| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lymphedema | D008209 | 4 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Neoplasm Invasiveness | D009361 | 23 associated lipids |
| Neoplasms, Experimental | D009374 | 10 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
FLAVONE
FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.
Cross Reference
Introduction
To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with FLAVONE?
FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with FLAVONE
PubChem Associated disorders and diseases
What pathways are associated with FLAVONE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with FLAVONE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with FLAVONE?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with FLAVONE?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with FLAVONE?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with FLAVONE?
Knock-out
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with FLAVONE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Arya A et al. | Chloroform Fraction of Centratherum anthelminticum (L.) Seed Inhibits Tumor Necrosis Factor Alpha and Exhibits Pleotropic Bioactivities: Inhibitory Role in Human Tumor Cells. | 2012 | Evid Based Complement Alternat Med | pmid:22474512 |
| Ni F et al. | Flavonoid ampelopsin inhibits the growth and metastasis of prostate cancer in vitro and in mice. | 2012 | PLoS ONE | pmid:22693649 |
| Thomas CM et al. | Anti-neoplastic activity of two flavone isomers derived from Gnaphalium elegans and Achyrocline bogotensis. | 2012 | PLoS ONE | pmid:22768128 |
| Waki T et al. | Key role of chemical hardness to compare 2,2-diphenyl-1-picrylhydrazyl radical scavenging power of flavone and flavonol O-glycoside and C-glycoside derivatives. | 2012 | Chem. Pharm. Bull. | pmid:22223373 |
| Wang YL et al. | Anxiolytic-like effects of compound zhi zhu xiang in rats. | 2012 | Evid Based Complement Alternat Med | pmid:22690249 |
| Vermelho AB et al. | Microbial enzyme: applications in industry and in bioremediation. | 2012 | Enzyme Res | pmid:22496966 |
| Walch SG et al. | Holistic Control of Herbal Teas and Tinctures Based on Sage (Salvia officinalis L.) for Compounds with Beneficial and Adverse Effects using NMR Spectroscopy. | 2012 | Anal Chem Insights | pmid:22493561 |
| Ilboudo O et al. | Targeting structural motifs of flavonoid diglycosides using collision-induced dissociation experiments on flavonoid/Pb2+ complexes. | 2012 | Eur J Mass Spectrom (Chichester, Eng) | pmid:23221119 |
| Murata T et al. | Hyaluronidase inhibitors from Keiskea japonica. | 2012 | Chem. Pharm. Bull. | pmid:22223383 |
| Khan M et al. | Jaceosidin Induces Apoptosis in U87 Glioblastoma Cells through G2/M Phase Arrest. | 2012 | Evid Based Complement Alternat Med | pmid:22216058 |
| Wang D et al. | Study of the effects of total flavonoids of Astragalus on atherosclerosis formation and potential mechanisms. | 2012 | Oxid Med Cell Longev | pmid:22496932 |
| Brito I et al. | 4',5-Dihy-droxy-7-meth-oxy-flavanone dihydrate. | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22259537 |
| Ho YC et al. | Re-examination of chromogenic quantitative assays for determining flavonoid content. | 2012 | J. Agric. Food Chem. | pmid:22352692 |
| Barros L et al. | Characterization of phenolic compounds in flowers of wild medicinal plants from Northeastern Portugal. | 2012 | Food Chem. Toxicol. | pmid:22342808 |
| Khoobi M et al. | A facile route to flavone and neoflavone backbones via a regioselective palladium catalyzed oxidative Heck reaction. | 2012 | Chem. Commun. (Camb.) | pmid:22318701 |
| Lee HJ et al. | Protection of prenylated flavonoids from Mori Cortex Radicis (Moraceae) against nitric oxide-induced cell death in neuroblastoma SH-SY5Y cells. | 2012 | Arch. Pharm. Res. | pmid:22297755 |
| Spatafora C and Tringali C | Natural-derived polyphenols as potential anticancer agents. | 2012 | Anticancer Agents Med Chem | pmid:22292766 |
| Vauzour D | Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects. | 2012 | Oxid Med Cell Longev | pmid:22701758 |
| Rozza AL et al. | Morphologic and pharmacological investigations in the epicatechin gastroprotective effect. | 2012 | Evid Based Complement Alternat Med | pmid:22666296 |
| Malherbe CJ et al. | Development of on-line high performance liquid chromatography (HPLC)-biochemical detection methods as tools in the identification of bioactives. | 2012 | Int J Mol Sci | pmid:22489144 |