MeSH term | MeSH ID | Detail |
---|---|---|
Stomach Ulcer | D013276 | 75 associated lipids |
Weight Loss | D015431 | 56 associated lipids |
FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.
To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with FLAVONE
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Modelli A and Pshenichnyuk SA | Gas-phase dissociative electron attachment to flavonoids and possible similarities to their metabolic pathways. | 2013 | Phys Chem Chem Phys | pmid:23243660 |
Golub AG et al. | Discovery and characterization of synthetic 4'-hydroxyflavones-New CK2 inhibitors from flavone family. | 2013 | Bioorg. Med. Chem. | pmid:24011954 |
D'Abrosca B et al. | A new acylated flavone glycoside with antioxidant and radical scavenging activities from Teucrium polium leaves. | 2013 | Nat. Prod. Res. | pmid:22708583 |
Choe H et al. | Structure-based design of flavone-based inhibitors of wild-type and T315I mutant of ABL. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23790540 |
Richter D et al. | Effects of phytoestrogen extracts isolated from pumpkin seeds on estradiol production and ER/PR expression in breast cancer and trophoblast tumor cells. | 2013 | Nutr Cancer | pmid:23859042 |
Hapuarachchi SD et al. | Andrographidine G, a new flavone glucoside from Andrographis paniculata. | 2013 | Nat Prod Commun | pmid:23678804 |
Yin FZ et al. | [Optimization of preparation of salt-processed psoraleae fructus medicines with multi-index orthogonal method]. | 2013 | Zhongguo Zhong Yao Za Zhi | pmid:23668006 |
Zhang JY et al. | [Rapid recognition and identification of chemical constituents in Qinghuo Zhimai tablets by SPE-HPLC-ESI-MS(n)]. | 2013 | Zhongguo Zhong Yao Za Zhi | pmid:23672039 |
Wang BL et al. | Treating acute cystitis with biodegradable micelle-encapsulated quercetin. | 2012 | Int J Nanomedicine | pmid:22661886 |
Lee DH et al. | Flavonoids Isolated from Korea Citrus aurantium L. Induce G2/M Phase Arrest and Apoptosis in Human Gastric Cancer AGS Cells. | 2012 | Evid Based Complement Alternat Med | pmid:22194772 |
Lee H et al. | Angelicae Dahuricae Radix Inhibits Dust Mite Extract-Induced Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice. | 2012 | Evid Based Complement Alternat Med | pmid:22454682 |
Wang J et al. | Rapid Screening for Flavone C-Glycosides in the Leaves of Different Species of Bamboo and Simultaneous Quantitation of Four Marker Compounds by HPLC-UV/DAD. | 2012 | Int J Anal Chem | pmid:22654910 |
Liu Y et al. | Chinese herb and formulas for promoting blood circulation and removing blood stasis and antiplatelet therapies. | 2012 | Evid Based Complement Alternat Med | pmid:22454656 |
Khan R et al. | Chrysin protects against cisplatin-induced colon. toxicity via amelioration of oxidative stress and apoptosis: probable role of p38MAPK and p53. | 2012 | Toxicol. Appl. Pharmacol. | pmid:22155348 |
Chen YH et al. | Evaluation of the structure-activity relationship of flavonoids as antioxidants and toxicants of zebrafish larvae. | 2012 | Food Chem | pmid:23107683 |
Bandaruk Y et al. | Evaluation of the inhibitory effects of quercetin-related flavonoids and tea catechins on the monoamine oxidase-A reaction in mouse brain mitochondria. | 2012 | J. Agric. Food Chem. | pmid:23009399 |
Kanda K et al. | Nobiletin suppresses adipocyte differentiation of 3T3-L1 cells by an insulin and IBMX mixture induction. | 2012 | Biochim. Biophys. Acta | pmid:22172985 |
de-Faria FM et al. | Antioxidant action of mangrove polyphenols against gastric damage induced by absolute ethanol and ischemia-reperfusion in the rat. | 2012 | ScientificWorldJournal | pmid:22654592 |
Kongkum N et al. | DNA topoisomerase IIα inhibitory and anti-HIV-1 flavones from leaves and twigs of Gardenia carinata. | 2012 | Fitoterapia | pmid:22155186 |
Rahigude A et al. | Participation of antioxidant and cholinergic system in protective effect of naringenin against type-2 diabetes-induced memory dysfunction in rats. | 2012 | Neuroscience | pmid:22999973 |