Bibby MC et al. |
Unique chemosensitivity of MAC 16 tumours to flavone acetic acid (LM975, NSC 347512). |
1988 |
Br. J. Cancer |
pmid:3179187
|
Bibby MC et al. |
Experimental anti-tumor effects of flavone acetic acid (LM975). |
1988 |
Prog. Clin. Biol. Res. |
pmid:3174695
|
Weiss RB et al. |
Phase I and clinical pharmacology study of intravenous flavone acetic acid (NSC 347512). |
1988 |
Cancer Res. |
pmid:3167843
|
Pratesi G et al. |
Response of chemically induced primary colon tumours of the mouse to flavone acetic acid (NSC 347 512). |
1988 |
Br. J. Cancer |
pmid:3166904
|
Yamazoe Y et al. |
Metabolic activation of pyrolysate arylamines by human liver microsomes; possible involvement of a P-488-H type cytochrome P-450. |
1988 |
Jpn. J. Cancer Res. |
pmid:3147272
|
Ohchi H et al. |
Effects of dietary xenobiotics on the metabolism of copper, alpha-tocopherol and cholesterol in rats. |
1987 |
J. Nutr. Sci. Vitaminol. |
pmid:3125311
|
Yamazoe Y et al. |
Metabolic activation of a protein pyrolysate promutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by rat liver microsomes and purified cytochrome P-450. |
1988 |
Carcinogenesis |
pmid:3121205
|
Armand J et al. |
Flavonoids: a new class of anticancer agents? Preclinical and clinical data of flavone acetic acid. |
1988 |
Prog. Clin. Biol. Res. |
pmid:3051027
|
Liu L et al. |
Rational Design for Multicolor Flavone-Based Fluorophores with Aggregation-Induced Emission Enhancement Characteristics and Applications in Mitochondria-Imaging. |
2018 |
Molecules |
pmid:30205485
|
Ngabaza T et al. |
Anti-acidogenic and anti-biofilm activity of 5,6,8-trihydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one. |
2018 |
Microb. Pathog. |
pmid:30008421
|
Nakabo D et al. |
Convenient Synthesis and Physiological Activities of Flavonoids in Coreopsis lanceolata L. Petals and Their Related Compounds. |
2018 |
Molecules |
pmid:29987259
|
Lim H et al. |
Flavonoids interfere with NLRP3 inflammasome activation. |
2018 |
Toxicol. Appl. Pharmacol. |
pmid:29960001
|
Mitra A et al. |
Studies on the interaction of a synthetic nitro-flavone derivative with DNA: A multi-spectroscopic and molecular docking approach. |
2018 |
Spectrochim Acta A Mol Biomol Spectrosc |
pmid:29885634
|
Rahmouni N et al. |
L. Phenolic Content Clarifies Its Antioxidant Activity. |
2018 |
Molecules |
pmid:29861483
|
Bevara GB et al. |
C-glycosyl flavone from inhibits proliferation & angiogenesis & induces apoptosis via cyclin-dependent kinase 6 in human breast, hepatic & colon cancer cell lines. |
2018 |
Indian J. Med. Res. |
pmid:29806604
|
Brauch D et al. |
Changes in isovitexin-O-glycosylation during the development of young barley plants. |
2018 |
Phytochemistry |
pmid:29421507
|
Li XF |
[Effects of flavone II of Piper wallichii on the isolated rabbit heart]. |
1985 |
Zhong Yao Tong Bao |
pmid:2934172
|
Oh JM et al. |
Characterization of two extracellular β-glucosidases produced from the cellulolytic fungus Aspergillus sp. YDJ216 and their potential applications for the hydrolysis of flavone glycosides. |
2018 |
Int. J. Biol. Macromol. |
pmid:29339289
|
Huang L et al. |
Autophagy induction by hispidulin provides protection against sevoflurane-induced neuronal apoptosis in aged rats. |
2018 |
Biomed. Pharmacother. |
pmid:29287193
|
Thangaraj K and Vaiyapuri M |
Orientin, a C-glycosyl dietary flavone, suppresses colonic cell proliferation and mitigates NF-κB mediated inflammatory response in 1,2-dimethylhydrazine induced colorectal carcinogenesis. |
2017 |
Biomed. Pharmacother. |
pmid:29198745
|
Dei S et al. |
Design and synthesis of aminoester heterodimers containing flavone or chromone moieties as modulators of P-glycoprotein-based multidrug resistance (MDR). |
2018 |
Bioorg. Med. Chem. |
pmid:29162309
|
Vetrani C et al. |
Association between different dietary polyphenol subclasses and the improvement in cardiometabolic risk factors: evidence from a randomized controlled clinical trial. |
2018 |
Acta Diabetol |
pmid:29151225
|
Bibby MC et al. |
Reduction of tumor blood flow by flavone acetic acid: a possible component of therapy. |
1989 |
J. Natl. Cancer Inst. |
pmid:2911084
|
Wu ES et al. |
Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
1989 |
J. Med. Chem. |
pmid:2909730
|
Relling MV et al. |
Anticancer drugs as inhibitors of two polymorphic cytochrome P450 enzymes, debrisoquin and mephenytoin hydroxylase, in human liver microsomes. |
1989 |
Cancer Res. |
pmid:2908853
|
Xie H et al. |
Total flavone of Desmodium styracifolium relieved apoptosis and autophagy of COM-induced HK-2 cells by regulating KIM-1 via p38/MAPK pathway. |
2018 |
Mol. Cell. Biochem. |
pmid:29071538
|
Yu FL et al. |
NIR Rapid Assessments of Blumea balsamifera (Ai-na-xiang) in China. |
2017 |
Molecules |
pmid:29035305
|
Chung YC et al. |
Pratol, an O-Methylated Flavone, Induces Melanogenesis in B16F10 Melanoma Cells via p-p38 and p-JNK Upregulation. |
2017 |
Molecules |
pmid:29019920
|
Davis HP et al. |
Immune thrombocytopenia caused by flavone-8-acetic acid. |
1988 |
Lancet |
pmid:2893207
|
Verweij J et al. |
Rapid alkalinisation for flavone acetic acid administration: a potentially hazardous procedure. |
1988 |
Lancet |
pmid:2893206
|
Kamata R et al. |
Agonistic effects of diverse xenobiotics on the constitutive androstane receptor as detected in a recombinant yeast-cell assay. |
2018 |
Toxicol In Vitro |
pmid:28927721
|
Huang QH et al. |
Isoprenylated phenolic compounds with PTP1B inhibition from Morus alba. |
2017 |
Fitoterapia |
pmid:28916258
|
Rubin J et al. |
Flavone-8-acetic acid inhibits ristocetin-induced platelet agglutination and prolongs bleeding time. |
1987 |
Lancet |
pmid:2889983
|
Kim J et al. |
In vitro characterization of CYP102G4 from Streptomyces cattleya: A self-sufficient P450 naturally producing indigo. |
2018 |
Biochim Biophys Acta Proteins Proteom |
pmid:28821467
|
Feng XT et al. |
Protective role of Pollen Typhae total flavone against the palmitic acid-induced impairment of glucose-stimulated insulin secretion involving GPR40 signaling in INS-1 cells. |
2017 |
Int. J. Mol. Med. |
pmid:28731171
|
Miyata Y et al. |
In vitro studies on nobiletin isolated from citrus plants and the bioactive metabolites, inhibitory action against gelatinase enzymatic activity and the molecular mechanisms in human retinal Müller cell line. |
2017 |
Biomed. Pharmacother. |
pmid:28623785
|
Das S et al. |
Antioxidant flavone analog functionalized fluorescent silica nanoparticles: Synthesis and exploration of their possible use as biomolecule sensor. |
2017 |
Colloids Surf B Biointerfaces |
pmid:28601757
|
Al-Rimawi F et al. |
ANALYSIS OF PHENOLIC AND FLAVONOIDS OF WILD EPHEDRA ALATA PLANT EXTRACTS BY LC/PDA AND LC/MS AND THEIR ANTIOXIDANT ACTIVITY. |
2017 |
Afr J Tradit Complement Altern Med |
pmid:28573229
|
Berczyński P et al. |
Synthesis and in vitro antioxidant activity study of some new piperazinyl flavone compounds. |
2017 |
Luminescence |
pmid:28569387
|
Montenegro CA et al. |
In Silico Study and Bioprospection of the Antibacterial and Antioxidant Effects of Flavone and Its Hydroxylated Derivatives. |
2017 |
Molecules |
pmid:28538688
|
Živković JČ et al. |
Chemical Profiling and Assessment of Antineurodegenerative and Antioxidant Properties of Veronica teucrium L. and Veronica jacquinii Baumg. |
2017 |
Chem. Biodivers. |
pmid:28488389
|
Kim S et al. |
Promotion of Glucose Uptake in C2C12 Myotubes by Cereal Flavone Tricin and Its Underlying Molecular Mechanism. |
2017 |
J. Agric. Food Chem. |
pmid:28474889
|
Qu Y et al. |
Expression of Root Genes in Arabidopsis Seedlings Grown by Standard and Improved Growing Methods. |
2017 |
Int J Mol Sci |
pmid:28467358
|
Bourdillat B et al. |
Mechanism of action of hispidulin, a natural flavone, on human platelets. |
1988 |
Prog. Clin. Biol. Res. |
pmid:2845433
|
Corradi E et al. |
Metabolite Profile and Antiproliferative Effects in HaCaT Cells of a Salix reticulata Extract. |
2017 |
Planta Med. |
pmid:28449181
|
An JY et al. |
Identification and structure activity relationship of novel flavone derivatives that inhibit the production of nitric oxide and PGE2 in LPS-induced RAW 264.7 cells. |
2017 |
Bioorg. Med. Chem. Lett. |
pmid:28408221
|
Tsai YF et al. |
6-Hydroxy-5,7-dimethoxy-flavone suppresses the neutrophil respiratory burst via selective PDE4 inhibition to ameliorate acute lung injury. |
2017 |
Free Radic. Biol. Med. |
pmid:28263828
|
Li S et al. |
Chemical profiling of Fufang-Xialian-Capsule by UHPLC-Q-TOF-MS and its antioxidant activity evaluated by in vitro method. |
2017 |
J Pharm Biomed Anal |
pmid:28235732
|
Lonchampt M et al. |
Protective effect of a purified flavonoid fraction against reactive oxygen radicals. In vivo and in vitro study. |
1989 |
Arzneimittelforschung |
pmid:2818676
|
Yang Y et al. |
Encapsulation of Polymethoxyflavones in Citrus Oil Emulsion-Based Delivery Systems. |
2017 |
J. Agric. Food Chem. |
pmid:28182421
|
Li YP et al. |
Three new C-alkylated flavonoids from Desmodium oblongum. |
2017 |
J Asian Nat Prod Res |
pmid:28145124
|
Kang Y et al. |
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain. |
2017 |
Bioorg. Med. Chem. Lett. |
pmid:28049590
|
Murray JC et al. |
Flavone acetic acid induces a coagulopathy in mice. |
1989 |
Br. J. Cancer |
pmid:2803949
|
Kerr DJ et al. |
Phase II trials of flavone acetic acid in advanced malignant melanoma and colorectal carcinoma. |
1989 |
Br. J. Cancer |
pmid:2803908
|
Atwell GJ et al. |
Synthesis and anti-tumour activity of topologically-related analogues of flavoneacetic acid. |
1989 |
Anticancer Drug Des. |
pmid:2803464
|
Kamto EL et al. |
Alternating isocratic and step gradient elution high-speed counter-current chromatography for the isolation of minor phenolics from Ormocarpum kirkii bark. |
2017 |
J Chromatogr A |
pmid:27988077
|
Sun JR and Brown JM |
Enhancement of the antitumor effect of flavone acetic acid by the bioreductive cytotoxic drug SR 4233 in a murine carcinoma. |
1989 |
Cancer Res. |
pmid:2790784
|
Nagai T et al. |
Inhibition of mouse liver sialidase by plant flavonoids. |
1989 |
Biochem. Biophys. Res. Commun. |
pmid:2775264
|
Chabot GG et al. |
Flavone acetic acid (LM-975; NSC-347512) activation to cytotoxic species in vivo and in vitro. |
1989 |
Cancer Chemother. Pharmacol. |
pmid:2758556
|
Ertan R et al. |
Synthesis of new annellated flavonoid derivatives possessing spasmolytic activity--VII. |
1989 |
Arch. Pharm. (Weinheim) |
pmid:2751412
|
Bugel SM et al. |
Comparative Developmental Toxicity of Flavonoids Using an Integrative Zebrafish System. |
2016 |
Toxicol. Sci. |
pmid:27492224
|
Ching LM and Baguley BC |
Effect of flavone acetic acid (NSC 347,512) on splenic cytotoxic effector cells and their role in tumour necrosis. |
1989 |
Eur J Cancer Clin Oncol |
pmid:2737219
|
Roy D and Liehr JG |
Metabolic oxidation of diethylstilbestrol to diethylstilbestrol-4',4"-quinone in Syrian hamsters. |
1989 |
Carcinogenesis |
pmid:2736717
|
Zwi LJ et al. |
Blood flow failure as a major determinant in the antitumor action of flavone acetic acid. |
1989 |
J. Natl. Cancer Inst. |
pmid:2733044
|
Rabinovitz M |
Flavone-8-acetic acid and the natural flavonoids. |
1989 |
J. Natl. Cancer Inst. |
pmid:2733041
|
Bibby MC et al. |
Influence of site on the chemosensitivity of transplantable murine colon tumours to flavone acetic acid (LM975, NSC 347512). |
1989 |
Cancer Chemother. Pharmacol. |
pmid:2731316
|
Cummings J et al. |
Characterization of the major metabolites of flavone acetic acid and comparison of their disposition in humans and mice. |
1989 |
Cancer Res. |
pmid:2731178
|
Yan X et al. |
58-F, a flavanone from Ophiopogon japonicus, prevents hepatocyte death by decreasing lysosomal membrane permeability. |
2016 |
Sci Rep |
pmid:27306715
|
Lan W et al. |
Maize Tricin-Oligolignol Metabolites and Their Implications for Monocot Lignification. |
2016 |
Plant Physiol. |
pmid:27208246
|
Zhao Q et al. |
A specialized flavone biosynthetic pathway has evolved in the medicinal plant, Scutellaria baicalensis. |
2016 |
Sci Adv |
pmid:27152350
|
Cassidy J et al. |
Could interspecies differences in the protein binding of flavone acetic acid contribute to the failure to predict lack of efficacy in patients? |
1989 |
Cancer Chemother. Pharmacol. |
pmid:2713962
|
Lewis CR et al. |
Autonomic neuropathy following treatment with flavone acetic acid. |
1989 |
Eur J Cancer Clin Oncol |
pmid:2703010
|
Baguley BC et al. |
Comparison of the effects of flavone acetic acid, fostriecin, homoharringtonine and tumour necrosis factor alpha on colon 38 tumours in mice. |
1989 |
Eur J Cancer Clin Oncol |
pmid:2702981
|
Lameiras P and Nuzillard JM |
Highly Viscous Binary Solvents: DMSO-d6/Glycerol and DMSO-d6/Glycerol-d8 for Polar and Apolar Mixture Analysis by NMR. |
2016 |
Anal. Chem. |
pmid:27008506
|
Ismail NA and Jusoh SA |
Molecular Docking and Molecular Dynamics Simulation Studies to Predict Flavonoid Binding on the Surface of DENV2 E Protein. |
2017 |
Interdiscip Sci |
pmid:26969331
|
Zhu W et al. |
Flavone inhibits migration through DLC1/RhoA pathway by decreasing ROS generation in breast cancer cells. |
2016 |
In Vitro Cell. Dev. Biol. Anim. |
pmid:26935193
|
Kasala ER et al. |
Chemopreventive effect of chrysin, a dietary flavone against benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice. |
2016 |
Pharmacol Rep |
pmid:26922533
|
Kant R et al. |
Synthesis of newer 1,2,3-triazole linked chalcone and flavone hybrid compounds and evaluation of their antimicrobial and cytotoxic activities. |
2016 |
Eur J Med Chem |
pmid:26922227
|
Wang DJ et al. |
Effect of Total Flavone of Haw Leaves on Nuclear Factor Erythroid-2 Related Factor and Other Related Factors in Nonalcoholic Steatohepatitis Rats. |
2018 |
Chin J Integr Med |
pmid:26919834
|
Kerr DJ and Kaye SB |
Flavone acetic acid--preclinical and clinical activity. |
1989 |
Eur J Cancer Clin Oncol |
pmid:2680512
|
Zhang J et al. |
A flavone-based turn-on fluorescent probe for intracellular cysteine/homocysteine sensing with high selectivity. |
2016 |
Talanta |
pmid:26695232
|
Cummings J and Smyth JF |
Flavone 8-acetic acid: our current understanding of its mechanism of action in solid tumours. |
1989 |
Cancer Chemother. Pharmacol. |
pmid:2667786
|
Lin CH et al. |
Flavones inhibit breast cancer proliferation through the Akt/FOXO3a signaling pathway. |
2015 |
BMC Cancer |
pmid:26675309
|
LeJeune TM et al. |
Mechanism of Action of Two Flavone Isomers Targeting Cancer Cells with Varying Cell Differentiation Status. |
2015 |
PLoS ONE |
pmid:26606169
|
Jian J et al. |
Bauhinia championii flavone inhibits apoptosis and autophagy via the PI3K/Akt pathway in myocardial ischemia/reperfusion injury in rats. |
2015 |
Drug Des Devel Ther |
pmid:26604691
|
Malkhasian AY and Howlin BJ |
Docking and DFT studies on ligand binding to Quercetin 2,3-dioxygenase. |
2016 |
J. Biomol. Struct. Dyn. |
pmid:26599260
|
Li YR et al. |
Tangeretin derivative, 5-acetyloxy-6,7,8,4'-tetramethoxyflavone induces G2/M arrest, apoptosis and autophagy in human non-small cell lung cancer cells in vitro and in vivo. |
2016 |
Cancer Biol. Ther. |
pmid:26569090
|
Imran S et al. |
Synthesis of novel flavone hydrazones: in-vitro evaluation of α-glucosidase inhibition, QSAR analysis and docking studies. |
2015 |
Eur J Med Chem |
pmid:26491979
|
Hao B et al. |
The biosynthesis of allelopathic di-C-glycosylflavones from the roots of Desmodium incanum (G. Mey.) DC. |
2015 |
Org. Biomol. Chem. |
pmid:26478440
|
Zhang F et al. |
Forsythoneosides A-D, Neuroprotective Phenethanoid and Flavone Glycoside Heterodimers from the Fruits of Forsythia suspensa. |
2015 |
J. Nat. Prod. |
pmid:26422318
|
Real Hernandez LM et al. |
Berry Phenolic Compounds Increase Expression of Hepatocyte Nuclear Factor-1α (HNF-1α) in Caco-2 and Normal Colon Cells Due to High Affinities with Transcription and Dimerization Domains of HNF-1α. |
2015 |
PLoS ONE |
pmid:26413797
|
Zhang M et al. |
FlavonQ: an automated data processing tool for profiling flavone and flavonol glycosides with ultra-high-performance liquid chromatography-diode array detection-high resolution accurate mass-mass spectrometry. |
2015 |
Anal. Chem. |
pmid:26359695
|
Fan Y et al. |
The activation of Epimedium polysaccharide-propolis flavone liposome on Kupffer cells. |
2015 |
Carbohydr Polym |
pmid:26344320
|
Zhao W et al. |
Ammonium Iodide Induced Nonradical Regioselective Sulfenylation of Flavones via a C-H Functionalization Process. |
2015 |
J. Org. Chem. |
pmid:26291122
|
Desoize B et al. |
Response of primary tumour, spontaneous metastases and recurrence of Lewis lung carcinoma (3LL) to flavone acetic acid (FAA, LM975). |
1989 Nov-Dec |
Anticancer Res. |
pmid:2627123
|
Yan J et al. |
The soybean R2R3 MYB transcription factor GmMYB100 negatively regulates plant flavonoid biosynthesis. |
2015 |
Plant Mol. Biol. |
pmid:26231207
|
Tranchand B et al. |
[Phase I pharmacokinetics of flavone-acetic acid]. |
1989 |
Bull Cancer |
pmid:2620114
|
Bonnay M et al. |
[Flavone acetic acid and LY 186641 interfere in various ways in Jaffé's reaction]. |
1989 |
Bull Cancer |
pmid:2620109
|
Boesten DM et al. |
Protective Pleiotropic Effect of Flavonoids on NAD⺠Levels in Endothelial Cells Exposed to High Glucose. |
2015 |
Oxid Med Cell Longev |
pmid:26180598
|
Almeida JR et al. |
3,6-Dimethoxy-6″,6″-Dimethyl-(7,8,2″,3″)-Chromeneflavone, a Flavonoid Isolated from Lonchocarpus Araripensis Benth. (Fabaceae), Reduces Nociceptive Behaviour in Mice. |
2015 |
Phytother Res |
pmid:26172339
|