FLAVONE

FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.

Cross Reference

Introduction

To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with FLAVONE?

FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with FLAVONE

MeSH term MeSH ID Detail
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Melanoma D008545 69 associated lipids
Asthma D001249 52 associated lipids
Glioma D005910 112 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with FLAVONE

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with FLAVONE?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with FLAVONE?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with FLAVONE?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with FLAVONE?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with FLAVONE?

Knock-out

Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Disease model

Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Animal Disease Models

Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with FLAVONE

Download all related citations
Per page 10 20 50 100 | Total 1492
Authors Title Published Journal PubMed Link
Kulevanova S et al. HPLC identification and determination of flavone aglycones in Helichrysum plicatum DC. (Asteraceae). 2000 Pharmazie pmid:11828624
Frangne N et al. Flavone glucoside uptake into barley mesophyll and Arabidopsis cell culture vacuoles. Energization occurs by H(+)-antiport and ATP-binding cassette-type mechanisms. 2002 Plant Physiol. pmid:11842175
Fang J and Beattie DS Novel FMN-containing rotenone-insensitive NADH dehydrogenase from Trypanosoma brucei mitochondria: isolation and characterization. 2002 Biochemistry pmid:11863445
Cai H et al. A straightforward means of coupling preparative high-performance liquid chromatography and mass spectrometry. 2002 Rapid Commun. Mass Spectrom. pmid:11870892
Rajendran NN et al. Modulation by insulin rather than blood glucose of the pain threshold in acute physiological and flavone induced antinociception in mice. 2001 Indian J. Exp. Biol. pmid:11883508
Isobe T et al. [Antibacterial constituents against Helicobacter pylori of Brazilian medicinal plant, Pariparoba]. 2002 Yakugaku Zasshi pmid:11968842
Kragh M et al. Acute effects of vascular modifying agents in solid tumors assessed by noninvasive laser Doppler flowmetry and near infrared spectroscopy. 2002 May-Jun Neoplasia pmid:11988846
Matsui T et al. Luteolin, a flavone, does not suppress postprandial glucose absorption through an inhibition of alpha-glucosidase action. 2002 Biosci. Biotechnol. Biochem. pmid:12005074
Hadjokas NE et al. Arginine to lysine 108 substitution in recombinant CYP1A2 abolishes methoxyresorufin metabolism in lymphoblastoid cells. 2002 Br. J. Pharmacol. pmid:12023936
Lin YM et al. Chalcones and flavonoids as anti-tuberculosis agents. 2002 Bioorg. Med. Chem. pmid:12057669