammatory cytokines and AP-1 factors in A549 cells. |
2015 |
Mol. Cell. Biochem. |
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Compounds isolated from the aerial part of Crataegus azarolus inhibit growth of B16F10 melanoma cells and exert a potent inhibition of the melanin synthesis. |
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Biomed. Pharmacother. |
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Intestinal anti-inflammatory activity of apigenin K in two rat colitis models induced by trinitrobenzenesulfonic acid and dextran sulphate sodium. |
2015 |
Br. J. Nutr. |
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Haematological and histopathological effects of apigenin, phloretin and myricetin based on uterotrophic assay in immature Wistar female albino rats. |
2015 |
Hum Exp Toxicol |
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Flavan hetero-dimers in the Cymbopogon citratus infusion tannin fraction and their contribution to the antioxidant activity. |
2015 |
Food Funct |
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Dietary apigenin reduces LPS-induced expression of miR-155 restoring immune balance during inflammation. |
2015 |
Mol Nutr Food Res |
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Studies on the interaction of apigenin with calf thymus DNA by spectroscopic methods. |
2015 |
Spectrochim Acta A Mol Biomol Spectrosc |
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Antimicrobial and antioxidant flavonoids from the leaves of Oncoba spinosa Forssk. (Salicaceae). |
2015 |
BMC Complement Altern Med |
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Unusual C,O-Fused Glycosylapigenins from Serjania marginata Leaves. |
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J. Nat. Prod. |
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Anti-angiogenic activity of Entada africana root. |
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Nat. Prod. Res. |
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Activity of the dietary flavonoid, apigenin, against multidrug-resistant tumor cells as determined by pharmacogenomics and molecular docking. |
2015 |
J. Nutr. Biochem. |
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Flavonoid nanocrystals produced by ARTcrystal®-technology. |
2015 |
Int J Pharm |
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2015 |
Phytother Res |
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Apigenin manipulates the ubiquitin-proteasome system to rescue estrogen receptor-β from degradation and induce apoptosis in prostate cancer cells. |
2015 |
Eur J Nutr |
pmid:25408199
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Apigenin inhibits the self-renewal capacity of human ovarian cancer SKOV3‑derived sphere-forming cells. |
2015 |
Mol Med Rep |
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Apigenin inhibits TGF-β1-induced proliferation and migration of airway smooth muscle cells. |
2015 |
Int J Clin Exp Pathol |
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2015 |
Cardiovasc. Toxicol. |
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Infusions of artichoke and milk thistle represent a good source of phenolic acids and flavonoids. |
2015 |
Food Funct |
pmid:25367590
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Flavones inhibit breast cancer proliferation through the Akt/FOXO3a signaling pathway. |
2015 |
BMC Cancer |
pmid:26675309
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5-Fluorouracil combined with apigenin enhances anticancer activity through mitochondrial membrane potential (ΔΨm)-mediated apoptosis in hepatocellular carcinoma. |
2015 |
Clin. Exp. Pharmacol. Physiol. |
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Apigenin Attenuates Melanoma Cell Migration by Inducing Anoikis through Integrin and Focal Adhesion Kinase Inhibition. |
2015 |
Molecules |
pmid:26633318
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Apigenin inhibits migration and invasion via modulation of epithelial mesenchymal transition in prostate cancer. |
2015 |
Mol Med Rep |
pmid:25351792
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Apigenin inhibits HeLa sphere-forming cells through inactivation of casein kinase 2α. |
2015 |
Mol Med Rep |
pmid:25334018
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A novel gas chromatographic method for determination of malondialdehyde from oxidized DNA. |
2015 |
Methods Mol. Biol. |
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Luteolin and Apigenin Attenuate 4-Hydroxy-2-Nonenal-Mediated Cell Death through Modulation of UPR, Nrf2-ARE and MAPK Pathways in PC12 Cells. |
2015 |
PLoS ONE |
pmid:26087007
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Polymethoxyflavone Apigenin-Trimethylether Suppresses LPS-Induced Inflammatory Response in Nontransformed Porcine Intestinal Cell Line IPEC-J2. |
2015 |
Oxid Med Cell Longev |
pmid:26180592
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Apigenin inhibits the proliferation of adenoid cystic carcinoma via suppression of glucose transporter-1. |
2015 |
Mol Med Rep |
pmid:26300442
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The Identification of Maize and Arabidopsis Type I FLAVONE SYNTHASEs Links Flavones with Hormones and Biotic Interactions. |
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Plant Physiol. |
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Anti-Proliferative Effect of Rosmarinus officinalis L. Extract on Human Melanoma A375 Cells. |
2015 |
PLoS ONE |
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Apigenin inhibits indoxyl sulfate-induced endoplasmic reticulum stress and anti-proliferative pathways, CHOP and IL-6/p21, in human renal proximal tubular cells. |
2015 |
Eur Rev Med Pharmacol Sci |
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Apigenin induces dermal collagen synthesis via smad2/3 signaling pathway. |
2015 |
Eur J Histochem |
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Comparative Metabolomic Analysis of the Neuroprotective Effects of Scutellarin and Scutellarein against Ischemic Insult. |
2015 |
PLoS ONE |
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Acylation of Antioxidant of Bamboo Leaves with Fatty Acids by Lipase and the Acylated Derivatives' Efficiency in the Inhibition of Acrylamide Formation in Fried Potato Crisps. |
2015 |
PLoS ONE |
pmid:26098744
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Simultaneous determination of oleanolic acid, ursolic acid, quercetin and apigenin in Swertia mussotii Franch by capillary zone electrophoresis with running buffer modifier. |
2015 |
Biomed. Chromatogr. |
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Flavones Inhibit LPS-Induced Atrogin-1/MAFbx Expression in Mouse C2C12 Skeletal Myotubes. |
2015 |
J. Nutr. Sci. Vitaminol. |
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Dadheech N et al. |
Swertisin an Anti-Diabetic Compound Facilitate Islet Neogenesis from Pancreatic Stem/Progenitor Cells via p-38 MAP Kinase-SMAD Pathway: An In-Vitro and In-Vivo Study. |
2015 |
PLoS ONE |
pmid:26047129
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A new and efficient synthesis of 6-O-methylscutellarein, the major metabolite of the natural medicine scutellarin. |
2015 |
Molecules |
pmid:26042857
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Biosynthesis of Two Flavones, Apigenin and Genkwanin, in Escherichia coli. |
2015 |
J. Microbiol. Biotechnol. |
pmid:25975614
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Oxidative stress triggered by naturally occurring flavone apigenin results in senescence and chemotherapeutic effect in human colorectal cancer cells. |
2015 |
Redox Biol |
pmid:25965143
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Apigenin Attenuates Atherogenesis through Inducing Macrophage Apoptosis via Inhibition of AKT Ser473 Phosphorylation and Downregulation of Plasminogen Activator Inhibitor-2. |
2015 |
Oxid Med Cell Longev |
pmid:25960827
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Regulatory nodD1 and nodD2 genes of Rhizobium tropici strain CIAT 899 and their roles in the early stages of molecular signaling and host-legume nodulation. |
2015 |
BMC Genomics |
pmid:25880529
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Protective effects of scutellarin on type II diabetes mellitus-induced testicular damages related to reactive oxygen species/Bcl-2/Bax and reactive oxygen species/microcirculation/staving pathway in diabetic rat. |
2015 |
J Diabetes Res |
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Pharmacokinetic drug interactions between apigenin, rutin and paclitaxel mediated by P-glycoprotein in rats. |
2015 |
Eur J Drug Metab Pharmacokinet |
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Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo. |
2015 |
Int. J. Mol. Med. |
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Isolation of a flavonoid, apigenin 7-O-glucoside, from Mentha longifolia (L.) Hudson subspecies longifolia and its genotoxic potency. |
2015 |
Toxicol Ind Health |
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The velamen protects photosynthetic orchid roots against UV-B damage, and a large dated phylogeny implies multiple gains and losses of this function during the Cenozoic. |
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New Phytol. |
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Cytotoxic activity of the methanolic extract of Turnera diffusa Willd on breast cancer cells. |
2015 |
J Med Food |
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GRID and docking analyses reveal a molecular basis for flavonoid inhibition of Src family kinase activity. |
2015 |
J. Nutr. Biochem. |
pmid:26140983
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In vitro effects of some flavones on human pyruvate kinase isoenzyme M2. |
2015 |
J. Biochem. Mol. Toxicol. |
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Dietary polyphenols regulate endothelial function and prevent cardiovascular disease. |
2015 |
Nutrition |
pmid:25466651
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Deep Sequencing Reveals the Effect of MeJA on Scutellarin Biosynthesis in Erigeron breviscapus. |
2015 |
PLoS ONE |
pmid:26656917
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Decreased Expression of Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Leads to Reduced Glucuronidation of Flavonoids in UGT1A1-Overexpressing HeLa Cells: The Role of Futile Recycling. |
2015 |
J. Agric. Food Chem. |
pmid:26066637
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Separation of vitexin-4″-O-glucoside and vitexin-2″-O-rhamnoside from hawthorn leaves extracts using macroporous resins. |
2015 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:26562804
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Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment. |
2015 |
J. Nat. Prod. |
pmid:26529431
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Synthesis and biological evaluation of methylated scutellarein analogs based on metabolic mechanism of scutellarin in vivo. |
2015 |
Eur J Med Chem |
pmid:26523667
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Anti-inflammatory effects of vicenin-2 and scolymoside in vitro and in vivo. |
2015 |
Inflamm. Res. |
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Potential role of vitexin in alleviating heat stress-induced cytotoxicity: Regulatory effect of Hsp90 on ER stress-mediated autophagy. |
2015 |
Life Sci. |
pmid:26475763
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Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5. |
2015 |
Bioorg. Med. Chem. Lett. |
pmid:26471090
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Thrombin-induced IL-8/CXCL8 release is mediated by CK2, MSK1, and NF-κB pathways in human lung epithelial cells. |
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Eur. J. Pharmacol. |
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Synthesis of scutellarein derivatives to increase biological activity and water solubility. |
2015 |
Bioorg. Med. Chem. |
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Stable knock-down of efflux transporters leads to reduced glucuronidation in UGT1A1-overexpressing HeLa cells: the evidence for glucuronidation-transport interplay. |
2015 |
Mol. Pharm. |
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Inhibiting GLUT-1 expression and PI3K/Akt signaling using apigenin improves the radiosensitivity of laryngeal carcinoma in vivo. |
2015 |
Oncol. Rep. |
pmid:26238658
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Involvenflavones A-F, six new flavonoids with 3'-aryl substituent from Selaginella involven. |
2015 |
Fitoterapia |
pmid:26226107
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Inhibitory Effect of Apigenin on Pharmacokinetics of Venlafaxine in vivo and in vitro. |
2015 |
Pharmacology |
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Vitexin reduces hypoxia-ischemia neonatal brain injury by the inhibition of HIF-1alpha in a rat pup model. |
2015 |
Neuropharmacology |
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Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein. |
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