| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
FLAVONE
FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.
Cross Reference
Introduction
To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with FLAVONE?
FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with FLAVONE
PubChem Associated disorders and diseases
What pathways are associated with FLAVONE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with FLAVONE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with FLAVONE?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with FLAVONE?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with FLAVONE?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with FLAVONE?
Knock-out
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with FLAVONE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Baranowska I and Raróg D | Application of derivative spectrophotometry to determination of flavonoid mixtures. | 2001 | Talanta | pmid:18968363 |
| Böcker D and Verspohl EJ | Role of protein kinase C, PI3-kinase and tyrosine kinase in activation of MAP kinase by glucose and agonists of G-protein coupled receptors in INS-1 cells. | 2001 | Int. J. Exp. Diabetes Res. | pmid:12369712 |
| Saarinen N et al. | No evidence for the in vivo activity of aromatase-inhibiting flavonoids. | 2001 | J. Steroid Biochem. Mol. Biol. | pmid:11595503 |
| Rajendran NN et al. | Modulation by insulin rather than blood glucose of the pain threshold in acute physiological and flavone induced antinociception in mice. | 2001 | Indian J. Exp. Biol. | pmid:11883508 |
| Kim SJ | Effect of biflavones of Ginkgo biloba against UVB-induced cytotoxicity in vitro. | 2001 | J. Dermatol. | pmid:11449670 |
| Seo HJ and Surh YJ | Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces apoptosis in human promyelocytic leukemia cells. | 2001 | Mutat. Res. | pmid:11551495 |
| Andrade-Cetto A and Wiedenfeld H | Hypoglycemic effect of Cecropia obtusifolia on streptozotocin diabetic rats. | 2001 | J Ethnopharmacol | pmid:11694359 |
| Chung MI et al. | Synthesis, antiplatelet and vasorelaxing effects of monooxygenated flavones and flavonoxypropanolamines. | 2001 | J. Pharm. Pharmacol. | pmid:11804390 |
| Kestell P et al. | Measurement of plasma 5-hydroxyindoleacetic acid as a possible clinical surrogate marker for the action of antivascular agents. | 2001 | Clin. Chim. Acta | pmid:11718691 |
| Hirvonen T et al. | Flavonol and flavone intake and the risk of cancer in male smokers (Finland). | 2001 | Cancer Causes Control | pmid:11714106 |
| Philpott M et al. | The antitumour agent 5,6-dimethylxanthenone-4-acetic acid acts in vitro on human mononuclear cells as a co-stimulator with other inducers of tumour necrosis factor. | 2001 | Eur. J. Cancer | pmid:11576850 |
| Mcmullen MD et al. | The biological basis of epistasis between quantitative trait loci for flavone and 3-deoxyanthocyanin synthesis in maize (Zea mays L.). | 2001 | Genome | pmid:11550903 |
| Kumazawa T et al. | Synthesis of 8-C-glucosylflavones. | 2001 | Carbohydr. Res. | pmid:11513825 |
| Pepper C et al. | Flavopiridol circumvents Bcl-2 family mediated inhibition of apoptosis and drug resistance in B-cell chronic lymphocytic leukaemia. | 2001 | Br. J. Haematol. | pmid:11472347 |
| MarÃn FR and Del RÃo JA | Selection of hybrids and edible citrus species with a high content in the diosmin functional compound. Modulating effect of plant growth regulators on contents. | 2001 | J. Agric. Food Chem. | pmid:11453775 |
| D'arc Felicio J et al. | Biflavonoids from Ouratea multiflora. | 2001 | Fitoterapia | pmid:11395278 |
| Stochmal A et al. | Acylated apigenin glycosides from alfalfa (Medicago sativa L.) var. Artal. | 2001 | Phytochemistry | pmid:11454348 |
| Lee SE et al. | Inhibitory effects of naturally occurring compounds on aflatoxin B(1) biotransformation. | 2001 | J. Agric. Food Chem. | pmid:11714299 |
| Schrag ML and Wienkers LC | Covalent alteration of the CYP3A4 active site: evidence for multiple substrate binding domains. | 2001 | Arch. Biochem. Biophys. | pmid:11414684 |
| Tabak C et al. | Chronic obstructive pulmonary disease and intake of catechins, flavonols, and flavones: the MORGEN Study. | 2001 | Am. J. Respir. Crit. Care Med. | pmid:11435239 |