| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Cystitis | D003556 | 23 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
FLAVONE
FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.
Cross Reference
Introduction
To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with FLAVONE?
FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with FLAVONE
PubChem Associated disorders and diseases
What pathways are associated with FLAVONE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with FLAVONE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with FLAVONE?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with FLAVONE?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with FLAVONE?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with FLAVONE?
Knock-out
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with FLAVONE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen HJ et al. | Determination of phenolic acids and flavonoids in Taraxacum formosanum Kitam by liquid chromatography-tandem mass spectrometry coupled with a post-column derivatization technique. | 2012 | Int J Mol Sci | pmid:22312251 |
| Kim S et al. | Vascular disrupting agent drug classes differ in effects on the cytoskeleton. | 2012 | PLoS ONE | pmid:22848372 |
| Joshi SC and Mathela CS | Antioxidant and antibacterial activities of the leaf essential oil and its constituents furanodienone and curzerenone from Lindera pulcherrima (Nees.) Benth. ex hook. f. | 2012 | Pharmacognosy Res | pmid:22518079 |
| Chantarudee A et al. | Chemical constituents and free radical scavenging activity of corn pollen collected from Apis mellifera hives compared to floral corn pollen at Nan, Thailand. | 2012 | BMC Complement Altern Med | pmid:22513008 |
| Soumyanath A et al. | Centella asiatica Extract Improves Behavioral Deficits in a Mouse Model of Alzheimer's Disease: Investigation of a Possible Mechanism of Action. | 2012 | Int J Alzheimers Dis | pmid:22506133 |
| Watts SD et al. | A sensitive membrane-targeted biosensor for monitoring changes in intracellular chloride in neuronal processes. | 2012 | PLoS ONE | pmid:22506078 |
| Li Y et al. | [Simultaneous determination of five active components in resina draconis and its extract by HPLC]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:22792791 |
| Balboni G et al. | Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22487176 |
| Zandi K et al. | Flavone enhances dengue virus type-2 (NGC strain) infectivity and replication in vero cells. | 2012 | Molecules | pmid:22374315 |
| Kim HG et al. | Acacetin protects dopaminergic cells against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neuroinflammation in vitro and in vivo. | 2012 | Biol. Pharm. Bull. | pmid:22863927 |
| Zielińska D et al. | Evaluation of flavonoid contents and antioxidant capacity of the aerial parts of common and tartary buckwheat plants. | 2012 | Molecules | pmid:22890171 |
| Engelbertz J et al. | Bioassay-guided fractionation of a thymol-deprived hydrophilic thyme extract and its antispasmodic effect. | 2012 | J Ethnopharmacol | pmid:22465593 |
| Sharma M et al. | Expression of flavonoid 3'-hydroxylase is controlled by P1, the regulator of 3-deoxyflavonoid biosynthesis in maize. | 2012 | BMC Plant Biol. | pmid:23113982 |
| Hammoud L et al. | A new flavonoid and other constituents from Centaurea nicaeensis All. var. walliana M. | 2012 | Nat. Prod. Res. | pmid:21815723 |
| Berim A et al. | A set of regioselective O-methyltransferases gives rise to the complex pattern of methoxylated flavones in sweet basil. | 2012 | Plant Physiol. | pmid:22923679 |
| Seki N et al. | Tricin inhibits proliferation of human hepatic stellate cells in vitro by blocking tyrosine phosphorylation of PDGF receptor and its signaling pathways. | 2012 | J. Cell. Biochem. | pmid:22359269 |
| Shi Y et al. | Analgesic and uterine relaxant effects of isoliquiritigenin, a flavone from Glycyrrhiza glabra. | 2012 | Phytother Res | pmid:22389128 |
| Mijangos MV et al. | Microwave-assisted C-3 selective oxidative radical alkylation of flavones. | 2012 | Org. Biomol. Chem. | pmid:22395456 |
| Patel CA et al. | Remedial Prospective of Hippophae rhamnoides Linn. (Sea Buckthorn). | 2012 | ISRN Pharmacol | pmid:22530142 |
| Huang WY et al. | Survey of antioxidant capacity and phenolic composition of blueberry, blackberry, and strawberry in Nanjing. | 2012 | J Zhejiang Univ Sci B | pmid:22302422 |