MeSH term | MeSH ID | Detail |
---|---|---|
Neoplasm Invasiveness | D009361 | 23 associated lipids |
Lymphedema | D008209 | 4 associated lipids |
FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.
To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with FLAVONE
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kassem ME et al. | A sulphated flavone glycoside from Livistona australis and its antioxidant and cytotoxic activity. | 2012 | Nat. Prod. Res. | pmid:21793764 |
Guo AJ et al. | Kaempferol as a flavonoid induces osteoblastic differentiation via estrogen receptor signaling. | 2012 | Chin Med | pmid:22546174 |
Welch A et al. | Habitual flavonoid intakes are positively associated with bone mineral density in women. | 2012 | J. Bone Miner. Res. | pmid:22549983 |
Yarmolinsky L et al. | Potent antiviral flavone glycosides from Ficus benjamina leaves. | 2012 | Fitoterapia | pmid:22155188 |
Clark BR et al. | Flavone C-glycosides from Anthurium andraeanum. | 2012 | Nat Prod Commun | pmid:22816298 |
Chan LP et al. | Apigenin induces apoptosis via tumor necrosis factor receptor- and Bcl-2-mediated pathway and enhances susceptibility of head and neck squamous cell carcinoma to 5-fluorouracil and cisplatin. | 2012 | Biochim. Biophys. Acta | pmid:22554915 |
Wang Y et al. | Flavone C-glycosides from the leaves of Lophatherum gracile and their in vitro antiviral activity. | 2012 | Planta Med. | pmid:21870321 |
Xiao L et al. | Transcriptome of protoplasts reprogrammed into stem cells in Physcomitrella patens. | 2012 | PLoS ONE | pmid:22545152 |
Begum N et al. | Apigenin ameliorates gamma radiation-induced cytogenetic alterations in cultured human blood lymphocytes. | 2012 | Mutat. Res. | pmid:22516036 |
Duchnowicz P et al. | Hypolipidemic and antioxidant effects of hydroxycinnamic acids, quercetin, and cyanidin 3-glucoside in hypercholesterolemic erythrocytes (in vitro study). | 2012 | Eur J Nutr | pmid:21755326 |