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The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice. |
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Br. J. Cancer |
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A novel combretastatin A-4 derivative, AC7700, strongly stanches tumour blood flow and inhibits growth of tumours developing in various tissues and organs. |
2002 |
Br. J. Cancer |
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Induction of endothelial cell apoptosis by the antivascular agent 5,6-Dimethylxanthenone-4-acetic acid. |
2002 |
Br. J. Cancer |
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Interactions of flavones and other phytochemicals with adenosine receptors. |
2002 |
Adv. Exp. Med. Biol. |
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Activation of the antitumor agent aminoflavone (NSC 686288) is mediated by induction of tumor cell cytochrome P450 1A1/1A2. |
2002 |
Mol. Pharmacol. |
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Hadjokas NE et al. |
Arginine to lysine 108 substitution in recombinant CYP1A2 abolishes methoxyresorufin metabolism in lymphoblastoid cells. |
2002 |
Br. J. Pharmacol. |
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Chalcones and flavonoids as anti-tuberculosis agents. |
2002 |
Bioorg. Med. Chem. |
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Relationship between estrogen receptor-binding and estrogenic activities of environmental estrogens and suppression by flavonoids. |
2002 |
Biosci. Biotechnol. Biochem. |
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Activation of bone sialoprotein gene transcription by flavonoids is mediated through an inverted CCAAT box in ROS 17/2.8 cells. |
2002 |
J. Cell. Biochem. |
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Matsui T et al. |
Luteolin, a flavone, does not suppress postprandial glucose absorption through an inhibition of alpha-glucosidase action. |
2002 |
Biosci. Biotechnol. Biochem. |
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A straightforward means of coupling preparative high-performance liquid chromatography and mass spectrometry. |
2002 |
Rapid Commun. Mass Spectrom. |
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Refinement and evaluation of a pharmacophore model for flavone derivatives binding to the benzodiazepine site of the GABA(A) receptor. |
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J. Med. Chem. |
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Self-modelling analysis applied to nanosecond transient absorption spectroscopy of flavone: an aid to elucidate and characterise reaction intermediates. |
2002 |
Spectrochim Acta A Mol Biomol Spectrosc |
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Cytotoxic flavonoids from the stem bark of Lonchocarpus aff. fluvialis. |
2002 |
Phytother Res |
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Flavones from Scutellaria baicalensis Georgi attenuate apoptosis and protein oxidation in neuronal cell lines. |
2002 |
Biochim. Biophys. Acta |
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Interactions of different phenolic acids and flavonoids with soy proteins. |
2002 |
Int. J. Biol. Macromol. |
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Fang J and Beattie DS |
Novel FMN-containing rotenone-insensitive NADH dehydrogenase from Trypanosoma brucei mitochondria: isolation and characterization. |
2002 |
Biochemistry |
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Flavonoids as anticancer agents: structure-activity relationship study. |
2002 |
Curr Med Chem Anticancer Agents |
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Cook SA and Shiemke AK |
Evidence that a type-2 NADH:quinone oxidoreductase mediates electron transfer to particulate methane monooxygenase in methylococcus capsulatus. |
2002 |
Arch. Biochem. Biophys. |
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Flavonolignan and flavone inhibitors of a Staphylococcus aureus multidrug resistance pump: structure-activity relationships. |
2001 |
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Neutral fluorescence probe with strong ratiometric response to surface charge of phospholipid membranes. |
2001 |
FEBS Lett. |
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The flavonoid baicalin inhibits superantigen-induced inflammatory cytokines and chemokines. |
2001 |
FEBS Lett. |
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Determination of flavone, flavonol, and flavanone aglycones by negative ion liquid chromatography electrospray ion trap mass spectrometry. |
2001 |
J. Am. Soc. Mass Spectrom. |
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Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to the eradication of large tumors and multiple tumor foci. |
2001 |
Cancer Res. |
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Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds. |
2001 |
J. Biol. Chem. |
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Antithrombotic effects of flavonoid. |
2001 |
Circulation |
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Influence of natural and synthetic compounds on cell surface expression of cell adhesion molecules, ICAM-1 and VCAM-1. |
2001 |
Planta Med. |
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Effects of simple aromatic compounds and flavonoids on Ca2+ fluxes in rat pituitary GH(4)C(1) cells. |
2001 |
Eur. J. Pharmacol. |
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Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens. |
2001 |
Chem. Res. Toxicol. |
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Beneficial effects of different flavonoids, on functional recovery after ischemia and reperfusion in isolated rat heart. |
2001 |
Bioorg. Med. Chem. Lett. |
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Inhibition of TPA-induced cyclooxygenase-2 expression and skin inflammation in mice by wogonin, a plant flavone from Scutellaria radix. |
2001 |
Eur. J. Pharmacol. |
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Modulation by insulin rather than blood glucose of the pain threshold in acute physiological and flavone induced antinociception in mice. |
2001 |
Indian J. Exp. Biol. |
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Effect of wogonin, a plant flavone from Scutellaria radix, on the suppression of cyclooxygenase-2 and the induction of inducible nitric oxide synthase in lipopolysaccharide-treated RAW 264.7 cells. |
2001 |
Biochem. Pharmacol. |
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Andrade-Cetto A and Wiedenfeld H |
Hypoglycemic effect of Cecropia obtusifolia on streptozotocin diabetic rats. |
2001 |
J Ethnopharmacol |
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Synthesis, antiplatelet and vasorelaxing effects of monooxygenated flavones and flavonoxypropanolamines. |
2001 |
J. Pharm. Pharmacol. |
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Measurement of plasma 5-hydroxyindoleacetic acid as a possible clinical surrogate marker for the action of antivascular agents. |
2001 |
Clin. Chim. Acta |
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Flavonol and flavone intake and the risk of cancer in male smokers (Finland). |
2001 |
Cancer Causes Control |
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Biflavonoids from Ouratea multiflora. |
2001 |
Fitoterapia |
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Synthesis of flavonoids and their effects on aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues. |
2001 |
J. Pharm. Pharmacol. |
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A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17 alpha-hydroxylase/C17,20-lyase. |
2001 |
J. Med. Chem. |
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Molecular modeling and QSAR analysis of the interaction of flavone derivatives with the benzodiazepine binding site of the GABA(A) receptor complex. |
2001 |
Bioorg. Med. Chem. |
pmid:11249125
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The ABC-like vacuolar transporter for rye mesophyll flavone glucuronides is not species-specific. |
2001 |
Phytochemistry |
pmid:11219807
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Biological properties of citrus flavonoids pertaining to cancer and inflammation. |
2001 |
Curr. Med. Chem. |
pmid:11172671
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Dertinger SD et al. |
Aryl hydrocarbon receptor signaling plays a significant role in mediating benzo[a]pyrene- and cigarette smoke condensate-induced cytogenetic damage in vivo. |
2001 |
Carcinogenesis |
pmid:11159756
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Hirvonen T et al. |
Intake of flavonols and flavones and risk of coronary heart disease in male smokers. |
2001 |
Epidemiology |
pmid:11138821
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Inhibitory effects of naturally occurring compounds on aflatoxin B(1) biotransformation. |
2001 |
J. Agric. Food Chem. |
pmid:11714299
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Covalent alteration of the CYP3A4 active site: evidence for multiple substrate binding domains. |
2001 |
Arch. Biochem. Biophys. |
pmid:11414684
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3D-QSAR model of flavonoids binding at benzodiazepine site in GABAA receptors. |
2001 |
J. Med. Chem. |
pmid:11384234
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Velázquez I and Pardo JP |
Kinetic characterization of the rotenone-insensitive internal NADH: ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiae. |
2001 |
Arch. Biochem. Biophys. |
pmid:11370674
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Rossi M et al. |
Molecular structure and activity toward DNA of baicalein, a flavone constituent of the Asian herbal medicine "Sho-saiko-to". |
2001 |
J. Nat. Prod. |
pmid:11170661
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