| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Astrocytoma | D001254 | 15 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
apigenin
apigenin is a lipid of Polyketides (PK) class. Apigenin is associated with abnormalities such as Morphologically altered structure, Chimera disorder, Hypertensive disease, infection induced and Infection. The involved functions are known as inhibitors, Gene Expression, Process, Metabolic Inhibition and Cell Death. Apigenin often locates in Vacuole, Cytoplasmic matrix, Cytoplasm, Tissue membrane and Membrane. The associated genes with apigenin are MSMP gene, BCL2 gene, PTGS2 gene, Chromatin and SLC33A1 gene. The related lipids are Lipopolysaccharides, Steroids, 1-Butanol, agosterol A and Butyrates. The related experimental models are Mouse Model, Tissue Model, Knock-out, Xenograft Model and Disease model.
Cross Reference
Introduction
To understand associated biological information of apigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with apigenin?
apigenin is suspected in Pneumonia, Morphologically altered structure, Hypertensive disease, Dermatitis, Infection, Senile Plaques and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with apigenin
PubChem Associated disorders and diseases
What pathways are associated with apigenin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with apigenin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with apigenin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with apigenin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with apigenin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with apigenin?
Mouse Model
Mouse Model are used in the study 'Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation.' (Nicholas C et al., 2007), Mouse Model are used in the study 'Plant flavonoid apigenin inactivates Akt to trigger apoptosis in human prostate cancer: an in vitro and in vivo study.' (Kaur P et al., 2008) and Mouse Model are used in the study 'Apigenin alleviates the symptoms of Staphylococcus aureus pneumonia by inhibiting the production of alpha-hemolysin.' (Dong J et al., 2013).
Xenograft Model
Xenograft Model are used in the study 'Induction of caspase-dependent, p53-mediated apoptosis by apigenin in human neuroblastoma.' (Torkin R et al., 2005).
Tissue Model
Tissue Model are used in the study 'Dietary phytophenols curcumin, naringenin and apigenin reduce infection-induced inflammatory and contractile pathways in human placenta, foetal membranes and myometrium.' (Lim R et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with apigenin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sang SM et al. | [Studies on the flavonol glycosides from the seeds of Vaccaria segetalis]. | 2000 | Zhongguo Zhong Yao Za Zhi | pmid:12512436 |
| Zhang WD et al. | [Studies on flavone constituents of Erigeron breviscapus (Vant.) Hand.-Mazz]. | 2000 | Zhongguo Zhong Yao Za Zhi | pmid:12516462 |
| Zhang J et al. | [Studies on chemical constituents of leaves of Salix matsudana Koidz and their influence on lipolysis]. | 2000 | Zhongguo Zhong Yao Za Zhi | pmid:12516463 |
| Gu L et al. | [Quality specification of Perillae Fructus]. | 2010 | Zhongguo Zhong Yao Za Zhi | pmid:21046735 |
| Yuan K et al. | [Simultaneous determination of four glycosylflavones from Lophatherum gracile by RP-HPLC]. | 2008 | Zhongguo Zhong Yao Za Zhi | pmid:19166010 |
| Wang D et al. | [Studies on chemical constituents from herbs of Botrychium lanuginosum]. | 2008 | Zhongguo Zhong Yao Za Zhi | pmid:19216157 |
| Liu J and Xiong Y | [Advances in studies on pharmacokinetics of scutellarin and scutellarein]. | 2009 | Zhongguo Zhong Yao Za Zhi | pmid:20352990 |
| Zhao DB et al. | [Studies on flavonoids from herb of Artemisia ordosica]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16381463 |
| You HS et al. | [Pharmacokinetic and tissue distribution study of scutellarin in rats]. | 2007 | Zhongguo Zhong Yao Za Zhi | pmid:18027669 |
| Liu Z et al. | [Determination of orientin and vitexin in Trollius chinesis preparation by HPLC]. | 2004 | Zhongguo Zhong Yao Za Zhi | pmid:15656135 |
| Zhao DB et al. | [Studies on chemical constituents in herb of Chondrilla piptocoma]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16011281 |
| Che QM et al. | [Study on bile excretion of scutellarein]. | 2006 | Zhongguo Zhong Yao Za Zhi | pmid:17225543 |
| He Y et al. | [Simultaneous determination of chlorogenic acid and vitexin 2"-rhamnoside in Crataegi Fructus extracts by HPLC]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:22715732 |
| Li YR et al. | [Quality standard study on Vigna radiata]. | 2014 | Zhongguo Zhong Yao Za Zhi | pmid:24754176 |
| Pang LL et al. | [Inhibitory effects of apigenin on the expression of GATA-3 and Th2 cytokines in asthmatic mice]. | 2010 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:20669675 |
| Guo LL et al. | [Effect of scutellarin on expressions of nicotinic acetylcholine receptor protein and mRNA in the brains of dementia rats]. | 2011 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:21823425 |
| Tian Y et al. | [The effect of apigenin on reproductive axis in female rats]. | 2011 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | pmid:21845881 |
| Cehn YS et al. | [Studies on the lowering blood sugar substances from agrimony (II)]. | 2010 | Zhong Yao Cai | pmid:20873555 |
| Wang JL et al. | [Studies on the chemical constituents of Pharbitis purpurea]. | 2010 | Zhong Yao Cai | pmid:21355193 |
| Chen J et al. | [Study on chemical constituents of Cardiospermum halicacabum]. | 2013 | Zhong Yao Cai | pmid:23901648 |