Akao T et al. |
Baicalin, the predominant flavone glucuronide of scutellariae radix, is absorbed from the rat gastrointestinal tract as the aglycone and restored to its original form. |
2000 |
J. Pharm. Pharmacol. |
pmid:11197087
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Tomazela DM et al. |
Pyrano chalcones and a flavone from Neoraputia magnifica and their Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase-inhibitory activities. |
2000 |
Phytochemistry |
pmid:11130676
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Rajendran NN et al. |
Antinociceptive pattern of flavone and its mechanism as tested by formalin assay. |
2000 |
Indian J. Exp. Biol. |
pmid:11218837
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Collins-Burow BM et al. |
Estrogenic and antiestrogenic activities of flavonoid phytochemicals through estrogen receptor binding-dependent and -independent mechanisms. |
2000 |
Nutr Cancer |
pmid:11525602
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Tunçbilek M et al. |
Synthesis and antioxidant properties of some new flavone derivatives on lipid peroxidation in the rat liver. |
2000 |
Pharmazie |
pmid:11828615
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Kulevanova S et al. |
HPLC identification and determination of flavone aglycones in Helichrysum plicatum DC. (Asteraceae). |
2000 |
Pharmazie |
pmid:11828624
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Dertinger SD et al. |
Effect of 3'-methoxy-4'-nitroflavone on benzo[a]pyrene toxicity. Aryl hydrocarbon receptor-dependent and -independent mechanisms. |
2000 |
Biochem. Pharmacol. |
pmid:10825463
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Motwani M et al. |
Flavopiridol, a cyclin-dependent kinase inhibitor, prevents spindle inhibitor-induced endoreduplication in human cancer cells. |
2000 |
Clin. Cancer Res. |
pmid:10741717
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Perez RM et al. |
Isolation and hypoglycemic activity of 5, 7,3'-trihydroxy-3,6,4'-trimethoxyflavone from Brickellia veronicaefolia. |
2000 |
Phytomedicine |
pmid:10782487
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Liu IX et al. |
Baicalin synergy with beta-lactam antibiotics against methicillin-resistant Staphylococcus aureus and other beta-lactam-resistant strains of S. aureus. |
2000 |
J. Pharm. Pharmacol. |
pmid:10757427
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Schwinger RH et al. |
Crataegus special extract WS 1442 increases force of contraction in human myocardium cAMP-independently. |
2000 |
J. Cardiovasc. Pharmacol. |
pmid:10813370
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Sue M et al. |
Purification and characterization of a hydroxamic acid glucoside beta-glucosidase from wheat (Triticum aestivum L.) seedlings. |
2000 |
Planta |
pmid:10750901
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BozdaÄŸ O et al. |
Synthesis and hypoglycemic activity of some new flavone derivatives. 3rd communication: 3'-flavonyl-2,4-thiazolidinediones. |
2000 |
Arzneimittelforschung |
pmid:10965419
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Valenti P et al. |
Synthesis and biological activity of some rigid analogues of flavone-8-acetic acid. |
2000 |
Bioorg. Med. Chem. |
pmid:10968283
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El-Subbagh HI et al. |
Synthesis and biological evaluation of certain alpha,beta-unsaturated ketones and their corresponding fused pyridines as antiviral and cytotoxic agents. |
2000 |
J. Med. Chem. |
pmid:10956199
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La Casa C et al. |
Evidence for protective and antioxidant properties of rutin, a natural flavone, against ethanol induced gastric lesions. |
2000 |
J Ethnopharmacol |
pmid:10904145
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Aitken RA et al. |
Synthesis and antitumour activity of new derivatives of flavone-8-acetic acid (FAA). Part 4: Variation of the basic structure. |
2000 |
Arch. Pharm. (Weinheim) |
pmid:10909190
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Nielsen SE et al. |
Biotransformation of the citrus flavone tangeretin in rats. Identification of metabolites with intact flavane nucleus. |
2000 |
Food Chem. Toxicol. |
pmid:10930694
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Viola H et al. |
6,3'-dibromoflavone and 6-nitro-3'-bromoflavone: new additions to the 6,3'-disubstituted flavone family of high-affinity ligands of the brain benzodiazepine binding site with agonistic properties. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10873666
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BozdaÄŸ O et al. |
Synthesis and hypoglycemic activity of some new flavone derivatives. 2nd communication: 4'-flavonyl-2,4-thiazolidinediones. |
2000 |
Arzneimittelforschung |
pmid:10918947
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Wenzel U et al. |
Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells. |
2000 |
Cancer Res. |
pmid:10919656
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Ramelet AA |
Pharmacologic aspects of a phlebotropic drug in CVI-associated edema. |
2000 |
Angiology |
pmid:10667639
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Viola H et al. |
6-Chloro-3'-nitroflavone is a potent ligand for the benzodiazepine binding site of the GABA(A) receptor devoid of intrinsic activity. |
2000 |
Pharmacol. Biochem. Behav. |
pmid:10672984
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Ma YL et al. |
Internal glucose residue loss in protonated O-diglycosyl flavonoids upon low-energy collision-induced dissociation. |
2000 |
J. Am. Soc. Mass Spectrom. |
pmid:10689666
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Arriaga AM et al. |
Constituents of Bowdichia virgilioides. |
2000 |
Fitoterapia |
pmid:10727826
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Mruk JS et al. |
Flavone-8-acetic acid (Flavonoid) profoundly reduces platelet-dependent thrombosis and vasoconstriction after deep arterial injury In vivo. |
2000 |
Circulation |
pmid:10645930
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da Silva EL et al. |
Inhibitory effect of flavonoids on low-density lipoprotein peroxidation catalyzed by mammalian 15-lipoxygenase. |
2000 |
IUBMB Life |
pmid:10995031
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Wollenweber E et al. |
Epicuticular flavonoids of some Scrophulariaceae. |
2000 Jan-Feb |
Z. Naturforsch., C, J. Biosci. |
pmid:10739092
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Harris SR et al. |
Oxidative stress contributes to the anti-proliferative effects of flavone acetic acid on endothelial cells. |
2000 Jul-Aug |
Anticancer Res. |
pmid:10953282
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Shao ZM et al. |
Genistein's "ER-dependent and independent" actions are mediated through ER pathways in ER-positive breast carcinoma cell lines. |
2000 Jul-Aug |
Anticancer Res. |
pmid:10953303
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Baranowska I and Raróg D |
Application of derivative spectrophotometry to determination of flavonoid mixtures. |
2001 |
Talanta |
pmid:18968363
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Böcker D and Verspohl EJ |
Role of protein kinase C, PI3-kinase and tyrosine kinase in activation of MAP kinase by glucose and agonists of G-protein coupled receptors in INS-1 cells. |
2001 |
Int. J. Exp. Diabetes Res. |
pmid:12369712
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Guz NR et al. |
Flavonolignan and flavone inhibitors of a Staphylococcus aureus multidrug resistance pump: structure-activity relationships. |
2001 |
J. Med. Chem. |
pmid:11170636
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Duportail G et al. |
Neutral fluorescence probe with strong ratiometric response to surface charge of phospholipid membranes. |
2001 |
FEBS Lett. |
pmid:11718715
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Krakauer T et al. |
The flavonoid baicalin inhibits superantigen-induced inflammatory cytokines and chemokines. |
2001 |
FEBS Lett. |
pmid:11434925
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Fabre N et al. |
Determination of flavone, flavonol, and flavanone aglycones by negative ion liquid chromatography electrospray ion trap mass spectrometry. |
2001 |
J. Am. Soc. Mass Spectrom. |
pmid:11401161
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Kanwar JR et al. |
Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to the eradication of large tumors and multiple tumor foci. |
2001 |
Cancer Res. |
pmid:11280751
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Galietta LJ et al. |
Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds. |
2001 |
J. Biol. Chem. |
pmid:11262417
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Goto S and Handa S |
Antithrombotic effects of flavonoid. |
2001 |
Circulation |
pmid:11157735
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Tanaka S et al. |
Influence of natural and synthetic compounds on cell surface expression of cell adhesion molecules, ICAM-1 and VCAM-1. |
2001 |
Planta Med. |
pmid:11301853
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Summanen J et al. |
Effects of simple aromatic compounds and flavonoids on Ca2+ fluxes in rat pituitary GH(4)C(1) cells. |
2001 |
Eur. J. Pharmacol. |
pmid:11239912
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Fang H et al. |
Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens. |
2001 |
Chem. Res. Toxicol. |
pmid:11258977
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Lebeau J et al. |
Beneficial effects of different flavonoids, on functional recovery after ischemia and reperfusion in isolated rat heart. |
2001 |
Bioorg. Med. Chem. Lett. |
pmid:11140725
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Saarinen N et al. |
No evidence for the in vivo activity of aromatase-inhibiting flavonoids. |
2001 |
J. Steroid Biochem. Mol. Biol. |
pmid:11595503
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Park BK et al. |
Inhibition of TPA-induced cyclooxygenase-2 expression and skin inflammation in mice by wogonin, a plant flavone from Scutellaria radix. |
2001 |
Eur. J. Pharmacol. |
pmid:11502282
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Rajendran NN et al. |
Modulation by insulin rather than blood glucose of the pain threshold in acute physiological and flavone induced antinociception in mice. |
2001 |
Indian J. Exp. Biol. |
pmid:11883508
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Kim SJ |
Effect of biflavones of Ginkgo biloba against UVB-induced cytotoxicity in vitro. |
2001 |
J. Dermatol. |
pmid:11449670
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Chi YS et al. |
Effect of wogonin, a plant flavone from Scutellaria radix, on the suppression of cyclooxygenase-2 and the induction of inducible nitric oxide synthase in lipopolysaccharide-treated RAW 264.7 cells. |
2001 |
Biochem. Pharmacol. |
pmid:11322923
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Seo HJ and Surh YJ |
Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces apoptosis in human promyelocytic leukemia cells. |
2001 |
Mutat. Res. |
pmid:11551495
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Andrade-Cetto A and Wiedenfeld H |
Hypoglycemic effect of Cecropia obtusifolia on streptozotocin diabetic rats. |
2001 |
J Ethnopharmacol |
pmid:11694359
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Chung MI et al. |
Synthesis, antiplatelet and vasorelaxing effects of monooxygenated flavones and flavonoxypropanolamines. |
2001 |
J. Pharm. Pharmacol. |
pmid:11804390
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Kestell P et al. |
Measurement of plasma 5-hydroxyindoleacetic acid as a possible clinical surrogate marker for the action of antivascular agents. |
2001 |
Clin. Chim. Acta |
pmid:11718691
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Hirvonen T et al. |
Flavonol and flavone intake and the risk of cancer in male smokers (Finland). |
2001 |
Cancer Causes Control |
pmid:11714106
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Philpott M et al. |
The antitumour agent 5,6-dimethylxanthenone-4-acetic acid acts in vitro on human mononuclear cells as a co-stimulator with other inducers of tumour necrosis factor. |
2001 |
Eur. J. Cancer |
pmid:11576850
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Mcmullen MD et al. |
The biological basis of epistasis between quantitative trait loci for flavone and 3-deoxyanthocyanin synthesis in maize (Zea mays L.). |
2001 |
Genome |
pmid:11550903
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Kumazawa T et al. |
Synthesis of 8-C-glucosylflavones. |
2001 |
Carbohydr. Res. |
pmid:11513825
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Pepper C et al. |
Flavopiridol circumvents Bcl-2 family mediated inhibition of apoptosis and drug resistance in B-cell chronic lymphocytic leukaemia. |
2001 |
Br. J. Haematol. |
pmid:11472347
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MarÃn FR and Del RÃo JA |
Selection of hybrids and edible citrus species with a high content in the diosmin functional compound. Modulating effect of plant growth regulators on contents. |
2001 |
J. Agric. Food Chem. |
pmid:11453775
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D'arc Felicio J et al. |
Biflavonoids from Ouratea multiflora. |
2001 |
Fitoterapia |
pmid:11395278
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Lim SS et al. |
Synthesis of flavonoids and their effects on aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues. |
2001 |
J. Pharm. Pharmacol. |
pmid:11370705
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Recanatini M et al. |
A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17 alpha-hydroxylase/C17,20-lyase. |
2001 |
J. Med. Chem. |
pmid:11262078
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Marder M et al. |
Molecular modeling and QSAR analysis of the interaction of flavone derivatives with the benzodiazepine binding site of the GABA(A) receptor complex. |
2001 |
Bioorg. Med. Chem. |
pmid:11249125
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Klein M et al. |
The ABC-like vacuolar transporter for rye mesophyll flavone glucuronides is not species-specific. |
2001 |
Phytochemistry |
pmid:11219807
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Manthey JA et al. |
Biological properties of citrus flavonoids pertaining to cancer and inflammation. |
2001 |
Curr. Med. Chem. |
pmid:11172671
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Dertinger SD et al. |
Aryl hydrocarbon receptor signaling plays a significant role in mediating benzo[a]pyrene- and cigarette smoke condensate-induced cytogenetic damage in vivo. |
2001 |
Carcinogenesis |
pmid:11159756
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Hirvonen T et al. |
Intake of flavonols and flavones and risk of coronary heart disease in male smokers. |
2001 |
Epidemiology |
pmid:11138821
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Stochmal A et al. |
Acylated apigenin glycosides from alfalfa (Medicago sativa L.) var. Artal. |
2001 |
Phytochemistry |
pmid:11454348
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Lee SE et al. |
Inhibitory effects of naturally occurring compounds on aflatoxin B(1) biotransformation. |
2001 |
J. Agric. Food Chem. |
pmid:11714299
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Schrag ML and Wienkers LC |
Covalent alteration of the CYP3A4 active site: evidence for multiple substrate binding domains. |
2001 |
Arch. Biochem. Biophys. |
pmid:11414684
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Huang X et al. |
3D-QSAR model of flavonoids binding at benzodiazepine site in GABAA receptors. |
2001 |
J. Med. Chem. |
pmid:11384234
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Velázquez I and Pardo JP |
Kinetic characterization of the rotenone-insensitive internal NADH: ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiae. |
2001 |
Arch. Biochem. Biophys. |
pmid:11370674
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Tabak C et al. |
Chronic obstructive pulmonary disease and intake of catechins, flavonols, and flavones: the MORGEN Study. |
2001 |
Am. J. Respir. Crit. Care Med. |
pmid:11435239
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Rossi M et al. |
Molecular structure and activity toward DNA of baicalein, a flavone constituent of the Asian herbal medicine "Sho-saiko-to". |
2001 |
J. Nat. Prod. |
pmid:11170661
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Zhao L et al. |
The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice. |
2002 |
Br. J. Cancer |
pmid:12177785
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Hori K et al. |
A novel combretastatin A-4 derivative, AC7700, strongly stanches tumour blood flow and inhibits growth of tumours developing in various tissues and organs. |
2002 |
Br. J. Cancer |
pmid:12085211
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Ching LM et al. |
Induction of endothelial cell apoptosis by the antivascular agent 5,6-Dimethylxanthenone-4-acetic acid. |
2002 |
Br. J. Cancer |
pmid:12085190
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Jacobson KA et al. |
Interactions of flavones and other phytochemicals with adenosine receptors. |
2002 |
Adv. Exp. Med. Biol. |
pmid:12083460
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Kuffel MJ et al. |
Activation of the antitumor agent aminoflavone (NSC 686288) is mediated by induction of tumor cell cytochrome P450 1A1/1A2. |
2002 |
Mol. Pharmacol. |
pmid:12065765
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Hadjokas NE et al. |
Arginine to lysine 108 substitution in recombinant CYP1A2 abolishes methoxyresorufin metabolism in lymphoblastoid cells. |
2002 |
Br. J. Pharmacol. |
pmid:12023936
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Lin YM et al. |
Chalcones and flavonoids as anti-tuberculosis agents. |
2002 |
Bioorg. Med. Chem. |
pmid:12057669
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Isobe T et al. |
[Antibacterial constituents against Helicobacter pylori of Brazilian medicinal plant, Pariparoba]. |
2002 |
Yakugaku Zasshi |
pmid:11968842
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Po LS et al. |
Baicalein and genistein display differential actions on estrogen receptor (ER) transactivation and apoptosis in MCF-7 cells. |
2002 |
Cancer Lett. |
pmid:12359348
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Han DH et al. |
Relationship between estrogen receptor-binding and estrogenic activities of environmental estrogens and suppression by flavonoids. |
2002 |
Biosci. Biotechnol. Biochem. |
pmid:12224631
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Shimizu E and Ogata Y |
Activation of bone sialoprotein gene transcription by flavonoids is mediated through an inverted CCAAT box in ROS 17/2.8 cells. |
2002 |
J. Cell. Biochem. |
pmid:12112014
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Matsui T et al. |
Luteolin, a flavone, does not suppress postprandial glucose absorption through an inhibition of alpha-glucosidase action. |
2002 |
Biosci. Biotechnol. Biochem. |
pmid:12005074
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Cai H et al. |
A straightforward means of coupling preparative high-performance liquid chromatography and mass spectrometry. |
2002 |
Rapid Commun. Mass Spectrom. |
pmid:11870892
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Kahnberg P et al. |
Refinement and evaluation of a pharmacophore model for flavone derivatives binding to the benzodiazepine site of the GABA(A) receptor. |
2002 |
J. Med. Chem. |
pmid:12213060
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Vrielynck L et al. |
Self-modelling analysis applied to nanosecond transient absorption spectroscopy of flavone: an aid to elucidate and characterise reaction intermediates. |
2002 |
Spectrochim Acta A Mol Biomol Spectrosc |
pmid:12396046
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Choi MH et al. |
Determination of non-steroidal estrogens in breast milk, plasma, urine and hair by gas chromatography/mass spectrometry. |
2002 |
Rapid Commun. Mass Spectrom. |
pmid:12478564
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Horsman MR and Murata R |
Combination of vascular targeting agents with thermal or radiation therapy. |
2002 |
Int. J. Radiat. Oncol. Biol. Phys. |
pmid:12459380
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Manthey JA and Guthrie N |
Antiproliferative activities of citrus flavonoids against six human cancer cell lines. |
2002 |
J. Agric. Food Chem. |
pmid:12358447
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Van Hoorn DE et al. |
Accurate prediction of xanthine oxidase inhibition based on the structure of flavonoids. |
2002 |
Eur. J. Pharmacol. |
pmid:12231379
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Blatt CT et al. |
Cytotoxic flavonoids from the stem bark of Lonchocarpus aff. fluvialis. |
2002 |
Phytother Res |
pmid:12112286
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Choi J et al. |
Flavones from Scutellaria baicalensis Georgi attenuate apoptosis and protein oxidation in neuronal cell lines. |
2002 |
Biochim. Biophys. Acta |
pmid:12090934
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Rawel HM et al. |
Interactions of different phenolic acids and flavonoids with soy proteins. |
2002 |
Int. J. Biol. Macromol. |
pmid:12063116
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Voskresensky ON and Levitsky AP |
QSAR aspects of flavonoids as a plentiful source of new drugs. |
2002 |
Curr. Med. Chem. |
pmid:12132993
|
Fang J and Beattie DS |
Novel FMN-containing rotenone-insensitive NADH dehydrogenase from Trypanosoma brucei mitochondria: isolation and characterization. |
2002 |
Biochemistry |
pmid:11863445
|
López-Lázaro M |
Flavonoids as anticancer agents: structure-activity relationship study. |
2002 |
Curr Med Chem Anticancer Agents |
pmid:12678721
|
Marder M and Paladini AC |
GABA(A)-receptor ligands of flavonoid structure. |
2002 |
Curr Top Med Chem |
pmid:12171576
|
Cook SA and Shiemke AK |
Evidence that a type-2 NADH:quinone oxidoreductase mediates electron transfer to particulate methane monooxygenase in methylococcus capsulatus. |
2002 |
Arch. Biochem. Biophys. |
pmid:11811946
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