MeSH term | MeSH ID | Detail |
---|---|---|
Neoplasm Invasiveness | D009361 | 23 associated lipids |
Lymphedema | D008209 | 4 associated lipids |
FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.
To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with FLAVONE
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Zhang BH et al. | [The effects of the total flavone of Ku-shen on cardiac arrhythmias (author's transl)]. | 1979 | Yao Xue Xue Bao | pmid:532643 |
Takido M et al. | [On the revised structure of skullcapflavone I, a flavone compound in the roots of Scutellaria baicalensis Georgi (Wogon) (author's transl)]. | 1979 | Yakugaku Zasshi | pmid:480145 |
Matusuura S et al. | [Synthesis studies of the flavone derivates. III. Photochemical reaction of chalcone derivative (author's transl)]. | 1976 | Yakugaku Zasshi | pmid:986458 |
Iinuma M and Matsuura S | [Synthetic studies of the flavone derivatives. VI. The synthesis of skullcapflavone I, II and related flavones (author's transl)]. | 1979 | Yakugaku Zasshi | pmid:536899 |
Ogawa M and Ogihara Y | [Studies on the constituents of Enkianthus nudipes. IV. A new flavone glucoside from the stems (author's transl)]. | 1975 | Yakugaku Zasshi | pmid:1237562 |
Matsuura S and Kunii T | [Synthetic studies of the flavone derivatives. II. Synthesis of cirsimaritin (author's transl)]. | 1974 | Yakugaku Zasshi | pmid:4473114 |
Isobe T et al. | [Antibacterial constituents against Helicobacter pylori of Brazilian medicinal plant, Pariparoba]. | 2002 | Yakugaku Zasshi | pmid:11968842 |
Iinuma M and Matsuura S | [Synthetic studies of the flavone derivatives. VII. Synthesis of 6,8-dimethoxyflavone derivatives and their 13C-NMR (author's transl)]. | 1980 | Yakugaku Zasshi | pmid:7463312 |
Luo P et al. | Scutellarin isolated from Erigeron multiradiatus inhibits high glucose-mediated vascular inflammation. | 2008 | Yakugaku Zasshi | pmid:18758143 |
Gao D et al. | Hypoglycemic effects and mechanisms of action of Cortex Lycii Radicis on alloxan-induced diabetic mice. | 2007 | Yakugaku Zasshi | pmid:17917429 |