| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lymphedema | D008209 | 4 associated lipids |
| Neoplasms, Experimental | D009374 | 10 associated lipids |
| Encephalitis | D004660 | 15 associated lipids |
| Neoplasm Invasiveness | D009361 | 23 associated lipids |
| Cystitis | D003556 | 23 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
FLAVONE
FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.
Cross Reference
Introduction
To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with FLAVONE?
FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with FLAVONE
PubChem Associated disorders and diseases
What pathways are associated with FLAVONE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with FLAVONE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with FLAVONE?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with FLAVONE?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with FLAVONE?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with FLAVONE?
Knock-out
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with FLAVONE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Galindo P et al. | Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation. | 2012 | PLoS ONE | pmid:22427863 |
| Lee DH et al. | Flavonoids Isolated from Korea Citrus aurantium L. Induce G2/M Phase Arrest and Apoptosis in Human Gastric Cancer AGS Cells. | 2012 | Evid Based Complement Alternat Med | pmid:22194772 |
| Lee H et al. | Angelicae Dahuricae Radix Inhibits Dust Mite Extract-Induced Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice. | 2012 | Evid Based Complement Alternat Med | pmid:22454682 |
| Wang J et al. | Rapid Screening for Flavone C-Glycosides in the Leaves of Different Species of Bamboo and Simultaneous Quantitation of Four Marker Compounds by HPLC-UV/DAD. | 2012 | Int J Anal Chem | pmid:22654910 |
| Bairwa R et al. | Trachyspermum ammi. | 2012 | Pharmacogn Rev | pmid:22654405 |
| Liu Y et al. | Chinese herb and formulas for promoting blood circulation and removing blood stasis and antiplatelet therapies. | 2012 | Evid Based Complement Alternat Med | pmid:22454656 |
| Yong-Chun J et al. | A novel high-performance liquid chromatography fingerprint approach to discriminate Phyllostachys pubescens from China. | 2012 | Pharmacogn Mag | pmid:22438662 |
| Zamboni A et al. | Genome-wide microarray analysis of tomato roots showed defined responses to iron deficiency. | 2012 | BMC Genomics | pmid:22433273 |
| Khan R et al. | Chrysin protects against cisplatin-induced colon. toxicity via amelioration of oxidative stress and apoptosis: probable role of p38MAPK and p53. | 2012 | Toxicol. Appl. Pharmacol. | pmid:22155348 |
| Chen YH et al. | Evaluation of the structure-activity relationship of flavonoids as antioxidants and toxicants of zebrafish larvae. | 2012 | Food Chem | pmid:23107683 |
| Christensen KY et al. | The risk of lung cancer related to dietary intake of flavonoids. | 2012 | Nutr Cancer | pmid:23061904 |
| Hatnapure GD et al. | Synthesis and biological evaluation of novel piperazine derivatives of flavone as potent anti-inflammatory and antimicrobial agent. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22981334 |
| Hamilton ML et al. | Elucidation of the biosynthesis of the di-C-glycosylflavone isoschaftoside, an allelopathic component from Desmodium spp. that inhibits Striga spp. development. | 2012 | Phytochemistry | pmid:22959223 |
| de-Faria FM et al. | Antioxidant action of mangrove polyphenols against gastric damage induced by absolute ethanol and ischemia-reperfusion in the rat. | 2012 | ScientificWorldJournal | pmid:22654592 |
| Kongkum N et al. | DNA topoisomerase IIα inhibitory and anti-HIV-1 flavones from leaves and twigs of Gardenia carinata. | 2012 | Fitoterapia | pmid:22155186 |
| Buchanan CM et al. | DMXAA (Vadimezan, ASA404) is a multi-kinase inhibitor targeting VEGFR2 in particular. | 2012 | Clin. Sci. | pmid:22142330 |
| Rahigude A et al. | Participation of antioxidant and cholinergic system in protective effect of naringenin against type-2 diabetes-induced memory dysfunction in rats. | 2012 | Neuroscience | pmid:22999973 |
| Kostrzewa-Susłow E and Janeczko T | Microbial transformations of 7-hydroxyflavanone. | 2012 | ScientificWorldJournal | pmid:22654578 |
| Xie C et al. | The açaà flavonoid velutin is a potent anti-inflammatory agent: blockade of LPS-mediated TNF-α and IL-6 production through inhibiting NF-κB activation and MAPK pathway. | 2012 | J. Nutr. Biochem. | pmid:22137267 |
| Palmieri D et al. | Apigenin inhibits the TNFα-induced expression of eNOS and MMP-9 via modulating Akt signalling through oestrogen receptor engagement. | 2012 | Mol. Cell. Biochem. | pmid:22899172 |