FLAVONE

FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.

Cross Reference

Introduction

To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with FLAVONE?

FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with FLAVONE

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Asthma D001249 52 associated lipids
Body Weight D001835 333 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Cystitis D003556 23 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Edema D004487 152 associated lipids
Encephalitis D004660 15 associated lipids
Glioma D005910 112 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hypertension D006973 115 associated lipids
Leukemia P388 D007941 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with FLAVONE

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with FLAVONE?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with FLAVONE?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with FLAVONE?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with FLAVONE?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with FLAVONE?

Knock-out

Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Disease model

Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Animal Disease Models

Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with FLAVONE

Download all related citations
Per page 10 20 50 100 | Total 1492
Authors Title Published Journal PubMed Link
Borges-Argáez R et al. Cytotoxic and antiprotozoal activity of flavonoids from Lonchocarpus spp. 2007 Phytomedicine pmid:17291734
Flemmig J et al. Olea europaea leaf (Ph.Eur.) extract as well as several of its isolated phenolics inhibit the gout-related enzyme xanthine oxidase. 2011 Phytomedicine pmid:21144719
Garritano S et al. Assessment of estrogenic activity of flavonoids from Mediterranean plants using an in vitro short-term test. 2005 Phytomedicine pmid:15693722
Julião Lde S et al. Flavones and phenylpropanoids from a sedative extract of Lantana trifolia L. 2010 Phytochemistry pmid:19922967
Yamada K et al. A lipase inhibitor monoterpene and monoterpene glycosides from Monarda punctata. 2010 Phytochemistry pmid:20832830
Bredebach M et al. Three 2-oxoglutarate-dependent dioxygenase activities of Equisetum arvense L. forming flavone and flavonol from (2S)-naringenin. 2011 Phytochemistry pmid:21353683
Jahaniani F et al. Xanthomicrol is the main cytotoxic component of Dracocephalum kotschyii and a potential anti-cancer agent. 2005 Phytochemistry pmid:15949825
Bjorøy O et al. C-glycosylanthocyanidins synthesized from C-glycosylflavones. 2009 Phytochemistry pmid:19185884
Mori M et al. Cyanosalvianin, a supramolecular blue metalloanthocyanin, from petals of Salvia uliginosa. 2008 Phytochemistry pmid:18466933
Ruberto G and Tringali C Secondary metabolites from the leaves of Feijoa sellowiana Berg. 2004 Phytochemistry pmid:15501265
Duarte-Almeida JM et al. Antiproliferative and antioxidant activities of a tricin acylated glycoside from sugarcane (Saccharum officinarum) juice. 2007 Phytochemistry pmid:17350657
Meng Y et al. Flavones and flavone glycosides from Halophila johnsonii. 2008 Phytochemistry pmid:18771781
Ngadjui BT et al. Prenylated chalcones, flavone and other constituents of the twigs of Dorstenia angusticornis and Dorstenia barteri var. subtriangularis. 2005 Phytochemistry pmid:15771891
Vieira RF et al. Chemical profiling of Ocimum americanum using external flavonoids. 2003 Phytochemistry pmid:12809716
Reddy MK et al. A flavone and an unusual 23-carbon terpenoid from Andrographis paniculata. 2003 Phytochemistry pmid:12648550
Budzianowski J et al. Lipophilic flavones of Primula veris L. from field cultivation and in vitro cultures. 2005 Phytochemistry pmid:15896373
Hamilton ML et al. Elucidation of the biosynthesis of the di-C-glycosylflavone isoschaftoside, an allelopathic component from Desmodium spp. that inhibits Striga spp. development. 2012 Phytochemistry pmid:22959223
Saracoglu I et al. Acylated flavonoids and phenol glycosides from Veronica thymoides subsp. pseudocinerea. 2004 Phytochemistry pmid:15381011
Fukui Y et al. A rationale for the shift in colour towards blue in transgenic carnation flowers expressing the flavonoid 3',5'-hydroxylase gene. 2003 Phytochemistry pmid:12657292
Veitch NC et al. Flavonoid glycosides of the black locust tree, Robinia pseudoacacia (Leguminosae). 2010 Phytochemistry pmid:19948349