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Direct semi-synthesis of the anticancer lead-drug protoapigenone from apigenin, and synthesis of further new cytotoxic protoflavone derivatives. |
2011 |
PLoS ONE |
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Vitcheva V et al. |
Hepatoprotective effects of saponarin, isolated from Gypsophila trichotoma Wend. on cocaine-induced oxidative stress in rats. |
2011 |
Redox Rep. |
pmid:21722413
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Wang Y et al. |
Screening Antitumor Compounds Psoralen and Isopsoralen from Psoralea corylifolia L. Seeds. |
2011 |
Evid Based Complement Alternat Med |
pmid:19131395
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Duan K et al. |
LC-MS/MS determination and pharmacokinetic study of five flavone components after solvent extraction/acid hydrolysis in rat plasma after oral administration of Verbena officinalis L. extract. |
2011 |
J Ethnopharmacol |
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Lakshmi C et al. |
Antibacterial activity of polyphenols of garcinia indica. |
2011 |
Indian J Pharm Sci |
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Sancho MI et al. |
Spectroscopic study of solvent effects on the electronic absorption spectra of flavone and 7-hydroxyflavone in neat and binary solvent mixtures. |
2011 |
Int J Mol Sci |
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Kothandan G et al. |
Docking and 3D-QSAR (quantitative structure activity relationship) studies of flavones, the potent inhibitors of p-glycoprotein targeting the nucleotide binding domain. |
2011 |
Eur J Med Chem |
pmid:21723648
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Ibrahim MH et al. |
Effects of nitrogen fertilization on synthesis of primary and secondary metabolites in three varieties of Kacip Fatimah (Labisia pumila Blume). |
2011 |
Int J Mol Sci |
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Vila-Real H et al. |
Enzymatic Synthesis of the Flavone Glucosides, Prunin and Isoquercetin, and the Aglycones, Naringenin and Quercetin, with Selective α-L-Rhamnosidase and β-D-Glucosidase Activities of Naringinase. |
2011 |
Enzyme Res |
pmid:21941631
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Bhavsar AS et al. |
A review on recent advances in dry eye: Pathogenesis and management. |
2011 |
Oman J Ophthalmol |
pmid:21897618
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Tahanian E et al. |
Flavonoids targeting of IκB phosphorylation abrogates carcinogen-induced MMP-9 and COX-2 expression in human brain endothelial cells. |
2011 |
Drug Des Devel Ther |
pmid:21625419
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Subbarao PG and Ashok P |
Antihyperlipidemic effect of Trichilia connaroides in hypercholesterolemic rats and its possible mechanism. |
2011 |
J Pharm Bioallied Sci |
pmid:21687351
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Quintão NL et al. |
Aleurites moluccana (L.) Willd. Leaves: Mechanical Antinociceptive Properties of a Standardized Dried Extract and Its Chemical Markers. |
2011 |
Evid Based Complement Alternat Med |
pmid:21660087
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Guo AJ et al. |
Baicalin, a flavone, induces the differentiation of cultured osteoblasts: an action via the Wnt/beta-catenin signaling pathway. |
2011 |
J. Biol. Chem. |
pmid:21652696
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Nerurkar PV et al. |
Momordica charantia (bitter melon) attenuates high-fat diet-associated oxidative stress and neuroinflammation. |
2011 |
J Neuroinflammation |
pmid:21639917
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Seo S et al. |
Cyanide, a coproduct of plant hormone ethylene biosynthesis, contributes to the resistance of rice to blast fungus. |
2011 |
Plant Physiol. |
pmid:21075959
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Wootten D et al. |
Modulation of the glucagon-like peptide-1 receptor signaling by naturally occurring and synthetic flavonoids. |
2011 |
J. Pharmacol. Exp. Ther. |
pmid:21075839
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Xia EQ et al. |
Microwave-assisted extraction of oleanolic acid and ursolic acid from Ligustrum lucidum Ait. |
2011 |
Int J Mol Sci |
pmid:21954361
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Lewin G et al. |
Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
2011 |
Bioorg. Med. Chem. |
pmid:21146994
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Flemmig J et al. |
Olea europaea leaf (Ph.Eur.) extract as well as several of its isolated phenolics inhibit the gout-related enzyme xanthine oxidase. |
2011 |
Phytomedicine |
pmid:21144719
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Jiang DP et al. |
Effects of scutellarin on MUC5AC mucin production induced by human neutrophil elastase or interleukin 13 on airway epithelial cells. |
2011 |
J. Korean Med. Sci. |
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Enomoto R et al. |
Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects. |
2011 |
Cancer Chemother. Pharmacol. |
pmid:20658136
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Varma A et al. |
Andrographolide: a new plant-derived antineoplastic entity on horizon. |
2011 |
Evid Based Complement Alternat Med |
pmid:19752167
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Xue L et al. |
Pd-carbene catalyzed carbonylation reactions of aryl iodides. |
2011 |
Dalton Trans |
pmid:21677940
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Schumacher M et al. |
Potential role of P-gp for flavone-induced diminished apoptosis and increased adenoma size in the small intestine of APC(min/+) mice. |
2011 |
Cancer Invest. |
pmid:21649465
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Said SA |
Two new special flavones from Uvaria accuminata. |
2011 |
Nat. Prod. Res. |
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Seo J et al. |
Flavonoids biotransformation by bacterial non-heme dioxygenases, biphenyl and naphthalene dioxygenase. |
2011 |
Appl. Microbiol. Biotechnol. |
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Boyle SP et al. |
Evaluation of quality control strategies in Scutellaria herbal medicines. |
2011 |
J Pharm Biomed Anal |
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Cai WJ et al. |
Icariin and its derivative icariside II extend healthspan via insulin/IGF-1 pathway in C. elegans. |
2011 |
PLoS ONE |
pmid:22216122
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Derdemezis CS et al. |
Effect of Plant Polyphenols on Adipokine Secretion from Human SGBS Adipocytes. |
2011 |
Biochem Res Int |
pmid:21949907
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Mafuvadze B et al. |
Apigenin blocks induction of vascular endothelial growth factor mRNA and protein in progestin-treated human breast cancer cells. |
2010 Sep-Oct |
Menopause |
pmid:20551847
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Marczak Å et al. |
Fragmentation pathways of acylated flavonoid diglucuronides from leaves of Medicago truncatula. |
2010 May-Jun |
Phytochem Anal |
pmid:19950391
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Acharya A et al. |
Redox regulation in cancer: a double-edged sword with therapeutic potential. |
2010 Jan-Feb |
Oxid Med Cell Longev |
pmid:20716925
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Carneiro CD et al. |
Effect of flavonoids on 2'-deoxyguanosine and DNA oxidation caused by singlet molecular oxygen. |
2010 Aug-Sep |
Food Chem. Toxicol. |
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Julião Lde S et al. |
Flavones and phenylpropanoids from a sedative extract of Lantana trifolia L. |
2010 |
Phytochemistry |
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Flavone C-glycosides from seeds of fenugreek, Trigonella foenum-graecum L. |
2010 |
J. Agric. Food Chem. |
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Identification of chalcones as in vivo liver monofunctional phase II enzymes inducers. |
2010 |
Bioorg. Med. Chem. |
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Zhao C et al. |
[Study on extraction of anti-diabetes active constituents from Potentilla chinesis]. |
2010 |
Zhong Yao Cai |
pmid:20575426
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Phenolic Glycosides with antiproteasomal activity from Centaurea urvillei DC. subsp. urvillei. |
2010 |
Carbohydr. Res. |
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Flavone induces changes in intermediary metabolism that prevent microadenoma formation in colonic tissue of carcinogen-treated mice. |
2010 |
Mol Nutr Food Res |
pmid:20564477
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Hirai S et al. |
Functional food targeting the regulation of obesity-induced inflammatory responses and pathologies. |
2010 |
Mediators Inflamm. |
pmid:20508825
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Bioavailability of the polyphenols: status and controversies. |
2010 |
Int J Mol Sci |
pmid:20480022
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Kuete V and Efferth T |
Cameroonian medicinal plants: pharmacology and derived natural products. |
2010 |
Front Pharmacol |
pmid:21833168
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Chatuphonprasert W et al. |
Potent modification of inducible CYP1A1 expression by flavonoids. |
2010 |
Biol. Pharm. Bull. |
pmid:20930378
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Kundu S and Roy D |
Structural study of biologically significant ligands with major birch pollen allergen Betv1 by docking and molecular dynamics simulation. |
2010 |
Bioinformation |
pmid:20978606
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Jayaraman P et al. |
Activity and interactions of antibiotic and phytochemical combinations against Pseudomonas aeruginosa in vitro. |
2010 |
Int. J. Biol. Sci. |
pmid:20941374
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Mukai R et al. |
Suppression mechanisms of flavonoids on aryl hydrocarbon receptor-mediated signal transduction. |
2010 |
Arch. Biochem. Biophys. |
pmid:20450880
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Yen JH et al. |
Glycine tomentella Hayata inhibits IL-1β and IL-6 production, inhibits MMP-9 activity, and enhances RAW264.7 macrophage clearance of apoptotic cells. |
2010 |
J. Biomed. Sci. |
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Meng X et al. |
Effects of Various Flavonoids on the α-Synuclein Fibrillation Process. |
2010 |
Parkinsons Dis |
pmid:20976092
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Jeng YJ et al. |
Subchronic exposure to phytoestrogens alone and in combination with diethylstilbestrol - pituitary tumor induction in Fischer 344 rats. |
2010 |
Nutr Metab (Lond) |
pmid:20459739
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Ci X et al. |
Regulation of inflammatory mediators in lipopolysaccharide-stimulated RAW 264.7 cells by 2''-hydroxy-3''-en-anhydroicaritin involves down-regulation of NF-kappaB and MAPK expression. |
2010 |
Int. Immunopharmacol. |
pmid:20462523
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Madeira PJ et al. |
Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometric and semi-empirical calculations study of five isoflavone aglycones. |
2010 |
Rapid Commun. Mass Spectrom. |
pmid:21072799
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Shimada T et al. |
Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives. |
2010 |
Chem. Res. Toxicol. |
pmid:21053930
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Sasaki K et al. |
Functional divergence within class B MADS-box genes TfGLO and TfDEF in Torenia fournieri Lind. |
2010 |
Mol. Genet. Genomics |
pmid:20872230
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Zhang Y et al. |
Dietary flavonol and flavone intakes and their major food sources in Chinese adults. |
2010 |
Nutr Cancer |
pmid:21058200
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Kumar GS et al. |
Synthesis and biological evaluation of novel benzyl-substituted flavones as free radical (DPPH) scavengers and α-glucosidase inhibitors. |
2010 |
J Asian Nat Prod Res |
pmid:21061220
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Flavanols and anthocyanins in cardiovascular health: a review of current evidence. |
2010 |
Int J Mol Sci |
pmid:20480037
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Treutter D |
Managing phenol contents in crop plants by phytochemical farming and breeding-visions and constraints. |
2010 |
Int J Mol Sci |
pmid:20479987
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Huang CH et al. |
Natural flavone kaempferol suppresses chemokines expression in human monocyte THP-1 cells through MAPK pathways. |
2010 |
J. Food Sci. |
pmid:21535503
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Xu B and Chang SK |
Phenolic substance characterization and chemical and cell-based antioxidant activities of 11 lentils grown in the northern United States. |
2010 |
J. Agric. Food Chem. |
pmid:20058926
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Attimarad M |
Liquid Chromatographic Determination of Flavoxate HCl in Pharmaceutical Formulation. |
2010 |
J Young Pharm |
pmid:21042486
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Charkoudian LK et al. |
In living color: bacterial pigments as an untapped resource in the classroom and beyond. |
2010 |
PLoS Biol. |
pmid:20957190
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Lakhan SE and Vieira KF |
Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review. |
2010 |
Nutr J |
pmid:20929532
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Demiroglu-Zergeroglu A et al. |
The investigation of effects of quercetin and its combination with Cisplatin on malignant mesothelioma cells in vitro. |
2010 |
J. Biomed. Biotechnol. |
pmid:20508819
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Fransen HP et al. |
Assessment of health claims, content, and safety of herbal supplements containing Ginkgo biloba. |
2010 |
Food Nutr Res |
pmid:20927202
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Suttana W et al. |
Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols. |
2010 |
Mol. Cancer |
pmid:20438634
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Chen CC et al. |
Calcium- and phosphatidylinositol 3-kinase/Akt-dependent activation of endothelial nitric oxide synthase by apigenin. |
2010 |
Life Sci. |
pmid:21034748
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Gao LM and Meléndez E |
Cytotoxic properties of titanocenyl amides on breast cancer cell line mcf-7. |
2010 |
Met Based Drugs |
pmid:20454639
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Kyrgidis A et al. |
Melanoma: Stem cells, sun exposure and hallmarks for carcinogenesis, molecular concepts and future clinical implications. |
2010 |
J Carcinog |
pmid:20442802
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Zhuang P et al. |
Effects of flavone on the oxidation-induced injury of retinal pigment epithelium cells. |
2010 |
Int J Ophthalmol |
pmid:22553529
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Zhuang P et al. |
Effect of flavone on the ocular blood flow and formation of choroidal neovascularization. |
2010 |
Int J Ophthalmol |
pmid:22553528
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Semalty M et al. |
Semecarpus anacardium Linn.: A review. |
2010 |
Pharmacogn Rev |
pmid:22228947
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Wera M et al. |
2-(4-Fluoro-phen-yl)-3-hy-droxy-4H-chromen-4-one. |
2010 |
Acta Crystallogr Sect E Struct Rep Online |
pmid:21589426
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van Tonder JH et al. |
Racemic tricarbonyl[(4a,5,6,7,8,8a-η)-2-phenyl-3,4-dihydro-2H-1-benzopyran]chromium(0). |
2010 |
Acta Crystallogr Sect E Struct Rep Online |
pmid:21588503
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Baikar S and Malpathak N |
Secondary metabolites as DNA topoisomerase inhibitors: A new era towards designing of anticancer drugs. |
2010 |
Pharmacogn Rev |
pmid:22228937
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Dirscherl K et al. |
Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype. |
2010 |
J Neuroinflammation |
pmid:20074346
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Valdameri G et al. |
Importance of the core structure of flavones in promoting inhibition of the mitochondrial respiratory chain. |
2010 |
Chem. Biol. Interact. |
pmid:20654598
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Hanhineva K et al. |
Impact of dietary polyphenols on carbohydrate metabolism. |
2010 |
Int J Mol Sci |
pmid:20480025
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Dobritsa AA et al. |
LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis. |
2010 |
Plant Physiol. |
pmid:20442277
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Hong TB et al. |
Potential effects of chrysin on MDA-MB-231 cells. |
2010 |
Int J Mol Sci |
pmid:20479999
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Perumal Samy R and Gopalakrishnakone P |
Therapeutic Potential of Plants as Anti-microbials for Drug Discovery. |
2010 |
Evid Based Complement Alternat Med |
pmid:18955349
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Lakshmi V et al. |
Antifilarial activity in vitro and in vivo of some flavonoids tested against Brugia malayi. |
2010 |
Acta Trop. |
pmid:20609356
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Yang Y et al. |
Binding research on flavones as ligands of β-amyloid aggregates by fluorescence and their 3D-QSAR, docking studies. |
2010 |
J. Mol. Graph. Model. |
pmid:21094069
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Baguley BC and McKeage MJ |
ASA404: a tumor vascular-disrupting agent with broad potential for cancer therapy. |
2010 |
Future Oncol |
pmid:21062153
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Shaker E et al. |
Anti-inflammatory and anti-ulcer activity of the extract from Alhagi maurorum (camelthorn). |
2010 |
Food Chem. Toxicol. |
pmid:20633591
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Gautam N et al. |
In-situ absorption, protein binding and pharmacokinetic studies of S002-853, a novel antidiabetic and antidyslipidaemic flavone derivative in rats. |
2010 |
J. Pharm. Pharmacol. |
pmid:20609062
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Cesla P et al. |
Separation of phenolic acids and flavone natural antioxidants by two-dimensional method combining liquid chromatography and micellar electrokinetic capillary chromatography. |
2010 |
Electrophoresis |
pmid:20593394
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Fan Y et al. |
Epimedium polysaccharide and propolis flavone can synergistically stimulate lymphocyte proliferation in vitro and enhance the immune responses to ND vaccine in chickens. |
2010 |
Int. J. Biol. Macromol. |
pmid:20562020
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Liu XH et al. |
Synthesis and molecular docking studies of novel 2-chloro-pyridine derivatives containing flavone moieties as potential antitumor agents. |
2010 |
Bioorg. Med. Chem. Lett. |
pmid:20538457
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Tian Y et al. |
Anti-HBV active flavone glucosides from Euphorbia humifusa Willd. |
2010 |
Fitoterapia |
pmid:20450964
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Hori A and Naganuma K |
Fully and partially fluorinated flavone derivatives. |
2010 |
Acta Crystallogr C |
pmid:20442510
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Guendel I et al. |
Inhibition of human immunodeficiency virus type-1 by cdk inhibitors. |
2010 |
AIDS Res Ther |
pmid:20334651
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Yashiroda Y et al. |
A novel yeast cell-based screen identifies flavone as a tankyrase inhibitor. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20214890
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Ramful D et al. |
Bioactive phenolics and antioxidant propensity of flavedo extracts of Mauritian citrus fruits: potential prophylactic ingredients for functional foods application. |
2010 |
Toxicology |
pmid:20100535
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Echeverry C et al. |
Pretreatment with natural flavones and neuronal cell survival after oxidative stress: a structure-activity relationship study. |
2010 |
J. Agric. Food Chem. |
pmid:20095615
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Bacher M et al. |
Complete 1H and 13C NMR data assignment of new constituents from Severinia buxifolia. |
2010 |
Magn Reson Chem |
pmid:19937908
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Jandera P et al. |
Dual hydrophilic interaction-RP retention mechanism on polar columns: structural correlations and implementation for 2-D separations on a single column. |
2010 |
J Sep Sci |
pmid:20087874
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Kasai N et al. |
Atypical kinetics of cytochromes P450 catalysing 3'-hydroxylation of flavone from the white-rot fungus Phanerochaete chrysosporium. |
2010 |
J. Biochem. |
pmid:19819902
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Rajesh G et al. |
Effect of hydroxyl substitution of flavone on angiogenesis and free radical scavenging activities: a structure-activity relationship studies using computational tools. |
2010 |
Eur J Pharm Sci |
pmid:19874890
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Veitch NC et al. |
Flavonoid glycosides of the black locust tree, Robinia pseudoacacia (Leguminosae). |
2010 |
Phytochemistry |
pmid:19948349
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