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Anti-inflammatory plant flavonoids and cellular action mechanisms. |
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Glucosylation of phenolic compounds by Pharbitis nil hairy roots: I. Glucosylation of coumarin and flavone derivatives. |
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Biosci. Biotechnol. Biochem. |
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Ching LM et al. |
Relationship between tumour endothelial cell apoptosis and tumour blood flow shutdown following treatment with the antivascular agent DMXAA in mice. |
2004 |
Br. J. Cancer |
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Inhibitory effect of flavonoids on N-acetylation of 5-aminosalicylic acid in cultured rat hepatocytes. |
2004 |
Biol. Pharm. Bull. |
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Flavopiridol inhibits NF-kappaB activation induced by various carcinogens and inflammatory agents through inhibition of IkappaBalpha kinase and p65 phosphorylation: abrogation of cyclin D1, cyclooxygenase-2, and matrix metalloprotease-9. |
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A hydroxyl group of flavonoids affects oral anti-inflammatory activity and inhibition of systemic tumor necrosis factor-alpha production. |
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Biosci. Biotechnol. Biochem. |
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Oxidative phosphorylation and rotenone-insensitive malate- and NADH-quinone oxidoreductases in Plasmodium yoelii yoelii mitochondria in situ. |
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Dietary polyphenols increase paraoxonase 1 gene expression by an aryl hydrocarbon receptor-dependent mechanism. |
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Mol. Cell. Biol. |
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In situ evidence of an alternative oxidase and an uncoupling protein in the respiratory chain of Aspergillus fumigatus. |
2004 |
Int. J. Biochem. Cell Biol. |
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Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. |
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Secondary metabolites from the leaves of Feijoa sellowiana Berg. |
2004 |
Phytochemistry |
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Induction of G1 cell cycle arrest in human umbilical vein endothelial cells by flavone's inhibition of the extracellular signal regulated kinase cascade. |
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Breast Cancer Res. |
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Studies on the flavones using liquid chromatography-electrospray ionization tandem mass spectrometry. |
2004 |
J Chromatogr A |
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Purification and characterization of an isoflavone-conjugates-hydrolyzing beta-glucosidase from endophytic bacterium. |
2004 |
J. Agric. Food Chem. |
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Characterisation of metabolites of the putative cancer chemopreventive agent quercetin and their effect on cyclo-oxygenase activity. |
2004 |
Br. J. Cancer |
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Flavones and polyphenols inhibit the NO pathway during apoptosis of leukemia B-cells. |
2004 |
Leuk. Res. |
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Inhibitory effect of flavonoids on sulfo- and glucurono-conjugation of acetaminophen in rat cultured hepatocytes and liver subcellular preparations. |
2004 |
Biol. Pharm. Bull. |
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Akao T et al. |
Enteric excretion of baicalein, a flavone of Scutellariae Radix, via glucuronidation in rat: involvement of multidrug resistance-associated protein 2. |
2004 |
Pharm. Res. |
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Effect of dietary flavonols on oestrogen receptor transactivation and cell death induction. |
2004 |
Br. J. Nutr. |
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Structure-activity relationships for alpha-glucosidase inhibition of baicalein, 5,6,7-trihydroxyflavone: the effect of A-ring substitution. |
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Biosci. Biotechnol. Biochem. |
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Oxidation and rearrangements of flavanones by mammalian cytochrome P450. |
2004 |
Xenobiotica |
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Swertisin dihydrate. |
2004 |
Acta Crystallogr C |
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Flavopiridol as a radio-sensitizer for esophageal cancer cell lines. |
2004 |
Dis. Esophagus |
pmid:15569374
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A new sesquiterpene from the fruits of Allophylus laevigatus. |
2004 |
Fitoterapia |
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Baicalin induces NAD(P)H:quinone reductase through the transactivation of AP-1 and NF-kappaB in Hepa 1c1c7 cells. |
2004 |
Eur. J. Cancer Prev. |
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Synthesis and aromatase inhibitory activity of novel pyridine-containing isoflavones. |
2004 |
J. Med. Chem. |
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Estimated phytochemical content of the dietary approaches to stop hypertension (DASH) diet is higher than in the Control Study Diet. |
2004 |
J Am Diet Assoc |
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The flavones luteolin and apigenin inhibit in vitro antigen-specific proliferation and interferon-gamma production by murine and human autoimmune T cells. |
2004 |
Biochem. Pharmacol. |
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Direct liquid chromatography-mass spectrometry method for the detection of glutathione S-transferase isozymes and investigation of their expression in response to dietary flavone. |
2004 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
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Kong X et al. |
Effects of Chinese herbal medicinal ingredients on peripheral lymphocyte proliferation and serum antibody titer after vaccination in chicken. |
2004 |
Int. Immunopharmacol. |
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Effect of flavonoids and vitamin E on cyclooxygenase-2 (COX-2) transcription. |
2004 |
Mutat. Res. |
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Flavonol and flavone intake and the risk of intermittent claudication in male smokers. |
2004 |
Eur. J. Epidemiol. |
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Stability control of senna leaves and senna extracts. |
2004 |
Planta Med. |
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The flavone hispidulin, a benzodiazepine receptor ligand with positive allosteric properties, traverses the blood-brain barrier and exhibits anticonvulsive effects. |
2004 |
Br. J. Pharmacol. |
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Two compounds from allelopathic rice accession and their inhibitory activity on weeds and fungal pathogens. |
2004 |
Phytochemistry |
pmid:15110693
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Sedative and sleep-enhancing properties of linarin, a flavonoid-isolated from Valeriana officinalis. |
2004 |
Pharmacol. Biochem. Behav. |
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Modulation of the activity of pro-inflammatory enzymes, COX-2 and iNOS, by chrysin derivatives. |
2004 |
Pharmacol. Res. |
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Investigation of the membrane localization and distribution of flavonoids by high-resolution magic angle spinning NMR spectroscopy. |
2004 |
Biochim. Biophys. Acta |
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A new flavone from Hypericum wightianum. |
2004 |
J Asian Nat Prod Res |
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Cross talk of cAMP and flavone in regulation of cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel and Na+/K+/2Cl- cotransporter in renal epithelial A6 cells. |
2004 |
Biochem. Pharmacol. |
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Neuroprotective effect of wogonin in hippocampal slice culture exposed to oxygen and glucose deprivation. |
2004 |
Eur. J. Pharmacol. |
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Phytochemicals inhibit catechol-O-methyltransferase activity in cytosolic fractions from healthy human mammary tissues: implications for catechol estrogen-induced DNA damage. |
2004 |
Toxicol. Sci. |
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Flavone glucosides with immunomodulatory activity from the leaves of Pleioblastus amarus. |
2004 |
Phytochemistry |
pmid:15081303
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Pharmacokinetics of baicalin in rats and its interactions with cyclosporin A, quinidine and SKF-525A: a microdialysis study. |
2004 |
Planta Med. |
pmid:15549664
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Early and late apoptosis events in human transformed and non-transformed colonocytes are independent on intracellular acidification. |
2004 |
Cell. Physiol. Biochem. |
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Isolation and purification of inflacoumarin A and licochalcone A from licorice by high-speed counter-current chromatography. |
2004 |
J Chromatogr A |
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Effect of flavonoids on feeding preference and development of the crucifer pest Mamestra configurata Walker. |
2004 |
J. Chem. Ecol. |
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Flavonoid inhibition of overexpressed human 3beta-hydroxysteroid dehydrogenase type II. |
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J. Steroid Biochem. Mol. Biol. |
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Identification of biomarkers for the initiation of apoptosis in human preneoplastic colonocytes by proteome analysis. |
2004 |
Int. J. Cancer |
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Badria FA and Zidan OA |
Natural products for dental caries prevention. |
2004 |
J Med Food |
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Flavone inhibition of tumor growth via apoptosis in vitro and in vivo. |
2004 |
Int. J. Oncol. |
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Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces cell cycle arrest in ras-transformed human mammary epithelial cells. |
2004 |
Biochem. Pharmacol. |
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Sato Y et al. |
Variation in synergistic activity by flavone and its related compounds on the increased susceptibility of various strains of methicillin-resistant Staphylococcus aureus to beta-lactam antibiotics. |
2004 |
Int. J. Antimicrob. Agents |
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Trypanocidal activity of Meliaceae and Rutaceae plant extracts. |
2004 |
Mem. Inst. Oswaldo Cruz |
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[Effects of flavone from leaves of Diospyros kaki on adventitial fibroblasts proliferation by advanced oxidation protein products in vitro]. |
2004 |
Zhong Yao Cai |
pmid:15272781
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Pleiotropic molecular effects of the pro-apoptotic dietary constituent flavone in human colon cancer cells identified by protein and mRNA expression profiling. |
2004 |
Proteomics |
pmid:15274140
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Enhanced bioavailability of paclitaxel after oral coadministration with flavone in rats. |
2004 |
Int J Pharm |
pmid:15081147
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Flumazenil-independent positive modulation of gamma-aminobutyric acid action by 6-methylflavone at human recombinant alpha1beta2gamma2L and alpha1beta2 GABAA receptors. |
2004 |
Eur. J. Pharmacol. |
pmid:15102527
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Wenzel U et al. |
Ascorbic acid suppresses drug-induced apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions. |
2004 |
Carcinogenesis |
pmid:14754875
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Blonska M et al. |
Effects of ethanol extract of propolis (EEP) and its flavones on inducible gene expression in J774A.1 macrophages. |
2004 |
J Ethnopharmacol |
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Inhibition of nitric oxide production from lipopolysaccharide-treated RAW 264.7 cells by synthetic flavones: structure-activity relationship and action mechanism. |
2004 |
Arch. Pharm. Res. |
pmid:15473664
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Acylated flavonoids and phenol glycosides from Veronica thymoides subsp. pseudocinerea. |
2004 |
Phytochemistry |
pmid:15381011
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Flavonoid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis. postulation of a biosynthetic pathway. |
2004 |
J. Agric. Food Chem. |
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Permeability characteristics and membrane affinity of flavonoids and alkyl gallates in Caco-2 cells and in phospholipid vesicles. |
2004 |
Arch. Biochem. Biophys. |
pmid:15111127
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Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells. |
2004 |
Biochem. Pharmacol. |
pmid:15041478
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Wang SP and Huang KJ |
Determination of flavonoids by high-performance liquid chromatography and capillary electrophoresis. |
2004 |
J Chromatogr A |
pmid:15065805
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McMullen MD et al. |
Salmon silk genes contribute to the elucidation of the flavone pathway in maize (Zea mays L.). |
2004 May-Jun |
J. Hered. |
pmid:15220389
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Fernández SP et al. |
Synergistic interaction between hesperidin, a natural flavonoid, and diazepam. |
2005 |
Eur. J. Pharmacol. |
pmid:15840404
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Rayyan S et al. |
Flavone C-glycosides from leaves of Oxalis triangularis. |
2005 |
J. Agric. Food Chem. |
pmid:16366694
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Effect of flavones on rat brain and lung matrix metalloproteinase activity measured by film in-situ zymography. |
2005 |
J. Pharm. Pharmacol. |
pmid:15831206
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[Study on extraction of zhuyun 3# by supercritical CO2]. |
2005 |
Zhong Yao Cai |
pmid:16104514
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Selective benzopyranone and pyrimido[2,1-a]isoquinolin-4-one inhibitors of DNA-dependent protein kinase: synthesis, structure-activity studies, and radiosensitization of a human tumor cell line in vitro. |
2005 |
J. Med. Chem. |
pmid:15658870
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Ebert B et al. |
Induction of phase-1 metabolizing enzymes by oltipraz, flavone and indole-3-carbinol enhance the formation and transport of benzo[a]pyrene sulfate conjugates in intestinal Caco-2 cells. |
2005 |
Toxicol. Lett. |
pmid:15890477
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Erhart LM et al. |
Flavone initiates a hierarchical activation of the caspase-cascade in colon cancer cells. |
2005 |
Apoptosis |
pmid:15909122
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Nakagawa-Goto K et al. |
Total synthesis and bioactivity of unique flavone desmosdumotin B and its analogs. |
2005 |
Bioorg. Med. Chem. Lett. |
pmid:15913998
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Wang TC et al. |
Synthesis, antiproliferative, and antiplatelet activities of oxime- and methyloxime-containing flavone and isoflavone derivatives. |
2005 |
Bioorg. Med. Chem. |
pmid:15990314
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Horvath CR et al. |
Identification and quantification of eight flavones in root and shoot tissues of the medicinal plant huang-qin (Scutellaria baicalensis Georgi) using high-performance liquid chromatography with diode array and mass spectrometric detection. |
2005 |
J Chromatogr A |
pmid:15679157
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Wenzel U et al. |
Increased mitochondrial palmitoylcarnitine/carnitine countertransport by flavone causes oxidative stress and apoptosis in colon cancer cells. |
2005 |
Cell. Mol. Life Sci. |
pmid:16314920
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Li BH et al. |
Structure-activity relationship of polyphenols that inhibit fatty acid synthase. |
2005 |
J. Biochem. |
pmid:16428296
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Protection against nuclear DNA damage offered by flavonoids in cells exposed to hydrogen peroxide: the role of iron chelation. |
2005 |
Free Radic. Biol. Med. |
pmid:16298684
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Radioiodinated flavones for in vivo imaging of beta-amyloid plaques in the brain. |
2005 |
J. Med. Chem. |
pmid:16279784
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Neuroactive flavonoids interacting with GABAA receptor complex. |
2005 |
Curr Drug Targets CNS Neurol Disord |
pmid:16266290
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Kim H et al. |
Effects of naturally occurring compounds on fibril formation and oxidative stress of beta-amyloid. |
2005 |
J. Agric. Food Chem. |
pmid:16248550
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Kovacic P |
Fundamental, electron transfer mechanism by pyrylium-type ions for the anticancer drugs 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and flavone-8-acetic acid (FAA). |
2005 |
Curr Med Chem Anticancer Agents |
pmid:16178775
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Rothwell JA et al. |
Experimental determination of octanol-water partition coefficients of quercetin and related flavonoids. |
2005 |
J. Agric. Food Chem. |
pmid:15913295
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Iori F et al. |
Theoretical quantitative structure-activity relationships of flavone ligands interacting with cytochrome P450 1A1 and 1A2 isozymes. |
2005 |
Bioorg. Med. Chem. |
pmid:15914008
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Han Y |
Ginkgo terpene component has an anti-inflammatory effect on Candida albicans-caused arthritic inflammation. |
2005 |
Int. Immunopharmacol. |
pmid:15829420
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Sawada Y and Ayabe S |
Multiple mutagenesis of P450 isoflavonoid synthase reveals a key active-site residue. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:15809082
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Malolanarasimhan K et al. |
Synthesis and biological study of a flavone acetic acid analogue containing an azido reporting group designed as a multifunctional binding site probe. |
2005 |
Bioorg. Med. Chem. |
pmid:15781383
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Ngadjui BT et al. |
Prenylated chalcones, flavone and other constituents of the twigs of Dorstenia angusticornis and Dorstenia barteri var. subtriangularis. |
2005 |
Phytochemistry |
pmid:15771891
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Zhang J and Brodbelt JS |
Silver complexation and tandem mass spectrometry for differentiation of isomeric flavonoid diglycosides. |
2005 |
Anal. Chem. |
pmid:15762583
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Göker H et al. |
Synthesis and potent antimicrobial activity of some novel 2-phenyl or methyl-4H-1-benzopyran-4-ones carrying amidinobenzimidazoles. |
2005 |
Bioorg. Med. Chem. |
pmid:15698788
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Nagai S et al. |
Kinetic study of the quenching reaction of singlet oxygen by flavonoids in ethanol solution. |
2005 |
J Phys Chem B |
pmid:16851486
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Likhitwitayawuid K et al. |
Phenolics with antiviral activity from Millettia erythrocalyx and Artocarpus lakoocha. |
2005 |
Nat. Prod. Res. |
pmid:15715263
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Wenzig E et al. |
Flavonolignans from Avena sativa. |
2005 |
J. Nat. Prod. |
pmid:15730266
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Budzianowski J et al. |
Lipophilic flavones of Primula veris L. from field cultivation and in vitro cultures. |
2005 |
Phytochemistry |
pmid:15896373
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Wenzel U et al. |
Activation of mitochondrial lactate uptake by flavone induces apoptosis in human colon cancer cells. |
2005 |
J. Cell. Physiol. |
pmid:15452831
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Åania-Pietrzak B et al. |
Modulation of MRP1 protein transport by plant, and synthetically modified flavonoids. |
2005 |
Life Sci. |
pmid:15916776
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Human gut microbial degradation of flavonoids: structure-function relationships. |
2005 |
J. Agric. Food Chem. |
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