MeSH term | MeSH ID | Detail |
---|---|---|
Stomach Ulcer | D013276 | 75 associated lipids |
Weight Loss | D015431 | 56 associated lipids |
FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.
To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with FLAVONE
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Berim A et al. | Unexpected roles for ancient proteins: flavone 8-hydroxylase in sweet basil trichomes is a Rieske-type, PAO-family oxygenase. | 2014 | Plant J. | pmid:25139498 |
Goyal N et al. | Ethynylflavones, highly potent, and selective inhibitors of cytochrome P450 1A1. | 2014 | Chem. Res. Toxicol. | pmid:25033111 |
Prasad VG et al. | Iminoflavones combat 1,2-dimethyl hydrazine-induced aberrant crypt foci development in colon cancer. | 2014 | Biomed Res Int | pmid:24995310 |
Li LZ et al. | Flavonoids and other constituents from Aletris spicata and their chemotaxonomic significance. | 2014 | Nat. Prod. Res. | pmid:24896299 |
Wang MH et al. | A new antioxidant flavone glycoside from Scutellaria baicalensis Georgi. | 2014 | Nat. Prod. Res. | pmid:24995563 |
Ahmed N et al. | Design, synthesis and antiproliferative activity of functionalized flavone-triazole-tetrahydropyran conjugates against human cancer cell lines. | 2014 | Eur J Med Chem | pmid:24941129 |
Raghav N and Garg S | SAR studies of o-hydroxychalcones and their cyclized analogs and study them as novel inhibitors of cathepsin B and cathepsin H. | 2014 | Eur J Pharm Sci | pmid:24780403 |
Berczyński P et al. | Studies on the antioxidant activity of some thiazolidinedione, imidazolidinedione and rhodanine derivatives having a flavone core. | 2014 | Luminescence | pmid:24733694 |
Venditti A et al. | A C-methylated resacetophenone from Cistus monspeliensis L. | 2014 | Fitoterapia | pmid:24685506 |
Lin SH and Shih YW | Antitumor effects of the flavone chalcone: inhibition of invasion and migration through the FAK/JNK signaling pathway in human gastric adenocarcinoma AGS cells. | 2014 | Mol. Cell. Biochem. | pmid:24510324 |